ES2043716T3 - Formas de administracion oral con liberacion retardada. - Google Patents
Formas de administracion oral con liberacion retardada.Info
- Publication number
- ES2043716T3 ES2043716T3 ES88107021T ES88107021T ES2043716T3 ES 2043716 T3 ES2043716 T3 ES 2043716T3 ES 88107021 T ES88107021 T ES 88107021T ES 88107021 T ES88107021 T ES 88107021T ES 2043716 T3 ES2043716 T3 ES 2043716T3
- Authority
- ES
- Spain
- Prior art keywords
- delayed release
- oral administration
- forms
- carbamazepine
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003111 delayed effect Effects 0.000 title abstract 3
- FFGPTBGBLSHEPO-UHFFFAOYSA-N carbamazepine Chemical compound C1=CC2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 FFGPTBGBLSHEPO-UHFFFAOYSA-N 0.000 abstract 2
- 229960000623 carbamazepine Drugs 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 1
- 150000004683 dihydrates Chemical class 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
EL OBJETO DE LA PRESENTE INVENCION SON FORMAS DE ADMINISTRACION ORAL MEJORADAS, P.E. JARABES, CON LIBERACION RETARDADA DE CARBAMAZEPINA. LA LIBERACION RETARDADA DE CARBAMAZEPINA SE CONSIGUE MEDIANTE LA ELABORACION DE UNA FORMA CRISTALINA CUBICA DE TAMAÑO ADECUADO DE LOS CRISTALES DE DIHIDRATO CONTENIDOS EN LA FORMA DE ADMINISTRACION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH168287 | 1987-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2043716T3 true ES2043716T3 (es) | 1994-01-01 |
Family
ID=4216129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88107021T Expired - Lifetime ES2043716T3 (es) | 1987-05-04 | 1988-05-02 | Formas de administracion oral con liberacion retardada. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5122543A (es) |
| EP (1) | EP0289977B1 (es) |
| JP (1) | JPH01131117A (es) |
| KR (1) | KR960006059B1 (es) |
| AT (1) | ATE94390T1 (es) |
| AU (1) | AU619178B2 (es) |
| CA (1) | CA1328219C (es) |
| DD (1) | DD269784A5 (es) |
| DE (1) | DE3884044D1 (es) |
| DK (1) | DK169608B1 (es) |
| ES (1) | ES2043716T3 (es) |
| FI (1) | FI882044A7 (es) |
| HU (1) | HU199074B (es) |
| IE (1) | IE63081B1 (es) |
| IL (1) | IL86211A (es) |
| MX (1) | MX11339A (es) |
| NO (1) | NO881933L (es) |
| NZ (1) | NZ224476A (es) |
| PH (1) | PH24895A (es) |
| PT (1) | PT87381B (es) |
| ZA (1) | ZA883135B (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| DE4210711A1 (de) * | 1991-10-31 | 1993-05-06 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De | Transdermale therapeutische systeme mit kristallisationsinhibitoren |
| US5676968A (en) * | 1991-10-31 | 1997-10-14 | Schering Aktiengesellschaft | Transdermal therapeutic systems with crystallization inhibitors |
| DE4422881A1 (de) * | 1993-10-25 | 1995-04-27 | Bayer Ag | Kolloidal dispergierbare Wirkstoff-Formulierungen |
| CA2185803C (en) * | 1994-03-18 | 2006-07-11 | Edward M. Rudnic | Emulsified drug delivery systems |
| DE4423078B4 (de) * | 1994-07-01 | 2005-01-13 | Awd.Pharma Gmbh & Co. Kg | Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung |
| WO1999031987A1 (en) * | 1997-12-19 | 1999-07-01 | Taro Pharmaceuticals U.S.A., Inc. | Topical carbamazepine formulations and methods of use |
| GB9930058D0 (en) * | 1999-12-20 | 2000-02-09 | Novartis Ag | Organic compounds |
| US7193084B2 (en) * | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
