ES2058923T3 - Sistema para terapia neurologica. - Google Patents

Sistema para terapia neurologica.

Info

Publication number
ES2058923T3
ES2058923T3 ES90910077T ES90910077T ES2058923T3 ES 2058923 T3 ES2058923 T3 ES 2058923T3 ES 90910077 T ES90910077 T ES 90910077T ES 90910077 T ES90910077 T ES 90910077T ES 2058923 T3 ES2058923 T3 ES 2058923T3
Authority
ES
Spain
Prior art keywords
neurotransmitter
full
removable
therapy system
adjustment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90910077T
Other languages
English (en)
Inventor
Patrick Aebischer
Shelley R Winn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brown University Research Foundation Inc
Original Assignee
Brown University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brown University Research Foundation Inc filed Critical Brown University Research Foundation Inc
Application granted granted Critical
Publication of ES2058923T3 publication Critical patent/ES2058923T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0687—Skull, cranium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Electrotherapy Devices (AREA)
  • Massaging Devices (AREA)
  • Saccharide Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN UNOS DISPOSITIVOS DE TERAPIA NECROLOGICA PARA EL ENVIO, LOCALMENTE CONTROLADO, DE UN NEUROTRANSMISOR AL CEREBRO DE UN SUJETO QUE SUFRE DE UNA DEFICIENCIA O DISFUNCION NEUROTRANSMISORA. EN UNA DISPOSICION EL DISPOSITIVO (100) INCLUYE UN INSERTO POLIMERICO BIOCOMPATIBLE, INSERTABLE Y EXTRAIBLE (30) QUE INCLUYE UN NEUROTRANSMISOR. EN OTRA DISPOSICION DE ESTA INVENCION, EL DISPOSITIVO (200) INCLUYE UNA FUENTE NEUROTRANSMISORA EXTRAIBLE CON UNA CELULA (52) SECRETORA DEL NEUROTRANSMISOR ENCAPSULADA DENTRO DE UNA MEMBRANA SEMIPERMEABLE QUE LE PERMITE SU DIFUSION POR TODO EL NEUROTRANSMISOR INCLUYENDO ADEMAS UNA FUENTE DE FACTOR DE CRECIMIENTO ADYACENTE A LAS CELULAS SECRETORAS DEL NEUROTRANSMISOR.
ES90910077T 1989-06-21 1990-06-20 Sistema para terapia neurologica. Expired - Lifetime ES2058923T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36929689A 1989-06-21 1989-06-21

Publications (1)

Publication Number Publication Date
ES2058923T3 true ES2058923T3 (es) 1994-11-01

Family

ID=23454885

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90910077T Expired - Lifetime ES2058923T3 (es) 1989-06-21 1990-06-20 Sistema para terapia neurologica.

Country Status (12)

