ES2055416T3 - Derivados de fenilsulfona. - Google Patents

Derivados de fenilsulfona.

Info

Publication number
ES2055416T3
ES2055416T3 ES90902305T ES90902305T ES2055416T3 ES 2055416 T3 ES2055416 T3 ES 2055416T3 ES 90902305 T ES90902305 T ES 90902305T ES 90902305 T ES90902305 T ES 90902305T ES 2055416 T3 ES2055416 T3 ES 2055416T3
Authority
ES
Spain
Prior art keywords
derivatives
fenilsulfona
derivative
aminophenyl
new derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90902305T
Other languages
English (en)
Inventor
David Robert Brittain
Steven Paul Galdwill Bun Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Linda Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/306,676 external-priority patent/US5153227A/en
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of ES2055416T3 publication Critical patent/ES2055416T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

EL INVENTO DESCUBRE UN NUEVO DERIVADO DE LA AMINOFENILSULFONA (Y SUS SALES) QUE ES UN INHIBIDOR DE LA ENZIMA ALDOSA REDUCTASA; LAS COMPOSICIONES FARMACEUTICAS QUE CONTIENEN EL NUEVO DERIVADO, Y LOS PROCESOS PARA SU MANUFACTURACION. EL INVENTO TAMBIEN DESCUBRE CIERTOS DERIVADOS N-ACIL DEL DERIVADO DE LA AMINOFENILSULFONA, QUE SON UTILES EN LA PRODUCCION DE OTROS DERIVADOS.
ES90902305T 1989-02-06 1990-02-02 Derivados de fenilsulfona. Expired - Lifetime ES2055416T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/306,676 US5153227A (en) 1987-08-06 1989-02-06 Phenylsulfonyl nitromethanes as aldose reductase inhibitors

Publications (1)

Publication Number Publication Date
ES2055416T3 true ES2055416T3 (es) 1994-08-16

Family

ID=23186342

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90902305T Expired - Lifetime ES2055416T3 (es) 1989-02-06 1990-02-02 Derivados de fenilsulfona.

Country Status (21)

Country Link
EP (1) EP0408713B1 (es)
JP (1) JP3056245B2 (es)
KR (1) KR910700232A (es)
AT (1) ATE89550T1 (es)
AU (1) AU630151B2 (es)
CA (1) CA2026003A1 (es)
DE (1) DE69001650T2 (es)
DK (1) DK0408713T3 (es)
ES (1) ES2055416T3 (es)
FI (1) FI904891A7 (es)
GB (1) GB2227745B (es)
GR (1) GR1000423B (es)
HU (1) HU206674B (es)
IE (1) IE63463B1 (es)
IL (1) IL93225A (es)
NO (1) NO173822C (es)
NZ (1) NZ232293A (es)
PT (1) PT93064B (es)
RU (2) RU1817776C (es)
WO (1) WO1990008761A1 (es)
ZA (1) ZA90674B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
NZ503796A (en) * 1997-10-20 2001-11-30 Dainippon Pharmaceutical Co Fast-dissolving pharmaceutical composition comprising micronised (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (AS-3201)
DK0974356T3 (da) * 1998-07-15 2003-10-27 Merck Sante Sas Tabletter omfattende en kombination af metformin og glibenclamid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
DE3727468A1 (de) * 1987-08-18 1989-03-02 Kolbenschmidt Ag Verbundgleitlager

Also Published As

Publication number Publication date
ATE89550T1 (de) 1993-06-15
HU206674B (en) 1992-12-28
IL93225A (en) 1994-05-30
NZ232293A (en) 1992-06-25
GB9002373D0 (en) 1990-04-04
JP3056245B2 (ja) 2000-06-26
GB2227745A (en) 1990-08-08
RU2034834C1 (ru) 1995-05-10
PT93064B (pt) 1995-12-29
WO1990008761A1 (en) 1990-08-09
DK0408713T3 (da) 1993-06-14
DE69001650D1 (de) 1993-06-24
AU630151B2 (en) 1992-10-22
NO904335L (no) 1990-12-05
EP0408713B1 (en) 1993-05-19
JPH03505215A (ja) 1991-11-14
PT93064A (pt) 1990-08-31
AU4953890A (en) 1990-08-24
IE900288L (en) 1990-08-06
HUT55354A (en) 1991-05-28
NO173822B (no) 1993-11-01
IL93225A0 (en) 1990-11-05
HU901209D0 (en) 1991-03-28
GR900100069A (en) 1991-06-28
GR1000423B (el) 1992-07-30
RU1817776C (ru) 1993-05-23
ZA90674B (en) 1990-10-31
GB2227745B (en) 1992-08-05
EP0408713A1 (en) 1991-01-23
FI904891L (fi) 1991-08-07
FI904891A0 (fi) 1990-10-04
FI904891A7 (fi) 1991-08-07
CA2026003A1 (en) 1990-08-07
DE69001650T2 (de) 1993-09-02
KR910700232A (ko) 1991-03-14
NO904335D0 (no) 1990-10-05
NO173822C (no) 1994-02-09
IE63463B1 (en) 1995-04-19

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