| US20040022862A1 (en) * | 2000-12-22 | 2004-02-05 | Kipp James E. | Method for preparing small particles |
| US6977085B2 (en) * | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
| US20050048126A1 (en) * | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
| US8067032B2 (en) * | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| US6607784B2 (en) * | 2000-12-22 | 2003-08-19 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| AU2002249836B2 (en) * | 2000-12-22 | 2006-12-14 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US6951656B2 (en) * | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US9700866B2 (en) * | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| US20030072807A1 (en) * | 2000-12-22 | 2003-04-17 | Wong Joseph Chung-Tak | Solid particulate antifungal compositions for pharmaceutical use |
| US20040256749A1 (en) * | 2000-12-22 | 2004-12-23 | Mahesh Chaubal | Process for production of essentially solvent-free small particles |
| IN190699B (es) | 2001-02-02 | 2003-08-16 | Sun Pharmaceutical Ind Ltd | |
| US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
| AU2002337692B2 (en) * | 2001-09-26 | 2007-09-13 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
| US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
| AU2003231919A1 (en) * | 2002-03-14 | 2003-09-22 | Sun Pharmaceutical Industries Limited | Oral controlled drug delivery system containing carbamazepine |
| MX2007015183A (es) * | 2005-06-14 | 2008-02-19 | Baxter Int | Formulaciones farmaceuticas para minimizar las interacciones farmaco-farmaco. |
| US20060280787A1 (en) * | 2005-06-14 | 2006-12-14 | Baxter International Inc. | Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof |
| WO2007059515A2 (en) * | 2005-11-15 | 2007-05-24 | Baxter International, Inc. | Compositions of lipoxygenase inhibitors |
| US20090152176A1 (en) * | 2006-12-23 | 2009-06-18 | Baxter International Inc. | Magnetic separation of fine particles from compositions |
| US20080293814A1 (en) * | 2007-05-22 | 2008-11-27 | Deepak Tiwari | Concentrate esmolol |
| US8426467B2 (en) * | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
| US8722736B2 (en) * | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
| US9394327B1 (en) * | 2013-03-15 | 2016-07-19 | The Trustees Of California State University | Nucleoside crystals, crystal nucleation and growth control with antifreeze proteins |
| BR112017010430A2 (pt) * | 2014-11-18 | 2017-12-26 | Pixarbio Corp | composição para tratar dor aguda, pós-operatória ou crônica em um indivíduo, método para tratar um indivíduo tendo dor aguda, pós-operatória ou crônica e kit para produzir a composição |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2861920A (en) * | 1954-05-04 | 1958-11-25 | Upjohn Co | Therapeutic suspensions of steroids containing pvp and/or pva |
| US4213963A (en) * | 1978-12-14 | 1980-07-22 | Janssen Pharmaceutica N.V. | Fluspirilene-containing compositions |
| US4431641A (en) * | 1980-10-17 | 1984-02-14 | Ciba-Geigy Corporation | Pharmaceutical compositions having antiepileptic and antineuralgic action |
| CH649080A5 (de) * | 1981-04-16 | 1985-04-30 | Ciba Geigy Ag | 5h-dibenz(b,f)azepin-5-carboxamide als mittel zur prophylaxe und behandlung von zerebraler leistungsinsuffizienz. |
| JPS59147374A (ja) * | 1983-02-10 | 1984-08-23 | Fuji Xerox Co Ltd | 電子写真複写機のブラシクリ−ニング方法 |
