ES2059418T3 - Antigeno asociado a carcinoma humano y anticuerpo asociado al antigeno. - Google Patents

Antigeno asociado a carcinoma humano y anticuerpo asociado al antigeno.

Info

Publication number
ES2059418T3
ES2059418T3 ES88105299T ES88105299T ES2059418T3 ES 2059418 T3 ES2059418 T3 ES 2059418T3 ES 88105299 T ES88105299 T ES 88105299T ES 88105299 T ES88105299 T ES 88105299T ES 2059418 T3 ES2059418 T3 ES 2059418T3
Authority
ES
Spain
Prior art keywords
antigen
human carcinoma
antibody
human
diagnostic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88105299T
Other languages
English (en)
Inventor
Jens Christian Jensenius
Per Borup-Christensen
Karin Erb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BORUP CHRISTENSEN PER
Original Assignee
BORUP CHRISTENSEN PER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BORUP CHRISTENSEN PER filed Critical BORUP CHRISTENSEN PER
Application granted granted Critical
Publication of ES2059418T3 publication Critical patent/ES2059418T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN ANTIGENO ASOCIADO CON CARCINOMA HUMANO QUE TIENE UN PESO MOLECULAR APARENTE DE 43000 Y UN PUNTO ISOELECTRICO EN EL INTERVALO DE 5,4-6,2 Y QUE TIENE AL MENOS UN EPITOPE QUE ES REACTIVO CON UN ANTICUERPO MONOCLONAL PRODUCIDO POR LA LINEA CELULAR DE HIBRIDOMA HUMANO B9165 (ECACC 87040201), O UN ANALOGO SUYO, PUEDE USARSE COO AGENTE DE DIAGNOSTICO O TERAPEUTICO, ES DECIR PARA LA DIAGNOSIS O TRATAMIENTO DE CARCINOMA HUMANO. UN ANTICUERPO SURGIDO CONTRA EL ANTIGENO PUEDE MPLEARSE PARA FINES DE DIAGNOSTICO O TERAPEUTICOS.
ES88105299T 1987-04-03 1988-03-31 Antigeno asociado a carcinoma humano y anticuerpo asociado al antigeno. Expired - Lifetime ES2059418T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK169987A DK169987D0 (da) 1987-04-03 1987-04-03 Human tumor-associated antigen, ca-ou1

Publications (1)

Publication Number Publication Date
ES2059418T3 true ES2059418T3 (es) 1994-11-16

Family

ID=8107312

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88105299T Expired - Lifetime ES2059418T3 (es) 1987-04-03 1988-03-31 Antigeno asociado a carcinoma humano y anticuerpo asociado al antigeno.

Country Status (14)

Country Link
US (1) US5338661A (es)
EP (1) EP0285173B1 (es)
JP (1) JPH082920B2 (es)
KR (1) KR890700358A (es)
AU (1) AU618260B2 (es)
DE (1) DE3884646T2 (es)
DK (1) DK169987D0 (es)
ES (1) ES2059418T3 (es)
FI (1) FI894650A7 (es)
IE (1) IE60993B1 (es)
IL (1) IL85955A (es)
NZ (1) NZ224156A (es)
WO (1) WO1988007377A1 (es)
ZA (1) ZA882353B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU619226B2 (en) * 1987-09-28 1992-01-23 Children's Hospital Medical Center Human cell lines of epithelial lung adenocarcinoma origin, human proteins and methods
US5118611A (en) * 1988-07-25 1992-06-02 Adeza Biomedical Corporation Adenocarcinoma antigen binding methods and reagents
CA2015862A1 (en) * 1989-05-04 1990-11-04 Gajanan Nilaver Cell surface antigen that binds with l6 monoclonal antibody
WO1993015405A1 (en) 1992-01-29 1993-08-05 Sci-Clone, Inc. Carcinoma associated antigen (sk1) monoclonal antibodies against sk1, methods of producing these antibodies and use therfor
US5834215A (en) * 1994-10-05 1998-11-10 The Administrators Of The Tulane Educational Fund Method for detecting antipolymer antibodies and diagnosing silicone related disease (SRD) fibromyalgia and chronic fatigue syndrome (CFS)
US5744585A (en) * 1995-03-16 1998-04-28 Medenica; Rajko D. Human monoclonal antibody against lung carcinoma
US6288215B1 (en) 1996-08-30 2001-09-11 Auburn University Monoclonal antibodies specific to cooked meats
AU4094297A (en) * 1996-08-30 1998-03-19 Auburn University Monoclonal antibodies specific to cooked meats
US20020127584A1 (en) * 1997-09-18 2002-09-12 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP4406206B2 (ja) * 2001-04-24 2010-01-27 バイエル コーポレーション ヒトｔｉｍｐ−１抗体
AU2002327704A1 (en) * 2001-09-21 2003-04-01 Raven Biotechnologies, Inc. Antibodies that bind to cancer-associated antigen cytokeratin 8 and methods of use thereof
AU2003207459A1 (en) * 2002-01-03 2003-07-24 The Scripps Research Institute Cancer-associated epitope

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468457A (en) * 1981-06-01 1984-08-28 David M. Goldenberg Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
US4579827A (en) * 1983-03-11 1986-04-01 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies
NZ210867A (en) * 1984-01-31 1989-01-06 Litton Bionetics Inc Tumour-specific monoclonal antibodies, production thereof and use
GR850552B (es) * 1984-03-07 1985-07-05 Du Pont
US4761377A (en) * 1984-10-15 1988-08-02 The Regents Of The University Of California Human-human hybrid cell lines that produce antibodies against antigenic determinants on cancer cells
DK172686A (da) * 1985-04-22 1986-10-23 Hybritech Inc Antigen opnaaet ud fra humant vaev, fremgangsmaade til under anvendelse af antigenet at fremstille monoklonale antistoffer til diagnose og behandling af cancer, fremgangsmaade til paavisning af cancer, samt antistoffer mod antigenet
ES8800604A1 (es) * 1985-04-22 1987-11-16 Hybritech Inc Un metodo para producir anticuerpos monoclonales
EP0242154B1 (en) * 1986-04-17 1993-03-03 Hybritech Incorporated A novel tumor-associated antigen

Also Published As

Publication number Publication date
JPH02503383A (ja) 1990-10-18
EP0285173B1 (en) 1993-10-06
ZA882353B (en) 1988-09-23
DE3884646D1 (de) 1993-11-11
DE3884646T2 (de) 1994-01-27
IL85955A0 (en) 1988-09-30
KR890700358A (ko) 1989-04-24
FI894650L (fi) 1989-10-02
IE880976L (en) 1988-10-03
NZ224156A (en) 1991-07-26
EP0285173A2 (en) 1988-10-05
US5338661A (en) 1994-08-16
DK169987D0 (da) 1987-04-03
IL85955A (en) 1994-12-29
AU618260B2 (en) 1991-12-19
FI894650A0 (fi) 1989-10-02
FI894650A7 (fi) 1989-10-02
WO1988007377A1 (en) 1988-10-06
EP0285173A3 (en) 1990-01-31
JPH082920B2 (ja) 1996-01-17
IE60993B1 (en) 1994-09-07
AU1596588A (en) 1988-11-02

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