ES2061673T3 - Inactivacion de virus y bacterias. - Google Patents
Inactivacion de virus y bacterias.Info
- Publication number
- ES2061673T3 ES2061673T3 ES88308908T ES88308908T ES2061673T3 ES 2061673 T3 ES2061673 T3 ES 2061673T3 ES 88308908 T ES88308908 T ES 88308908T ES 88308908 T ES88308908 T ES 88308908T ES 2061673 T3 ES2061673 T3 ES 2061673T3
- Authority
- ES
- Spain
- Prior art keywords
- inactivation
- viruses
- bacteria
- compositions
- inactivating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000894006 Bacteria Species 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000002779 inactivation Effects 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910001385 heavy metal Inorganic materials 0.000 abstract 1
- 229940031551 inactivated vaccine Drugs 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
- A61K39/225—Porcine transmissible gastroenteritis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/265—Infectious rhinotracheitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20061—Methods of inactivation or attenuation
- C12N2770/20063—Methods of inactivation or attenuation by chemical treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Steroid Compounds (AREA)
- Catalysts (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS ESTERILES PARA USAR EN VACUNAS FARMACEUTICAS ESPECIALMENTE TERAPEUTICAMENTE PARA SU EMPLEO EN PROFILAXIS, SE PREPARAN POR INACTIVACION DEL VIRUS VIVO O BACTERIA CON UN ACIDO AECORBICO Y/O UNA SAL DE ESTE EN PRESENCIA DE OXIGENO Y UNA FUENTE DE IONES METALICOS PESADOS. TAMBIEN SE HAN DESCUBIERTO METODOS PARA EL TRATAMIENTO DE ANIMALES INCLUIDO EL HOMBRE CON CADA COMPOSICION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10182287A | 1987-09-28 | 1987-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2061673T3 true ES2061673T3 (es) | 1994-12-16 |
Family
ID=22286587
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88308908T Expired - Lifetime ES2061673T3 (es) | 1987-09-28 | 1988-09-26 | Inactivacion de virus y bacterias. |
| ES88308907T Expired - Lifetime ES2067474T3 (es) | 1987-09-28 | 1988-09-26 | Virus tgev del cerdo como vacuna para perros. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88308907T Expired - Lifetime ES2067474T3 (es) | 1987-09-28 | 1988-09-26 | Virus tgev del cerdo como vacuna para perros. |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP0310316B1 (es) |
| JP (2) | JP2715114B2 (es) |
| KR (2) | KR0135426B1 (es) |
| AT (2) | ATE117899T1 (es) |
| AU (2) | AU624339B2 (es) |
| CA (2) | CA1331562C (es) |
| DE (2) | DE3852918T2 (es) |
| DK (2) | DK175379B1 (es) |
| ES (2) | ES2061673T3 (es) |
| GR (1) | GR3015608T3 (es) |
| IE (2) | IE60950B1 (es) |
| NZ (2) | NZ226333A (es) |
| PT (2) | PT88591B (es) |
| ZA (2) | ZA887196B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60950B1 (en) * | 1987-09-28 | 1994-09-07 | Beecham Inc | Inactivation of viruses and bacteria |
| DE69020573T3 (de) * | 1989-09-25 | 1999-12-16 | Crc Technology Ltd., London | Verfahren zur wachstumshemmung von stammzellen. |
| US5276142A (en) * | 1989-12-11 | 1994-01-04 | American Cyanamid Company | Process for purification of a 69000 dalton antigenic protein from Bordetella pertussis |
| ES2186694T3 (es) * | 1990-06-07 | 2003-05-16 | Bayer Ag | Vacuna bacteriana para el tratamiento de necrosis hepatica causada por f. necrophorum. |
| US6372224B1 (en) | 1990-11-14 | 2002-04-16 | Pfizer Inc. | Canine coronavirus S gene and uses therefor |
