ES2035317T3 - Un metodo para la deteccion y el analisis de celulas hematopoyeticas en una muestra. - Google Patents
Un metodo para la deteccion y el analisis de celulas hematopoyeticas en una muestra.Info
- Publication number
- ES2035317T3 ES2035317T3 ES198888310507T ES88310507T ES2035317T3 ES 2035317 T3 ES2035317 T3 ES 2035317T3 ES 198888310507 T ES198888310507 T ES 198888310507T ES 88310507 T ES88310507 T ES 88310507T ES 2035317 T3 ES2035317 T3 ES 2035317T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- analysis
- detection
- cells
- hematopoyetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 230000001785 maturational effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UN METODO Y CONJUNTO PARA LA IDENTIFICACION DE ORIGENES Y ETAPAS DE CELULAS HEMATOPOYETICAS EN UNA MUESTRA, DONDE LAS CELULAS SE TRATAN CON ANTICUERPOS MONOCLONALES MARCADOS ELEGIDOS PARA DISTINGUIR ENTRE CADA ORIGEN Y ETAPAS DE MADURACION DENTRO DE CADA ORIGEN.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11849887A | 1987-11-09 | 1987-11-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2035317T3 true ES2035317T3 (es) | 1993-04-16 |
| ES2035317T5 ES2035317T5 (es) | 1998-03-16 |
Family
ID=22378975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88310507T Expired - Lifetime ES2035317T5 (es) | 1987-11-09 | 1988-11-08 | Metodo para analizar celulas hematopoyeticas en una muestra. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5137809A (es) |
| EP (1) | EP0317156B2 (es) |
| JP (1) | JPH06105253B2 (es) |
| AT (1) | ATE81724T1 (es) |
| DE (1) | DE3875456T3 (es) |
| ES (1) | ES2035317T5 (es) |
| GR (2) | GR3006183T3 (es) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991013974A1 (en) * | 1990-03-14 | 1991-09-19 | The Biomembrane Institute | Monoclonal antibody and immunoconjugates for the treatment and detection of b cell disorders |
| US5622853A (en) * | 1990-05-01 | 1997-04-22 | Becton Dickinson And Company | T lymphocyte precursor |
| US5367057A (en) | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
| US5185438A (en) * | 1991-04-02 | 1993-02-09 | The Trustees Of Princeton University | Nucleic acids encoding hencatoporetic stem cell receptor flk-2 |
| GR920100123A (el) * | 1991-04-12 | 1993-03-16 | Ortho Diagnostic Systems Inc | Αντιδραστήριο πολυχρωματικής κηλίδωσης και μέ?οδος ανάλυσης. |
| FR2676847A1 (fr) * | 1991-05-22 | 1992-11-27 | Immunotech Sa | Procede d'enumeration des reticulocytes et les kits destines a cette enumeration. |
| FR2684186B1 (fr) * | 1991-11-25 | 1994-02-25 | Pasteur Sanofi Diagnostics | Trousse pour le denombrement rapide des granulocytes, et procede utilisant ladite trousse. |
| ES2051651B1 (es) * | 1992-12-10 | 1995-01-01 | Univ Salamanca | Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones. |
| US5692220A (en) * | 1993-09-02 | 1997-11-25 | Coulter Corporation | Decision support system and method for diagnosis consultation in laboratory hematopathology |
| WO1995013540A1 (en) * | 1993-11-12 | 1995-05-18 | Becton Dickinson And Company | Method for absolute counting of rare cells |
| FI951778A7 (fi) * | 1995-04-12 | 1996-10-13 | Oy Aboatech Ab | Menetelmä allergian toteamiseksi |
| US5876956A (en) * | 1995-05-15 | 1999-03-02 | Johns Hopkins University School Of Medicine | Methods for identification or purification of cells containing an enzymatic intracellular marker |
| US5877299A (en) * | 1995-06-16 | 1999-03-02 | Stemcell Technologies Inc. | Methods for preparing enriched human hematopoietic cell preparations |
| US6306575B1 (en) | 1995-06-16 | 2001-10-23 | Stemcell Technologies, Inc. | Methods for preparing enriched human hematopoietic cell preparations |
| US6117985A (en) | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
| PT877941E (pt) * | 1995-11-13 | 2003-07-31 | Biotransplant Inc | Metodo para enriquecimento em volume de uma populacao ou subpopulacao de celulas |
