ES2070837T3 - Nuevas formulaciones de liberacion controlada de compuestos de tetraciclina. - Google Patents

Nuevas formulaciones de liberacion controlada de compuestos de tetraciclina.

Info

Publication number
ES2070837T3
ES2070837T3 ES88114235T ES88114235T ES2070837T3 ES 2070837 T3 ES2070837 T3 ES 2070837T3 ES 88114235 T ES88114235 T ES 88114235T ES 88114235 T ES88114235 T ES 88114235T ES 2070837 T3 ES2070837 T3 ES 2070837T3
Authority
ES
Spain
Prior art keywords
compounds
tetracicline
controlled release
new formulations
demetiltetracicline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88114235T
Other languages
English (en)
Inventor
Joseph J Valerose Jr
Raymond J Biehl
Nitin V Sheth
Walter A Strathy
Michael Kay Doelling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22303124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2070837(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2070837T3 publication Critical patent/ES2070837T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE PRESENTAN COMPUESTOS FARMACEUTICOS QUE COMPRENDEN GRANULOS ESFERICOS QUE INCLUYEN SOBRE LOS MISMOS O EN SU INTERIOR UN 7 - O 9 - ALKILAMINO - 6 DEOXI - 6 DEMETILTETRACICLINA O UN ACIDO DEL MISMO MEZCLADA CON AL MENOS UN ESCIPIENTE. ESTOS COMPUESTOS ESTAN ADAPTADOS PARA CONTROLAR LA CANTIDAD DE MEDICAMENTE LIBERADO EN EL ESTOMAGO Y EN EL INTESTINO Y PARA EVITAR QUE SE PRODUZCAN NAUSEAS DESPUES DE LA ADMINISTRACION ORAL DURANTE LA TERAPIA ANTIBACTERIAL.
ES88114235T 1987-10-06 1988-09-01 Nuevas formulaciones de liberacion controlada de compuestos de tetraciclina. Expired - Lifetime ES2070837T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/104,917 US4837030A (en) 1987-10-06 1987-10-06 Novel controlled release formulations of tetracycline compounds

Publications (1)

Publication Number Publication Date
ES2070837T3 true ES2070837T3 (es) 1995-06-16

Family

ID=22303124

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88114235T Expired - Lifetime ES2070837T3 (es) 1987-10-06 1988-09-01 Nuevas formulaciones de liberacion controlada de compuestos de tetraciclina.

Country Status (24)

Country Link
US (1) US4837030A (es)
EP (1) EP0310814B1 (es)
JP (1) JP2771189B2 (es)
KR (1) KR970007902B1 (es)
AR (1) AR243077A1 (es)
AT (1) ATE120957T1 (es)
AU (1) AU609525B2 (es)
CA (1) CA1338439C (es)
CZ (1) CZ279809B6 (es)
DE (1) DE3853566T2 (es)
DK (1) DK175578B1 (es)
ES (1) ES2070837T3 (es)
FI (1) FI97862C (es)
GR (1) GR3015767T3 (es)
HK (1) HK1000313A1 (es)
HU (1) HU202110B (es)
IL (1) IL87699A (es)
NO (1) NO175619C (es)
NZ (1) NZ226396A (es)
PH (1) PH27236A (es)
PL (1) PL275089A1 (es)
PT (1) PT88664B (es)
SK (1) SK656388A3 (es)
ZA (1) ZA887478B (es)

Families Citing this family (56)

