ES2076467T3 - Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto. - Google Patents
Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto.Info
- Publication number
- ES2076467T3 ES2076467T3 ES91303905T ES91303905T ES2076467T3 ES 2076467 T3 ES2076467 T3 ES 2076467T3 ES 91303905 T ES91303905 T ES 91303905T ES 91303905 T ES91303905 T ES 91303905T ES 2076467 T3 ES2076467 T3 ES 2076467T3
- Authority
- ES
- Spain
- Prior art keywords
- reconstruction
- skeleton
- matrix
- repaired
- sheet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 210000002805 bone matrix Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000465 moulding Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30059—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/902—Method of implanting
- Y10S623/908—Bone
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/919—Bone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
UNA MATRIZ DE HUESO ORGANICA, FLEXIBLE, ADAPTADA PARA SU USO DURANTE LA RECOMPOSICION, LA RECONSTITUCION O LA REFORMA EN VIVO DE SECCIONES PREVIAMENTE SELECCIONADAS DE UN MAMIFERO O SISTEMA ESQUELETO ANIMAL; COMPRENDIENDO UNA HOJA CONTINUA DE HUESO NATURAL, COMPLETA O PARCIALMENTE DESMINERALIZADA, DONDE EL ESPESOR DE DICHA HOJA ES TANTO COMO PARA PERMITIR MOLDEAR LA HOJA, PARA DARLE LA CONFIGURACION DESEADA EN LA ZONA A SER REPARADA, Y LA SUFICIENTE FIRMEZA Y FLEXIBILIDAD PARA PERMITIR QUE SEA MOLDEADA SIN DAÑAR LA HOJA. LA MATRIZ ES RESORVIDA POR EL CUERPO, POR ESTA CAUSA, SE ELIMINA LA NECESIDAD DE UNA OPERACION SUPLEMENTARIA PARA EXTRAER LA MATRIZ, MIENTRAS ES NECESARIO CON OTRO TIPO DE MEMBRANAS. SE HA DESCUBIERTO TAMBIEN UN METODO PARA LA RECOMPOSICION, RECONSTRUCCION O REFORMA EN VIVO DE SECCIONES PREVIAMENTE SELECCIONADAS DE UN MAMIFERO O SISTEMA ESQUELETO ANIMAL, UTILIZANDO DICHA MATRIZ.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60644990A | 1990-10-31 | 1990-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2076467T3 true ES2076467T3 (es) | 1995-11-01 |
Family
ID=24428031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91303905T Expired - Lifetime ES2076467T3 (es) | 1990-10-31 | 1991-04-30 | Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto. |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US5306304A (es) |
| EP (1) | EP0483944B1 (es) |
| DE (1) | DE69111021T2 (es) |
| ES (1) | ES2076467T3 (es) |
Families Citing this family (159)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5290558A (en) * | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
| DE69111021T2 (de) * | 1990-10-31 | 1996-01-04 | Gendler El | Flexible Membrane hergestellt aus organischer Knochenmatrix zum Ausbessern und Wiederherstellen von Knochen. |
| US5916553A (en) * | 1992-09-17 | 1999-06-29 | Schmidt; Karlheinz | Complex for inducing bone growth in the mastoid cavity |
| US5928635A (en) * | 1994-12-07 | 1999-07-27 | Schmidt; Karlheinz | Process for producing active agent complexes |
| US5830859A (en) * | 1992-09-17 | 1998-11-03 | Schmidt; Karlheinz | Complex for inducing bone growth in the maxillary sinus |
| US5507813A (en) * | 1993-12-09 | 1996-04-16 | Osteotech, Inc. | Shaped materials derived from elongate bone particles |
| US5782919A (en) | 1995-03-27 | 1998-07-21 | Sdgi Holdings, Inc. | Interbody fusion device and method for restoration of normal spinal anatomy |
| US6206922B1 (en) | 1995-03-27 | 2001-03-27 | Sdgi Holdings, Inc. | Methods and instruments for interbody fusion |
| US5711969A (en) * | 1995-04-07 | 1998-01-27 | Purdue Research Foundation | Large area submucosal tissue graft constructs |