| AU721792B2 (en) * | 1996-09-06 | 2000-07-13 | Medarex, Inc. | Cyanidin compositions and therapeutic and diagnostic uses therefor |
| JP3620946B2 (ja) | 1997-03-17 | 2005-02-16 | シスメックス株式会社 | スキャッタグラムの表示方法および粒子計測装置 |
| AU3862200A (en) * | 1999-03-01 | 2000-09-21 | Board Of Trustees Of The Leland Stanford Junior University | Rapid assay for infection in small children |
| WO2000052471A1 (en) * | 1999-03-01 | 2000-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | Rapid assay for chorioamnionitis |
| DE50015293D1 (de) * | 1999-04-13 | 2008-09-11 | Wilex Ag | Diagnostischer und therapeutischer Einsatz von Antikörpern gegen den Urokinase-Rezeptor |
| US6900023B1 (en) | 1999-09-02 | 2005-05-31 | Sysmex Corporation | Method for classifying and counting leukocytes |
| US7300763B2 (en) | 2000-06-08 | 2007-11-27 | Teijin Limited | Method of testing myelotoxicity with the use of flow cytometer |
| US7393656B2 (en) * | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
| US7695926B2 (en) | 2001-07-10 | 2010-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting receptor-ligand interactions in single cells |
| US7381535B2 (en) * | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
| US7563584B2 (en) | 2001-07-10 | 2009-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting the activation state of multiple proteins in single cells |
| PT1363126E (pt) * | 2002-05-14 | 2006-05-31 | Univ Salamanca | Analise multidimensional diferencial de leucocitos |
| NZ537220A (en) * | 2002-05-16 | 2008-06-30 | Absorber Ab | Method of isolating an endothelial cell and method of donor specific crossmatching |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| NZ537277A (en) * | 2002-07-18 | 2008-04-30 | Crucell Holland Bv | Recombinant production of mixtures of antibodies |
| US7507548B2 (en) | 2003-03-04 | 2009-03-24 | University Of Salamanca | Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
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| EP1737971B1 (en) | 2004-01-20 | 2017-08-16 | Merus N.V. | Mixtures of binding proteins |
| ES2521620T3 (es) * | 2004-03-03 | 2014-11-13 | Universidad De Salamanca | Método para la detección multidimensional de fenotipos aberrantes en células neoplásicas para su uso para monitorizar niveles mínimos de enfermedad utilizando citometría de flujo |
| EP1737949B1 (en) * | 2004-03-09 | 2010-09-15 | Absorber AB | Endothelial progenitor cells and methods of use thereof |
| US7674598B2 (en) | 2004-05-21 | 2010-03-09 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
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| JP3968383B2 (ja) * | 2004-09-01 | 2007-08-29 | 株式会社日本メディカル総研 | 血液細胞の新規分類法ならびにそれを利用したテイラーメード治療および予防 |
| US8252587B2 (en) | 2004-10-25 | 2012-08-28 | Celerant Therapeutics, Inc. | Methods of expanding myeloid cell populations and uses thereof |
| EP2377555A3 (en) | 2004-11-18 | 2011-11-23 | Imclone LLC | Antibodies against vascular endothelial growth factor receptor-1 |
| AU2006206159A1 (en) * | 2005-01-24 | 2006-07-27 | Massachusetts Institute Of Technology | Method for modeling cell signaling systems by means of bayesian networks |
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| ES2905545T3 (es) | 2010-01-06 | 2022-04-11 | Takeda Pharmaceuticals Co | Proteínas de unión a calicreína plasmática |
| CN103328500B (zh) | 2010-08-04 | 2018-01-26 | 西兹尔生物技术有限公司 | 用于癌症的诊断和治疗的方法和化合物 |
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| KR102466885B1 (ko) | 2013-01-09 | 2022-11-11 | 유나이티드 세러퓨틱스 코오포레이션 | 프로스타시클린 및 중간엽 줄기 세포를 사용한 혈관병증의 치료 |
| EA035338B1 (ru) | 2013-10-24 | 2020-05-29 | Нёропласт Бехер Б.В. | Композиция гемопоэтических стволовых клеток с пониженной воспалительной активностью, ее получение и применение |
| CN108350419A (zh) | 2015-07-20 | 2018-07-31 | 安吉克莱茵生物科学有限公司 | 干细胞移植方法和干细胞移植组合物 |
