ES2054667T3 - Anticuerpos monoclonales contra c5a y des-arg74-c5a, su produccion y uso. - Google Patents

Anticuerpos monoclonales contra c5a y des-arg74-c5a, su produccion y uso.

Info

Publication number
ES2054667T3
ES2054667T3 ES87303762T ES87303762T ES2054667T3 ES 2054667 T3 ES2054667 T3 ES 2054667T3 ES 87303762 T ES87303762 T ES 87303762T ES 87303762 T ES87303762 T ES 87303762T ES 2054667 T3 ES2054667 T3 ES 2054667T3
Authority
ES
Spain
Prior art keywords
arg74
des
monoclonal antibodies
production
antibodies against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87303762T
Other languages
English (en)
Inventor
James W Larrick
Brian M Fendly
Tracey E Deinhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cetus Oncology Corp
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Application granted granted Critical
Publication of ES2054667T3 publication Critical patent/ES2054667T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE PRODUCEN ANTICUERPOS MONOCLONALES QUE SE CARACTERIZA POR SU APTITUD PARA COMBINARSE CON EL COMPONENTE DEL COMPLEMENTO HUMANO C5A. ESTOS ANTICUERPOS SON PARTICULARMENTE UTILES PARA EL TRATAMIENTO DE ESTADOS ASOCIADOS CON LA ACTIVACION DEL COMPLEMENTO INTRAVASCULAR NOCIVA O CAUSADOS POR ELLA. ADEMAS, ESTOS ANTICUERPOS PUEDEN UTILIZARSE EN UN METODO INMUNOLOGICO O DE INMUNODIAGNOSTICO PARA DETECTAR C5A O DES-ARG74-C5A EN HUMANOS EN FLUIDOS.
ES87303762T 1986-04-28 1987-04-28 Anticuerpos monoclonales contra c5a y des-arg74-c5a, su produccion y uso. Expired - Lifetime ES2054667T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85678086A 1986-04-28 1986-04-28
US94783986A 1986-12-30 1986-12-30

Publications (1)

Publication Number Publication Date
ES2054667T3 true ES2054667T3 (es) 1994-08-16

Family

ID=27127377

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87303762T Expired - Lifetime ES2054667T3 (es) 1986-04-28 1987-04-28 Anticuerpos monoclonales contra c5a y des-arg74-c5a, su produccion y uso.

Country Status (4)

Country Link
EP (1) EP0245993B1 (es)
JP (2) JP2703764B2 (es)
DE (1) DE3785967T2 (es)
ES (1) ES2054667T3 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO162210C (no) * 1987-07-20 1989-11-22 Fasting Biotech As Monoklonale antistoffer mot c5a for in-vitro anvendelse ved immunologiske kvantitative teknikker eller ved isolering av c5a.
DE3924924A1 (de) * 1989-07-27 1991-02-07 Goetze Otto Verfahren zum nachweis und/oder der quantitativen bestimmung von komplementpeptid c5a und/oder c5adesarg
US5837499A (en) * 1993-12-06 1998-11-17 Ciba-Geigy Corporation DNA encoding C5A receptor antagonists having substantially no agonist activity and methods of expressing same
US5807824A (en) * 1993-12-06 1998-09-15 Ciba-Geigy Corporation C5A receptor antagonists having substantially no agonist activity
WO1995016033A1 (en) * 1993-12-06 1995-06-15 Ciba-Geigy Ag C5a RECEPTOR ANTAGONISTS HAVING SUBSTANTIALLY NO AGONIST ACTIVITY
DE69534701T2 (de) 1994-09-23 2006-10-19 Alexion Pharmaceuticals, Inc., Cheshire Verfahren zur behandlung von entzündlichen gelenkerkrankungen
US6673346B1 (en) 1999-08-31 2004-01-06 The Regents Of The University Of Michigan Compositions and methods for the treatment of sepsis
ES2283594T5 (es) 2001-08-17 2016-03-15 Genentech, Inc. Inhibidores de la ruta del complemento que se unen a C5 y C5a sin impedir la formación de C5b
WO2004043223A2 (en) * 2002-11-05 2004-05-27 The Regents Of The University Of Michigan Compositions and methods for the diagnosis and treatment of sepsis
EP2266606B1 (en) * 2003-05-15 2014-09-10 Genentech, Inc. Methods and compositions for the prevention and treatment of sepsis
MX340696B (es) 2010-04-30 2016-07-21 Alexion Pharma Inc Anticuerpos anti-c5a y metodos para usar los anticuerpos.
EP2468295A1 (en) 2010-12-21 2012-06-27 Affiris AG Vaccines based on peptides of the complement protein C5a
EP2666785A1 (en) 2012-05-23 2013-11-27 Affiris AG Complement component C5a-based vaccine
SG11201601044XA (en) 2013-08-12 2016-03-30 Genentech Inc Compositions and method for treating complement-associated conditions
NZ631007A (en) * 2014-03-07 2015-10-30 Alexion Pharma Inc Anti-c5 antibodies having improved pharmacokinetics
AU2015253042A1 (en) 2014-05-01 2016-10-20 Genentech, Inc. Anti-factor D antibody variants and uses thereof
US10407510B2 (en) 2015-10-30 2019-09-10 Genentech, Inc. Anti-factor D antibodies and conjugates
EP3368090A1 (en) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Anti-factor d antibody variant conjugates and uses thereof
JP6923212B2 (ja) * 2016-02-17 2021-08-18 国立大学法人 東京医科歯科大学 動脈硬化性疾患の発症の予測因子および検査方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0776240B2 (ja) * 1983-05-06 1995-08-16 ベロス グル−プ エンドトキシンコア−と反応性のモノクロ−ナル抗体