| US5904716A (en) * | 1995-04-26 | 1999-05-18 | Gendler; El | Method for reconstituting cartilage tissue using demineralized bone and product thereof |
| US5913900A (en) * | 1995-06-07 | 1999-06-22 | Corsscart, Inc. | Substantially native meniscal cartilage heterografts |
| US5984858A (en) * | 1995-06-07 | 1999-11-16 | Crosscart, Inc. | Meniscal xenografts |
| US6231608B1 (en) | 1995-06-07 | 2001-05-15 | Crosscart, Inc. | Aldehyde and glycosidase-treated soft and bone tissue xenografts |
| US6046379A (en) * | 1995-06-07 | 2000-04-04 | Stone; Kevin R. | Meniscal xenografts |
| US5865849A (en) * | 1995-06-07 | 1999-02-02 | Crosscart, Inc. | Meniscal heterografts |
| US6110206A (en) | 1995-09-15 | 2000-08-29 | Crosscart, Inc. | Anterior cruciate ligament xenografts |
| US5944755A (en) * | 1995-09-15 | 1999-08-31 | Crosscart, Inc. | Articular cartilage xenografts |
| US5782915A (en) * | 1995-09-15 | 1998-07-21 | Stone; Kevin R. | Articular cartilage heterografts |
| US6210440B1 (en) | 1995-09-15 | 2001-04-03 | Kevin R. Stone | Anterior cruciate ligament xenografts |
| US5902338A (en) * | 1995-09-15 | 1999-05-11 | Crosscart, Inc. | Anterior cruciate ligament heterograft |
| US6049025A (en) * | 1995-09-15 | 2000-04-11 | Stone; Kevin R. | Articular cartilage xenografts |
| DE19543110C2 (de) * | 1995-11-18 | 1998-05-28 | Guy Florian Draenert | Steriles Knochenmaterial nativen Ursprungs für die Transplantation und Verfahren zur Hitzesterilisierung des Knochenmaterials |
| AU1535097A (en) * | 1996-01-17 | 1997-08-11 | Osteotech, Inc. | Process and apparatus for producing flexible sheets from demineralized, elongate, bone particles |
| US5868749A (en) * | 1996-04-05 | 1999-02-09 | Reed; Thomas M. | Fixation devices |
| US5755791A (en) * | 1996-04-05 | 1998-05-26 | Purdue Research Foundation | Perforated submucosal tissue graft constructs |
| US5919234A (en) | 1996-08-19 | 1999-07-06 | Macropore, Inc. | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
| US5676146B1 (en) * | 1996-09-13 | 2000-04-18 | Osteotech Inc | Surgical implant containing a resorbable radiopaque marker and method of locating such within a body |
| EP0896825B1 (en) | 1997-08-14 | 2002-07-17 | Sulzer Innotec Ag | Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors |
| US6090998A (en) * | 1997-10-27 | 2000-07-18 | University Of Florida | Segmentally demineralized bone implant |
| US6652592B1 (en) | 1997-10-27 | 2003-11-25 | Regeneration Technologies, Inc. | Segmentally demineralized bone implant |
| US5899939A (en) | 1998-01-21 | 1999-05-04 | Osteotech, Inc. | Bone-derived implant for load-supporting applications |
| US6712851B1 (en) * | 1998-01-23 | 2004-03-30 | Macropore Biosurgery, Inc. | Resorbable, macro-porous non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
| US6986788B2 (en) * | 1998-01-30 | 2006-01-17 | Synthes (U.S.A.) | Intervertebral allograft spacer |
| US6290718B1 (en) * | 1998-02-02 | 2001-09-18 | Regeneration Technologies, Inc. | Luminal graft, stent or conduit made of cortical bone |
| US6123731A (en) | 1998-02-06 | 2000-09-26 | Osteotech, Inc. | Osteoimplant and method for its manufacture |
| US6998135B1 (en) | 1998-02-27 | 2006-02-14 | Musculoskeletal Transplant Foundation | Demineralized corticocancellous bone sheet |
| US6383732B1 (en) | 1999-02-11 | 2002-05-07 | Crosscart, Inc. | Method of preparing xenograft heart valves |
| US6972041B1 (en) | 1998-03-16 | 2005-12-06 | Crosscart, Inc. | Bone xenografts |
| JP2002510530A (ja) | 1998-04-07 | 2002-04-09 | マクロポア インコーポレイテッド | 組織案内表面波形部付きのメンブレン |
| US6258778B1 (en) | 1998-07-13 | 2001-07-10 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
| US6916783B2 (en) * | 1998-07-13 | 2005-07-12 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
