ES2063783T3 - Factor de cristalino humano de estimulacion de colonias de granulocitos y procedimiento para su preparacion. - Google Patents

Factor de cristalino humano de estimulacion de colonias de granulocitos y procedimiento para su preparacion.

Info

Publication number
ES2063783T3
ES2063783T3 ES89110022T ES89110022T ES2063783T3 ES 2063783 T3 ES2063783 T3 ES 2063783T3 ES 89110022 T ES89110022 T ES 89110022T ES 89110022 T ES89110022 T ES 89110022T ES 2063783 T3 ES2063783 T3 ES 2063783T3
Authority
ES
Spain
Prior art keywords
preparation
stimulation
procedure
fec
human crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89110022T
Other languages
English (en)
Inventor
Sadao Tanaka
Toshio Akimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1-126392A external-priority patent/JP3004655B2/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2063783T3 publication Critical patent/ES2063783T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UN FACTOR ESTIMULANTE DE COLONIAS DE GRANULOCITOS CRISTALINO (FEC - G CRISTALINO) Y A UN PROCESO PARA SU PREPARACION. EL FEC - G CRISTALINO ES EXTREMADAMENTE PURO Y TIENE ALTA ACTIVIDAD Y BAJA ANTIGENICIDAD. ADEMAS LA CRISTALIZACION DEL FEC - G MEJORA SU ESTABILIDAD Y FACILITA SU MANEJO CUANDO SE ALMACENA Y FORMULA EN LOS TIPOS DE DOSIFICACION DESEADOS.
ES89110022T 1988-06-03 1989-06-02 Factor de cristalino humano de estimulacion de colonias de granulocitos y procedimiento para su preparacion. Expired - Lifetime ES2063783T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13711188 1988-06-03
JP23138888 1988-09-14
JP1-126392A JP3004655B2 (ja) 1988-06-03 1989-05-19 結晶性ヒト顆粒球コロニー刺激因子及びその製造方法

Publications (1)

Publication Number Publication Date
ES2063783T3 true ES2063783T3 (es) 1995-01-16

Family

ID=27315322

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89110022T Expired - Lifetime ES2063783T3 (es) 1988-06-03 1989-06-02 Factor de cristalino humano de estimulacion de colonias de granulocitos y procedimiento para su preparacion.

Country Status (4)

Country Link
EP (1) EP0344796B1 (es)
AT (1) ATE111921T1 (es)
DE (1) DE68918331T2 (es)
ES (1) ES2063783T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ236819A (en) * 1990-02-03 1993-07-27 Max Planck Gesellschaft Enzymatic cleavage of fusion proteins; fusion proteins; recombinant dna and pharmaceutical compositions
EP0955365A3 (en) * 1992-06-09 2000-12-20 Chiron Corporation Crystallization of M-CSF
US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
KR100241257B1 (ko) * 1997-05-22 2000-02-01 한승수 인체 과립구 콜로니 자극 인자 활성물질 및 그것의 제조방법
JP2000319298A (ja) * 1999-03-04 2000-11-21 Seibutsu Bunshi Kogaku Kenkyusho:Kk 蛋白質複合体の結晶、構造座標、及び構造座標の使用
US6831158B2 (en) 2000-01-10 2004-12-14 Maxygen Holdings Ltd. G-CSF conjugates
US6555660B2 (en) 2000-01-10 2003-04-29 Maxygen Holdings Ltd. G-CSF conjugates
US6646110B2 (en) 2000-01-10 2003-11-11 Maxygen Holdings Ltd. G-CSF polypeptides and conjugates
US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
PL371781A1 (en) 2001-07-11 2005-06-27 Maxygen Holdings, Ltd. G-csf conjugates
WO2004020462A1 (ja) 2002-08-27 2004-03-11 Fujii, Nobutaka Ｃｘｃｒ４拮抗薬およびその用途
ES2558303T3 (es) 2002-09-11 2016-02-03 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
US7785601B2 (en) 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7695723B2 (en) 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
EP1888119B1 (en) 2005-06-01 2011-03-09 Maxygen, Inc. Pegylated g-csf polypeptides and methods of producing same
DE102005033250A1 (de) † 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
CA2673719C (en) 2006-12-21 2018-07-24 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery
US9155780B2 (en) 2009-02-11 2015-10-13 Yeda Research And Development Co. Ltd. Short beta-defensin-derived peptides
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
IL274572B2 (en) 2015-07-16 2024-01-01 Biolinerx Ltd Compositions and methods for treating cancer
CN109310733A (zh) 2016-02-23 2019-02-05 百欧林纳克斯有限公司 治疗急性骨髓性白血病的方法

Also Published As

Publication number Publication date
DE68918331D1 (de) 1994-10-27
EP0344796A2 (en) 1989-12-06
ATE111921T1 (de) 1994-10-15
DE68918331T2 (de) 1995-05-18
EP0344796B1 (en) 1994-09-21
EP0344796A3 (en) 1990-09-26

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