ES2062312T3 - Uso de gestodeno para la produccion de agentes farmaceuticos. - Google Patents
Uso de gestodeno para la produccion de agentes farmaceuticos.Info
- Publication number
- ES2062312T3 ES2062312T3 ES90250128T ES90250128T ES2062312T3 ES 2062312 T3 ES2062312 T3 ES 2062312T3 ES 90250128 T ES90250128 T ES 90250128T ES 90250128 T ES90250128 T ES 90250128T ES 2062312 T3 ES2062312 T3 ES 2062312T3
- Authority
- ES
- Spain
- Prior art keywords
- gestodeno
- production
- pharmaceutical agents
- beta
- estradien
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SIGSPDASOTUPFS-XUDSTZEESA-N gestodene Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](C=C4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 SIGSPDASOTUPFS-XUDSTZEESA-N 0.000 title abstract 3
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- 102000009618 Transforming Growth Factors Human genes 0.000 abstract 1
- 108010009583 Transforming Growth Factors Proteins 0.000 abstract 1
- 229940046836 anti-estrogen Drugs 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 201000008275 breast carcinoma Diseases 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- 229960005352 gestodene Drugs 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
ESTEROIDES QUE TIENEN UN ENLACE DOBLE (15, 16), ESPECIALMENTE LA GESTODENA (17(ALFA)-ETINIL-17(BETA)-HIDROXI-18-METIL-4,15-ESTRADIEN-3-0NA), PUEDE SER USADO PARA EL TRATAMIENTO DE CARCINOMAS QUE PUEDEN INHIBIRSE EN SU CRECIMIENTO MEDIANTE LA PROTEINA TGF(BETA) (FACTOR DE CRECIMIENTO TUMORAL (BETA)), ESPECIALMENTE EL CARCINOMA DE PULMON. AL MENOS UN ANTIESTROGENO PUEDE A SI MISMO SER ADMINISTRADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3916381A DE3916381A1 (de) | 1989-05-17 | 1989-05-17 | Verwendung von gestoden zur herstellung von arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2062312T3 true ES2062312T3 (es) | 1994-12-16 |
Family
ID=6381002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90250128T Expired - Lifetime ES2062312T3 (es) | 1989-05-17 | 1990-05-17 | Uso de gestodeno para la produccion de agentes farmaceuticos. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0399631B1 (es) |
| JP (1) | JPH0386826A (es) |
| CN (1) | CN1047298A (es) |
| AT (1) | ATE101519T1 (es) |
| AU (1) | AU640139B2 (es) |
| CA (1) | CA2016895A1 (es) |
| DD (1) | DD298883A5 (es) |
| DE (2) | DE3916381A1 (es) |
| DK (1) | DK0399631T3 (es) |
| ES (1) | ES2062312T3 (es) |
| HU (1) | HUT54501A (es) |
| IE (1) | IE65717B1 (es) |
| IL (1) | IL94417A (es) |
| PT (1) | PT94051B (es) |
| ZA (1) | ZA903803B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19739916C2 (de) * | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
| FR2833837B1 (fr) * | 2001-12-21 | 2005-08-05 | Oreal | Composition pour la teinture d'oxydation des fibres keratiniques comprenant un amide d'acide gras de colza oxyethylene |
| JP4775563B2 (ja) * | 2006-03-31 | 2011-09-21 | Ｎｏｋ株式会社 | センターベアリングサポート |
| JP2009078123A (ja) | 2007-09-07 | 2009-04-16 | Morito Co Ltd | 取付部品と取付対象物との連結方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0310542B1 (de) * | 1987-10-01 | 1994-06-08 | Schering Aktiengesellschaft | Antigestagen- und antiöstrogenwirksame Verbindungen zur Behandlung hormonabhängiger Tumoren |
-
1989
- 1989-05-17 DE DE3916381A patent/DE3916381A1/de not_active Withdrawn
-
1990
- 1990-05-16 IL IL9441790A patent/IL94417A/en not_active IP Right Cessation
- 1990-05-16 PT PT94051A patent/PT94051B/pt not_active IP Right Cessation
- 1990-05-16 CA CA002016895A patent/CA2016895A1/en not_active Abandoned
- 1990-05-16 HU HU903055A patent/HUT54501A/hu unknown
- 1990-05-17 CN CN90103702A patent/CN1047298A/zh active Pending
- 1990-05-17 AU AU55135/90A patent/AU640139B2/en not_active Ceased
- 1990-05-17 ZA ZA903803A patent/ZA903803B/xx unknown
- 1990-05-17 DE DE69006633T patent/DE69006633T2/de not_active Expired - Lifetime