| DK1100417T3 (da) | 1998-08-03 | 2004-08-02 | Synthes Ag | Intervertebralt allograftafstandsstykke |
| US6206923B1 (en) | 1999-01-08 | 2001-03-27 | Sdgi Holdings, Inc. | Flexible implant using partially demineralized bone |
| US6267786B1 (en) | 1999-02-11 | 2001-07-31 | Crosscart, Inc. | Proteoglycan-reduced soft tissue xenografts |
| US6113638A (en) * | 1999-02-26 | 2000-09-05 | Williams; Lytton A. | Method and apparatus for intervertebral implant anchorage |
| AU6406700A (en) * | 1999-03-16 | 2000-10-04 | Regeneration Technologies, Inc. | Molded implants for orthopedic applications |
| US6340369B1 (en) * | 1999-08-13 | 2002-01-22 | Bret A. Ferree | Treating degenerative disc disease with harvested disc cells and analogues of the extracellular matrix |
| US20070038231A1 (en) | 1999-05-28 | 2007-02-15 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
| US6969404B2 (en) * | 1999-10-08 | 2005-11-29 | Ferree Bret A | Annulus fibrosis augmentation methods and apparatus |
| US20060247665A1 (en) | 1999-05-28 | 2006-11-02 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
| US7273497B2 (en) | 1999-05-28 | 2007-09-25 | Anova Corp. | Methods for treating a defect in the annulus fibrosis |
| US7371408B1 (en) | 1999-06-07 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
| US6793677B2 (en) * | 1999-08-13 | 2004-09-21 | Bret A. Ferree | Method of providing cells and other biologic materials for transplantation |
| US6755863B2 (en) * | 1999-10-08 | 2004-06-29 | Bret A. Ferree | Rotator cuff repair using engineered tissues |
| US7435260B2 (en) | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
| US6454804B1 (en) * | 1999-10-08 | 2002-09-24 | Bret A. Ferree | Engineered tissue annulus fibrosis augmentation methods and apparatus |
| US6685695B2 (en) * | 1999-08-13 | 2004-02-03 | Bret A. Ferree | Method and apparatus for providing nutrition to intervertebral disc tissue |
| US6645247B2 (en) * | 1999-10-08 | 2003-11-11 | Bret A. Ferree | Supplementing engineered annulus tissues with autograft of allograft tendons |
| US20030026788A1 (en) * | 1999-10-08 | 2003-02-06 | Ferree Bret A. | Use of extracellular matrix tissue to preserve cultured cell phenotype |
| US6648920B2 (en) * | 1999-10-08 | 2003-11-18 | Bret A. Ferree | Natural and synthetic supplements to engineered annulus and disc tissues |
| US6648919B2 (en) * | 1999-10-14 | 2003-11-18 | Bret A. Ferree | Transplantation of engineered meniscus tissue to the intervertebral disc |
| US20030228288A1 (en) | 1999-10-15 | 2003-12-11 | Scarborough Nelson L. | Volume maintaining osteoinductive/osteoconductive compositions |
| US6379385B1 (en) | 2000-01-06 | 2002-04-30 | Tutogen Medical Gmbh | Implant of bone matter |
| US6716247B2 (en) | 2000-02-04 | 2004-04-06 | Gary K. Michelson | Expandable push-in interbody spinal fusion implant |
| EP1645248B8 (en) * | 2000-02-04 | 2010-06-16 | Warsaw Orthopedic, Inc. | Expandable interbody spinal fusion implant having pivotally attached blocker |
| US6814756B1 (en) | 2000-02-04 | 2004-11-09 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion |
| US6709458B2 (en) * | 2000-02-04 | 2004-03-23 | Gary Karlin Michelson | Expandable push-in arcuate interbody spinal fusion implant with tapered configuration during insertion |
| US6500205B1 (en) * | 2000-04-19 | 2002-12-31 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion |
| CA2399224A1 (en) * | 2000-02-18 | 2001-08-23 | Regeneration Technologies, Inc. | Implantable tissues infused with growth factors and other additives |
| US6723335B1 (en) | 2000-04-07 | 2004-04-20 | Jeffrey William Moehlenbruck | Methods and compositions for treating intervertebral disc degeneration |
