ES2071706T3 - Metodo para fraccionar proteinas plasmaticas. - Google Patents

Metodo para fraccionar proteinas plasmaticas.

Info

Publication number
ES2071706T3
ES2071706T3 ES90113335T ES90113335T ES2071706T3 ES 2071706 T3 ES2071706 T3 ES 2071706T3 ES 90113335 T ES90113335 T ES 90113335T ES 90113335 T ES90113335 T ES 90113335T ES 2071706 T3 ES2071706 T3 ES 2071706T3
Authority
ES
Spain
Prior art keywords
treatment
plasma proteins
ethanol
concentration
phases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90113335T
Other languages
English (en)
Inventor
Yahiro C O The Green Cr Uemura
Kazuo C O The Green Cr Takechi
Kenji C O The Green Cro Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Application granted granted Critical
Publication of ES2071706T3 publication Critical patent/ES2071706T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

METODO DE FRACCIONAMIENTO DE PROTEINAS DE PLASMA QUE CONSISTE EN EL TRATAMIENTO DE UN MATERIAL QUE CONTENGA PROTEINAS DE PLASMA EN LA SIGUIENTE SECUENCIA DE FASES, SIEMPRE QUE LAS FASES QUE VAN DE LA (II) A LA (V) PUEDAN REALIZARSE EN UN ORDEN OPCIONAL: (I) TRATAMIENTO DE CONGELACION-DESHIELO (II) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 5 AL 10% (III) TRATAMIENTO CON UN PERMUTADOR ANIONICO (IV) CROMATOGRAFIA DE AFINIDAD CON LISINA INMOVILIZADA (V) CROMATOGRAFIA DE AFINIDAD CON HEPARINA INMOVILIZADA (VI) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 18 AL 30% (VII) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 35 AL 45%.
ES90113335T 1989-07-12 1990-07-12 Metodo para fraccionar proteinas plasmaticas. Expired - Lifetime ES2071706T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18167289 1989-07-12

Publications (1)

Publication Number Publication Date
ES2071706T3 true ES2071706T3 (es) 1995-07-01

Family

ID=16104855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90113335T Expired - Lifetime ES2071706T3 (es) 1989-07-12 1990-07-12 Metodo para fraccionar proteinas plasmaticas.

Country Status (8)

Country Link
US (1) US5138034A (es)
EP (1) EP0408029B1 (es)
JP (1) JP3018412B2 (es)
KR (1) KR910002894A (es)
CA (1) CA2019893A1 (es)
DE (1) DE69019074T2 (es)
DK (1) DK0408029T3 (es)
ES (1) ES2071706T3 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0602173B1 (en) * 1991-09-05 1999-05-26 Baxter International Inc. Topical fibrinogen complex
US5792835A (en) * 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
US5319072A (en) * 1992-01-10 1994-06-07 Alpha Therapeutic Corporation Human antithrombin-III preparation
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
DE59309332D1 (de) * 1993-12-27 1999-03-04 Rotkreuzstiftung Zentratrallab Verfahren zur Herstellung eines Konzentrates von Anti-D-Immunoglobulin G und pharmazeutische Zusammensetzung, die dieses enthält
JPH07308190A (ja) * 1994-05-18 1995-11-28 Green Cross Corp:The トロンビンの製造方法
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
JP3944267B2 (ja) * 1996-08-09 2007-07-11 財団法人化学及血清療法研究所 プロトロンビンの活性化方法および該方法に基づくトロンビンの製造方法
AUPO776897A0 (en) * 1997-07-09 1997-07-31 Csl Limited A method of achieving production gains in livestock and agents useful for same
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
CA2308610A1 (en) * 1997-11-05 1999-05-14 Welfide Corporation Heparin cofactor ii preparation and process therefor
AU770634B2 (en) * 1998-06-23 2004-02-26 Shanbrom Technologies, Llc Method and apparatus for the production of purified plasma proteins
US6194394B1 (en) * 1998-07-01 2001-02-27 Sigma-Aldrich Co. Coagulation controls for prothrombin time (PT) and activated partial thromboplastin time (APTT) assays
CA2277372C (en) * 1998-07-13 2011-03-15 Tran Quang Minh Affinity immobilised metal resins
US6274090B1 (en) * 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
DK1820516T3 (da) 1999-02-22 2013-10-28 Univ Connecticut Nye albuminfrie faktor VIII-præparater
US6472162B1 (en) * 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US6458322B1 (en) 2000-09-08 2002-10-01 Bioavailability Systems, Llc Method for simplified shipping of clinical specimens and optional direct analysis
US6957672B2 (en) * 2001-07-25 2005-10-25 Imperial Chemical Industries Plc Method for ensuring that coating compositions have correct color
JP4703922B2 (ja) * 2001-09-27 2011-06-15 日本製薬株式会社 蛋白質の精製法
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
BRPI0514435B8 (pt) 2004-08-20 2021-05-25 American Nat Red Cross isolamento sequêncial de proteínas e esquemas de purificação através de cromatografia por afinidade
JP2006160731A (ja) * 2004-11-11 2006-06-22 Kuraray Medical Inc 血液成分回収装置
US20070048387A1 (en) 2005-09-01 2007-03-01 Edwards Jeffrey D Tissue disruption treatment and composition for use thereof
US20070054031A1 (en) * 2005-09-02 2007-03-08 Keshun Liu Methods of extracting, concentrating and fractionating proteins and other chemical components
CA2647336A1 (en) 2006-04-28 2007-11-08 Cambridge Scientific Pty Ltd Cox-2 inhibitor
FR2922024B1 (fr) * 2007-10-04 2011-03-25 Stago Diagnostica Methode d'ajustement de la calibration de tests diagnostiques
MX339060B (es) 2008-11-07 2016-05-09 Baxter Int Formulaciones del factor viii.
WO2012036140A1 (ja) * 2010-09-14 2012-03-22 株式会社カネカ クリングル配列を有する蛋白質またはペプチドを精製または除去するアフィニティ担体、及びそれを用いた精製方法、除去方法
JP6370792B2 (ja) * 2012-10-03 2018-08-08 ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト タンパク質の精製方法
US9534029B2 (en) 2012-10-03 2017-01-03 Csl Behring Ag Method of purifying proteins
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
WO2016161418A1 (en) * 2015-04-02 2016-10-06 Kieu Hoang A method of manufacturing an afod intra venous injection from fraction iv
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506117D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
KR101841587B1 (ko) 2016-01-12 2018-05-14 주식회사 녹십자홀딩스 피브리노겐의 정제방법
LT3484502T (lt) * 2016-08-18 2021-12-10 Alkahest, Inc. Kraujo plazmos frakcijos, kaip su senėjimu susijusio pažinimo sutrikimo gydymo priemonė
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2710293A (en) * 1953-10-30 1955-06-07 Olin Mathieson Blood fractionation
US4025618A (en) * 1974-09-03 1977-05-24 Baxter Travenol Laboratories, Inc. Method for separation of cryoprecipitate from blook plasma

Also Published As

Publication number Publication date
CA2019893A1 (en) 1991-01-12
DE69019074D1 (de) 1995-06-08
DE69019074T2 (de) 1995-09-28
JPH03128398A (ja) 1991-05-31
KR910002894A (ko) 1991-02-26
EP0408029B1 (en) 1995-05-03
EP0408029A1 (en) 1991-01-16
JP3018412B2 (ja) 2000-03-13
US5138034A (en) 1992-08-11
DK0408029T3 (da) 1995-07-17

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