ES2077034T3 - Metodo de cultivo de tejidos para la transformacion de celulas vegetales. - Google Patents

Metodo de cultivo de tejidos para la transformacion de celulas vegetales.

Info

Publication number
ES2077034T3
ES2077034T3 ES90311229T ES90311229T ES2077034T3 ES 2077034 T3 ES2077034 T3 ES 2077034T3 ES 90311229 T ES90311229 T ES 90311229T ES 90311229 T ES90311229 T ES 90311229T ES 2077034 T3 ES2077034 T3 ES 2077034T3
Authority
ES
Spain
Prior art keywords
cells
transformation
cultivation method
vegetable cells
tissue cultivation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90311229T
Other languages
English (en)
Inventor
Dwight Tomes
Dennis Bidney
Charisse Marie Buising
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pioneer Hi Bred International Inc
Original Assignee
Pioneer Hi Bred International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred International Inc filed Critical Pioneer Hi Bred International Inc
Application granted granted Critical
Publication of ES2077034T3 publication Critical patent/ES2077034T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8206—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated
    • C12N15/8207—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

UN METODO PARA TRANSFORMAR MAS EFICIENTEMENTE CELULAS DE PLANTAS EN CULTIVO DE TEJIDOS, EL CUAL INCLUYE TRATAMIENTO CON UNA CITOQUININA SEGUIDO POR INCUBACION DURANTE UN PERIODO SUFICIENTE PARA PERMITIR A LAS CELULAS NO DIFERENCIADAS DEL TEJIDO DEL NODO COTILEDONEO DIFERENCIARSE EN CELULAS MERISTEMICAS Y PARA PERMITIR QUE LAS CELULAS ENTREN EN LA FASE DE DESARROLLO ENTRE LA FASE G1 Y LA DE DIVISION.
ES90311229T 1989-10-17 1990-10-12 Metodo de cultivo de tejidos para la transformacion de celulas vegetales. Expired - Lifetime ES2077034T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/422,875 US5322783A (en) 1989-10-17 1989-10-17 Soybean transformation by microparticle bombardment

Publications (1)

Publication Number Publication Date
ES2077034T3 true ES2077034T3 (es) 1995-11-16

Family

ID=23676780

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90311229T Expired - Lifetime ES2077034T3 (es) 1989-10-17 1990-10-12 Metodo de cultivo de tejidos para la transformacion de celulas vegetales.

Country Status (7)

Country Link
US (1) US5322783A (es)
EP (1) EP0424047B1 (es)
AT (1) ATE124995T1 (es)
DE (1) DE69020850T2 (es)
DK (1) DK0424047T3 (es)
ES (1) ES2077034T3 (es)
GR (1) GR3017310T3 (es)

