ES2058923T3 - Sistema para terapia neurologica. - Google Patents

Sistema para terapia neurologica.

Info

Publication number
ES2058923T3
ES2058923T3 ES90910077T ES90910077T ES2058923T3 ES 2058923 T3 ES2058923 T3 ES 2058923T3 ES 90910077 T ES90910077 T ES 90910077T ES 90910077 T ES90910077 T ES 90910077T ES 2058923 T3 ES2058923 T3 ES 2058923T3
Authority
ES
Spain
Prior art keywords
neurotransmitter
full
removable
therapy system
adjustment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90910077T
Other languages
English (en)
Inventor
Patrick Aebischer
Shelley R Winn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brown University Research Foundation Inc
Original Assignee
Brown University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brown University Research Foundation Inc filed Critical Brown University Research Foundation Inc
Application granted granted Critical
Publication of ES2058923T3 publication Critical patent/ES2058923T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0687—Skull, cranium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Massaging Devices (AREA)
  • Eye Examination Apparatus (AREA)
  • Electrotherapy Devices (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE DESCRIBEN UNOS DISPOSITIVOS DE TERAPIA NECROLOGICA PARA EL ENVIO, LOCALMENTE CONTROLADO, DE UN NEUROTRANSMISOR AL CEREBRO DE UN SUJETO QUE SUFRE DE UNA DEFICIENCIA O DISFUNCION NEUROTRANSMISORA. EN UNA DISPOSICION EL DISPOSITIVO (100) INCLUYE UN INSERTO POLIMERICO BIOCOMPATIBLE, INSERTABLE Y EXTRAIBLE (30) QUE INCLUYE UN NEUROTRANSMISOR. EN OTRA DISPOSICION DE ESTA INVENCION, EL DISPOSITIVO (200) INCLUYE UNA FUENTE NEUROTRANSMISORA EXTRAIBLE CON UNA CELULA (52) SECRETORA DEL NEUROTRANSMISOR ENCAPSULADA DENTRO DE UNA MEMBRANA SEMIPERMEABLE QUE LE PERMITE SU DIFUSION POR TODO EL NEUROTRANSMISOR INCLUYENDO ADEMAS UNA FUENTE DE FACTOR DE CRECIMIENTO ADYACENTE A LAS CELULAS SECRETORAS DEL NEUROTRANSMISOR.
ES90910077T 1989-06-21 1990-06-20 Sistema para terapia neurologica. Expired - Lifetime ES2058923T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36929689A 1989-06-21 1989-06-21

Publications (1)

Publication Number Publication Date
ES2058923T3 true ES2058923T3 (es) 1994-11-01

Family

ID=23454885

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90910077T Expired - Lifetime ES2058923T3 (es) 1989-06-21 1990-06-20 Sistema para terapia neurologica.

Country Status (12)

