ES2071821T3 - Metodo de analisis, composicion de reactivo y su uso para la determinacion de glucosa. - Google Patents
Metodo de analisis, composicion de reactivo y su uso para la determinacion de glucosa.Info
- Publication number
- ES2071821T3 ES2071821T3 ES90908121T ES90908121T ES2071821T3 ES 2071821 T3 ES2071821 T3 ES 2071821T3 ES 90908121 T ES90908121 T ES 90908121T ES 90908121 T ES90908121 T ES 90908121T ES 2071821 T3 ES2071821 T3 ES 2071821T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- glucose
- nicotinamide
- substances
- whole blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 3
- 239000008103 glucose Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000004458 analytical method Methods 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 abstract 2
- 230000002949 hemolytic effect Effects 0.000 abstract 2
- CXONXVMMINSQBV-NNYOXOHSSA-N (2r,3r,4s,5r)-5-[[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate Chemical compound NC(=S)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)[O-])=C1 CXONXVMMINSQBV-NNYOXOHSSA-N 0.000 abstract 1
- VEPOHXYIFQMVHW-XOZOLZJESA-N 2,3-dihydroxybutanedioic acid (2S,3S)-3,4-dimethyl-2-phenylmorpholine Chemical compound OC(C(O)C(O)=O)C(O)=O.C[C@H]1[C@@H](OCCN1C)c1ccccc1 VEPOHXYIFQMVHW-XOZOLZJESA-N 0.000 abstract 1
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 abstract 1
- MPZLSODAWKMAII-UHFFFAOYSA-N 2-chloro-8-methyl-7h-purine;pyridine-3-carboxamide Chemical compound NC(=O)C1=CC=CN=C1.ClC1=NC=C2NC(C)=NC2=N1 MPZLSODAWKMAII-UHFFFAOYSA-N 0.000 abstract 1
- HWODJSXQTMRQQL-UHFFFAOYSA-N 2-methyl-7h-purine;pyridine-3-carboxamide Chemical compound NC(=O)C1=CC=CN=C1.CC1=NC=C2NC=NC2=N1 HWODJSXQTMRQQL-UHFFFAOYSA-N 0.000 abstract 1
- VDJKJPMLWJWQIH-UHFFFAOYSA-M 5-ethylphenazin-5-ium;ethyl sulfate Chemical compound CCOS([O-])(=O)=O.C1=CC=C2[N+](CC)=C(C=CC=C3)C3=NC2=C1 VDJKJPMLWJWQIH-UHFFFAOYSA-M 0.000 abstract 1
- RXGJTUSBYWCRBK-UHFFFAOYSA-M 5-methylphenazinium methyl sulfate Chemical compound COS([O-])(=O)=O.C1=CC=C2[N+](C)=C(C=CC=C3)C3=NC2=C1 RXGJTUSBYWCRBK-UHFFFAOYSA-M 0.000 abstract 1
- CNPRPOBKEGWPEX-UHFFFAOYSA-N 7h-purine;pyridine-3-carboxamide Chemical compound C1=NC=C2NC=NC2=N1.NC(=O)C1=CC=CN=C1 CNPRPOBKEGWPEX-UHFFFAOYSA-N 0.000 abstract 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 abstract 1
- XJLXINKUBYWONI-NNYOXOHSSA-O NADP(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-NNYOXOHSSA-O 0.000 abstract 1
- PCNDJXKNXGMECE-UHFFFAOYSA-N Phenazine Natural products C1=CC=CC2=NC3=CC=CC=C3N=C21 PCNDJXKNXGMECE-UHFFFAOYSA-N 0.000 abstract 1
- 102000015439 Phospholipases Human genes 0.000 abstract 1
- 108010064785 Phospholipases Proteins 0.000 abstract 1
- 102000020006 aldose 1-epimerase Human genes 0.000 abstract 1
- 108091022872 aldose 1-epimerase Proteins 0.000 abstract 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 abstract 1
- 230000005540 biological transmission Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002824 redox indicator Substances 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
- 235000017709 saponins Nutrition 0.000 abstract 1
- 238000002798 spectrophotometry method Methods 0.000 abstract 1
