ES2071814T3 - Derivados de diazabicicloalcanos. - Google Patents

Derivados de diazabicicloalcanos.

Info

Publication number
ES2071814T3
ES2071814T3 ES90901005T ES90901005T ES2071814T3 ES 2071814 T3 ES2071814 T3 ES 2071814T3 ES 90901005 T ES90901005 T ES 90901005T ES 90901005 T ES90901005 T ES 90901005T ES 2071814 T3 ES2071814 T3 ES 2071814T3
Authority
ES
Spain
Prior art keywords
group
derivatives
diazabicicloalcanos
openally
diazobicicloalcan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90901005T
Other languages
English (en)
Inventor
Etsuo Hasegawa
Akihiro Kawaguchi
Makoto Kajitani
Mitsugi Yasumoto
Nobuo Kasahara
Junji Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2071814T3 publication Critical patent/ES2071814T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

ESTA INVENCION PROVEE DERIVADOS DIAZOBICICLOALCANO DE FORMULA (1), EN DONDE R1 REPRESENTA UN GRUPO FENILO OPCIONALMENTE SUSTITUIDO POR ALCOXILO INFERIOR, ALQUILO INFERIOR O HALOGENO, UN GRUPO TIAZOLILO, O UN GRUPO FURILO, R2 REPRESENTA OXIGENO O AZUFRE, M REPRESENTA UN NUMERO DE 3 O 4, Y N REPRESENTA UN NUMERO DE 1 O 2, LOS CUALES SON REMARCABLEMENTE EFECTIVOS EN EL TRATAMIENTO DE LA DEMENCIA SENIL, NOMINALMENTE, MEJORANDO LAS FUNCIONES CEREBRALES Y ACTIVANDO Y PROTEGIENDO EL METABOLISMO CEREBRAL.
ES90901005T 1988-12-28 1989-12-27 Derivados de diazabicicloalcanos. Expired - Lifetime ES2071814T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63335159A JP2585086B2 (ja) 1988-12-28 1988-12-28 ジアザビシクロアルカン誘導体

Publications (1)

Publication Number Publication Date
ES2071814T3 true ES2071814T3 (es) 1995-07-01

Family

ID=18285428

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90901005T Expired - Lifetime ES2071814T3 (es) 1988-12-28 1989-12-27 Derivados de diazabicicloalcanos.

Country Status (9)

Country Link
US (1) US5068235A (es)
EP (1) EP0406439B1 (es)
JP (1) JP2585086B2 (es)
KR (1) KR920008823B1 (es)
AT (1) ATE119161T1 (es)
AU (1) AU626972B2 (es)
DE (1) DE68921470T2 (es)
ES (1) ES2071814T3 (es)
WO (1) WO1990007509A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60006145T2 (de) * 1999-07-30 2004-06-09 Zenyaku Kogyo K.K. Azaindolizinon-derivate und agenzien zur verbesserung der kognitiver fähigkeiten,die dieselben als aktive inhaltstoffe enthalten
DE60203007T2 (de) * 2001-06-01 2005-07-07 Neurosearch A/S Heteroaryl-diazabicycloalkanderivaten als cns-modulatoren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives

Also Published As

Publication number Publication date
JPH02178282A (ja) 1990-07-11
KR910700252A (ko) 1991-03-14
EP0406439A4 (en) 1991-12-11
ATE119161T1 (de) 1995-03-15
DE68921470T2 (de) 1995-08-03
US5068235A (en) 1991-11-26
JP2585086B2 (ja) 1997-02-26
EP0406439B1 (en) 1995-03-01
EP0406439A1 (en) 1991-01-09
AU626972B2 (en) 1992-08-13
AU4830890A (en) 1990-08-01
WO1990007509A1 (fr) 1990-07-12
KR920008823B1 (ko) 1992-10-09
DE68921470D1 (de) 1995-04-06

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