Country Link
EP (1) EP0478671B1 (es)
JP (1) JP2738881B2 (es)
KR (1) KR0141583B1 (es)
AT (1) ATE89485T1 (es)
AU (1) AU632827B2 (es)
CA (1) CA2062746C (es)
DE (1) DE69001672T2 (es)
DK (1) DK0478671T3 (es)
ES (1) ES2058923T3 (es)
FI (1) FI916066A0 (es)
NO (1) NO300488B1 (es)
WO (1) WO1990015637A2 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182111A (en) * 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
WO1993000127A1 (en) * 1991-06-28 1993-01-07 Brown University Research Foundation Neural implant system
US5786216A (en) * 1987-11-17 1998-07-28 Cytotherapeutics, Inc. Inner-supported, biocompatible cell capsules
US5871472A (en) * 1987-11-17 1999-02-16 Brown University Research Foundation Planting devices for the focal release of neuroinhibitory compounds
US5773286A (en) * 1987-11-17 1998-06-30 Cytotherapeutics, Inc. Inner supported biocompatible cell capsules
US6517859B1 (en) 1990-05-16 2003-02-11 Southern Research Institute Microcapsules for administration of neuroactive agents
ES2185615T3 (es) * 1990-05-16 2003-05-01 Southern Res Inst Uso y liberacion controlada de las microcapsulas para estimular el crecimiento de la fibra nerviosa.
EP0571525A1 (en) * 1991-02-11 1993-12-01 OMMAYA, Ayub K. Spinal fluid driven artificial organ
SG47470A1 (en) * 1991-04-25 1998-04-17 Univ Brown Res Found Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
EP0766576A1 (en) * 1991-06-28 1997-04-09 Brown University Research Foundation Renewable neural implant device
US5383873A (en) * 1992-12-09 1995-01-24 Regents Of The University Of Minnesota Smooth muscle chemical pacemaker
AU6226894A (en) * 1992-12-30 1994-08-15 Brown University Research Foundation Implantable therapy systems and methods
DE69433970T2 (de) 1993-08-10 2005-08-11 W.L. Gore & Associates, Inc., Newark Zelleinkapselungsvorrichtung
AU6854696A (en) * 1995-09-22 1997-04-09 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US6087129A (en) 1996-01-19 2000-07-11 Betagene, Inc. Recombinant expression of proteins from secretory cell lines
US6110707A (en) * 1996-01-19 2000-08-29 Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
US6027721A (en) * 1996-05-20 2000-02-22 Cytotherapeutics, Inc. Device and method for encapsulated gene therapy
US6322962B1 (en) 1998-08-14 2001-11-27 Board Of Regents, The University Of Texas System Sterol-regulated Site-1 protease and assays of modulators thereof
IL144703A (en) 1999-02-10 2010-04-15 Curis Inc Use of peptide yy for the preparation of a pharmaceutical composition for enhancing pancreatic cell differentiation
US7745216B2 (en) 1999-02-10 2010-06-29 Curis, Inc. Methods and reagents for treating glucose metabolic disorders
EP2123293A3 (en) 2000-12-14 2010-09-08 Amylin Pharmaceuticals, Inc. Peptide YY and petide YY agonists for treatment of metabolic disorders
AUPR602401A0 (en) 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release delivery system
AUPR602501A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release pharmaceutical composition
AUPR610501A0 (en) * 2001-07-04 2001-07-26 Smart Drug Systems Inc Treatment of parasitic disease
PT2561860T (pt) 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Dispositivo polimérico implantável para a libertação prolongada de buprenorfina
SI1610791T1 (sl) 2003-03-31 2011-05-31 Titan Pharmaceuticals Inc Implantibilna polimerna naprava za zadržano sproščanje dopaminskega agonista
US20050031668A1 (en) * 2003-05-30 2005-02-10 Patel Rajesh A. Implantable polymeric device for sustained release of nalmefene
EP1789440A4 (en) 2004-02-11 2008-03-12 Amylin Pharmaceuticals Inc REASONS FOR THE FAMILY OF PANCREATIC POLYPEPTIDES AND POLYPEPTIDES CONTAINING THEM
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
JP2010252924A (ja) * 2009-04-22 2010-11-11 Olympus Corp カテーテルおよび薬剤投与装置
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device
GB8403138D0 (en) * 1984-02-07 1984-03-14 Graham N B Sustained release of active ingredient
US4883666A (en) * 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells

Also Published As

Publication number Publication date
WO1990015637A2 (en) 1990-12-27
JPH05500620A (ja) 1993-02-12
CA2062746A1 (en) 1990-12-22
EP0478671B1 (en) 1993-05-19
AU5856590A (en) 1991-01-08
JP2738881B2 (ja) 1998-04-08
NO915074L (no) 1992-01-31
NO915074D0 (no) 1991-12-20
WO1990015637A3 (en) 1991-04-04
FI916066A7 (fi) 1991-12-20
AU632827B2 (en) 1993-01-14
DK0478671T3 (da) 1993-10-18
CA2062746C (en) 1999-02-02
DE69001672D1 (de) 1993-06-24
NO300488B1 (no) 1997-06-09
KR0141583B1 (ko) 1998-06-15
EP0478671A1 (en) 1992-04-08
DE69001672T2 (de) 1993-12-23
ATE89485T1 (de) 1993-06-15
FI916066A0 (fi) 1991-12-20

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