ES2056383T3 - Eteres ciclicos de diarileter. - Google Patents

Eteres ciclicos de diarileter.

Info

Publication number
ES2056383T3
ES2056383T3 ES90306763T ES90306763T ES2056383T3 ES 2056383 T3 ES2056383 T3 ES 2056383T3 ES 90306763 T ES90306763 T ES 90306763T ES 90306763 T ES90306763 T ES 90306763T ES 2056383 T3 ES2056383 T3 ES 2056383T3
Authority
ES
Spain
Prior art keywords
diarileter
cyclic ethers
sulfinil
rent
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90306763T
Other languages
English (en)
Inventor
Philip Neil Edwards
Thomad Geoffrey Colerick Bird
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Imperial Chemical Industries Ltd
Original Assignee
ICI Pharma SA
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Pharma SA, Imperial Chemical Industries Ltd filed Critical ICI Pharma SA
Application granted granted Critical
Publication of ES2056383T3 publication Critical patent/ES2056383T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Epoxy Resins (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

EL INVENTO SE REFIERE A LA FORMULA I O A LAS SALES FARMACEUTICAMENTE ACEPTABLES DERIVADAS DE ELLAS FIG EN DONDE AR1 ES FENIL O NAFTIL OPCIONALMENTE SUSTITUIDO; X1 ES OXI, TIO, SULFINIL O SULFONIL; AR2 ES FENILENO OPCIONALMENTE SUSTITUIDO, O UNA MOLECULA DE 6 MIEMBROS DE HETEROCICLENO CONTENIENDO HASTA 3 ATOMOS DE N; R1 Y R2 JUNTOS FORMAN UN GRUPO DE LA FORMULA -A2-X2-A3 O, SULFINIL, DULFONIL O IMINO; Y R3 ES (1-6C)ALQUIL, (2-6C)ALQUENIL, (2-6C)ALQUINIL Y (1-4C)ALQUIL SUSTITUIDO.
ES90306763T 1989-07-18 1990-06-20 Eteres ciclicos de diarileter. Expired - Lifetime ES2056383T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89402047 1989-07-18

Publications (1)

Publication Number Publication Date
ES2056383T3 true ES2056383T3 (es) 1994-10-01

Family

ID=8202978

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90306763T Expired - Lifetime ES2056383T3 (es) 1989-07-18 1990-06-20 Eteres ciclicos de diarileter.

Country Status (16)

Country Link
US (1) US5137913A (es)
EP (1) EP0409412B1 (es)
JP (1) JPH0356476A (es)
AT (1) ATE108785T1 (es)
AU (1) AU630709B2 (es)
CA (1) CA2019543A1 (es)
DE (1) DE69010795T2 (es)
DK (1) DK0409412T3 (es)
ES (1) ES2056383T3 (es)
FI (1) FI903623A7 (es)
IE (1) IE902113A1 (es)
IL (1) IL94733A0 (es)
NO (1) NO903186L (es)
NZ (1) NZ234057A (es)
PT (1) PT94721A (es)
ZA (1) ZA905246B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
GB9300894D0 (en) * 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
EP0555067A1 (en) * 1992-02-07 1993-08-11 Zeneca Limited Hydroxylamine derivatives as 5-lipoxygenase inhibitors
CA2094465A1 (en) * 1992-04-23 1993-10-24 Pierre Andre Raymond Bruneau Cycloalkane derivatives
CA2095006A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Oxime derivatives
CA2095005A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Hydroxylamine derivatives
AU4444393A (en) * 1992-09-01 1994-03-10 Zeneca Limited Pyrrolidine derivatives
WO1994005638A1 (en) * 1992-09-02 1994-03-17 Abbott Laboratories Trans 1,4-diether cyclohexane inhibitors of 5-lipoxygenase
US5407959A (en) * 1993-11-12 1995-04-18 Abbott Laboratories (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
US5446062A (en) * 1993-11-12 1995-08-29 Abbott Laboratories ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase
US5891460A (en) * 1995-06-07 1999-04-06 University Of Southern California University Park Campus Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661917A (en) * 1970-05-21 1972-05-09 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols
US4100296A (en) * 1975-12-12 1978-07-11 Ciba-Geigy Corporation Dioxolane derivatives
FR2348205A1 (fr) * 1976-04-15 1977-11-10 France Etat Procede de preparation de la dibenzo (b,f) oxazepine -1,4
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4625034A (en) * 1985-02-04 1986-11-25 Usv Pharmaceutical Corp. 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
EP0271287A3 (en) * 1986-12-11 1990-06-13 Merck Frosst Canada Inc. Quinoline dioic acids and amides
EP0276196B1 (de) * 1987-01-19 1991-09-18 Ciba-Geigy Ag Substituierte Dioxolanderivate
US4920132A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920130A (en) * 1987-11-02 1990-04-24 Rorer Pharamceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920133A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920131A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4918081A (en) * 1988-06-20 1990-04-17 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene d4
EP0349062A1 (en) * 1988-06-27 1990-01-03 Merck Frosst Canada Inc. Quinoline ether alkanoic acid
GB8927287D0 (en) * 1988-12-23 1990-01-31 Ici Plc Cyclic ether derivatives

Also Published As

Publication number Publication date
AU5758090A (en) 1991-01-24
NZ234057A (en) 1993-02-25
EP0409412B1 (en) 1994-07-20
NO903186L (no) 1991-01-21
CA2019543A1 (en) 1991-01-18
DK0409412T3 (da) 1994-10-24
NO903186D0 (no) 1990-07-17
EP0409412A2 (en) 1991-01-23
DE69010795T2 (de) 1994-10-27
PT94721A (pt) 1991-03-20
DE69010795D1 (de) 1994-08-25
ATE108785T1 (de) 1994-08-15
IL94733A0 (en) 1991-04-15
EP0409412A3 (en) 1991-07-24
US5137913A (en) 1992-08-11
FI903623A7 (fi) 1991-01-19
IE902113A1 (en) 1991-06-19
ZA905246B (en) 1991-03-27
JPH0356476A (ja) 1991-03-12
FI903623A0 (fi) 1990-07-18
AU630709B2 (en) 1992-11-05

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