ES2074124T5 - Composicion en forma de una espuma que contiene acido 5-aminosalicilico para administracion intra-rectal. - Google Patents

Composicion en forma de una espuma que contiene acido 5-aminosalicilico para administracion intra-rectal.

Info

Publication number
ES2074124T5
ES2074124T5 ES90304314T ES90304314T ES2074124T5 ES 2074124 T5 ES2074124 T5 ES 2074124T5 ES 90304314 T ES90304314 T ES 90304314T ES 90304314 T ES90304314 T ES 90304314T ES 2074124 T5 ES2074124 T5 ES 2074124T5
Authority
ES
Spain
Prior art keywords
intra
rectal administration
aminosalicylic acid
composition
foam containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90304314T
Other languages
English (en)
Other versions
ES2074124T3 (es
Inventor
John Norman Charles Healey
Marshall Whiteman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10655759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2074124(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES2074124T3 publication Critical patent/ES2074124T3/es
Application granted granted Critical
Publication of ES2074124T5 publication Critical patent/ES2074124T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPOSICIONES FARMACEUTICAS IDEALES PARA SU ADMINISTRACION INTRARECTAL EN FORMA DE ESPUMA, QUE CONSTA DE UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE ACIDO 5-AMINOSALICILICO, UN SOPORTE ACUOSO FARMACEUTICAMENTE ACEPTABLE, Y ESPUMANTES. TAMBIEN SE DESCRIBEN LOS METODOS DE SU PREPARACION Y SU USO EN EL TRATAMIENTO DE COLITIS ULCERATIVA.
ES90304314T 1989-04-26 1990-04-23 Composicion en forma de una espuma que contiene acido 5-aminosalicilico para administracion intra-rectal. Expired - Lifetime ES2074124T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898909559A GB8909559D0 (en) 1989-04-26 1989-04-26 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ES2074124T3 ES2074124T3 (es) 1995-09-01
ES2074124T5 true ES2074124T5 (es) 2000-01-16

Family

ID=10655759

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90304314T Expired - Lifetime ES2074124T5 (es) 1989-04-26 1990-04-23 Composicion en forma de una espuma que contiene acido 5-aminosalicilico para administracion intra-rectal.

Country Status (16)