Country Link
EP (1) EP0478671B1 (es)
JP (1) JP2738881B2 (es)
KR (1) KR0141583B1 (es)
AT (1) ATE89485T1 (es)
AU (1) AU632827B2 (es)
CA (1) CA2062746C (es)
DE (1) DE69001672T2 (es)
DK (1) DK0478671T3 (es)
ES (1) ES2058923T3 (es)
FI (1) FI916066A0 (es)
NO (1) NO300488B1 (es)
WO (1) WO1990015637A2 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786216A (en) * 1987-11-17 1998-07-28 Cytotherapeutics, Inc. Inner-supported, biocompatible cell capsules
US5182111A (en) * 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
US5871472A (en) * 1987-11-17 1999-02-16 Brown University Research Foundation Planting devices for the focal release of neuroinhibitory compounds
US5773286A (en) * 1987-11-17 1998-06-30 Cytotherapeutics, Inc. Inner supported biocompatible cell capsules
US6517859B1 (en) 1990-05-16 2003-02-11 Southern Research Institute Microcapsules for administration of neuroactive agents
WO1991017772A1 (en) * 1990-05-16 1991-11-28 Southern Research Institute Controlled release dopamine and its use to stimulate nerve fiber growth
JPH06505186A (ja) * 1991-02-11 1994-06-16 オマーヤ，アユブ　ケー． 脊髄液駆動式人工器官
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
ATE156344T1 (de) * 1991-04-25 1997-08-15 Univ Brown Res Found Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte
SG47451A1 (en) * 1991-06-28 1998-04-17 Univ Brown Res Found Implantable therapy system
CA2111978A1 (en) * 1991-06-28 1993-01-07 Patrick Aebischer Renewable neural implant device and method
US5383873A (en) * 1992-12-09 1995-01-24 Regents Of The University Of Minnesota Smooth muscle chemical pacemaker
WO1994015663A1 (en) * 1992-12-30 1994-07-21 Brown University Research Foundation Implantable therapy systems and methods
WO1995004521A1 (en) 1993-08-10 1995-02-16 W.L. Gore & Associates, Inc. Cell encapsulating device
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US6110707A (en) * 1996-01-19 2000-08-29 Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
US6087129A (en) 1996-01-19 2000-07-11 Betagene, Inc. Recombinant expression of proteins from secretory cell lines
US6027721A (en) * 1996-05-20 2000-02-22 Cytotherapeutics, Inc. Device and method for encapsulated gene therapy
US6322962B1 (en) 1998-08-14 2001-11-27 Board Of Regents, The University Of Texas System Sterol-regulated Site-1 protease and assays of modulators thereof
US7745216B2 (en) 1999-02-10 2010-06-29 Curis, Inc. Methods and reagents for treating glucose metabolic disorders
US7396809B1 (en) 1999-02-10 2008-07-08 Curis, Inc. Methods and reagents for treating glucose metabolic disorders
EP2123293A3 (en) 2000-12-14 2010-09-08 Amylin Pharmaceuticals, Inc. Peptide YY and petide YY agonists for treatment of metabolic disorders
AUPR602401A0 (en) 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release delivery system
AUPR602501A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release pharmaceutical composition
AUPR610501A0 (en) * 2001-07-04 2001-07-26 Smart Drug Systems Inc Treatment of parasitic disease
SI2561860T1 (en) 2002-05-31 2018-05-31 Titan Pharmaceuticals, Inc. An implantable polymeric device for prolonged release of buprenorphine
PT1610791E (pt) 2003-03-31 2011-05-23 Titan Pharmaceuticals Inc Dispositivo polim?rico implant?vel para liberta??o sustentada de agonista da dopamina
CA2526101A1 (en) * 2003-05-30 2004-12-23 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of nalmefene
US8603969B2 (en) 2004-02-11 2013-12-10 Amylin Pharmaceuticals, Llc Pancreatic polypeptide family motifs and polypeptides comprising the same
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
JP2010252924A (ja) * 2009-04-22 2010-11-11 Olympus Corp カテーテルおよび薬剤投与装置
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device
GB8403138D0 (en) * 1984-02-07 1984-03-14 Graham N B Sustained release of active ingredient
US4883666A (en) * 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells

Also Published As

Publication number Publication date
JP2738881B2 (ja) 1998-04-08
CA2062746A1 (en) 1990-12-22
WO1990015637A2 (en) 1990-12-27
ATE89485T1 (de) 1993-06-15
EP0478671B1 (en) 1993-05-19
DE69001672T2 (de) 1993-12-23
AU632827B2 (en) 1993-01-14
DE69001672D1 (de) 1993-06-24
CA2062746C (en) 1999-02-02
NO915074L (no) 1992-01-31
WO1990015637A3 (en) 1991-04-04
NO300488B1 (no) 1997-06-09
EP0478671A1 (en) 1992-04-08
KR0141583B1 (ko) 1998-06-15
NO915074D0 (no) 1991-12-20
FI916066A7 (fi) 1991-12-20
DK0478671T3 (da) 1993-10-18
AU5856590A (en) 1991-01-08
FI916066A0 (fi) 1991-12-20
JPH05500620A (ja) 1993-02-12

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