Families Citing this family (605)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803499B1 (en) 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) * 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
WO1991010725A1 (en) 1990-01-22 1991-07-25 Dekalb Plant Genetics Fertile transgenic corn plants
US6777589B1 (en) 1990-01-22 2004-08-17 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5484956A (en) * 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
US6605712B1 (en) * 1990-12-20 2003-08-12 Arch Development Corporation Gene transcription and ionizing radiation: methods and compositions
ATE207126T1 (de) * 1991-05-15 2001-11-15 Monsanto Technology Llc Verfahren zur schöpfung einer transformierten reispflanze
US5324646A (en) * 1992-01-06 1994-06-28 Pioneer Hi-Bred International, Inc. Methods of regeneration of Medicago sativa and expressing foreign DNA in same
AU4469793A (en) * 1992-08-19 1994-02-24 Monsanto Company Method for transforming monocotyledonous plants
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
US5780709A (en) * 1993-08-25 1998-07-14 Dekalb Genetics Corporation Transgenic maize with increased mannitol content
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
FR2709496B1 (fr) * 1993-08-30 1995-11-03 Limagrain Holding Groupe Procédé de production de plantes transgéniques, entièrement transformées en génération T0, à partir de méristèmes.
EP0757102A1 (en) * 1995-08-04 1997-02-05 Plant Genetic Systems N.V. Genetic transformation using a PARP inhibitor
EP0861589A1 (en) * 1997-02-21 1998-09-02 K.U. Leuven Research & Development Method of generating embryogenic cell cultures for the production of bananas (musa spp.)
US5948956A (en) * 1997-10-16 1999-09-07 Oms Investments, Inc. Transgenic plants and method for node segment transformation
US20060260005A1 (en) * 1998-02-26 2006-11-16 Zhizhen Chen Transformation of Brassica
US20040045056A1 (en) * 1998-02-26 2004-03-04 Zhizheng Chen Transformation of Brassica
US6586658B1 (en) 1998-03-06 2003-07-01 Metabolix, Inc. Modification of fatty acid metabolism in plants
ATE317014T1 (de) * 1998-07-30 2006-02-15 Metabolix Inc Bifunktionelle enzyme zur biopolymerherstellung
US7897843B2 (en) 1999-03-23 2011-03-01 Mendel Biotechnology, Inc. Transcriptional regulation of plant biomass and abiotic stress tolerance
US6429357B1 (en) 1999-05-14 2002-08-06 Dekalb Genetics Corp. Rice actin 2 promoter and intron and methods for use thereof
AU6677400A (en) 1999-08-20 2001-03-19 University Of Guelph Improved method for the transformation and regeneration of plants
CA2394367C (en) * 1999-12-15 2014-01-21 Regents Of The University Of Minnesota Method to enhance agrobacterium-mediated transformation of plants
EE200200443A (et) 2000-02-09 2003-12-15 Basf Aktiengesellschaft Uus elongaasigeen ning polüküllastumata rasvhapete saamise meetod
GB0002814D0 (en) 2000-02-09 2000-03-29 Univ York Nucleic acids and their uses
AU2001236839A1 (en) 2000-02-11 2001-08-20 Metabolix, Inc. Multi-gene expression constructs containing modified inteins
US6750379B2 (en) 2000-03-09 2004-06-15 Dekalb Genetics Corporation Homologous recombination-mediated transgene alterations in plants
US6580019B1 (en) 2000-03-09 2003-06-17 Dekalb Genetics Corporation Non-reciprocal recombination-mediated transgene deletion in transgenic plants
EP1373530B1 (en) 2000-04-07 2006-12-13 BASF Plant Science GmbH Protein kinase stress-related protein and methods of use in plants
US6875907B2 (en) 2000-09-13 2005-04-05 Pioneer Hi-Bred International, Inc. Antimicrobial peptides and methods of use
WO2005012515A2 (en) 2003-04-29 2005-02-10 Pioneer Hi-Bred International, Inc. Novel glyphosate-n-acetyltransferase (gat) genes
US20020129455A1 (en) * 2000-12-19 2002-09-19 Yung-Feng Wei Structure for CD/VCD cleaner
CA2441265A1 (en) 2001-03-16 2002-09-26 Basf Plant Science Gmbh Sugar and lipid metabolism regulators in plants
US20040242523A1 (en) * 2003-03-06 2004-12-02 Ana-Farber Cancer Institue And The Univiersity Of Chicago Chemo-inducible cancer gene therapy
EP1390075B1 (en) * 2001-04-06 2012-01-18 The University of Chicago Chemotherapeutic induction of egr-1 promoter activity in gene therapy
US8034791B2 (en) 2001-04-06 2011-10-11 The University Of Chicago Activation of Egr-1 promoter by DNA damaging chemotherapeutics
WO2002095002A2 (en) 2001-05-22 2002-11-28 University Of Chicago N4 virion single-stranded dna dependent rna polymerase
WO2002099076A2 (en) 2001-06-04 2002-12-12 Basf Plant Science Gmbh Sugar and lipid metabolism regulators in plants ii
WO2003000863A2 (en) 2001-06-22 2003-01-03 Pioneer Hi-Bred International, Inc. Defensin polynucleotides and methods of use
AU2002319037B2 (en) 2001-08-09 2008-05-29 University Of Saskatchewan Wheat plants having increased resistance to imidazolinone herbicides
DE60231717D1 (de) 2001-08-10 2009-05-07 Basf Plant Science Gmbh Zucker- und lipidmetabolismusregulatoren bei pflanzen iii
EP1423508B1 (en) 2001-09-05 2012-01-18 BASF Plant Science GmbH Protein phosphatase stress-related polypeptides and methods of use in plants
US20030046733A1 (en) * 2001-09-06 2003-03-06 Dias Kalyani Mallika Transformation of soybeans
AR037038A1 (es) 2001-10-26 2004-10-20 Baylor College Medicine Una composicion y metodo para alterar la masa corporal magra y las propiedades oseas en un sujeto