Country Link
US (1) US5082651A (es)
EP (1) EP0395329B2 (es)
JP (1) JP2566662B2 (es)
KR (1) KR0179344B1 (es)
AT (1) ATE124261T1 (es)
AU (1) AU623245B2 (es)
CA (1) CA2014889C (es)
DE (1) DE69020422T3 (es)
DK (1) DK0395329T4 (es)
ES (1) ES2074124T5 (es)
GB (1) GB8909559D0 (es)
GR (2) GR3017367T3 (es)
IE (1) IE67621B1 (es)
NZ (1) NZ233415A (es)
PT (1) PT93884B (es)
ZA (1) ZA903127B (es)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9000485D0 (sv) * 1990-02-09 1990-02-09 Pharmacia Ab Foamable composition for pharmaceutical use, use thereof and method of treatment
IT1243379B (it) * 1990-07-27 1994-06-10 Giuliani Spa Composizione farmaceutica adatta alla somministrazione rettale di principi attivi che esplicano un'azione di medicazione a livello del colon prevalentemente di tipo topico
DE69133348T3 (de) * 1990-10-22 2011-05-12 Centre for Digestive Diseases Pty, Ltd. Behandlung von nicht-entzündlichen darmerkrankungen
IT1247529B (it) * 1991-04-24 1994-12-17 Poli Ind Chimica Spa Composizioni farmaceutiche in forma di schiuma per somministrazione intravaginale, cutanea e orale
DK0586488T3 (da) * 1991-06-07 1995-09-04 Byk Nederland Bv Farmaceutisk klysterpræparat
FR2713486B1 (fr) * 1993-12-14 1996-02-09 Scophysa Nouvelles compositions pour mousses, notamment mousses rectales, et mousses ainsi obtenues.
DE4420735C2 (de) * 1994-06-15 1996-09-05 Allphamed Arzneimittel Gmbh Verfahren zur Herstellung mechanisch stabiler, sich mit hoher Auflösegeschwindigkeit auszeichnender Brausetabletten
GB9414699D0 (en) * 1994-07-21 1994-09-07 Slagel David Aqueous foamable composition
GB9503119D0 (en) * 1995-02-17 1995-04-05 Durand Ltd Medication and apparatus and method of applying medication
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6326364B1 (en) 1999-02-08 2001-12-04 Cedars-Sinai Medical Center Use of 5-aminosalicylates as antimicrobial agents
JP2001072576A (ja) * 1999-09-03 2001-03-21 Kissei Pharmaceut Co Ltd 経口用医薬品組成物
HK1048939B (zh) * 1999-09-06 2005-08-19 上田说子 化学去皮剂
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
WO2002018324A2 (en) 2000-08-29 2002-03-07 Nobex Corporation Immunoregulatory compounds, derivatives thereof and their use
CA2359812C (en) * 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
EP1312368A1 (de) * 2001-11-19 2003-05-21 Dr. Falk Pharma Gmbh Zusammensetzungen enthaltend Mesalazin zur Behandlung von entzündlichen Darmerkrankungen
IL152486A0 (en) * 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US20080317679A1 (en) * 2002-10-25 2008-12-25 Foamix Ltd. Foamable compositions and kits comprising one or more of a channel agent, a cholinergic agent, a nitric oxide donor, and related agents and their uses
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US7820145B2 (en) * 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US20050205086A1 (en) * 2002-10-25 2005-09-22 Foamix Ltd. Retinoid immunomodulating kit and composition and uses thereof
US20070292359A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
ES2532906T5 (es) 2002-10-25 2022-03-23 Foamix Pharmaceuticals Ltd Espuma cosmética y farmacéutica
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8486376B2 (en) * 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US10117812B2 (en) * 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US20070292355A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Anti-infection augmentation foamable compositions and kit and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US20060193789A1 (en) * 2002-10-25 2006-08-31 Foamix Ltd. Film forming foamable composition
US20050271596A1 (en) * 2002-10-25 2005-12-08 Foamix Ltd. Vasoactive kit and composition and uses thereof
US20080206161A1 (en) * 2002-10-25 2008-08-28 Dov Tamarkin Quiescent foamable compositions, steroids, kits and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) * 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20060233721A1 (en) * 2002-10-25 2006-10-19 Foamix Ltd. Foam containing unique oil globules
US9211259B2 (en) * 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7575739B2 (en) * 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) * 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
JP2007508243A (ja) * 2003-08-04 2007-04-05 フォーミックス エルティーディー． 両親媒性コポリマーゲル化剤を含む泡坦体
EP1663148A2 (en) * 2003-08-25 2006-06-07 Foamix Ltd. Penetrating pharmaceutical foam
US20100112088A1 (en) * 2003-08-29 2010-05-06 Jay Pravda Materials and methods for treatment of disorders associated with oxidative stress
US8916546B2 (en) 2003-08-29 2014-12-23 Therapeutic Research Llc Materials and methods for treatment and diagnosis of disorders associated with oxidative stress
US8476233B2 (en) * 2003-08-29 2013-07-02 Therapeutic Research, Llc Methods for treatment for ulcerative colitis in mammals
EP1727522A2 (en) * 2004-02-04 2006-12-06 Foamix Ltd. Cosmetic and pharmaceutical foam with solid matter
DK1773767T3 (en) 2004-07-07 2016-03-21 Biocon Ltd Synthesis of azo bound in immune regulatory relations
US20080152596A1 (en) * 2005-07-19 2008-06-26 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
JP2010502690A (ja) * 2006-09-08 2010-01-28 フォーミックス エルティーディー． 有色または着色可能発泡性組成物
EP2073794A2 (en) * 2006-11-14 2009-07-01 Foamix Ltd. Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US7645801B2 (en) 2007-01-29 2010-01-12 Alaven Pharmaceutical Llc Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US20090130029A1 (en) * 2007-11-21 2009-05-21 Foamix Ltd. Glycerol ethers vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) * 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
CA2712120A1 (en) * 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US20130202654A1 (en) 2009-11-23 2013-08-08 Cipla Limited Topical Foam Composition
RU2012126084A (ru) 2009-11-23 2013-12-27 Сипла Лимитед Пенная композиция для местного применения
US8174881B2 (en) 2009-11-24 2012-05-08 Micron Technology, Inc. Techniques for reducing disturbance in a semiconductor device
WO2014074995A1 (en) 2012-11-09 2014-05-15 Scidose, Llc Enema composition for treatment of ulcerative colitis having long term stability
JP2015168654A (ja) * 2014-03-07 2015-09-28 三笠製薬株式会社 ＮＳＡＩＤｓ含有泡沫化製剤用水性組成物
MX377365B (es) 2016-09-08 2025-03-10 Journey Medical Corp Composiciones y métodos para tratar rosácea y acné.
AU2017377017A1 (en) * 2016-12-16 2019-07-04 Ferring B.V. Rectal foam formulations

