ES2060923T3 - Comprimido de accion doble. - Google Patents

Comprimido de accion doble.

Info

Publication number
ES2060923T3
ES2060923T3 ES90200313T ES90200313T ES2060923T3 ES 2060923 T3 ES2060923 T3 ES 2060923T3 ES 90200313 T ES90200313 T ES 90200313T ES 90200313 T ES90200313 T ES 90200313T ES 2060923 T3 ES2060923 T3 ES 2060923T3
Authority
ES
Spain
Prior art keywords
tablet
active ingredient
dose
dual
action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90200313T
Other languages
English (en)
Inventor
Richard John Dansereau
Michael John Kane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Pharmaceuticals Inc
Original Assignee
Norwich Eaton Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Eaton Pharmaceuticals Inc filed Critical Norwich Eaton Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2060923T3 publication Critical patent/ES2060923T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EL PRESENTE INVENTO PROPORCIONA UNA PASTILLA DE DOBLE ACCION CUYA COMPOSICION COMPRENDE: (A) UNA PASTILLA EXTERIOR CON UNA PRIMERA DOSIS DE INGREDIENTE ACTIVO DISPERSO EN UNA MATRIZ POLIMERICA HIDROFILICA CON PH INDEPENDIENTE; (B) UNA PASTILLA INTERIOR CON UNA SEGUNDA DOSIS DE INGREDIENTE ACTIVO EN UNA TASA DE EXCIPIENTE DE DISGREGACION RAPIDA. LA PASTILLA DE DOBLE ACCION ES ESPECIALMENTE EIFCAZ PARA AQUELLOS INGREDIENTES ACTIVOS CUYA MEDIA ES DE MENOS DE DOS HORAS Y CUYA ABSORCION DISMINUYE EN EL TRACTO GASTROINTESTINAL INFERIOR. ESNTRE LAS COMPOSICIONES DE PASTILLAS DE DOBLE ACCION LA PREFERIDA ES AQUELLA EN LA QUE EL INGREDIENTE ACTIVO TANTO EN LA PASTILLA INTERIOR COMO EN LA EXTERIOR ES LA GUAIFENESINA. DURANTE LA ADMINISTRACION, LA PASTILLA EXTERIOR PROPORCIONA UNA LIBERACION CONTROLADA DEL INGREDIENTE ACTIVO MIENTRAS QUE LA PASTILLA EXTERIOR PROPORCIONA UNA SEGUNDA DOSIS DE INGREDIENTE ACTIVO DESPUES DE QUE LA PASTILLA EXTERIOR SE HA DISUELTO PARCIALMENTE.
ES90200313T 1989-02-21 1990-02-12 Comprimido de accion doble. Expired - Lifetime ES2060923T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/314,672 US5032406A (en) 1989-02-21 1989-02-21 Dual-action tablet

Publications (1)

Publication Number Publication Date
ES2060923T3 true ES2060923T3 (es) 1994-12-01

Family

ID=23220946

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90200313T Expired - Lifetime ES2060923T3 (es) 1989-02-21 1990-02-12 Comprimido de accion doble.

Country Status (15)

Country Link
US (1) US5032406A (es)
EP (1) EP0384514B1 (es)
JP (1) JP2895146B2 (es)
KR (1) KR0173115B1 (es)
AT (1) ATE97571T1 (es)
AU (1) AU632793B2 (es)
CA (1) CA2010037C (es)
DE (1) DE69004708T2 (es)
DK (1) DK0384514T3 (es)
ES (1) ES2060923T3 (es)
IE (1) IE63311B1 (es)
IL (1) IL93424A (es)
NZ (1) NZ232604A (es)
PH (1) PH27331A (es)
ZA (1) ZA901261B (es)

