ES2053415T3 - Substancias con estructura tipo heparina y su metodo de produccion. - Google Patents

Substancias con estructura tipo heparina y su metodo de produccion.

Info

Publication number
ES2053415T3
ES2053415T3 ES90115227T ES90115227T ES2053415T3 ES 2053415 T3 ES2053415 T3 ES 2053415T3 ES 90115227 T ES90115227 T ES 90115227T ES 90115227 T ES90115227 T ES 90115227T ES 2053415 T3 ES2053415 T3 ES 2053415T3
Authority
ES
Spain
Prior art keywords
heparine
substances
production method
type structure
antiromobitic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90115227T
Other languages
English (en)
Other versions
ES2053415T1 (es
Inventor
Fernando Fussi
Victor Diaz
Ricardo Domanico
Esteban Fuentes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajorca SA
Original Assignee
Ajorca SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajorca SA filed Critical Ajorca SA
Publication of ES2053415T1 publication Critical patent/ES2053415T1/es
Application granted granted Critical
Publication of ES2053415T3 publication Critical patent/ES2053415T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PROCESO PARA LA SINTESIS DE UN NUEVO DERIVADO N-ACETILADO DE HEPARINA, POR REACCION DE UNA HEPARINA N-DESULFATADA CON ANHIDRIDO ACETICO, NUEVO COMPUESTO ASI OBTENIDO Y COMPOSICIONES FARMACEUTICAS CONTENIENDOLO, TERMINADAS CON PROPIEDADES ANTITROMBOTICAS Y FIBRINOLITICAS CON REDUCIDA ACTIVIDAD ANTICOAGULANTE.
ES90115227T 1989-08-18 1990-08-08 Substancias con estructura tipo heparina y su metodo de produccion. Expired - Lifetime ES2053415T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AR89314703A AR245455A1 (es) 1989-08-18 1989-08-18 Procedimiento para la obtencion de derivados de heparina,parcial o totalmente n-acetilados en el resto glucosaminico y productos asi obtenidos excluidos sus usos farmaceuticos.

Publications (2)

Publication Number Publication Date
ES2053415T1 ES2053415T1 (es) 1994-08-01
ES2053415T3 true ES2053415T3 (es) 1995-05-16

Family

ID=3478715

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90115227T Expired - Lifetime ES2053415T3 (es) 1989-08-18 1990-08-08 Substancias con estructura tipo heparina y su metodo de produccion.

Country Status (7)

Country Link
EP (1) EP0413248B1 (es)
JP (1) JPH03185001A (es)
KR (1) KR0155166B1 (es)
AR (1) AR245455A1 (es)
AT (1) ATE117321T1 (es)
DE (2) DE69016127T2 (es)
ES (1) ES2053415T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696100A (en) * 1992-12-22 1997-12-09 Glycomed Incorporated Method for controlling O-desulfation of heparin and compositions produced thereby
US5296471A (en) * 1992-12-22 1994-03-22 Glycomed Incorporated Method for controlling o-desulfation of heparin and compositions produced thereby
JP3929486B2 (ja) * 1994-07-01 2007-06-13 生化学工業株式会社 脱硫酸化多糖の製造法及び脱硫酸化ヘパリン
DK1435877T3 (da) 2001-10-15 2009-08-03 Hemoteq Ag Overtrækning af stents for at forhindre restenose

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1169888B (it) * 1983-10-25 1987-06-03 Italfarmaco Spa Glicosaminoglicani modificati dotati di attivita' antitrombotica
DE3422518A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
AU7852687A (en) * 1986-08-21 1988-03-08 University Of Texas System, The Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion

Also Published As

Publication number Publication date
KR910004668A (ko) 1991-03-29
DE69016127T2 (de) 1995-05-18
AR245455A1 (es) 1994-01-31
JPH03185001A (ja) 1991-08-13
KR0155166B1 (ko) 1998-10-15
ATE117321T1 (de) 1995-02-15
EP0413248A1 (en) 1991-02-20
DE413248T1 (de) 1993-06-09
EP0413248B1 (en) 1995-01-18
DE69016127D1 (de) 1995-03-02
ES2053415T1 (es) 1994-08-01

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