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EP0281200B1 (en) * 1987-03-02 1994-01-19 Yamanouchi Europe B.V. Pharmaceutical composition, pharmaceutical granulate and process for their preparation
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
US5277916A (en) * 1988-02-01 1994-01-11 F. H. Faulding & Co., Ltd. Tetracycline dosage form
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
EP0418597A3 (en) * 1989-09-21 1991-11-27 American Cyanamid Company Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
ATE114472T1 (de) * 1989-09-21 1994-12-15 American Cyanamid Co System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
WO1993012768A1 (en) * 1991-12-30 1993-07-08 Fmc Corporation Microcrystalline cellulose spheronization composition
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline
US5614223A (en) * 1992-05-04 1997-03-25 Digestive Care Inc. Intraoral medicament-releasing device
CA2093282C (en) * 1992-05-04 1999-01-12 Tibor Sipos Intraoral medicament-releasing device
US6224911B1 (en) * 1993-03-16 2001-05-01 Syntex (U.S.A.) Llc Process for the preparation of enteric coated pharmaceutical dosage forms
US5536507A (en) * 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
US20060068017A1 (en) * 1996-03-25 2006-03-30 Wyeth Extended release formulation
US20030215507A1 (en) * 1996-03-25 2003-11-20 Wyeth Extended release formulation
US6230052B1 (en) 1999-01-29 2001-05-08 Andy Wolff Device and method for stimulating salivation
AU5139600A (en) * 1999-05-27 2000-12-18 Drugtech Corporation Nutritional formulations
US20050037065A1 (en) * 1999-05-27 2005-02-17 Drugtech Corporation Nutritional formulations
US6858725B1 (en) 1999-11-12 2005-02-22 R.P. Scherer Technologies, Inc. Microcrystalline cellulose cushioning granules
EP2311440A1 (en) * 2001-04-05 2011-04-20 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
AU2002358270A1 (en) * 2001-12-20 2003-07-09 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
AU2003213876B2 (en) * 2002-04-12 2006-10-12 Mayne Pharma International Pty Ltd An improved modified release preparation
AUPS167602A0 (en) * 2002-04-12 2002-05-16 F.H. Faulding & Co. Limited An improved modified release preparation
US6958161B2 (en) * 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
AU2003284942A1 (en) * 2002-10-30 2004-06-07 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
WO2004091483A2 (en) 2003-04-07 2004-10-28 Shire Laboratories, Inc. Once daily formulations of tetracyclines
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
AU2006206359B2 (en) * 2005-01-21 2011-03-31 Allergan Pharmaceuticals International Limited A tetracycline metal complex in a solid dosage form
CN101115409B (zh) * 2005-02-04 2013-03-27 菲利普莫里斯生产公司 具有纤维质滋味添加剂的香烟及过滤嘴
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
BRPI0620646A2 (pt) * 2005-12-22 2011-11-22 Wyeth Corp composição farmacêutica compreendendo tigeciclina e seu uso
US20070166273A1 (en) * 2006-01-19 2007-07-19 Krivulka Joseph J Skin treatment educational kit
JP5527921B2 (ja) * 2006-12-22 2014-06-25 エスエス製薬株式会社 苦味を隠蔽した経口固形組成物
ITMI20070022A1 (it) 2007-01-09 2008-07-10 I P S Internat Products & Services Srl Formulazione di prodotti solidi a rilascio controllato per uso orale in bustine monodose e relativo procedimento di preparazione
KR20130137696A (ko) * 2007-03-23 2013-12-17 몰레큘러 리서치 센터, 인크. 테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
PT2271348T (pt) * 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
WO2010017310A1 (en) * 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
WO2013122260A1 (en) * 2012-02-15 2013-08-22 Takeda Pharmaceutical Company Limited Tablet
HUE046754T2 (hu) 2013-03-15 2020-03-30 Braintree Laboratories Inc Kettõs felhasználású orális gyógyszer kompozíció tabletták szulfát sókból és eljárás ezek alkalmazására
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
US11103517B2 (en) 2015-04-07 2021-08-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline
IL273038B (en) 2020-03-03 2022-02-01 Ben Zion Karmon bone graft

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CH434571A (de) * 1966-07-05 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung von Antibiotika mit verlängerter therapeutischer Wirkung
CH434240A (de) * 1965-12-30 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung einer therapeutischen Tetracyclinzubereitung mit verlängerter therapeutischer Wirkung
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Also Published As

Publication number Publication date
HUT50046A (en) 1989-12-28
FI884575A0 (fi) 1988-10-05
DK556788D0 (da) 1988-10-05
EP0310814B1 (en) 1995-04-12
GR3015767T3 (en) 1995-07-31
PH27236A (en) 1993-05-04
EP0310814A3 (en) 1989-05-03
FI97862B (fi) 1996-11-29
FI97862C (fi) 1997-03-10
IL87699A0 (en) 1989-02-28
KR890006242A (ko) 1989-06-12
NO175619B (es) 1994-08-01
AR243077A1 (es) 1993-07-30
NO884408L (no) 1989-04-07
JP2771189B2 (ja) 1998-07-02
CA1338439C (en) 1996-07-09
FI884575L (fi) 1989-04-07
AU609525B2 (en) 1991-05-02
IL87699A (en) 1994-06-24
NO175619C (no) 1994-11-09
PL275089A1 (en) 1989-07-10
PT88664B (pt) 2003-06-30
HU202110B (en) 1991-02-28
US4837030A (en) 1989-06-06
PT88664A (pt) 1989-07-31
JPH01128929A (ja) 1989-05-22
KR970007902B1 (ko) 1997-05-17
AU2344488A (en) 1989-04-06
ATE120957T1 (de) 1995-04-15
CZ656388A3 (en) 1995-02-15
DE3853566T2 (de) 1996-01-11
DE3853566D1 (de) 1995-05-18
HK1000313A1 (en) 1998-02-27
SK278567B6 (en) 1997-10-08
NO884408D0 (no) 1988-10-05
EP0310814A2 (en) 1989-04-12
DK175578B1 (da) 2004-12-13
CZ279809B6 (cs) 1995-07-12
DK556788A (da) 1989-04-07
NZ226396A (en) 1991-08-27
SK656388A3 (en) 1997-10-08
ZA887478B (en) 1989-06-28

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