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US5284659A (en) * 1990-03-30 1994-02-08 Cherukuri Subraman R Encapsulated flavor with bioadhesive character in pressed mints and confections
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DE69222006T2 (de) * 1991-10-30 1998-01-22 Glaxo Group Ltd Mehrschichtzusammensetzungen enthaltend Histamin- oder Serotonin- Antagonisten
DE69224809T2 (de) * 1991-12-30 1998-07-09 Akzo Nobel Nv Thyroaktive Zusammensetzung mit kontrollierter Freigabe
WO1993019741A1 (en) * 1992-03-31 1993-10-14 Benzon Pharma A/S A pharmaceutical formulation
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
IT1260505B (it) † 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
IT1264696B1 (it) * 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol
US5399359A (en) * 1994-03-04 1995-03-21 Edward Mendell Co., Inc. Controlled release oxybutynin formulations
US5399362A (en) * 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
US5595759A (en) * 1994-11-10 1997-01-21 Alza Corporation Process for providing therapeutic composition
EP0823255A4 (en) * 1995-04-03 1999-01-27 Chugai Pharmaceutical Co Ltd Pharmaceutical composition containing sucralfate
US5759574A (en) * 1995-05-15 1998-06-02 Bothe; Steven T. Tel-tale-tablets
IT1276689B1 (it) * 1995-06-09 1997-11-03 Applied Pharma Res Forma farmaceutica solida ad uso orale
US5807579A (en) * 1995-11-16 1998-09-15 F.H. Faulding & Co. Limited Pseudoephedrine combination pharmaceutical compositions
AU2068797A (en) * 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
KR19980077329A (ko) * 1997-04-18 1998-11-16 이범진 이중층 약물 함유 제어방출성 제제
US6143309A (en) * 1998-03-12 2000-11-07 Archimica (Florida), Inc. Delivery of hydroxy carboxylic acids
US6372254B1 (en) * 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
US6387381B2 (en) 1998-09-24 2002-05-14 Ez-Med Company Semi-moist oral delivery system
US6773716B2 (en) * 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
IT1313590B1 (it) * 1999-08-03 2002-09-09 Formenti Farmaceutici Spa Composizioni a rilascio controllato di acido acetilsalicilico.
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6955821B2 (en) * 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US8012504B2 (en) * 2000-04-28 2011-09-06 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US7838032B2 (en) * 2000-04-28 2010-11-23 Reckitt Benckiser Inc. Sustained release of guaifenesin
US7985420B2 (en) * 2000-04-28 2011-07-26 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
NZ527832A (en) * 2001-03-13 2006-03-31 Penwest Pharmaceuticals Co Chronotherapeutic dosage forms
JP2002326961A (ja) * 2001-04-27 2002-11-15 Taiyo Kagaku Co Ltd 打錠用滑沢剤
US20030012820A1 (en) * 2001-06-12 2003-01-16 Upadhyay Ajay Hasmukhlal Compressible guaifenesin compositions, method for making same and method for making compressed guaifenesin dosage forms therefrom
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
CA2461616A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
CA2481091A1 (en) * 2002-04-05 2003-10-23 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
EA007156B1 (ru) * 2002-04-15 2006-08-25 Адамс Лэборетриз, Инк. Замедленно высвобождающие лекарственные композиции гвайфенезина
DE10224108A1 (de) * 2002-05-29 2004-01-29 Grünenthal GmbH 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes Arzneimiitel mit verzögerter Wirkstofffreisetzung
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
EA200600598A1 (ru) * 2003-09-19 2006-08-25 Пенвест Фармасьютикалз Ко. Лекарственные формы замедленного высвобождения
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CN1327838C (zh) * 2004-07-08 2007-07-25 北京科信必成医药科技发展有限公司 维生素c口腔崩解片及其制备方法
CN1297263C (zh) * 2004-10-25 2007-01-31 北京科信必成医药科技发展有限公司 葡萄糖酸钙口腔崩解片及其制备工艺
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20060257473A1 (en) * 2005-05-11 2006-11-16 Porranee Puranajoti Extended release tablet
US8765178B2 (en) 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
US20090202633A1 (en) * 2008-01-03 2009-08-13 Siva Ramakrishna Velaga Extended release formulations of guaifenesin
WO2010028290A1 (en) * 2008-09-04 2010-03-11 Farnam Companies, Inc. Chewable sustained release formulations
TR201001903A2 (tr) 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Uzatılmış salımlı tiyokolşiklozit tablet.
GB201506755D0 (en) 2015-04-21 2015-06-03 Reckitt Benckiser Llc Novel pharmaceutical formulation
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
KR101684797B1 (ko) * 2015-08-27 2016-12-08 오철환 개폐구조를 갖는 글루건
WO2017062997A1 (en) 2015-10-09 2017-04-13 Reckitt Benckiser Llc Pharmaceutical formulation
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN112472679A (zh) * 2020-12-02 2021-03-12 上海汉维生物医药科技有限公司 双释放片及其制备方法

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Also Published As

Publication number Publication date
IE63311B1 (en) 1995-04-05
CA2010037C (en) 1995-10-31
NZ232604A (en) 1992-10-28
IL93424A (en) 1994-02-27
KR0173115B1 (ko) 1999-02-01
ZA901261B (en) 1990-11-28
DE69004708D1 (de) 1994-01-05
IE900629L (en) 1990-08-21
JPH03200724A (ja) 1991-09-02
DE69004708T2 (de) 1994-03-24
PH27331A (en) 1993-06-08
AU632793B2 (en) 1993-01-14
IL93424A0 (en) 1990-11-29
KR900012606A (ko) 1990-09-01
JP2895146B2 (ja) 1999-05-24
US5032406A (en) 1991-07-16
EP0384514A3 (en) 1991-04-03
CA2010037A1 (en) 1990-08-21
ATE97571T1 (de) 1993-12-15
AU4997090A (en) 1990-08-30
EP0384514B1 (en) 1993-11-24
DK0384514T3 (da) 1994-02-07
EP0384514A2 (en) 1990-08-29

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