ES2065678T3 - Procedimiento para la preparacion de derivados de uracilo. - Google Patents

Procedimiento para la preparacion de derivados de uracilo.

Info

Publication number
ES2065678T3
ES2065678T3 ES91904039T ES91904039T ES2065678T3 ES 2065678 T3 ES2065678 T3 ES 2065678T3 ES 91904039 T ES91904039 T ES 91904039T ES 91904039 T ES91904039 T ES 91904039T ES 2065678 T3 ES2065678 T3 ES 2065678T3
Authority
ES
Spain
Prior art keywords
preparation
uracilo
derivatives
procedure
conves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91904039T
Other languages
English (en)
Inventor
Angelo Bedeschi
Walter Cabri
Ilaria Candiani
Tiziano Martinengo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of ES2065678T3 publication Critical patent/ES2065678T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN NUEVO PROCESO PARA LA PREPARACION DE DERIVADOS DE URACILO UTILES COMO INTERMEDIARIOS EN LA SINTESIS DE URIDINAS QUE TIENEN ACTIVIDAD ANTIVIRICA O ANTITUMORAL O UTILES COMO COADYUVANTES EN TERAPIA VIRICA, CARACTERIZADA POR LA CONVERSION DE UN COMPUESTO DE FORMULA (II) EN SU DERIVADO DE MESILATO DE FORMULA (III) QUE ES REDUCIDO PARA DAR EL COMPUESTO DESEADO DE FORMULA (I), EN LA QUE R1 ES H, HALOGENO, ALKILO, ARILO O ARALKILO.
ES91904039T 1990-02-22 1991-02-21 Procedimiento para la preparacion de derivados de uracilo. Expired - Lifetime ES2065678T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909004021A GB9004021D0 (en) 1990-02-22 1990-02-22 Process for preparing uracil derivatives

Publications (1)

Publication Number Publication Date
ES2065678T3 true ES2065678T3 (es) 1995-02-16

Family

ID=10671447

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91904039T Expired - Lifetime ES2065678T3 (es) 1990-02-22 1991-02-21 Procedimiento para la preparacion de derivados de uracilo.

Country Status (20)

Country Link
US (1) US5286861A (es)
EP (1) EP0515464B1 (es)
JP (1) JPH05504148A (es)
KR (1) KR927003541A (es)
AT (1) ATE113038T1 (es)
AU (1) AU647082B2 (es)
CA (1) CA2076369A1 (es)
DE (1) DE69104710T2 (es)
DK (1) DK0515464T3 (es)
ES (1) ES2065678T3 (es)
FI (1) FI923716A0 (es)
GB (1) GB9004021D0 (es)
HU (1) HU209623B (es)
IE (1) IE910594A1 (es)
IL (1) IL97066A (es)
MY (1) MY105291A (es)
NZ (1) NZ237143A (es)
PT (1) PT96832A (es)
WO (1) WO1991013064A1 (es)
ZA (1) ZA911253B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6366426B2 (ja) * 2014-03-05 2018-08-01 富士フイルム株式会社 偏光板用組成物、偏光板保護フィルム、偏光子、偏光板、液晶表示装置およびこれに用いる化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1250829B (es) *
US4618604A (en) * 1983-09-26 1986-10-21 Monsanto Company Composition and method for improving feed utilization or tissue production in animals
US4613604A (en) * 1985-07-31 1986-09-23 Brown University Research Foundation Hydroxymethyl derivatives of 5-benzylacyclouridine and 5-benzoyloxybenzylacyclouridine and their use as potentiators for 5-fluoro-2'-deoxyuridine

Also Published As

Publication number Publication date
ATE113038T1 (de) 1994-11-15
FI923716A7 (fi) 1992-08-19
CA2076369A1 (en) 1991-08-23
GB9004021D0 (en) 1990-04-18
AU7244091A (en) 1991-09-18
DE69104710T2 (de) 1995-03-23
DK0515464T3 (da) 1994-11-14
US5286861A (en) 1994-02-15
HUT62867A (en) 1993-06-28
MY105291A (en) 1994-09-30
PT96832A (pt) 1991-10-31
IL97066A (en) 1995-03-30
KR927003541A (ko) 1992-12-18
HU9202679D0 (en) 1992-12-28
JPH05504148A (ja) 1993-07-01
EP0515464A1 (en) 1992-12-02
ZA911253B (en) 1991-11-27
IL97066A0 (en) 1992-03-29
AU647082B2 (en) 1994-03-17
HU209623B (en) 1994-09-28
WO1991013064A1 (en) 1991-09-05
DE69104710D1 (de) 1994-11-24
IE910594A1 (en) 1991-08-28
EP0515464B1 (en) 1994-10-19
FI923716A0 (fi) 1992-08-19
NZ237143A (en) 1992-05-26

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