ES2066447T3 - Derivados de piridopiracina para tratar abuso y adiccion a substancias. - Google Patents

Derivados de piridopiracina para tratar abuso y adiccion a substancias.

Info

Publication number
ES2066447T3
ES2066447T3 ES91910566T ES91910566T ES2066447T3 ES 2066447 T3 ES2066447 T3 ES 2066447T3 ES 91910566 T ES91910566 T ES 91910566T ES 91910566 T ES91910566 T ES 91910566T ES 2066447 T3 ES2066447 T3 ES 2066447T3
Authority
ES
Spain
Prior art keywords
addiction
derivatives
piridopiracina
substance abuse
treat substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91910566T
Other languages
English (en)
Inventor
Gene Michael Bright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2066447T3 publication Critical patent/ES2066447T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE PRESENTAN DERIVADOS RACEMICOS U OPTICOS ACTIVOS DE LA PIRIDO[1, 2-A] PIRACINA D ELA FORMULA (I) EN DONDE X ES N O CH E Y REPRESENTA UNO O VARIOS RADICALES PIRAZOLO, TRIAZOLO, TETRAZOLO, O DE IMIDO CICLICO; LOS DERIVADOS SON UTILES EN EL TRATAMIENTO DEL ABUSO Y / O LA ADICION A SUBSTANCIAS TALES COMO NARCOTICOS, ALCOHOL O NICOTINA.
ES91910566T 1990-06-29 1991-05-28 Derivados de piridopiracina para tratar abuso y adiccion a substancias. Expired - Lifetime ES2066447T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/003708 WO1992000075A1 (en) 1990-06-29 1990-06-29 Pyridopyrazine derivatives for treating substance abuse and addiction

Publications (1)

Publication Number Publication Date
ES2066447T3 true ES2066447T3 (es) 1995-03-01

Family

ID=22220931

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91910566T Expired - Lifetime ES2066447T3 (es) 1990-06-29 1991-05-28 Derivados de piridopiracina para tratar abuso y adiccion a substancias.

Country Status (17)

Country Link
US (1) US5616585A (es)
EP (1) EP0536173B1 (es)
JP (1) JPH05507274A (es)
KR (1) KR930701171A (es)
AT (1) ATE116545T1 (es)
AU (1) AU651977B2 (es)
CA (1) CA2086335C (es)
DE (1) DE69106516T2 (es)
DK (1) DK0536173T3 (es)
ES (1) ES2066447T3 (es)
HU (1) HUT62797A (es)
IE (1) IE64467B1 (es)
IL (1) IL98588A (es)
MY (1) MY106553A (es)
NZ (1) NZ238750A (es)
WO (2) WO1992000075A1 (es)
ZA (1) ZA915012B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
HN1999000146A (es) * 1998-09-21 2000-11-11 Pfizer Prod Inc Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.
EP1177792A3 (en) * 2000-07-27 2002-10-23 Pfizer Products Inc. Dopamine D4 Ligands for the treatment of novelty-seeking disorders
UA110688C2 (uk) 2012-09-21 2016-01-25 Пфайзер Інк. Біциклічні піридинони
KR102000382B1 (ko) 2015-02-03 2019-07-15 화이자 인코포레이티드 신규 시클로프로파벤조푸라닐 피리도피라진디온

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK144213C (da) * 1979-06-20 1982-06-21 H B Nielsen Hylster til garnspole
US4777173A (en) * 1987-03-25 1988-10-11 Bristol-Myers Company Method for treatment of alcohol abuse
DE3727879A1 (de) * 1987-08-21 1989-03-02 Troponwerke Gmbh & Co Kg Verwendung von 2-pyrimidinyl-1-piperazin-derivaten
DE3736974A1 (de) * 1987-10-31 1989-05-11 Troponwerke Gmbh & Co Kg Verwendung von 2-pyrimidinyl-1-piperazin-derivaten
IL91451A0 (en) * 1988-08-30 1990-04-29 Bristol Myers Co Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents

Also Published As

Publication number Publication date
DE69106516D1 (de) 1995-02-16
EP0536173B1 (en) 1995-01-04
WO1992000074A3 (en) 1992-03-05
ZA915012B (en) 1993-02-24
AU7909491A (en) 1992-01-23
EP0536173A1 (en) 1993-04-14
CA2086335C (en) 1996-01-02
DE69106516T2 (de) 1995-05-11
IL98588A0 (en) 1992-07-15
AU651977B2 (en) 1994-08-11
IL98588A (en) 1995-06-29
KR930701171A (ko) 1993-06-11
MY106553A (en) 1995-06-30
HUT62797A (en) 1993-06-28
DK0536173T3 (da) 1995-05-01
IE912259A1 (en) 1992-01-01
WO1992000074A2 (en) 1992-01-09
JPH05507274A (ja) 1993-10-21
IE64467B1 (en) 1995-08-09
NZ238750A (en) 1999-09-29
US5616585A (en) 1997-04-01
WO1992000075A1 (en) 1992-01-09
CA2086335A1 (en) 1991-12-30
HU9204138D0 (en) 1993-04-28
ATE116545T1 (de) 1995-01-15

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