- -1 thio-NADP Chemical compound 0.000 abstract 1
- 150000004043 trisaccharides Chemical class 0.000 abstract 1
- YTEJSAFVYHDCSN-UHFFFAOYSA-K zinc;benzo[a]phenoxazin-9-ylidene(dimethyl)azanium;trichloride Chemical compound [Cl-].[Cl-].[Cl-].[Zn+2].C1=CC=C2C(N=C3C=CC(C=C3O3)=[N+](C)C)=C3C=CC2=C1 YTEJSAFVYHDCSN-UHFFFAOYSA-K 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SE DESCRIBEN UN METODO, UNA COMPOSICION DE REAGENTE Y EL USO DE LOS MISMOS PARA LA DETERMINACION CUANTITATIVA DE LA GLUCOSA TOTAL EN SANGRE ENTERA SIN DILUIR. SE PONE EN CONTACTO UNA MUESTRA DE SANGRE ENTERA SIN DILUIR CON UNA COMPOSICION DE REAGENTE QUE SE ENCUENTRA EN FORMA SECA Y COMPRENDE: DEHIDROGENASA GLUCOSA (GDH); UNA O MAS SUBSTANCIAS DEL GRUPO CONSISTENTE EN DIAFORASA, FENACINE METOSULFATO, FENACINE ETOSULFATO, FENACINE FENOSULFATO Y AZUL MELDOLA; UNA O MAS SUBSTANCIAS DEL GRUPO COMPUESTO DE NAD, NADP, TIO-NAD, TIO-NADP, NICOTINAMIDA-PURINA DINUCLEOTIDE , NICOTINAMIDA-METILPURINA DINUCLEOTIDE, NICOTINAMIDA-2-CLORO-METILPURINA DINUCLEOTIDE; UNA O MAS SUBSTANCIAS DE HEMOLISIS DEL GRUPO COMPUESTO DE FOSFOLIPASA, SAPONINAS DE HEMOLISIS Y COMPUESTOS DE MONO, DIOS E HIDROCARBONOS ALIFATICOS QUE TIENEN 10-16 ATOMOS DE CARBONO; UNA TINTURA INDICADORA REDOX; Y OPCIONALMENTE MUTAROTASA. SE MIDE EL CAMBIO DE COLOR PRODUCIDO POR LA REACCION DEL REAGENTE CON GLUCOSA EN LA SANGRE ENTERA SIN DILUIR MEDIANTE ESPECTROMETRIA DE TRANSMISION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8901515A SE466158B (sv) | 1989-04-25 | 1989-04-25 | Analysmetod foer glukosbestaemning i helblod |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2071821T3 true ES2071821T3 (es) | 1995-07-01 |
Family
ID=20375802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90908121T Expired - Lifetime ES2071821T3 (es) | 1989-04-25 | 1990-04-24 | Metodo de analisis, composicion de reactivo y su uso para la determinacion de glucosa. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5278047A (es) |
| EP (1) | EP0470201B1 (es) |
| JP (1) | JPH0734757B2 (es) |
| KR (1) | KR960001139B1 (es) |
| AT (1) | ATE122102T1 (es) |
| AU (1) | AU637612B2 (es) |
| BR (1) | BR9007339A (es) |
| CA (1) | CA2053315C (es) |
| DE (1) | DE69019149T2 (es) |
| DK (1) | DK0470201T3 (es) |
| ES (1) | ES2071821T3 (es) |
| FI (1) | FI97551C (es) |
| LT (1) | LT3136B (es) |
| LV (1) | LV10122B (es) |
| NO (1) | NO300853B1 (es) |
| RU (1) | RU2050546C1 (es) |
| SE (1) | SE466158B (es) |
| WO (1) | WO1990012889A1 (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6073977A (en) * | 1994-09-08 | 2000-06-13 | Lindab Ab | Device for coupling pipe sections |
| DK9500486U3 (da) * | 1995-12-18 | 1997-04-11 | Lindab As | Indretning til sammenkobling af rørstykker |
| ES2257050T3 (es) | 1998-05-26 | 2006-07-16 | Lifecell Corporation | Conservacion por el frio de hematies humanos. |
| US6077660A (en) * | 1998-06-10 | 2000-06-20 | Abbott Laboratories | Diagnostic assay requiring a small sample of biological fluid |
| US6312888B1 (en) | 1998-06-10 | 2001-11-06 | Abbott Laboratories | Diagnostic assay for a sample of biological fluid |
