ES2075115T3 - Nuevo compuesto polipeptidico y un procedimiento para la preparacion del mismo. - Google Patents

Nuevo compuesto polipeptidico y un procedimiento para la preparacion del mismo.

Info

Publication number
ES2075115T3
ES2075115T3 ES90121558T ES90121558T ES2075115T3 ES 2075115 T3 ES2075115 T3 ES 2075115T3 ES 90121558 T ES90121558 T ES 90121558T ES 90121558 T ES90121558 T ES 90121558T ES 2075115 T3 ES2075115 T3 ES 2075115T3
Authority
ES
Spain
Prior art keywords
preparation
polypeptide compound
procedure
same
hydroxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121558T
Other languages
English (en)
Inventor
Toshiro Iwamoto
Akihiko Fujie
Kumiko Nitta
Yasuhisa Tsurumi
Nobuharu Shigematsu
Chiyoshi Kasahara
Motohiro Hino
Masakuni Okuhara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2075115T3 publication Critical patent/ES2075115T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Stringed Musical Instruments (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Materials For Medical Uses (AREA)

Abstract

UN COMPUESTO POLIPEPTIDO DE LA FORMULA GENERAL SIGUIENTE: DONDE R ELEVADO 1 ES HIDROGENO O HIDROXIDO. R (AL CUADRADO) ES HIDROGENO O HIDROXIDO. R ELEVADO 3 ES HIDROXIDO O HIDROXISULFONILOXIDO. CON LA CONDICION DE QUE CUANDO R ELEVADO 1 SEA HIDROGNEO R (AL CUADRADO) TAMBIEN LO SEA, Y UNA SAL FARMACEUTICAMENTE ACEPTABLE, PROCEDIMIENTOS PARA SU PREPARACION Y COMPUESTOS FARMACEUTICOS QUE LA COMPRENDEN. LA INVENCION CONTIENE TAMBIEN UN CULTIVO BIOLOGICAMENTE PURO DEL MICROORGANISMO COLEOFOMA SP. F-11899 (FERM BP-2635).
ES90121558T 1989-11-13 1990-11-10 Nuevo compuesto polipeptidico y un procedimiento para la preparacion del mismo. Expired - Lifetime ES2075115T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898925593A GB8925593D0 (en) 1989-11-13 1989-11-13 Fr901379 substance and preparation thereof

Publications (1)

Publication Number Publication Date
ES2075115T3 true ES2075115T3 (es) 1995-10-01

Family

ID=10666207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90121558T Expired - Lifetime ES2075115T3 (es) 1989-11-13 1990-11-10 Nuevo compuesto polipeptidico y un procedimiento para la preparacion del mismo.

Country Status (19)

Country Link
US (1) US5502033A (es)
EP (1) EP0431350B1 (es)
JP (1) JP3111470B2 (es)
KR (1) KR910009729A (es)
CN (1) CN1051757A (es)
AT (1) ATE125550T1 (es)
AU (1) AU6655790A (es)
CA (1) CA2029766A1 (es)
DE (1) DE69021176T2 (es)
DK (1) DK0431350T3 (es)
ES (1) ES2075115T3 (es)
FI (1) FI905575A7 (es)
GB (1) GB8925593D0 (es)
HU (1) HUT58820A (es)
IE (1) IE904072A1 (es)
IL (1) IL96272A0 (es)
NO (1) NO904904L (es)
PT (1) PT95876A (es)
ZA (1) ZA908892B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
IL109615A (en) * 1993-05-17 2000-12-06 Fujisawa Pharmaceutical Co Cyclic polypeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
WO1996022784A1 (en) * 1995-01-26 1996-08-01 Merck & Co., Inc. Novel antifungal cyclohexapeptides
JP3123078B2 (ja) 1996-03-08 2001-01-09 藤沢薬品工業株式会社 環状リポペプチド物質の脱アシル化法
EP0933422A4 (en) * 1996-06-13 2005-02-02 Fujisawa Pharmaceutical Co CYCLIC LIPOPEPTIDE ACYLASE
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO691897A0 (en) * 1997-05-21 1997-06-12 Fujisawa Pharmaceutical Co., Ltd. New compound
US6319757B1 (en) * 1998-07-08 2001-11-20 Caldus Semiconductor, Inc. Adhesion and/or encapsulation of silicon carbide-based semiconductor devices on ceramic substrates
WO2001092578A2 (en) * 2000-05-26 2001-12-06 Board Of Trustees Of The University Of Illinois Reagents and methods for identifying and modulating expression of genes regulated by retinoids
JP2004524318A (ja) * 2001-02-26 2004-08-12 藤沢薬品工業株式会社 エチノカンジン誘導体およびその医薬組成物および医薬としての用途
AUPS188302A0 (en) * 2002-04-22 2002-05-30 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
BRPI0820409A2 (pt) 2007-10-29 2015-05-19 Astellas Pharma Inc Composto de polipeptídeo
MX2010009953A (es) * 2008-03-14 2010-09-30 Astellas Pharma Inc Compuesto ciclico y sal del mismo.
ES2581562T3 (es) * 2010-09-29 2016-09-06 Shanghai Techwell Biopharmaceutical Co., Ltd Procedimiento para purificar compuestos lipopeptídicos cíclicos o sales de los mismos
CN102443050B (zh) * 2010-09-30 2014-06-04 上海天伟生物制药有限公司 一种环脂肽化合物或其盐的纯化方法
CN102485879A (zh) * 2010-12-03 2012-06-06 上海医药工业研究院 一种用于生产wf11899a的发酵培养基
CN102533551B (zh) * 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
CN102952179B (zh) * 2011-08-24 2015-11-25 华北制药集团新药研究开发有限责任公司 一种高纯度米卡芬净前体化合物的制备方法
CN102627689B (zh) 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102659930B (zh) 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途
CN103848900B (zh) * 2012-12-04 2015-12-02 上海医药工业研究院 一种从发酵液中分离纯化wf11899a的方法
CN114874919B (zh) * 2022-05-09 2023-06-27 中国科学院青岛生物能源与过程研究所 一株米卡芬净前体fr901379高产菌株及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322338A (en) * 1979-12-13 1982-03-30 Eli Lilly And Company Derivatives of A-30912B nucleus
US4320053A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912D nucleus
US4287120A (en) * 1979-12-13 1981-09-01 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
US4320052A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
EP0311193B1 (en) * 1987-10-07 1993-12-01 Merck & Co. Inc. Antifungal fermentation product
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ZA908892B (en) 1991-09-25
DE69021176T2 (de) 1996-01-11
CN1051757A (zh) 1991-05-29
EP0431350B1 (en) 1995-07-26
JPH03184921A (ja) 1991-08-12
IL96272A0 (en) 1991-08-16
CA2029766A1 (en) 1991-05-14
ATE125550T1 (de) 1995-08-15
HU907105D0 (en) 1991-05-28
EP0431350A1 (en) 1991-06-12
NO904904D0 (no) 1990-11-12
DE69021176D1 (de) 1995-08-31
FI905575A0 (fi) 1990-11-12
US5502033A (en) 1996-03-26
DK0431350T3 (da) 1995-09-11
GB8925593D0 (en) 1990-01-04
FI905575A7 (fi) 1991-05-14
NO904904L (no) 1991-05-14
JP3111470B2 (ja) 2000-11-20
KR910009729A (ko) 1991-06-28
IE904072A1 (en) 1991-05-22
AU6655790A (en) 1991-05-16
HUT58820A (en) 1992-03-30
PT95876A (pt) 1991-09-13

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