ES2051998T3 - Composiciones aumentadoras del flujo transdermal. - Google Patents

Composiciones aumentadoras del flujo transdermal.

Info

Publication number
ES2051998T3
ES2051998T3 ES89301896T ES89301896T ES2051998T3 ES 2051998 T3 ES2051998 T3 ES 2051998T3 ES 89301896 T ES89301896 T ES 89301896T ES 89301896 T ES89301896 T ES 89301896T ES 2051998 T3 ES2051998 T3 ES 2051998T3
Authority
ES
Spain
Prior art keywords
transdermic
xey
penetra
animals
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89301896T
Other languages
English (en)
Inventor
Russell Owen Potts
Michael Lee Francoeur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Application granted granted Critical
Publication of ES2051998T3 publication Critical patent/ES2051998T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSICION FARMACEUTICA PARA MEJORAR EL FLUJO TRANSDERMICO, PARA ADMINISTRACION POR VIA TRANSDERMICA A HOMBRES O ANIMALES INFERIORES; QUE COMPRENDE UNA CANTIDAD SEGURA Y EFECTIVA DE UN COMPUESTO FARMACOLOGICAMENTE ACTIVO O UN PROFARMACO SUYO, UN SISTEMA DISOLVENTE ACUOSO QUE COMPRENDE DE 15 A 75% EN VOLUMEN DE UNO O MAS DISOLVENTES MISCIBLES CON AGUA Y UN MEJORADOR DE LA PENETRACION SELECCIONADO DE CIERTAS 1 - ALQUILAZACICLOHEPTAN - 2 - ONAS Y COMPUESTOS CIS OLEFINICOS DE FORMULA CH3(CH2)XCH = CH(CH2)YR3 (DONDE R3 ES CH2OH, CH2NH2 O COR4 Y R4 ES OH O ALCOXI DE 1 A 4 C, X E Y SON CADA UNO UN ENTERO DE 3 A 13 Y LA SUMA DE X E Y VALES DE 10 A 16). LA INVENCION INCLUYE TAMBIEN METODOS PARA SU EMPLEO EN EL TRATAMIENTO DE VARIAS ENFERMEDADES EN HOMBRES Y ANIMALES, POR ADMINISTRACION TRANSDERMICA DE DICHA COMPOSICION.
ES89301896T 1988-02-29 1989-02-24 Composiciones aumentadoras del flujo transdermal. Expired - Lifetime ES2051998T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16192688A 1988-02-29 1988-02-29

Publications (1)

Publication Number Publication Date
ES2051998T3 true ES2051998T3 (es) 1994-07-01

Family

ID=22583397

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89301896T Expired - Lifetime ES2051998T3 (es) 1988-02-29 1989-02-24 Composiciones aumentadoras del flujo transdermal.

Country Status (11)

Country Link
EP (1) EP0331382B1 (es)
JP (1) JPH0768147B2 (es)
AT (1) ATE80313T1 (es)
CA (1) CA1331137C (es)
DE (1) DE68902753T2 (es)
DK (1) DK93289A (es)
ES (1) ES2051998T3 (es)
FI (1) FI92650C (es)
GR (1) GR3005657T3 (es)
IE (1) IE61946B1 (es)
PT (1) PT89837B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0425443A1 (de) * 1989-10-27 1991-05-02 Ciba-Geigy Ag Injizierbares parasitizides Mittel
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
ATE95421T1 (de) * 1990-04-26 1993-10-15 Sagitta Arzneimittel Gmbh Piroxicam enthaltende pharmazeutische zusammensetzung zur topischen anwendung.
JPH06510020A (ja) * 1991-03-29 1994-11-10 ユニバーシティ・オブ・フロリダ 混成リン酸エステル誘導体を経た標的への薬剤供給
US5496819A (en) * 1991-11-15 1996-03-05 Ss Pharmaceutical Co., Ltd. Antiphlogistic-analgesic plaster comprising triacetin and piroxicam
DE69330388T2 (de) * 1992-12-31 2002-01-03 Sunkyong Industries Co. Ltd., Suwon Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam
DE4341572C1 (de) * 1993-12-07 1995-06-22 Univ Dresden Tech Zahnriemengetriebe
GB9404248D0 (en) * 1994-03-05 1994-04-20 Boots Co Plc Pharmaceutical formulations
US6106856A (en) * 1994-03-09 2000-08-22 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Transdermal delivery of calcium channel blockers, such as nifedipine
UA48212C2 (uk) 1996-01-31 2002-08-15 Сергей Дмітрієвіч БУРЛАКОВ Антиглюкокортикоїдний лікарський засіб
HUP0001739A3 (en) * 1997-03-31 2001-04-28 Johnson & Johnson Consumer Solvent system for enhanced penetration of pharmaceutical compounds for topical use and the use of the buffer solvent system
CA2309688C (en) * 1997-11-10 2007-04-24 Cellegy Pharmaceuticals, Inc. Penetration enhancing and irritation reducing systems
JP4626202B2 (ja) * 2003-07-16 2011-02-02 大正製薬株式会社 ピロキシカム含有外用消炎鎮痛剤組成物
JP2006188500A (ja) * 2004-12-08 2006-07-20 Toyama Chem Co Ltd ピロキシカムを含有する外用液剤
CA2728727C (en) * 2008-06-24 2018-01-23 Intervet International B.V. Pharmaceutical transdermal compositions and method for treating inflammation in cattle
GB0906868D0 (en) * 2009-04-21 2009-06-03 Rabin Bennie Amlodipine salt compositions
EP3801460B1 (en) * 2018-06-01 2025-03-12 Tavanta Therapeutics Hungary Incorporated Topical amlodipine salts for the treatment of anorectal diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2314731A1 (fr) * 1975-06-19 1977-01-14 Nelson Res & Dev Azacycloalcan-2-ones 1-substituees et compositions pharmaceutiques contenant ces composes a titre d'excipients
CA1165240A (en) * 1980-07-09 1984-04-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
JPS59216818A (ja) * 1983-05-26 1984-12-06 Takeda Chem Ind Ltd 経皮吸収外用製剤
JPS60199834A (ja) * 1984-03-23 1985-10-09 Takeda Chem Ind Ltd 経皮吸収外用製剤
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
MY102980A (en) * 1986-10-31 1993-03-31 Pfizer Transdermal flux enhancing compositions

Also Published As

Publication number Publication date
FI92650C (fi) 1994-12-27
JPH0768147B2 (ja) 1995-07-26
DE68902753T2 (de) 1993-01-21
CA1331137C (en) 1994-08-02
IE61946B1 (en) 1994-11-30
EP0331382A2 (en) 1989-09-06
PT89837A (pt) 1989-10-04
EP0331382A3 (en) 1990-05-30
DK93289A (da) 1989-08-30
ATE80313T1 (de) 1992-09-15
JPH023613A (ja) 1990-01-09
PT89837B (pt) 1994-01-31
IE890642L (en) 1989-08-29
GR3005657T3 (es) 1993-06-07
FI890930A7 (fi) 1989-08-30
FI890930A0 (fi) 1989-02-27
EP0331382B1 (en) 1992-09-09
DK93289D0 (da) 1989-02-27
FI92650B (fi) 1994-09-15
DE68902753D1 (de) 1992-10-15

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