GR1000423B - Μεθοδος παρασκευης παραγωγων φαινυλοσουλφονης. - Google Patents

Μεθοδος παρασκευης παραγωγων φαινυλοσουλφονης.

Info

Publication number
GR1000423B
GR1000423B GR900100069A GR900100069A GR1000423B GR 1000423 B GR1000423 B GR 1000423B GR 900100069 A GR900100069 A GR 900100069A GR 900100069 A GR900100069 A GR 900100069A GR 1000423 B GR1000423 B GR 1000423B
Authority
GR
Greece
Prior art keywords
derivatives
derivative
phenylosulphone
producing
new
Prior art date
Application number
GR900100069A
Other languages
English (en)
Other versions
GR900100069A (en
Inventor
David Robert Brittain
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Linda Slater
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/306,676 external-priority patent/US5153227A/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of GR900100069A publication Critical patent/GR900100069A/el
Publication of GR1000423B publication Critical patent/GR1000423B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Η ευρεσιτεχνία περιγράφει νέο παράγωγο αμινοφαινυλοσουλφόνης (και τα άλατά της) το οποίο είναι αναστολέας του ενζύμου αναγωγάση αλδόζης, φαρμακευτικές συνθέσεις οι οποίες περιέχουν το νέο παράγωγο και μεθόδους παρασκευής του. Η ευρεσιτεχνία, επίσης, περιγράφει ωρισμένα νέα Ν-ακυλο- παράγωγα του παραγώγου της αμινοφαινυλοσουλφόνης, τα οποία είναι χρήσιμα για την παρασκευή του τελευταίου αυτού παραγώγου. ω
GR900100069A 1989-02-06 1990-02-05 Μεθοδος παρασκευης παραγωγων φαινυλοσουλφονης. GR1000423B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/306,676 US5153227A (en) 1987-08-06 1989-02-06 Phenylsulfonyl nitromethanes as aldose reductase inhibitors

Publications (2)

Publication Number Publication Date
GR900100069A GR900100069A (en) 1991-06-28
GR1000423B true GR1000423B (el) 1992-07-30

Family

ID=23186342

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100069A GR1000423B (el) 1989-02-06 1990-02-05 Μεθοδος παρασκευης παραγωγων φαινυλοσουλφονης.

Country Status (21)

Country Link
EP (1) EP0408713B1 (el)
JP (1) JP3056245B2 (el)
KR (1) KR910700232A (el)
AT (1) ATE89550T1 (el)
AU (1) AU630151B2 (el)
CA (1) CA2026003A1 (el)
DE (1) DE69001650T2 (el)
DK (1) DK0408713T3 (el)
ES (1) ES2055416T3 (el)
FI (1) FI904891L (el)
GB (1) GB2227745B (el)
GR (1) GR1000423B (el)
HU (1) HU206674B (el)
IE (1) IE63463B1 (el)
IL (1) IL93225A (el)
NO (1) NO173822C (el)
NZ (1) NZ232293A (el)
PT (1) PT93064B (el)
RU (2) RU1817776C (el)
WO (1) WO1990008761A1 (el)
ZA (1) ZA90674B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
CZ299018B6 (cs) * 1997-10-20 2008-04-02 Dainippon Sumitomo Pharma Co., Ltd. Rychlerozpustný farmaceutický prípravek
DE69818444T2 (de) * 1998-07-15 2004-05-06 Merck Santé Tabletten enthaltend eine Kombination von Glibenclamid und Metformin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
DE3727468A1 (de) * 1987-08-18 1989-03-02 Kolbenschmidt Ag Verbundgleitlager

Also Published As

Publication number Publication date
HUT55354A (en) 1991-05-28
PT93064B (pt) 1995-12-29
IE63463B1 (en) 1995-04-19
GB2227745A (en) 1990-08-08
FI904891A7 (fi) 1991-08-07
JP3056245B2 (ja) 2000-06-26
RU2034834C1 (ru) 1995-05-10
NO173822B (no) 1993-11-01
NO904335D0 (no) 1990-10-05
WO1990008761A1 (en) 1990-08-09
DE69001650T2 (de) 1993-09-02
GB9002373D0 (en) 1990-04-04
EP0408713B1 (en) 1993-05-19
NZ232293A (en) 1992-06-25
FI904891A0 (fi) 1990-10-04
NO904335L (no) 1990-12-05
GR900100069A (en) 1991-06-28
HU206674B (en) 1992-12-28
NO173822C (no) 1994-02-09
PT93064A (pt) 1990-08-31
AU630151B2 (en) 1992-10-22
ATE89550T1 (de) 1993-06-15
CA2026003A1 (en) 1990-08-07
IL93225A (en) 1994-05-30
ZA90674B (en) 1990-10-31
EP0408713A1 (en) 1991-01-23
RU1817776C (ru) 1993-05-23
GB2227745B (en) 1992-08-05
DE69001650D1 (de) 1993-06-24
JPH03505215A (ja) 1991-11-14
IE900288L (en) 1990-08-06
FI904891L (fi) 1991-08-07
IL93225A0 (en) 1990-11-05
KR910700232A (ko) 1991-03-14
DK0408713T3 (da) 1993-06-14
ES2055416T3 (es) 1994-08-16
AU4953890A (en) 1990-08-24
HU901209D0 (en) 1991-03-28

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