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1304682A (es) * 1969-02-03 1973-01-24
US3866800A (en) * 1969-02-12 1975-02-18 Alberto Culver Co Non-pressurized package containing self-heating products
AU1314370A (en) * 1970-02-09 1971-09-30 Alberto-Culver Company Gas-releasable and foamable compositions
US3997467A (en) * 1971-11-26 1976-12-14 Pharmacia Aktiebolag Foam forming composition
US4112942A (en) * 1974-10-09 1978-09-12 Reckitt & Colman Products Limited Method of preparing and administering a foam enema
AR205589A1 (es) * 1974-10-09 1976-05-14 Reckitt & Colmann Prod Ltd Dispositivo introductor de una composicion acuosa en una cavidad corporal
DE2755224A1 (de) * 1976-12-15 1978-07-13 Procter & Gamble Schmerzen und entzuendungen linderndes mittel zur oertlichen anwendung
US4211777A (en) * 1977-11-25 1980-07-08 Fisons Limited Compositions comprising a compound having sodium cromoglycate activity and aminosalicylic acid
WO1981002672A1 (en) * 1980-03-20 1981-10-01 Ferring Farma Lab Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease
US4440763A (en) * 1981-03-18 1984-04-03 Block Drug Company, Inc. Use of 4-aminosalicyclic acid as an anti-inflammatory agent
US4664256A (en) * 1983-09-06 1987-05-12 Farmaceutisk Laboratorium Ferring A/S Packaged stable enema solution or suspension containing 5-aminosalicyclic acid
US4657900A (en) * 1983-09-27 1987-04-14 Rowell Laboratories Pharmaceutical article of manufacture comprising a bisulfite stabilized aqueous solution of 5-aminosalicylic acid and method
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
US4752465A (en) * 1985-09-20 1988-06-21 Product Resources International, Inc. Aerosol foam
US4639367A (en) * 1985-03-18 1987-01-27 Product Resources International, Inc. Aerosol foam
US4889709A (en) * 1985-03-18 1989-12-26 Product Resources International, Inc. Aerosol foam with adsorbate and container containing same
EP0251462A3 (en) * 1986-05-28 1988-10-26 Lloyd I. Osipow Polymer-propellant compositions forming foamed structures
AU1388388A (en) * 1987-04-01 1988-10-06 Dak-Laboratoriet A/S Benzoic acid derivatives and use thereof
US4945084A (en) * 1987-07-08 1990-07-31 Norman Oksman Method and composition for topically treating anorectal or other dermal wounds

Also Published As

Publication number Publication date
GR3017367T3 (en) 1995-12-31
IE901469L (en) 1990-10-26
HK1004521A1 (en) 1998-11-27
IE67621B1 (en) 1996-04-17
AU623245B2 (en) 1992-05-07
CA2014889C (en) 2000-05-30
ES2074124T3 (es) 1995-09-01
KR900015741A (ko) 1990-11-10
KR0179344B1 (ko) 1999-03-20
DE69020422D1 (de) 1995-08-03
AU5367290A (en) 1990-11-01
ZA903127B (en) 1991-12-24
GB8909559D0 (en) 1989-06-14
GR3032575T3 (en) 2000-05-31
NZ233415A (en) 1991-05-28
EP0395329B1 (en) 1995-06-28
PT93884A (pt) 1990-11-20
ATE124261T1 (de) 1995-07-15
DK0395329T4 (da) 2000-04-10
DE69020422T3 (de) 2000-03-30
PT93884B (pt) 1996-10-31
EP0395329A3 (en) 1991-11-21
JPH02295928A (ja) 1990-12-06
DK0395329T3 (da) 1995-10-30
US5082651A (en) 1992-01-21
CA2014889A1 (en) 1990-10-26
EP0395329A2 (en) 1990-10-31
EP0395329B2 (en) 1999-11-17
JP2566662B2 (ja) 1996-12-25
DE69020422T2 (de) 1995-11-16

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