| US6057436A (en) * | 1990-11-14 | 2000-05-02 | Pfizer Inc. | Canine coronavirus S gene and uses therefor |
| JPH0813753B2 (ja) * | 1992-05-22 | 1996-02-14 | 株式会社微生物化学研究所 | 牛伝染性鼻気管炎ウイルス感染症、牛ウイルス性下痢−粘膜病ウイルス感染症、パラインフルエンザ３型ウイルス感染症、牛ｒｓウイルス感染症および牛アデノ７型ウイルス感染症５種混合生ワクチン |
| WO1994007534A1 (en) * | 1992-10-05 | 1994-04-14 | Sanofi Animal Health, Inc. | High potency vaccines |
| JP2521226B2 (ja) * | 1993-01-28 | 1996-08-07 | 株式会社微生物化学研究所 | 犬用多種混合ワクチン |
| EP0612532A3 (en) * | 1993-02-26 | 1998-02-04 | Solvay Animal Health, Inc. | Canine coronavirus vaccine from feline enteric coronavirus |
| US5750112A (en) * | 1993-02-26 | 1998-05-12 | Solvay Animal Health, Inc. | Canine coronavirus vaccine from feline enteric coronavirus |
| US5362442A (en) | 1993-07-22 | 1994-11-08 | 2920913 Canada Inc. | Method for sterilizing products with gamma radiation |
| BR9407182A (pt) * | 1993-08-06 | 1996-09-17 | Connaught Lab | Composição imunogênica processo de preparo de composição não-imunopotencializadora imunogênica processo para determinar a presença de anticorpos estojo para diagnóstico para determinar a presença de anticorpos e virus sincicial respiratório humano inativado purificado |
| CA2184132C (en) | 1995-09-21 | 2011-03-15 | Kristina J. Hennessy | An adjuvanted vaccine which is substantially free of non-host albumin |
| US6682746B2 (en) | 1995-09-21 | 2004-01-27 | Kristina J. Hennessy | Adjuvanted vaccine which is substantially free of non-host albumin |
| US5853715A (en) * | 1996-08-16 | 1998-12-29 | Bayer Corporation | Cross-protective equine herpesvirus preparations and method of making and using the same |
| UA78180C2 (uk) * | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| EP0978286A1 (en) * | 1998-08-07 | 2000-02-09 | Bayer Corporation | Cross-protective equine herpesvirus preparations and method of making and using the same |
| US6682695B2 (en) | 2001-03-23 | 2004-01-27 | Clearant, Inc. | Methods for sterilizing biological materials by multiple rates |
| US6696060B2 (en) | 2001-06-14 | 2004-02-24 | Clearant, Inc. | Methods for sterilizing preparations of monoclonal immunoglobulins |
| US6946098B2 (en) | 2001-08-10 | 2005-09-20 | Clearant, Inc. | Methods for sterilizing biological materials |
| US7252799B2 (en) | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
| US6749851B2 (en) | 2001-08-31 | 2004-06-15 | Clearant, Inc. | Methods for sterilizing preparations of digestive enzymes |
| US6783968B2 (en) | 2001-09-24 | 2004-08-31 | Clearant, Inc. | Methods for sterilizing preparations of glycosidases |
| US20030095890A1 (en) | 2001-09-24 | 2003-05-22 | Shirley Miekka | Methods for sterilizing biological materials containing non-aqueous solvents |
| US6908591B2 (en) | 2002-07-18 | 2005-06-21 | Clearant, Inc. | Methods for sterilizing biological materials by irradiation over a temperature gradient |
| US7682619B2 (en) | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
| CN103709248B (zh) * | 2013-12-24 | 2019-07-16 | 北京大北农科技集团股份有限公司动物医学研究中心 | 一种抗猪传染性胃肠炎病毒高免血清及其制备方法 |
| DE202020001666U1 (de) | 2020-04-21 | 2020-06-08 | Walther Enßlin | Imprägnierung der Oberfläche von Kleidung, Schutzkleidung, Gewebehandschuhen gegen Viren aus den Tröpfchen der Atemluft |
| DE202020003865U1 (de) | 2020-09-11 | 2021-09-22 | Karin Emde | Einfangen und Vernichten von Viren und andere Mikroorganismen in Raumluft und Raumluftfiltern |