| DE10026306A1 (de) * | 2000-05-26 | 2001-11-29 | Tutogen Medical Gmbh | Transplantat |
| JP2004501719A (ja) * | 2000-07-03 | 2004-01-22 | オステオテック インコーポレーテッド | 骨から誘導された骨形成性インプラント |
| US6332779B1 (en) | 2000-07-03 | 2001-12-25 | Osteotech, Inc. | Method of hard tissue repair |
| US6863694B1 (en) | 2000-07-03 | 2005-03-08 | Osteotech, Inc. | Osteogenic implants derived from bone |
| US6808537B2 (en) * | 2000-07-07 | 2004-10-26 | Gary Karlin Michelson | Expandable implant with interlocking walls |
| US9387094B2 (en) | 2000-07-19 | 2016-07-12 | Warsaw Orthopedic, Inc. | Osteoimplant and method of making same |
| US6432436B1 (en) * | 2000-10-03 | 2002-08-13 | Musculoskeletal Transplant Foundation | Partially demineralized cortical bone constructs |
| US6576249B1 (en) | 2000-11-13 | 2003-06-10 | El Gendler | Bone putty and method |
| US6579319B2 (en) | 2000-11-29 | 2003-06-17 | Medicinelodge, Inc. | Facet joint replacement |
| US20050080486A1 (en) | 2000-11-29 | 2005-04-14 | Fallin T. Wade | Facet joint replacement |
| US6419703B1 (en) | 2001-03-01 | 2002-07-16 | T. Wade Fallin | Prosthesis for the replacement of a posterior element of a vertebra |
| US6565605B2 (en) | 2000-12-13 | 2003-05-20 | Medicinelodge, Inc. | Multiple facet joint replacement |
| US7323193B2 (en) | 2001-12-14 | 2008-01-29 | Osteotech, Inc. | Method of making demineralized bone particles |
| US7118579B2 (en) | 2001-02-04 | 2006-10-10 | Sdgi Holdings, Inc. | Instrumentation for inserting an expandable interbody spinal fusion implant |
| US6652593B2 (en) | 2001-02-28 | 2003-11-25 | Synthes (Usa) | Demineralized bone implants |
| US7090698B2 (en) | 2001-03-02 | 2006-08-15 | Facet Solutions | Method and apparatus for spine joint replacement |
| WO2002083188A2 (en) * | 2001-04-16 | 2002-10-24 | Cassidy James J | Dense/porous structures for use as bone substitutes |
| US7371409B2 (en) | 2001-09-06 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
| US7163691B2 (en) | 2001-10-12 | 2007-01-16 | Osteotech, Inc. | Bone graft |
| EP1456278B1 (en) * | 2001-12-21 | 2006-03-08 | IsoTis Orthobiologics, Inc. | Compositions containing end-capped polyalkylene glycols |
| US7232802B2 (en) | 2001-12-21 | 2007-06-19 | Zimmer Orthobiologics, Inc. | Compositions and methods for promoting myocardial and peripheral angiogenesis |
| US7205337B2 (en) * | 2001-12-21 | 2007-04-17 | Isotis Orthobiologics, Inc. | End-capped polymers and compositions containing such compounds |
| US7833255B2 (en) | 2001-12-27 | 2010-11-16 | Osteotech, Inc. | Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners |
| GB2383954A (en) * | 2002-01-14 | 2003-07-16 | Crawford Francis Gray | Sinus prop |
| US7708776B1 (en) | 2002-01-16 | 2010-05-04 | Nuvasive, Inc. | Intervertebral disk replacement system and methods |
| AR038680A1 (es) * | 2002-02-19 | 2005-01-26 | Synthes Ag | Implante intervertebral |
| CA2480839C (en) * | 2002-03-29 | 2011-01-04 | Wright Medical Technology, Inc. | Bone graft substitute composition |
| DE60334897D1 (de) * | 2002-03-30 | 2010-12-23 | Infinity Orthopaedics Co Ltd | Medizinische Intervertebrale Vorrichtung |
| US20060204544A1 (en) * | 2002-05-20 | 2006-09-14 | Musculoskeletal Transplant Foundation | Allograft bone composition having a gelatin binder |
| US7299805B2 (en) | 2002-06-07 | 2007-11-27 | Marctec, Llc | Scaffold and method for implanting cells |
| US6652887B1 (en) | 2002-06-24 | 2003-11-25 | Wright Medical Technology, Inc. | Bone graft substitute composition |
| US7291179B2 (en) * | 2002-06-24 | 2007-11-06 | Wright Medical Technology, Inc. | Bone graft substitute composition |