Also Published As

Publication number Publication date
JPS62269699A (ja) 1987-11-24
JP2703764B2 (ja) 1998-01-26
EP0245993A3 (en) 1989-07-26
DE3785967T2 (de) 1993-12-02
DE3785967D1 (de) 1993-07-01
EP0245993B1 (en) 1993-05-26
EP0245993A2 (en) 1987-11-19
JP2820402B2 (ja) 1998-11-05
JPH10130167A (ja) 1998-05-19

Similar Documents

Publication Publication Date Title
ES2054667T3 (es) Anticuerpos monoclonales contra c5a y des-arg74-c5a, su produccion y uso.
NL7806452A (nl) Werkwijze voor de behandeling van aromatische polya- midevezels, die geschikt zijn voor gebruik in construc- tiematerialen en rubbers, alsmede aldus behandelde vezels en met deze vezels gewapende gevormde voort- brengsels.
DE69128543D1 (de) Monoklonale antikörper der maus
BG101024A (bg) Моноклонално антитяло срещу сd44v6
DE68900371D1 (de) Textile struktur zur herstellung von schichtstoffen und schichtformteile, die diese struktur enthalten.
NO873495L (no) Monoklonale antistoffer og peptider som kan anvendes til behandling og diagnose av hiv-infeksjoner.
NL7703010A (nl) Werkwijze voor het vervaardigen van gewelfd glas en gewelfd glas, verkregen door toepassing van genoemde werkwijze.
AT265991B (de) Verfahren und Vorrichtung zur Herstellung von Gemischen, Lösungen, Emulsionen, Suspensionen u.dgl. sowie zur biologischen Reinigung von freien Gewässern
ES2062809T3 (es) Proteinas bacterianas del estres.
MX9203629A (es) Composiciones de anticuerpos monoclonales para el tratamiento profilactico o terapeutico de infecciones bacterianas debidas a estreptococos del grupo b.
FR2491334B1 (es)
CL2023003331A1 (es) Anticuerpos anti-tmprs66 y usos de los mismos.
DE69426767D1 (de) Anti idiotypische Antikörper gegen Gonococcen und diese verwendende Verfahren und Zusammensetzungen.
IT1044555B (it) Benzodipironi e procedimento per prepararli
SE7608174L (sv) Forfarande for framstellning av antiserum
CH417772A (de) Halbleitergerät, Verfahren zur Herstellung dieses Halbleitergerätes und Verwendung desselben
NO890046D0 (no) Disubstituerte pyridiner.
ES2059418T3 (es) Antigeno asociado a carcinoma humano y anticuerpo asociado al antigeno.
DE3585049D1 (de) Monoklonale antikoerper.
ATE45562T1 (de) Glasgefaess, insbesondere ampulle, und verfahren zur behandlung dieses glasgefaesses.
FI844645L (fi) 1,7-difenyl-3-metylaza-7-cyan-8 -metyl-nonan foer anvaendning vid bekaempning av sjukdomar.
FI92716C (fi) Uudet monoklonaaliset vasta-aineet IFN-omegalle, niiden valmistusmenetelmät ja niiden käyttö IFN-omegan puhdistamiseen ja osoittamiseen
DE59006307D1 (de) Badezusatz und dessen Verwendung.
CH469267A (de) Reagenz zur Bestimmung von menschlichem Chorion-Gonadotropin, Verfahren zur Herstellung des Reagenz und dessen Verwendung
DE69114707D1 (de) Neue alpha-glukosidaseinhibitoren.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 245993

Country of ref document: ES