ES2061043T3 - Compuestos macrolidos para el tratamiento de enfermedades reversibles obstructivas de las vias respiratorias. - Google Patents

Compuestos macrolidos para el tratamiento de enfermedades reversibles obstructivas de las vias respiratorias.

Info

Publication number
ES2061043T3
ES2061043T3 ES90908603T ES90908603T ES2061043T3 ES 2061043 T3 ES2061043 T3 ES 2061043T3 ES 90908603 T ES90908603 T ES 90908603T ES 90908603 T ES90908603 T ES 90908603T ES 2061043 T3 ES2061043 T3 ES 2061043T3
Authority
ES
Spain
Prior art keywords
treatment
compounds
reversible obstructive
respiratory tract
obstructive diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908603T
Other languages
English (en)
Inventor
Alan Anthony Norris
Dale Michael Jackson
Sohei Makino
Takeshi Fukuda
Ikuo Akutsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fisons Ltd
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898912935A external-priority patent/GB8912935D0/en
Priority claimed from JP2096045A external-priority patent/JPH03291225A/ja
Application filed by Fisons Ltd, Fujisawa Pharmaceutical Co Ltd filed Critical Fisons Ltd
Application granted granted Critical
Publication of ES2061043T3 publication Critical patent/ES2061043T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Non-Portable Lighting Devices Or Systems Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPUESTOS DE FORMULA (I) DONDE R1 Y R2 REPRESENTAN CONJUNTAMENTE DOS ATOMOS VECINOS DE HIDROGENO, O UN SEGUNDO ENLACE ENTRE ATOMOS VECINOS DE CARBONO A LOS QUE ESTEN UNIDOS; R3 REPRESENTA H, OH, ALCOXI O UN HIDROXI PROTEGIDO; R4 REPRESENTA OH; R5 REPRESENTA H, ALQUILO O ALQUENILO; R6 Y R7 REPRESENTAN INDEPENDIENTEMENTE O, (H, OH), (H, HIDROXIDO PROTEGIDO) O (H, ALCOXI); X Y Y INDEPENDIENTEMENTE REPRESENTAN O, (H, OH) O (H, H); N ES 1 O 2; O UNOS DERIVADOS FARMACOLOGICAMENTE ACEPTABLES DE LOS ANTERIORES; PUEDEN SER UTILIZADOS PARA EL TRATAMIENTO DE ENFERMEDADES REVERSIBLES DE LAS VIAS RESPIRATORIAS, PARTICULARMENTE ASMA. TAMBIEN SE DESCRIBEN UNOS PREPARADOS QUE CONTIENEN DICHOS COMPUESTOS.
ES90908603T 1989-06-06 1990-06-06 Compuestos macrolidos para el tratamiento de enfermedades reversibles obstructivas de las vias respiratorias. Expired - Lifetime ES2061043T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898912935A GB8912935D0 (en) 1989-06-06 1989-06-06 Method of treatment
JP2096045A JPH03291225A (ja) 1990-04-09 1990-04-09 抗喘息薬

Publications (1)

Publication Number Publication Date
ES2061043T3 true ES2061043T3 (es) 1994-12-01

Family

ID=26295442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908603T Expired - Lifetime ES2061043T3 (es) 1989-06-06 1990-06-06 Compuestos macrolidos para el tratamiento de enfermedades reversibles obstructivas de las vias respiratorias.

Country Status (13)