| US5902731A (en) * | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| US6656697B1 (en) * | 1998-09-28 | 2003-12-02 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| LT4605B (lt) | 1999-04-07 | 2000-01-25 | Biochemijos Institutas | Fermentinis gliukozės sensorius ir jo gavimo būdas |
| RU2163722C2 (ru) * | 1999-05-12 | 2001-02-27 | Рязанский государственный медицинский университет им. акад. И.П. Павлова | Способ определения моносахаридов в сыворотке крови |
| US6485923B1 (en) | 2000-02-02 | 2002-11-26 | Lifescan, Inc. | Reagent test strip for analyte determination having hemolyzing agent |
| CA2404421A1 (en) * | 2000-03-28 | 2001-10-04 | Tianmei Ouyang | Reagent systems for detecting the presence of a reduced cofactor in a sample and methods for using the same |
| US6368818B1 (en) * | 2000-10-12 | 2002-04-09 | Qingzhong Kong | Methods and compositions for the visualization of cellular organelles using tetrazolium salts |
| US6420128B1 (en) * | 2000-09-12 | 2002-07-16 | Lifescan, Inc. | Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same |
| ATE323174T1 (de) * | 2000-09-13 | 2006-04-15 | Merck Patent Gmbh | Verfahren zur detektion und messung der biomasse |
| US7524872B2 (en) * | 2000-09-15 | 2009-04-28 | Qingzhong Kong | Method and composition for treating cancer using cellular organelle crystallizing agents |
| RU2198402C2 (ru) * | 2001-03-11 | 2003-02-10 | ГУ Тверская государственная медицинская академия | Способ диагностики сахарного диабета |
| EP1828407B1 (en) * | 2004-12-17 | 2009-02-18 | Megazyme IP Limited | Assay for determination of free d-galactose and/or l-arabinose |
| WO2006064488A1 (en) * | 2004-12-17 | 2006-06-22 | Megazyme Ip Limited | A kit for colorimetric assays of food and beverage analytes |
| US20080268485A1 (en) * | 2005-02-22 | 2008-10-30 | Guarino Julianne M | Iconic Display of Markers for a Meter |
| KR100793852B1 (ko) * | 2005-03-21 | 2008-01-11 | 김영기 | 착즙주스기 |
| KR100776914B1 (ko) | 2005-06-14 | 2007-11-15 | 주식회사 엘지화학 | 온도 측정 장치 |
| RU2394648C2 (ru) * | 2005-08-31 | 2010-07-20 | Эгомедикаль Технологиз Аг | Тест-система коагуляции |
| RU2398235C2 (ru) * | 2005-08-31 | 2010-08-27 | Эгомедикаль Технологиз Аг | Тест-система с использованием элементов неэнзиматического распознавания анализируемого вещества |
| WO2008030154A1 (en) * | 2006-09-08 | 2008-03-13 | Hemocue Ab | Haemolysing agent |
| US8008037B2 (en) | 2008-03-27 | 2011-08-30 | Roche Diagnostics Operations, Inc. | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline |
| KR101239381B1 (ko) * | 2012-05-02 | 2013-03-05 | 주식회사 아이센스 | 산화환원반응용 시약의 안정제 조성물 |
| CN103088108A (zh) * | 2012-11-16 | 2013-05-08 | 李立和 | 葡萄糖脱氢酶法检测葡萄糖的试剂盒及制备方法 |
| US9347958B2 (en) | 2014-06-27 | 2016-05-24 | Hemocue Ab | Device and method for determination of an analyte in blood |
| CN106018297A (zh) * | 2016-05-20 | 2016-10-12 | 大连大学 | 蓝莓中总黄酚含量的测定 |
| CN106018296A (zh) * | 2016-05-20 | 2016-10-12 | 大连大学 | 蓝莓中总黄酮含量的测定 |
| CN110715923A (zh) * | 2019-11-24 | 2020-01-21 | 天津市宝坻区人民医院 | α-D-葡萄糖检测试剂盒 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS164231B2 (es) * | 1972-09-28 | 1975-11-07 | ||
| DE2349819A1 (de) * | 1973-10-04 | 1975-04-17 | Eppendorf Geraetebau Netheler | Verfahren zur enzymkinetischen konzentrationsbestimmung eines substrats |