| WO2017066561A2 (en) | 2015-10-16 | 2017-04-20 | President And Fellows Of Harvard College | Regulatory t cell pd-1 modulation for regulating t cell effector immune responses |
| JP2019512271A (ja) | 2016-03-21 | 2019-05-16 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | T細胞疲弊状態特異的遺伝子発現調節因子およびその使用 |
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| JP7179723B2 (ja) | 2016-10-24 | 2022-11-29 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニルによるmscの免疫調節特性の増強 |
| JP7536450B2 (ja) | 2017-06-05 | 2024-08-20 | ベクトン・ディキンソン・アンド・カンパニー | 単一細胞用のサンプルインデックス付加 |
| US12227548B2 (en) | 2018-11-19 | 2025-02-18 | Dana-Farber Cancer Institute, Inc. | Use of IRE1α-XBP1 signaling pathway biomarkers for modulating immune responses |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| EP4055160B1 (en) | 2019-11-08 | 2024-04-10 | Becton Dickinson and Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
| CN115279919A (zh) | 2020-01-13 | 2022-11-01 | 贝克顿迪金森公司 | 使用含有du的寡核苷酸的细胞捕获 |
| WO2021155057A1 (en) | 2020-01-29 | 2021-08-05 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| US12153043B2 (en) * | 2020-02-25 | 2024-11-26 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| WO2021231779A1 (en) | 2020-05-14 | 2021-11-18 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
| CN115803445A (zh) | 2020-06-02 | 2023-03-14 | 贝克顿迪金森公司 | 用于5撇基因表达测定的寡核苷酸和珠 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022026909A1 (en) | 2020-07-31 | 2022-02-03 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| CN116685850A (zh) | 2020-12-15 | 2023-09-01 | 贝克顿迪金森公司 | 单细胞分泌组分析 |
| US20250319183A1 (en) | 2021-04-07 | 2025-10-16 | David Avigan | Compositions and methods for the treatment of cancer |
| WO2023086969A2 (en) | 2021-11-12 | 2023-05-19 | Ichor Medical Systems Inc. | Treatment methods |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53107413A (en) * | 1977-03-02 | 1978-09-19 | Nippon Baiotesuto Kenkiyuushiy | Detecting method and reagent kit for antibody against leucocyte |
| GB2057685B (en) * | 1979-03-19 | 1983-12-21 | Int Diagnostic Tech | Double tagged immunoassay |
| JPS5745454A (en) * | 1980-09-02 | 1982-03-15 | Fuji Photo Film Co Ltd | Immunochemical measuring method for various minor components |
| JPS58171671A (ja) * | 1982-04-01 | 1983-10-08 | Fujitsu Ltd | 細胞分類方法 |
| US4607007A (en) * | 1983-04-07 | 1986-08-19 | Becton, Dickinson And Company | Differentiation of natural killer cell subpopulations of cells |
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| US4599307A (en) * | 1983-07-18 | 1986-07-08 | Becton, Dickinson And Company | Method for elimination of selected cell populations in analytic cytology |
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-
1988
- 1988-11-08 AT AT88310507T patent/ATE81724T1/de not_active IP Right Cessation
- 1988-11-08 DE DE3875456T patent/DE3875456T3/de not_active Expired - Lifetime
- 1988-11-08 ES ES88310507T patent/ES2035317T5/es not_active Expired - Lifetime
- 1988-11-08 EP EP88310507A patent/EP0317156B2/en not_active Expired - Lifetime
- 1988-11-09 JP JP63283547A patent/JPH06105253B2/ja not_active Expired - Lifetime
-
1990
- 1990-07-19 US US07/572,303 patent/US5137809A/en not_active Expired - Lifetime
-
1992
- 1992-11-05 GR GR920402504T patent/GR3006183T3/el unknown
-
1998
- 1998-01-14 GR GR980400074T patent/GR3025901T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0317156A1 (en) | 1989-05-24 |
| JPH01161153A (ja) | 1989-06-23 |
| GR3006183T3 (en) | 1993-06-21 |
| GR3025901T3 (en) | 1998-04-30 |
| EP0317156B2 (en) | 1997-11-12 |
| US5137809A (en) | 1992-08-11 |
| ES2035317T5 (es) | 1998-03-16 |
| DE3875456T2 (de) | 1993-03-04 |
| EP0317156B1 (en) | 1992-10-21 |
| JPH06105253B2 (ja) | 1994-12-21 |
| ATE81724T1 (de) | 1992-11-15 |
| DE3875456T3 (de) | 1998-06-10 |
| DE3875456D1 (de) | 1992-11-26 |
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