Country Link
EP (1) EP0475994B1 (es)
JP (1) JP2508918B2 (es)
KR (1) KR0147852B1 (es)
AT (1) ATE111353T1 (es)
AU (1) AU639460B2 (es)
CA (1) CA2054203C (es)
DE (1) DE69012560T2 (es)
DK (1) DK0475994T3 (es)
ES (1) ES2061043T3 (es)
GR (1) GR1000738B (es)
IE (1) IE64214B1 (es)
PT (1) PT94292B (es)
WO (1) WO1990014826A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208228A (en) * 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
US5143918A (en) * 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5147877A (en) * 1991-04-18 1992-09-15 Merck & Co. Inc. Semi-synthetic immunosuppressive macrolides
US5514686A (en) * 1991-04-26 1996-05-07 Fujisawa Pharmaceutical Co., Ltd. Use of macrolide compounds for eye diseases
US5565560A (en) * 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5250678A (en) 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5162334A (en) * 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
US5208241A (en) * 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
ZA926812B (en) 1991-09-09 1993-04-28 Merck & Co Inc O-heteroaryl,o-alkylheteroaryl,o-alkenylheteroaryl and o-alkynylheteroaryl macrolides having immunosupressive activity
GB9218027D0 (en) * 1992-08-25 1992-10-14 Fisons Plc Novel method of treatment
US5693648A (en) * 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
AU2002952559A0 (en) * 2002-11-08 2002-11-21 Fujisawa Pharmaceutical Co., Ltd. New use
WO2004069223A2 (en) * 2003-02-06 2004-08-19 Cipla Ltd Pharmaceutical compositions comprising immunosuppressants and uses thereof
CA2552305A1 (en) * 2003-12-30 2005-07-14 Astellas Pharma Inc. Use of macrolides for treating or preventing airflow obstruction
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
KR102293890B1 (ko) * 2018-12-11 2021-08-27 주식회사 몰젠바이오 신규 화합물 및 이를 포함하는 발모 촉진용 조성물
US12011497B2 (en) 2018-12-11 2024-06-18 Molgenbio Co. Ltd. Compounds, compositions containing same, and use thereof for promoting hair growth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
GB8802229D0 (en) * 1988-02-02 1988-03-02 Fujisawa Pharmaceutical Co Ws-9326 & its derivatives

Also Published As

Publication number Publication date
CA2054203A1 (en) 1990-12-07
EP0475994B1 (en) 1994-09-14
KR0147852B1 (ko) 1998-08-17
DE69012560D1 (de) 1994-10-20
ATE111353T1 (de) 1994-09-15
AU639460B2 (en) 1993-07-29
DE69012560T2 (de) 1995-03-09
JPH05503283A (ja) 1993-06-03
AU5721490A (en) 1991-01-07
IE64214B1 (en) 1995-07-26
WO1990014826A1 (en) 1990-12-13
GR1000738B (el) 1992-12-30
JP2508918B2 (ja) 1996-06-19
DK0475994T3 (da) 1995-01-09
PT94292B (pt) 1997-01-31
PT94292A (pt) 1991-02-08
EP0475994A1 (en) 1992-03-25
IE902002L (en) 1990-12-06
GR900100428A (en) 1991-11-15
KR920700638A (ko) 1992-08-10
CA2054203C (en) 2001-08-21

Similar Documents

Publication Publication Date Title
ES2061043T3 (es) Compuestos macrolidos para el tratamiento de enfermedades reversibles obstructivas de las vias respiratorias.
ES528123A0 (es) Procedimiento de preparacion de derivados de xantina (como divisional de la solicitud de patente de invencion no.515936, solicitada el 24.9.82)
TW243449B (es)
PL304063A1 (en) Derivatives of 5-amino 9-methyl-7-pyrolidine-quinoline-3-carboxylic acid, method of obtaining them, pharmaceutic agent containing such compounds and medical treatment method employing them
SE8700714L (sv) Anvendning av substituerade 4-fenyl-4-oxo-2-butensyraderivat for framstellning av lekemedel for behandling av sjukdomar i matsmeltningskanalen och som antiulcerost lekemedel
DK196688D0 (da) Bicykliske forbindelser og fremgangsmaade til fremstilling deraf
NZ332687A (en) use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
ES2118650T3 (es) Derivados de la quinolina-4-carbonilguanidina, procedimiento para la preparacion de los mismos y preparaciones farmaceuticas que contienen los compuestos.
ATE198746T1 (de) Pyrimidinderivate und pharmazeutische zusammensetzungen
HUT62890A (en) Process for producing benzothiazole derivatives and pharmaceutical compositions comprising such compounds
US4472424A (en) Esters of 2-thenoylmercaptopropionylglycine with substituted hydroxybenzenes, process for their preparation and pharmaceutical compositions containing same
EP1291349A4 (en) MALTO-OLIGOSACCHARIDE DERIVATIVES AND USE THEREOF
ATE109485T1 (de) Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
TW353071B (en) Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
JPS57139083A (en) Cephalosporin derivative
IT1248525B (it) Derivati dell'eseridina utili per il trattamento delle malattie associate a disordini colinergici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 475994

Country of ref document: ES