| US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
| US7507257B2 (en) * | 2003-02-04 | 2009-03-24 | Wright Medical Technology, Inc. | Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects |
| DE50313446D1 (de) | 2003-02-06 | 2011-03-10 | Synthes Gmbh | Zwischenwirbelimplantat |
| US7819903B2 (en) | 2003-03-31 | 2010-10-26 | Depuy Spine, Inc. | Spinal fixation plate |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7252685B2 (en) * | 2003-06-05 | 2007-08-07 | Sdgi Holdings, Inc. | Fusion implant and method of making same |
| WO2004110308A2 (en) | 2003-06-11 | 2004-12-23 | Osteotech, Inc. | Osteoimplants and methods for their manufacture |
| US7226482B2 (en) * | 2003-09-02 | 2007-06-05 | Synthes (U.S.A.) | Multipiece allograft implant |
| US20050074476A1 (en) * | 2003-10-03 | 2005-04-07 | El Gendler | Cartilidge and bone induction by artificially perforated organic bone matrix augmented by undifferentiated cells suspended in bone gel |
| US8926700B2 (en) | 2003-12-10 | 2015-01-06 | Gmedelware 2 LLC | Spinal facet joint implant |
| US8353933B2 (en) | 2007-04-17 | 2013-01-15 | Gmedelaware 2 Llc | Facet joint replacement |
| US8562649B2 (en) | 2004-02-17 | 2013-10-22 | Gmedelaware 2 Llc | System and method for multiple level facet joint arthroplasty and fusion |
| US7993373B2 (en) | 2005-02-22 | 2011-08-09 | Hoy Robert W | Polyaxial orthopedic fastening apparatus |
| US8764801B2 (en) | 2005-03-28 | 2014-07-01 | Gmedelaware 2 Llc | Facet joint implant crosslinking apparatus and method |
| US7507242B2 (en) | 2004-06-02 | 2009-03-24 | Facet Solutions | Surgical measurement and resection framework |
| DE102004036882A1 (de) * | 2004-07-22 | 2006-02-16 | Ossacur Ag | Bioresorbierbares Material zur Füllung von Knochendefekten |
| DE102004036881A1 (de) * | 2004-07-22 | 2006-02-16 | Ossacur Ag | Bioresorbierbares Material zur Füllung von Knochendefekten |
| EP1794055A1 (en) * | 2004-09-07 | 2007-06-13 | Smith and Nephew, Inc. | Methods and devices for sterile field transfer |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US7250550B2 (en) * | 2004-10-22 | 2007-07-31 | Wright Medical Technology, Inc. | Synthetic bone substitute material |
| EP1833452A1 (en) | 2004-11-23 | 2007-09-19 | Smith and Nephew, Inc. | Composite mixer |
| US7722647B1 (en) | 2005-03-14 | 2010-05-25 | Facet Solutions, Inc. | Apparatus and method for posterior vertebral stabilization |
| DE202005009755U1 (de) * | 2005-06-21 | 2005-09-08 | Cervitech, Inc. | Halter für Zwischenwirbelprothesen |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| US8025903B2 (en) | 2005-09-09 | 2011-09-27 | Wright Medical Technology, Inc. | Composite bone graft substitute cement and articles produced therefrom |
| CN103349793B (zh) | 2005-09-09 | 2016-02-10 | 阿格诺沃斯健康关爱公司 | 复合骨移植替代物水泥以及由其制得的制品 |
| JP2009508596A (ja) | 2005-09-19 | 2009-03-05 | ヒストジェニックス コーポレイション | 細胞支持基材及びその調製方法 |
| US8435295B2 (en) | 2005-09-26 | 2013-05-07 | Infinity Orthopaedics Company | System and method for intervertebral implant delivery and removal |
| US9132208B2 (en) * | 2008-08-07 | 2015-09-15 | Lifenet Health | Composition for a tissue repair implant and methods of making the same |
| US9005646B2 (en) | 2005-10-12 | 2015-04-14 | Lifenet Health | Compositions for repair of defects in tissues, and methods of making the same |
| WO2007056671A1 (en) | 2005-11-02 | 2007-05-18 | Osteotech, Inc. | Hemostatic bone graft |
| US20100305704A1 (en) | 2006-02-27 | 2010-12-02 | Synthes Gmbh | Intervertebral implant with fixation geometry |
| US8043377B2 (en) * | 2006-09-02 | 2011-10-25 | Osprey Biomedical, Inc. | Implantable intervertebral fusion device |