| DE3306250A1 (de) * | 1983-02-23 | 1984-08-23 | Basf Ag, 6700 Ludwigshafen | Sphaerische einkristalle fuer pharmazeutische zwecke |
| US4548990A (en) * | 1983-08-15 | 1985-10-22 | Ciba-Geigy Corporation | Crosslinked, porous polymers for controlled drug delivery |
| EP0200213B1 (en) * | 1985-05-02 | 1992-07-22 | Ciba-Geigy Ag | Hydrogels with increased organic solvent soluble active agent loading capacity, their preparation and the use thereof |
| CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
| JPH0641286B2 (ja) * | 1987-05-14 | 1994-06-01 | 信行 西井 | 自動包装装置 |
| US4964606A (en) * | 1989-10-26 | 1990-10-23 | Ncr Corporation | Overhead mount for a CRT |
-
1988
- 1988-04-28 IL IL86211A patent/IL86211A/xx unknown
- 1988-04-30 JP JP63105539A patent/JPH01131117A/ja active Pending
- 1988-05-02 DE DE88107021T patent/DE3884044D1/de not_active Expired - Fee Related
- 1988-05-02 DD DD88315309A patent/DD269784A5/de not_active IP Right Cessation
- 1988-05-02 EP EP88107021A patent/EP0289977B1/de not_active Expired - Lifetime
- 1988-05-02 MX MX1133988A patent/MX11339A/es unknown
- 1988-05-02 CA CA000565638A patent/CA1328219C/en not_active Expired - Fee Related
- 1988-05-02 FI FI882044A patent/FI882044A7/fi not_active Application Discontinuation
- 1988-05-02 AT AT88107021T patent/ATE94390T1/de not_active IP Right Cessation
- 1988-05-02 PT PT87381A patent/PT87381B/pt not_active IP Right Cessation
- 1988-05-02 ES ES88107021T patent/ES2043716T3/es not_active Expired - Lifetime
- 1988-05-03 HU HU882254A patent/HU199074B/hu not_active IP Right Cessation
- 1988-05-03 ZA ZA883135A patent/ZA883135B/xx unknown
- 1988-05-03 IE IE132888A patent/IE63081B1/en not_active IP Right Cessation
- 1988-05-03 NZ NZ224476A patent/NZ224476A/xx unknown
- 1988-05-03 DK DK238888A patent/DK169608B1/da not_active IP Right Cessation
- 1988-05-03 KR KR1019880005130A patent/KR960006059B1/ko not_active Expired - Lifetime
- 1988-05-03 NO NO881933A patent/NO881933L/no unknown
- 1988-05-04 PH PH36892A patent/PH24895A/en unknown
- 1988-05-04 AU AU15558/88A patent/AU619178B2/en not_active Ceased
-
1989
- 1989-12-14 US US07/453,103 patent/US5122543A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE881328L (en) | 1988-11-04 |
| US5122543A (en) | 1992-06-16 |
| FI882044L (fi) | 1988-11-05 |
| EP0289977B1 (de) | 1993-09-15 |
| NZ224476A (en) | 1990-09-26 |
| CA1328219C (en) | 1994-04-05 |
| FI882044A0 (fi) | 1988-05-02 |
| JPH01131117A (ja) | 1989-05-24 |
| HUT46847A (en) | 1988-12-28 |
| KR880013550A (ko) | 1988-12-21 |
| DE3884044D1 (de) | 1993-10-21 |
| DK238888D0 (da) | 1988-05-03 |
| PT87381B (pt) | 1992-08-31 |
| DK169608B1 (da) | 1994-12-27 |
| IE63081B1 (en) | 1995-03-22 |
| ZA883135B (en) | 1988-11-07 |
| IL86211A (en) | 1992-03-29 |
| AU1555888A (en) | 1988-11-10 |
| DK238888A (da) | 1988-11-05 |
| NO881933L (no) | 1988-11-07 |
| EP0289977A1 (de) | 1988-11-09 |
| FI882044A7 (fi) | 1988-11-05 |
| AU619178B2 (en) | 1992-01-23 |
| KR960006059B1 (ko) | 1996-05-08 |
| PH24895A (en) | 1990-12-26 |
| NO881933D0 (no) | 1988-05-03 |
| DD269784A5 (de) | 1989-07-12 |
| PT87381A (pt) | 1989-05-31 |
| MX11339A (es) | 1993-12-01 |
| HU199074B (en) | 1990-01-29 |
| IL86211A0 (en) | 1988-11-15 |
| ATE94390T1 (de) | 1993-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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