- 1990-05-17 IE IE177590A patent/IE65717B1/en not_active IP Right Cessation
- 1990-05-17 AT AT90250128T patent/ATE101519T1/de not_active IP Right Cessation
- 1990-05-17 DD DD90340770A patent/DD298883A5/de not_active IP Right Cessation
- 1990-05-17 DK DK90250128.7T patent/DK0399631T3/da active
- 1990-05-17 EP EP90250128A patent/EP0399631B1/en not_active Expired - Lifetime
- 1990-05-17 JP JP2125615A patent/JPH0386826A/ja active Pending
- 1990-05-17 ES ES90250128T patent/ES2062312T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE101519T1 (de) | 1994-03-15 |
| DK0399631T3 (da) | 1994-06-06 |
| PT94051A (pt) | 1991-01-08 |
| CA2016895A1 (en) | 1990-11-17 |
| HU903055D0 (en) | 1990-09-28 |
| HUT54501A (en) | 1991-03-28 |
| IL94417A0 (en) | 1991-03-10 |
| AU640139B2 (en) | 1993-08-19 |
| DD298883A5 (de) | 1992-03-19 |
| DE69006633D1 (de) | 1994-03-31 |
| CN1047298A (zh) | 1990-11-28 |
| IL94417A (en) | 1995-07-31 |
| AU5513590A (en) | 1990-11-29 |
| DE69006633T2 (de) | 1994-08-25 |
| IE901775L (en) | 1990-11-17 |
| ZA903803B (en) | 1991-03-27 |
| EP0399631A1 (en) | 1990-11-28 |
| EP0399631B1 (en) | 1994-02-16 |
| IE65717B1 (en) | 1995-11-15 |
| JPH0386826A (ja) | 1991-04-11 |
| DE3916381A1 (de) | 1990-11-22 |
| PT94051B (pt) | 1996-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2042725T3 (es) | Procedimiento para preparar inhibidores de 5-alfa-estersa de esteroide. | |
| BG42837A3 (bg) | Метод за получаване на имуноглобулинови производни на винка алкалоиди | |
| DE69033703D1 (de) | Nichtglykosyliertes fgf-4 und dieses enthaltende präparate | |
| DE68915503D1 (de) | Zahnchirurgisches Gerät, geeignet für die Versorgung von gekoppelten Handstücken mit drei unterschiedlichen Fluida. | |
| GR82030B (es) | ||
| DK0416678T3 (da) | Topiske præparater indeholdende Defibrotid | |
| ES2062312T3 (es) | Uso de gestodeno para la produccion de agentes farmaceuticos. | |
| NZ222434A (en) | Tissue factor protein lacking its naturally associated phospholipid | |
| IT9020020A0 (it) | "n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono | |
| IT8420213A0 (it) | Procedimento per la preparazione di 1,8-diidrossi-10-acil-9-antroni, in particolare per l'uso nel trattamento di psoriasi. | |
| FI853854A7 (fi) | Joditriaminobentseeniyhdisteet, menetelmäniiden valmistamiseksi ja niiden käyttö röntgensäteiden varjoaineina. | |
| ZA872128B (en) | Chlorpheniramine therapy | |
| ZA849576B (en) | 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases | |
| DE69023459D1 (de) | Behandlung von pulmonarer Disfunktion mit 15-Keto-prostaglandin-Derivaten. | |
| ES8404693A1 (es) | Procedimiento de preparacion de nuevos amino-14 esteroides. | |
| ZA893310B (en) | Novel strobilurine derivatives,their preparation and their use | |
| DE3273979D1 (en) | 9,10-substituted 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-ones, process for their preparation and their use as medicaments | |
| EP0348664A3 (en) | Pharmaceutical compositions containing monoacetoacetins for treating tumours | |
| SE8802040D0 (sv) | New use | |
| ATE36957T1 (de) | N,n-diethyl-5-methyl-2h,1-benzothiopyrano-(4,3, - cd)-indazol-2-ethanamine, diese enthaltende zubereitungen und ihre verwendung. | |
| AU645042B2 (en) | Use of a polypeptide having the activity of gamma interferon for the preparation of pharmaceutical compositions intended for the treatment of primary cancers of the pleura | |
| IT8619249A0 (it) | Kit per la determinazione dell'attivita' proliferativa nei tumori umani. | |
| Seo | Recommendations for the Improvement of the Medical Licensing Examination | |
| MX9203715A (es) | Preparciones para el tratamiento del tejido aloinjertado. | |
| IT8420686A1 (it) | "procedimenti per la preparazione di derivati del bis-idrossietilmercapto-1,10 - decano"/ |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 399631 Country of ref document: ES |