| US7837707B2 (en) * | 2006-12-31 | 2010-11-23 | Yamada Jason M | Internal procedure for closing sinus membrane perforations |
| WO2008086467A2 (en) | 2007-01-10 | 2008-07-17 | Facet Solutions, Inc. | Taper-locking fixation system |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| US20090012620A1 (en) * | 2007-07-06 | 2009-01-08 | Jim Youssef | Implantable Cervical Fusion Device |
| KR20100105580A (ko) | 2007-11-16 | 2010-09-29 | 신세스 게엠바하 | 낮은 프로파일 추간 임플란트 |
| US20090181807A1 (en) * | 2008-01-16 | 2009-07-16 | Jason Miguel De Los Santos | Golfing aid |
| WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| JP5554002B2 (ja) * | 2008-03-10 | 2014-07-23 | 株式会社ジーシー | 軟骨組織再生シートの作製方法 |
| US20090259263A1 (en) * | 2008-04-11 | 2009-10-15 | Biomet Microfixation, Inc. | Apparatus and methods of fixating bone |
| JP2012506733A (ja) | 2008-10-24 | 2012-03-22 | ウォーソー・オーソペディック・インコーポレーテッド | 骨形成を促進するための組成物および方法 |
| BRPI0921485A2 (pt) | 2008-11-07 | 2016-01-12 | Synthes Gmbh | montagem de placa acoplada e espaçador de intercorpo vertebral |
| US9192695B2 (en) * | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| US9241809B2 (en) | 2010-12-21 | 2016-01-26 | DePuy Synthes Products, Inc. | Intervertebral implants, systems, and methods of use |
| US9220604B2 (en) | 2010-12-21 | 2015-12-29 | DePuy Synthes Products, Inc. | Intervertebral implants, systems, and methods of use |
| ES2387057B1 (es) | 2011-02-16 | 2013-07-19 | Valeria Lucila Sainz Prestel | Uso de un extracto vegetal como principio activo para la elaboración de un producto con actividad farmacológica para el tratamiento de lesiones tisulares y procedimiento de obtención del extracto |
| US9585764B2 (en) * | 2012-07-26 | 2017-03-07 | Warsaw Orthopedic, Inc. | Bone implant device |
| CA2899713C (en) | 2013-03-15 | 2022-07-19 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
| US8888823B1 (en) | 2014-02-05 | 2014-11-18 | Theodore Malinin | Thin bendable bone plate for bone deficit repair and method of preparation |
| US9867718B2 (en) | 2014-10-22 | 2018-01-16 | DePuy Synthes Products, Inc. | Intervertebral implants, systems, and methods of use |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| US10549011B2 (en) | 2015-10-26 | 2020-02-04 | Osteolife Biomedical, Llc | Bone putty and gel systems and methods |
| US20170128633A1 (en) | 2015-11-10 | 2017-05-11 | Theodore Malinin | Bioactive Implants and Methods of Making and Using |
| US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416175B (sv) * | 1979-03-07 | 1980-12-08 | Per Ingvar Branemark | For implantering i kroppsvevnad serskilt benvevnad, avsett material |
| US4430760A (en) * | 1981-12-18 | 1984-02-14 | Collagen Corporation | Nonstress-bearing implantable bone prosthesis |
| US4394370A (en) * | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
| US4472840A (en) * | 1981-09-21 | 1984-09-25 | Jefferies Steven R | Method of inducing osseous formation by implanting bone graft material |
| US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
| US4485097A (en) * | 1982-05-26 | 1984-11-27 | Massachusetts Institute Of Technology | Bone-equivalent and method for preparation thereof |
| US4932973A (en) * | 1983-09-30 | 1990-06-12 | El Gendler | Cartilage and bone induction by artificially perforated organic bone matrix |
| US5053049A (en) * | 1985-05-29 | 1991-10-01 | Baxter International | Flexible prostheses of predetermined shapes and process for making same |
| US4627853A (en) * | 1985-05-29 | 1986-12-09 | American Hospital Supply Corporation | Method of producing prostheses for replacement of articular cartilage and prostheses so produced |
