ES2065932T3 - Anticuerpo monoclonal contra pseudomonas aeruginosa, su preparacion y empleo. - Google Patents

Anticuerpo monoclonal contra pseudomonas aeruginosa, su preparacion y empleo.

Info

Publication number
ES2065932T3
ES2065932T3 ES89106463T ES89106463T ES2065932T3 ES 2065932 T3 ES2065932 T3 ES 2065932T3 ES 89106463 T ES89106463 T ES 89106463T ES 89106463 T ES89106463 T ES 89106463T ES 2065932 T3 ES2065932 T3 ES 2065932T3
Authority
ES
Spain
Prior art keywords
aeruginous
pseudomonas
monoclonal antibody
employment
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89106463T
Other languages
English (en)
Inventor
Horst Dr Domdey
Matthias Marget
Specht Bernd-Ulrich Prof D Von
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2065932T3 publication Critical patent/ES2065932T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE DESCRIBE UN ANTICUERPO MONOCLONAL (ACM) QUE TIENE REACCION CRUZADA CON LOS 19 SEROTIPOS DE PSEUDOMONAS AERUGINOSA CONOCIDOS HASTA AHORA. SE DA LA SECUENCIA DE LAS REGIONES VARIABLES. ESTE MAC SE PUEDE APLICAR COMO MEDIO DE DIAGNOSTICO, COMO PRINCIPIO ACTIVO O COMO PORTADOR DE PRINCIPIOS ACTIVOS.
ES89106463T 1988-04-19 1989-04-12 Anticuerpo monoclonal contra pseudomonas aeruginosa, su preparacion y empleo. Expired - Lifetime ES2065932T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3813023A DE3813023A1 (de) 1988-04-19 1988-04-19 Monoklonaler antikoerper gegen pseudomonas aeruginosa, seine herstellung und verwendung

Publications (1)

Publication Number Publication Date
ES2065932T3 true ES2065932T3 (es) 1995-03-01

Family

ID=6352325

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89106463T Expired - Lifetime ES2065932T3 (es) 1988-04-19 1989-04-12 Anticuerpo monoclonal contra pseudomonas aeruginosa, su preparacion y empleo.

Country Status (10)

Country Link
EP (1) EP0338395B1 (es)
JP (1) JPH0213376A (es)
KR (1) KR890016165A (es)
AT (1) ATE116374T1 (es)
AU (1) AU622446B2 (es)
DE (2) DE3813023A1 (es)
DK (1) DK186289A (es)
ES (1) ES2065932T3 (es)
FI (1) FI891816L (es)
PT (1) PT90296B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0329196A (ja) * 1989-05-09 1991-02-07 Advanced Micro Devicds Inc センス増幅器
CA2038978A1 (en) * 1990-04-06 1991-10-07 Richard P. Darveau Antibodies for the treatment and diagnosis of pseudomonas aeruginosa infections
KR20080068048A (ko) * 2005-10-28 2008-07-22 메이지 세이카 가부시키가이샤 녹농균의 외막 단백질 ｐａ5158
WO2009064944A2 (en) * 2007-11-16 2009-05-22 Nuvelo, Inc. Antibodies to lrp6
MA34287B1 (fr) 2010-05-06 2013-06-01 Novartis Ag Compositions et méthodes d'utilisation d'anticorps multivalents thérapeutiques de faible densité de la protéine apparentée à la lipoprotéine 6 (lrp6)
WO2011138392A1 (en) 2010-05-06 2011-11-10 Novartis Ag Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
WO2013067355A1 (en) 2011-11-04 2013-05-10 Novartis Ag Low density lipoprotein-related protein 6 (lrp6) - half life extender constructs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256713A3 (en) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutic human antipseudomonas aeruginosa antibodies
JPS63267295A (ja) * 1986-12-03 1988-11-04 Sumitomo Chem Co Ltd ヒト抗体、抗体遺伝子及び対応する組換え体
US4870161A (en) * 1987-09-25 1989-09-26 The United States Of America As Represented By The Department Of Health And Human Services Reagents and probes for distinguishing and isolating different GTP-binding proteins
DK8189A (da) * 1988-01-12 1989-07-13 Bunge Australia Antigen-antistof-konjugater, deres fremstilling og anvendelse
WO1990012088A1 (en) * 1989-04-13 1990-10-18 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce MONOCLONAL ANTIBODIES TO HUMAN GLUTATHIONE S TRANSFERASE Pi

Also Published As

Publication number Publication date
EP0338395B1 (de) 1994-12-28
KR890016165A (ko) 1989-11-28
PT90296A (pt) 1989-11-10
FI891816A7 (fi) 1989-10-20
DK186289A (da) 1989-12-18
JPH0213376A (ja) 1990-01-17
AU622446B2 (en) 1992-04-09
FI891816A0 (fi) 1989-04-17
ATE116374T1 (de) 1995-01-15
DE58908815D1 (de) 1995-02-09
DE3813023A1 (de) 1989-11-16
PT90296B (pt) 1995-01-31
EP0338395A2 (de) 1989-10-25
AU3310189A (en) 1989-10-26
DK186289D0 (da) 1989-04-18
FI891816L (fi) 1989-10-20
EP0338395A3 (en) 1990-03-28

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