| DE102021001635A1 (de) | 2021-03-27 | 2022-09-29 | Karin Emde | Abfangen und Vernichten von Viren und andere Mikroorganismen auf Oberflächen, in Raumluft, in der Abluft von Staubsaugern und in Raumluftfiltern. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3145144A (en) * | 1951-08-09 | 1964-08-18 | Takeda Pharmacentical Ind Ltd | Process for manufacturing chromium treated vaccines |
| FR1488212A (fr) * | 1964-06-22 | 1967-07-13 | Behringwerke Ag | Procédé permettant d'atténuer le virus de la fièvre aphteuse |
| CH466894A (de) * | 1964-09-22 | 1968-12-31 | Diamond Lab Inc | Verfahren zur Herstellung eines Vakzins gegen infektiöse Gastroenteritis |
| US3925544A (en) * | 1971-07-12 | 1975-12-09 | Univ Southern Illinois | Bovine vaccines and methods of making and using same |
| US3907986A (en) * | 1972-12-18 | 1975-09-23 | Rit Rech Ind Therapeut | Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof |
| JPS5531762B2 (es) * | 1973-03-28 | 1980-08-20 | ||
| EP0000677B1 (en) * | 1977-07-22 | 1981-08-05 | Merck & Co. Inc. | Parainfluenza virus vaccine and its preparation |
| JPS55104215A (en) * | 1979-02-06 | 1980-08-09 | Merck & Co Inc | Parainfluenza virus vaccine and its manufacture |
| GB8502399D0 (en) * | 1985-01-31 | 1985-03-06 | Akzo Nv | Canine parvovirus vaccines |
| IE60950B1 (en) * | 1987-09-28 | 1994-09-07 | Beecham Inc | Inactivation of viruses and bacteria |
-
1988
- 1988-09-26 IE IE290988A patent/IE60950B1/en not_active IP Right Cessation
- 1988-09-26 CA CA000578384A patent/CA1331562C/en not_active Expired - Fee Related
- 1988-09-26 AT AT88308907T patent/ATE117899T1/de not_active IP Right Cessation
- 1988-09-26 PT PT88591A patent/PT88591B/pt not_active IP Right Cessation
- 1988-09-26 DE DE3852918T patent/DE3852918T2/de not_active Expired - Fee Related
- 1988-09-26 EP EP88308907A patent/EP0310316B1/en not_active Expired - Lifetime
- 1988-09-26 DK DK198805341A patent/DK175379B1/da not_active IP Right Cessation
- 1988-09-26 ES ES88308908T patent/ES2061673T3/es not_active Expired - Lifetime
- 1988-09-26 CA CA000578383A patent/CA1332919C/en not_active Expired - Fee Related
- 1988-09-26 ES ES88308907T patent/ES2067474T3/es not_active Expired - Lifetime
- 1988-09-26 AU AU22814/88A patent/AU624339B2/en not_active Ceased
- 1988-09-26 AU AU22843/88A patent/AU624081B2/en not_active Ceased
- 1988-09-26 NZ NZ226333A patent/NZ226333A/xx unknown
- 1988-09-26 DE DE88308908T patent/DE3886332T2/de not_active Expired - Fee Related
- 1988-09-26 ZA ZA887196A patent/ZA887196B/xx unknown
- 1988-09-26 ZA ZA887195A patent/ZA887195B/xx unknown
- 1988-09-26 NZ NZ226332A patent/NZ226332A/xx unknown
- 1988-09-26 EP EP88308908A patent/EP0310317B1/en not_active Expired - Lifetime
- 1988-09-26 AT AT88308908T patent/ATE98680T1/de not_active IP Right Cessation
- 1988-09-26 PT PT88590A patent/PT88590B/pt active IP Right Grant
- 1988-09-26 DK DK198805342A patent/DK175308B1/da not_active IP Right Cessation
- 1988-09-26 IE IE290888A patent/IE66015B1/en not_active IP Right Cessation
- 1988-09-28 JP JP63243734A patent/JP2715114B2/ja not_active Expired - Lifetime
- 1988-09-28 JP JP63243735A patent/JP2733844B2/ja not_active Expired - Fee Related
- 1988-09-28 KR KR1019880012562A patent/KR0135426B1/ko not_active Expired - Fee Related
- 1988-09-28 KR KR1019880012563A patent/KR890004725A/ko not_active Ceased
-
1995
- 1995-03-23 GR GR950400684T patent/GR3015608T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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