ES2069809T3 - Procedimiento para la preparacion de acido dimetilciclopropanocarboxilico. - Google Patents

Procedimiento para la preparacion de acido dimetilciclopropanocarboxilico.

Info

Publication number
ES2069809T3
ES2069809T3 ES91121549T ES91121549T ES2069809T3 ES 2069809 T3 ES2069809 T3 ES 2069809T3 ES 91121549 T ES91121549 T ES 91121549T ES 91121549 T ES91121549 T ES 91121549T ES 2069809 T3 ES2069809 T3 ES 2069809T3
Authority
ES
Spain
Prior art keywords
preparation
acid
dimetilciclopropanocarboxilico
procedure
dimethylcyclopropanecarboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91121549T
Other languages
English (en)
Inventor
Thomas Dr Meul
Ulrich Dr Kampfen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2069809T3 publication Critical patent/ES2069809T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UN NUEVO METODO PARA LA ELABORACION DE ACIDO DE CARBONO R, S-2, 2-DIMETILCICLOPROPANO, PARTIENDO DE OXIDO DE ISOBUTILENO Y PHOSPHONOESSIGSAURETRIALKYLESTER. EN PRIMER LUGAR SE FORMA EL ACIDO DE CARBONO DE R, S-2, 2-DIMETILCICLOPROPANO-C SUB 1-C SUB 4 ESTER DE ALQUILO, QUE DESPUES SE HIDROLIZA EN UN ACIDO CORRESPONDIENTE. EL ACIDO DE CARBONO R, S-2,2DIMETICICLOPROPANO ES UN PRODUCTO INTERMEDIO IMPORTANTE QUE SIRVE PARA LA ELABORACION DE S-(+)2,2 -DIMETILCICLOPROPANOCARBOXAMID.
ES91121549T 1990-12-17 1991-12-16 Procedimiento para la preparacion de acido dimetilciclopropanocarboxilico. Expired - Lifetime ES2069809T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH399190 1990-12-17

Publications (1)

Publication Number Publication Date
ES2069809T3 true ES2069809T3 (es) 1995-05-16

Family

ID=4267768

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91121549T Expired - Lifetime ES2069809T3 (es) 1990-12-17 1991-12-16 Procedimiento para la preparacion de acido dimetilciclopropanocarboxilico.

Country Status (9)

Country Link
US (1) US5149869A (es)
EP (1) EP0491330B1 (es)
JP (1) JPH04266844A (es)
AT (1) ATE120178T1 (es)
CA (1) CA2056840A1 (es)
DE (1) DE59105000D1 (es)
DK (1) DK0491330T3 (es)
ES (1) ES2069809T3 (es)
NO (1) NO175588C (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE172248T1 (de) * 1991-07-26 1998-10-15 Lonza Ag Gentechnologisches verfahren zur herstellung von s-(+)-2,2-dimethylcyclopropancarboxamid mittels mikroorganismen
MXPA03010547A (es) * 2001-05-18 2004-05-27 Ranbaxy Lab Ltd Proceso para la preparacion de cilastatina sodica amorfa.
GB0615620D0 (en) * 2006-08-05 2006-09-13 Astrazeneca Ab A process for the preparation of optically active intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2751133A1 (de) * 1977-11-16 1979-05-17 Degussa Verfahren zum cyclisieren von gamma-chlorcarbonsaeureestern
EP0048301A1 (en) * 1980-09-24 1982-03-31 Merck & Co. Inc. 2-(Cyclopropane-carboxamido)-2-alkenoic acids, their esters and salts, and antibacterial compositions comprising the same and a thienamycin-type compound
US4542235A (en) * 1982-04-12 1985-09-17 Sumitomo Chemical Company, Limited Method for producing an optically active 2,2-dimethylcyclopropanecarboxylic acid

Also Published As

Publication number Publication date
DE59105000D1 (de) 1995-04-27
DK0491330T3 (da) 1995-04-18
ATE120178T1 (de) 1995-04-15
JPH04266844A (ja) 1992-09-22
EP0491330B1 (de) 1995-03-22
NO175588B (no) 1994-07-25
NO175588C (no) 1994-11-02
US5149869A (en) 1992-09-22
EP0491330A1 (de) 1992-06-24
CA2056840A1 (en) 1992-06-18
NO914965D0 (no) 1991-12-16
NO914965L (no) 1992-06-18

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