| US4120755A (en) * | 1977-04-28 | 1978-10-17 | Beckman Instruments, Inc. | Kinetic method for determination of glucose concentrations with glucose dehydrogenase |
| US4898813A (en) * | 1986-04-04 | 1990-02-06 | Albarella James P | Catalytic test composition intended to produce a range of colors |
| US4975367A (en) * | 1986-04-04 | 1990-12-04 | Miles Inc. | Catalytic test composition intended to produce a range of colors |
| US5059394A (en) * | 1986-08-13 | 1991-10-22 | Lifescan, Inc. | Analytical device for the automated determination of analytes in fluids |
-
1989
- 1989-04-25 SE SE8901515A patent/SE466158B/sv not_active IP Right Cessation
-
1990
- 1990-04-24 KR KR1019910701447A patent/KR960001139B1/ko not_active Expired - Fee Related
- 1990-04-24 AU AU55575/90A patent/AU637612B2/en not_active Ceased
- 1990-04-24 JP JP2507031A patent/JPH0734757B2/ja not_active Expired - Fee Related
- 1990-04-24 EP EP90908121A patent/EP0470201B1/en not_active Expired - Lifetime
- 1990-04-24 ES ES90908121T patent/ES2071821T3/es not_active Expired - Lifetime
- 1990-04-24 DE DE69019149T patent/DE69019149T2/de not_active Expired - Lifetime
- 1990-04-24 CA CA002053315A patent/CA2053315C/en not_active Expired - Lifetime
- 1990-04-24 BR BR909007339A patent/BR9007339A/pt not_active IP Right Cessation
- 1990-04-24 AT AT90908121T patent/ATE122102T1/de not_active IP Right Cessation
- 1990-04-24 WO PCT/SE1990/000272 patent/WO1990012889A1/en not_active Ceased
- 1990-04-24 RU SU905010235A patent/RU2050546C1/ru active
- 1990-04-24 US US07/768,249 patent/US5278047A/en not_active Expired - Lifetime
- 1990-04-24 DK DK90908121.8T patent/DK0470201T3/da active
-
1991
- 1991-10-24 NO NO914181A patent/NO300853B1/no not_active IP Right Cessation
- 1991-10-24 FI FI915020A patent/FI97551C/fi active
-
1992
- 1992-12-17 LV LVP-92-308A patent/LV10122B/en unknown
- 1992-12-30 LT LTIP275A patent/LT3136B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI97551C (fi) | 1997-01-10 |
| US5278047A (en) | 1994-01-11 |
| BR9007339A (pt) | 1992-04-28 |
| NO914181L (no) | 1991-10-24 |
| LTIP275A (en) | 1994-07-15 |
| FI915020A0 (fi) | 1991-10-24 |
| KR960001139B1 (ko) | 1996-01-19 |
| JPH04504661A (ja) | 1992-08-20 |
| DE69019149D1 (de) | 1995-06-08 |
| SE8901515L (sv) | 1990-10-26 |
| WO1990012889A1 (en) | 1990-11-01 |
| CA2053315C (en) | 2000-07-04 |
| JPH0734757B2 (ja) | 1995-04-19 |
| LV10122B (en) | 1995-02-20 |
| LV10122A (lv) | 1994-05-10 |
| KR920701476A (ko) | 1992-08-11 |
| CA2053315A1 (en) | 1990-10-26 |
| DK0470201T3 (da) | 1995-07-17 |
| ATE122102T1 (de) | 1995-05-15 |
| NO914181D0 (no) | 1991-10-24 |
| FI97551B (fi) | 1996-09-30 |
| NO300853B1 (no) | 1997-08-04 |
| AU637612B2 (en) | 1993-06-03 |
| EP0470201B1 (en) | 1995-05-03 |
| SE466158B (sv) | 1992-01-07 |
| EP0470201A1 (en) | 1992-02-12 |
| DE69019149T2 (de) | 1995-09-07 |
| LT3136B (en) | 1995-01-31 |
| SE8901515D0 (sv) | 1989-04-25 |
| RU2050546C1 (ru) | 1995-12-20 |
| AU5557590A (en) | 1990-11-16 |
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| FG2A | Definitive protection |
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