ES2064349T3 - Inmunoglobulinas humanas especificas del antigeno relacionado con el cancer e hibridomas humanos-humanos que pueden producir estas inmunoglobulinas humanas. - Google Patents

Inmunoglobulinas humanas especificas del antigeno relacionado con el cancer e hibridomas humanos-humanos que pueden producir estas inmunoglobulinas humanas.

Info

Publication number
ES2064349T3
ES2064349T3 ES88304654T ES88304654T ES2064349T3 ES 2064349 T3 ES2064349 T3 ES 2064349T3 ES 88304654 T ES88304654 T ES 88304654T ES 88304654 T ES88304654 T ES 88304654T ES 2064349 T3 ES2064349 T3 ES 2064349T3
Authority
ES
Spain
Prior art keywords
human
immunoglobulins
produce
patient
faced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88304654T
Other languages
English (en)
Inventor
Hideaki Hagiwara
Junzo Nagao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2064349T3 publication Critical patent/ES2064349T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/861—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgG3, IgG4, IgA, or IgY

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

UN NUEVO CLON DE CELULA FUSIONADO HUMANO/HUMANO DERIVADO DE CELULAS B HUMANAS CON LA CAPACIDAD DE PRODUCIR INMUNOGLOBULINAS Y CELULAS B HUMANAS QUE HAN PERDIDO LA CAPACIDAD DE PRODUCIR INMUNOGLOBULINAS, INMUNOGLOBULINAS HUMANAS, ANTIGENO ESPECIFICO PRODUCIDO POR EL CLON DE CELULA FUSIONADO HUMANO/HUMANO Y UN METODO PARA PRODUCIR INMUNOGLOBULINAS HUMANAS. MAS ESPECIALMENTE, UN HIBRIDOMA HUMANO/HUMANO CON CAPACIDAD PARA PRODUCIR INMUNOGLOBULINAS HUMANAS ANTIGENO ESPECIFICO, QUE ES UNA CEPA CELULAR FUSIONADA HUMANO/HUMANO DERIVADA DE CELULAS B HUMANAS DE UN PACIENTE QUE PADECE CANCER DE HIGADO Y UN SUBCLON DE UNA CEPA DE CELULA DE LINFOBLASTO HUMANO Y UNAS INMUNOGLOBULINAS HUMANAS ANTIGENO ESPECIFICAS PRODUCIDAS POR LA CEPA DE CELULA FUSIONADA HUMANO/HUMANO.
ES88304654T 1987-05-23 1988-05-23 Inmunoglobulinas humanas especificas del antigeno relacionado con el cancer e hibridomas humanos-humanos que pueden producir estas inmunoglobulinas humanas. Expired - Lifetime ES2064349T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62126687A JPH0798000B2 (ja) 1987-05-23 1987-05-23 ガン関連抗原特異的ヒト免疫グロブリン

Publications (1)

Publication Number Publication Date
ES2064349T3 true ES2064349T3 (es) 1995-02-01

Family

ID=14941365

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88304654T Expired - Lifetime ES2064349T3 (es) 1987-05-23 1988-05-23 Inmunoglobulinas humanas especificas del antigeno relacionado con el cancer e hibridomas humanos-humanos que pueden producir estas inmunoglobulinas humanas.

Country Status (9)

Country Link
US (1) US5093261A (es)
EP (1) EP0293155B1 (es)
JP (1) JPH0798000B2 (es)
KR (1) KR930012104B1 (es)
AU (1) AU628288B2 (es)
CA (1) CA1340880C (es)
DE (1) DE3851571T2 (es)
ES (1) ES2064349T3 (es)
IL (1) IL86457A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223842B1 (en) 1986-08-11 2007-05-29 Massachusetts Eye And Ear Infirmary Detection of proteins whose absence is associated with a neoplasm
US7384735B1 (en) 1986-08-11 2008-06-10 Massachusetts Eye And Ear Infirmary Retinoblastoma nucleic acids
JPH0798000B2 (ja) * 1987-05-23 1995-10-25 萩原 義秀 ガン関連抗原特異的ヒト免疫グロブリン
US6787153B1 (en) 1991-06-28 2004-09-07 Mitsubishi Chemical Corporation Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
CA2072249C (en) * 1991-06-28 2003-06-17 Saiko Hosokawa Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
US6197582B1 (en) * 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
US7060802B1 (en) * 2000-09-18 2006-06-13 The Trustees Of Columbia University In The City Of New York Tumor-associated marker
AUPR177400A0 (en) * 2000-11-29 2000-12-21 Cancerprobe Pty Ltd Probes for identifying cancer-specific antigens
TW200303919A (en) 2001-12-05 2003-09-16 Hiroyuki Ohno Cytotoxic protein and the use
DE10311248A1 (de) * 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
US20060141482A1 (en) * 2004-12-23 2006-06-29 Awdalla Essam T Method and multicomponent conjugates for treating cancer
US20070178104A1 (en) * 2006-01-31 2007-08-02 Awdalla Essam T Methods and means for treating solid tumors
US20070178107A1 (en) * 2006-01-31 2007-08-02 Awdalla Essam T Method and means for treating solid tumors
US20070179105A1 (en) * 2006-01-31 2007-08-02 Awdalla Essam T Method and means for treating solid tumors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59137497A (ja) * 1983-01-20 1984-08-07 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア 抗原特異的免疫グロブリン生産性ヒト／ヒトハイブリド−マ及びその生産する抗体
US4618577A (en) * 1983-02-09 1986-10-21 The Regents Of The University Of California Human-human hybridoma, CLNH5
JPS6058093A (ja) * 1983-09-12 1985-04-04 Asahi Chem Ind Co Ltd 抗癌ヒト抗体の産生方法
JPS6115897A (ja) * 1984-06-29 1986-01-23 Suntory Ltd ヒト肝癌細胞を特異的に認識するモノクロ−ナル抗体
JPS6144900A (ja) * 1984-08-08 1986-03-04 Green Cross Corp:The モノクロ−ナル抗体及び癌抗原検出用試薬
US4761377A (en) * 1984-10-15 1988-08-02 The Regents Of The University Of California Human-human hybrid cell lines that produce antibodies against antigenic determinants on cancer cells
US4693975A (en) * 1984-11-20 1987-09-15 The Wistar Institute Human hybridroma fusion partner for production of human monoclonal antibodies
EP0222360A3 (en) * 1985-11-12 1989-03-15 Biotherapeutics Inc. A method of producing a patient-specific cytotoxic reagent and composition
JPH0798000B2 (ja) * 1987-05-23 1995-10-25 萩原 義秀 ガン関連抗原特異的ヒト免疫グロブリン
US4942123A (en) * 1987-09-17 1990-07-17 The Regents Of The University Of California ppRB110 -phosphoprotein the retinoblastoma susceptibility gene product
US5536571A (en) * 1993-07-02 1996-07-16 Congoleum Corporation Release coating