| US4678470A (en) * | 1985-05-29 | 1987-07-07 | American Hospital Supply Corporation | Bone-grafting material |
| GB8819755D0 (en) * | 1988-08-19 | 1988-09-21 | Geistlich Soehne Ag | Chemical compound |
| DE69111021T2 (de) * | 1990-10-31 | 1996-01-04 | Gendler El | Flexible Membrane hergestellt aus organischer Knochenmatrix zum Ausbessern und Wiederherstellen von Knochen. |
-
1991
- 1991-04-30 DE DE69111021T patent/DE69111021T2/de not_active Expired - Fee Related
- 1991-04-30 EP EP91303905A patent/EP0483944B1/en not_active Expired - Lifetime
- 1991-04-30 ES ES91303905T patent/ES2076467T3/es not_active Expired - Lifetime
-
1993
- 1993-01-13 US US08/004,093 patent/US5306304A/en not_active Expired - Lifetime
- 1993-11-12 US US08/150,845 patent/US5464439A/en not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/468,963 patent/US5556430A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69111021D1 (de) | 1995-08-10 |
| EP0483944B1 (en) | 1995-07-05 |
| US5556430A (en) | 1996-09-17 |
| US5306304A (en) | 1994-04-26 |
| EP0483944A1 (en) | 1992-05-06 |
| DE69111021T2 (de) | 1996-01-04 |
| US5464439A (en) | 1995-11-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2076467T3 (es) | Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto. | |
| ES2111566T3 (es) | Equivalentes compuestos de piel viva. | |
| ES2077034T3 (es) | Metodo de cultivo de tejidos para la transformacion de celulas vegetales. | |
| DK1019493T3 (da) | Fremstilling af hæmatopoietiske celler fra multipotente neurale stamceller | |
| AR017677A1 (es) | Metodo de seleccion de semillas danadas de las semillas no danadas | |
| DE50004406D1 (de) | In vitro-Verfahren zum Herstellen einer homologen Herzklappen- oder Gefässprothese | |
| PT871414E (pt) | Metodos para a preparacao de tecido para implantacao | |
| ES2061720T3 (es) | Transformacion de tejido vegetal. | |
| JP2010505857A5 (es) | ||
| MX2019009549A (es) | Metodo de injerto de celulas a partir de tejidos solidos. | |
| ES2145791T3 (es) | Replica de implante dental. | |
| BR8202494A (pt) | Processo para preparar tecido natural fixo bem como tecido natural fixo valvula cardiaca fixa de suino e tecido fixo de pericardio de bovino adequados para implante | |
| NL178227C (nl) | Werkwijze ter bereiding van een adsorbens ten gebruike in kunstmatige organen. | |
| NO890260L (no) | Fremgangsmaate ved fremstilling av cytostatin c eller modifikasjoner derav og dna-sekvens for anvendelse ved utfoerelse av fremgangsmaaten. | |
| CO4790178A1 (es) | Metodo para generar cultivos de celulas embriogenicas para la produccion de bananas transgenicas | |
| UY23859A1 (es) | Metodo para reproducir coniferas mediante embriogenesis somatica utilizando un medio de mantenimiento enriquecido en maltosa | |
| DE50100859D1 (de) | Hautmatrix zur Abdeckung und Regenerierung verletzter Hautpartien sowie Verfahren zu ihrer Herstellung | |
| ES2482765T3 (es) | Células madre de Müller | |
| Płytycz et al. | Preliminary studies on the growth and movements of the yellow-bellied toad, Bombina variegata (Anura: Discoglossidae) | |
| SE9201021D0 (sv) | Odlingskaerl med organ foer automatisk hantering | |
| ES2116846B1 (es) | Sistema de enganche y desenganche rapido para flotadores y plomos torpedo en sedales de pesca. | |
| Kuhn et al. | A modified polyester embedding medium for sectioning | |
| WANG et al. | Research progress in tissue-engineered tracheal vascularization | |
| Randall | Problems in skin grafting | |
| AR025520A1 (es) | Procedimiento de fabricacion de un implante dental, dispositivo de cultivo de celulas e implante dental |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 483944 Country of ref document: ES |