ES2134221T3 - Sistemas mejorados del tipo de una vez al dia de administracion pulsatil de minociclina. - Google Patents

Sistemas mejorados del tipo de una vez al dia de administracion pulsatil de minociclina.

Info

Publication number
ES2134221T3
ES2134221T3 ES93101096T ES93101096T ES2134221T3 ES 2134221 T3 ES2134221 T3 ES 2134221T3 ES 93101096 T ES93101096 T ES 93101096T ES 93101096 T ES93101096 T ES 93101096T ES 2134221 T3 ES2134221 T3 ES 2134221T3
Authority
ES
Spain
Prior art keywords
distribution
minocycline
systems
distributing
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93101096T
Other languages
English (en)
Inventor
Nitin Vadilal Sheth
Joseph James Valorose Jr
Keith Anthony Ellway
Madurai Gurusamy Ganesan
Keiran George Mooney
Jerry Bain Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2134221T3 publication Critical patent/ES2134221T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Treatment Devices (AREA)
  • Laser Surgery Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)

Abstract

SE MUESTRAN SISTEMAS DE DISTRIBUCION FARMACEUTICA QUE CONTIENEN 7 DE ADICION ACIDA NO TOXICA CONSIGUIENTE Y QUE COMPRENDEN MEZCLAS DE UNA PROPORCION MENOR DE GRANULOS ESFERICOS RECUBIERTOS DE POLIMERO MEZCLADO DE DISTRIBUCION LENTA PARA DISTRIBUIR PARTE DE LA MINOCICLINA EN UN MEDIO CON UN PH MENOR DE 3,9 Y EL RESTO ENTRE 4,0 A 7,5 Y UNA PROPORCION MAYOR DE GRANULOS DE DISTRIBUCION RAPIDA NO RECUBIERTOS ADAPTADOS PARA DISTRIBUIR MINOCICLINA EN UN MEDIO CON UN PH INFERIOR A 3,9 Y CAPSULAS EN FORMA DE UNIDAD DE DOSIS ORAL QUE CONTIENEN LOS COMPONENTES ANTERIORES. ESTOS SISTEMAS Y FORMULACIONES OFRECEN NIVELES SANGUINEOS TERAPEUTICOS MEJORADOS DE MINOCICLINA PARA AL MENOS 24 HORAS CUANDO SE ADMINISTRAN A UN SUJETO UNA SOLA VEZ AL DIA, AL MARGEN DE SI EL PACIENTE ES ALIMENTADO O NO. SE OFRECEN TAMBIEN METODOS PARA LA PREPARACION DE LOS SISTEMAS Y FORMULACIONES.
ES93101096T 1992-03-02 1993-01-25 Sistemas mejorados del tipo de una vez al dia de administracion pulsatil de minociclina. Expired - Lifetime ES2134221T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/844,109 US5262173A (en) 1992-03-02 1992-03-02 Pulsatile once-a-day delivery systems for minocycline

Publications (1)

Publication Number Publication Date
ES2134221T3 true ES2134221T3 (es) 1999-10-01

Family

ID=25291839

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93101096T Expired - Lifetime ES2134221T3 (es) 1992-03-02 1993-01-25 Sistemas mejorados del tipo de una vez al dia de administracion pulsatil de minociclina.

Country Status (24)

Country Link
US (2) US5262173A (es)
EP (1) EP0558913B1 (es)
JP (1) JPH069407A (es)
KR (1) KR100270491B1 (es)
CN (1) CN1039194C (es)
AT (1) ATE181504T1 (es)
AU (1) AU656841B2 (es)
CA (1) CA2090561C (es)
CZ (1) CZ283684B6 (es)
DE (1) DE69325402T2 (es)
DK (1) DK0558913T3 (es)
ES (1) ES2134221T3 (es)
FI (1) FI110163B (es)
GR (1) GR3031028T3 (es)
HU (1) HU219580B (es)
IL (1) IL104865A (es)
LV (1) LV12399B (es)
MX (1) MX9300998A (es)
NO (1) NO307170B1 (es)
NZ (1) NZ245951A (es)
PL (1) PL171609B1 (es)
SG (1) SG47785A1 (es)
TW (1) TW299235B (es)
ZA (1) ZA931444B (es)

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AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
WO2002100381A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
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CA2894736C (en) 2003-04-07 2019-07-16 Supernus Pharmaceuticals, Inc. Once daily formulations of tetracyclines
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
JP2008535922A (ja) * 2005-04-12 2008-09-04 エラン・ファルマ・インターナショナル・リミテッド 細菌感染を治療するためのセファロスポリンを含む放出制御組成物
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
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US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
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WO2012145749A1 (en) 2011-04-22 2012-10-26 Napo Pharmaceuticals, Inc. Pharmacologically optimized multimodal drug delivery system for nordihydroguiaretic acid (ndga)
ES2755075T3 (es) 2011-05-05 2020-04-21 Hennig Arzneimittel Gmbh&Co Kg Forma farmacológica para la liberación dirigida de principios activos
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Also Published As

Publication number Publication date
DE69325402D1 (de) 1999-07-29
GR3031028T3 (en) 1999-12-31
IL104865A0 (en) 1993-06-10
CA2090561A1 (en) 1993-09-03
FI930906A0 (fi) 1993-03-01
PL297903A1 (en) 1993-11-15
NO930743L (no) 1993-09-03
US5262173A (en) 1993-11-16
EP0558913A1 (en) 1993-09-08
CZ30093A3 (en) 1994-02-16
FI930906L (fi) 1993-09-03
CN1078889A (zh) 1993-12-01
ATE181504T1 (de) 1999-07-15
IL104865A (en) 1997-02-18
CZ283684B6 (cs) 1998-06-17
TW299235B (es) 1997-03-01
SG47785A1 (en) 1998-04-17
AU3384293A (en) 1993-09-09
NZ245951A (en) 1994-06-27
NO307170B1 (no) 2000-02-21
MX9300998A (es) 1993-09-01
PL171609B1 (pl) 1997-05-30
ZA931444B (en) 1993-10-14
LV12399A (lv) 1999-12-20
CN1039194C (zh) 1998-07-22
DK0558913T3 (da) 1999-12-13
HU219580B (hu) 2001-05-28
LV12399B (en) 2000-06-20
US5348748A (en) 1994-09-20
KR930019209A (ko) 1993-10-18
CA2090561C (en) 2004-10-05
FI110163B (fi) 2002-12-13
NO930743D0 (no) 1993-03-01
DE69325402T2 (de) 2000-02-17
KR100270491B1 (ko) 2000-11-01
HK1009930A1 (en) 1999-06-11
HU9300570D0 (en) 1993-05-28
HUT64851A (en) 1994-03-28
AU656841B2 (en) 1995-02-16
JPH069407A (ja) 1994-01-18
EP0558913B1 (en) 1999-06-23

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