Also Published As

Publication number Publication date
CA1340880C (en) 2000-01-25
EP0293155A2 (en) 1988-11-30
EP0293155B1 (en) 1994-09-21
EP0293155A3 (en) 1989-07-12
KR930012104B1 (ko) 1993-12-24
US5093261A (en) 1992-03-03
DE3851571T2 (de) 1995-03-09
IL86457A0 (en) 1988-11-15
KR880014109A (ko) 1988-12-22
JPH0798000B2 (ja) 1995-10-25
AU628288B2 (en) 1992-09-17
JPS63290898A (ja) 1988-11-28
AU1654588A (en) 1989-11-23
DE3851571D1 (de) 1994-10-27
IL86457A (en) 1994-07-31

Similar Documents

Publication Publication Date Title
DK154087C (da) Monoklonalt antistof, fremstilling heraf, hybrodimacellelinie til anvendelse ved fremstilling heraf, fremgangsmaade til anvendelse heraf samt diagnostisk praeparat indeholdende antistoffet
DK154769C (da) Monoklonalt antistof, fremstilling heraf, hybridomacellelinie til anvendelse ved fremstilling heraf samt fremgangsmaader til anvendelse heraf
DK154092C (da) Fremgangsmaade til fremstilling af et monoklonalt antistof, hybridomacellelinie til anvendelse ved fremgangsmaaden samt fremgangsmaade til diagnose og diagnostisk praeparat med det fremstillede monoklonale antistof
NO803658L (no) Hybridcellelinje for fremstilling av komplementfikserende monoklonalt antistoff til humane undertrykker t-celler, selve antistoffet og fremgangsmaater for dets fremstilling
DK153954C (da) Fremgangsmaade til fremstilling af et monoklonalt antistof, hybridomacellelinie til anvendelse ved fremgangsmaaden samt fremgangsmaade til diagnose og diagnostisk praeparat med det fremstillede monoklonale antistof
FI840219A0 (fi) Human-humanhybridom foer neoplasmer
ATE58554T1 (de) Menschlicher hybridomfusionspartner zur herstellung menschlicher monoklonaler antikoerper.
DK154093C (da) Fremgangsmaade til fremstilling af et monoklonalt antistof, hybridomacellelinie til anvendelse ved fremgangsmaaden samt diagnostisk praeparat med det fremstillede monoklonale antistof
DK153891C (da) Fremgangsmaade til fremstilling af et monoklonalt antistof, hybridomacellelinie til anvendelse ved fremgangsmaaden samt fremgangsmaade til diagnose og diagnostisk praeparat med det fremstillede monoklonale antistof
ES8200559A1 (es) Un anticuerpo monoclonal
DK154090C (da) Fremgangsmaade til fremstilling af et monoklonalt antistof, hybridomacellelinie til anvendelse ved fremgangsmaaden samt fremgangsmaade til diagnose under anvendelse af det fremstillede monoklonale antistof
ES8707114A1 (es) Procedimiento para la obtencion de un anticuerpo monoclonal anti-alfa-amilasa
ES8707296A1 (es) Un metodo para producir anticuerpos monoclonales humanos
EP0255367A3 (en) Cancer cell specific monoclonal antibodies and corresponding hybridomas, and their preparation and use

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 293155

Country of ref document: ES