EP1451326B1 (en) 2001-11-09 2009-11-11 BASF Plant Science GmbH Protein kinase stress-related polypeptides and methods of use in plants
ES2365912T3 (es) 2001-11-09 2011-10-13 Basf Plant Science Gmbh Polipéptidos del factor de transcripción relacionados con el estrés y métodos de uso en plantas.
AU2002357143B2 (en) 2001-12-11 2009-07-30 Advisys, Inc. Growth hormone releasing hormone supplementation for treating chronically ill subjects
EP1572902B1 (en) 2002-02-01 2014-06-11 Life Technologies Corporation HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES
ATE556714T1 (de) 2002-02-01 2012-05-15 Life Technologies Corp Doppelsträngige oligonukleotide
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
US6948972B2 (en) * 2002-03-27 2005-09-27 Pent Technologies, Inc. Overhead lighting splitter
AU2003209289A1 (en) 2002-05-01 2003-11-17 The University Of Georgia Research Foundation, Inc. Transposable elements in rice and methods of use
US7579517B2 (en) 2002-05-08 2009-08-25 Basf Plant Science Gmbh Methods for increasing oil content in plants
WO2003099216A2 (en) 2002-05-22 2003-12-04 Monsanto Technology Llc Fatty acid desaturases from fungi
EP1551218B1 (en) 2002-07-10 2017-05-17 The Department of Agriculture, Western Australia Wheat plants having increased resistance to imidazolinone herbicides
AU2003304195B8 (en) 2002-07-15 2008-08-28 Board Of Regents, The University Of Texas System Combinatorial protein library screening by periplasmic expression
CA2492917C (en) 2002-07-19 2011-10-18 University Of South Carolina Compositions and methods for the modulation of gene expression in plants
CA2492544A1 (en) 2002-08-02 2004-02-12 Basf Plant Science Gmbh Modification of seed oil by the expression of a putative cytidyltransferase in transgenic plants
EP1529112A2 (en) 2002-08-07 2005-05-11 BASF Plant Science GmbH Nucleic acid sequences encoding proteins associated with abiotic stress response
KR20120002613A (ko) 2002-08-12 2012-01-06 제네렉스, 인코포레이티드 폭스바이러스 및 암과 관련된 방법 및 조성물
EP1597371A2 (en) 2003-02-17 2005-11-23 Metanomics GmbH Preparation of organisms with faster growth and/or higher yield
EP1594966B1 (en) 2003-02-20 2008-10-22 Athenix Corporation Delta-endotoxin genes and methods for their use
US7880061B2 (en) 2003-02-25 2011-02-01 The Curators Of The University Of Missouri Soybean variety SN97-6946
CA2517253C (en) 2003-02-27 2018-07-03 Basf Plant Science Gmbh Method for the production of polyunsaturated fatty acids
EP1613746B1 (de) 2003-03-31 2013-03-06 University Of Bristol Neue pflanzliche acyltransferasen spezifisch für langkettige, mehrfach ungesättigte fettsäuren
EP2194135A3 (en) 2003-04-15 2010-10-06 BASF Plant Science GmbH Nucleic acid sequences from yeast encoding proteins associated with abiotic stress response and transformed plant cells and plants with increased tolerance to environmental stress
TW200424214A (en) * 2003-04-21 2004-11-16 Advisys Inc Plasmid mediated GHRH supplementation for renal failures
PL1633875T3 (pl) 2003-05-28 2012-12-31 Basf Se Rośliny pszenicy o zwiększonej tolerancji na herbicydy imidazolinonowe
MXPA06002155A (es) 2003-08-29 2007-01-25 Inst Nac De Technologia Agrope Plantas de arroz que tienen una tolerancia incrementada a los herbicidas de imidazolinona.
US20050120415A1 (en) 2003-10-09 2005-06-02 E.I. Du Pont De Nemours And Company Gene silencing
WO2005063995A2 (en) 2003-12-23 2005-07-14 Basf Plant Science Gmbh Sugar and lipid metabolism regulators in plants vi
US20050220901A1 (en) * 2004-03-22 2005-10-06 Huttenbauer Samuel Jr Methods of pharmaceutical separation from plants
AU2005252338B2 (en) * 2004-06-07 2008-12-18 Basf Plant Science Gmbh Improved transformation of soybean
AU2005262493A1 (en) * 2004-06-16 2006-01-19 Basf Plant Science Gmbh Nucleic acid molecules encoding wrinkled1-like polypeptides and methods of use in plants
CN101124323A (zh) 2004-06-30 2008-02-13 先锋高级育种国际公司 保护植物免受致病真菌侵害的方法
BR122015026849C8 (pt) 2004-07-02 2017-06-20 Du Pont cassete de expressão, microorganismo transformado, método para indução de resistência a patógeno de planta em uma planta, composição anti-patogênica e método para proteção de uma planta contra um patógeno de planta
CN101001956B (zh) 2004-07-31 2014-09-24 梅坦诺米克斯有限公司 制备具有更快生长和/或更高产量的生物
WO2006013072A2 (en) 2004-08-02 2006-02-09 Basf Plant Science Gmbh Method for isolation of transcription termination sequences
EP1788861B1 (en) 2004-08-24 2017-04-12 Monsanto Technology, LLC Adenylate translocator protein gene non-coding regulatory elements for use in plants
EP2348117A1 (en) 2004-09-20 2011-07-27 BASF Plant Science GmbH Arabidopsis genes encoding proteins involved in sugar and lipid metabolism and methods of use
WO2006032708A2 (en) 2004-09-24 2006-03-30 Basf Plant Science Gmbh Nucleic acid sequences encoding proteins associated with abiotic stress response and plant cells and plants with increased tolerance to environmental stress
EP1794304B1 (en) 2004-09-24 2013-06-19 BASF Plant Science GmbH Plant cells and plants with increased tolerance to environmental stress
NZ582988A (en) 2004-10-21 2011-07-29 Venganza Inc Methods and materials for conferring resistance to pests and pathogens of plants
EP2302055B1 (en) 2004-11-12 2014-08-27 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
EP1831376A1 (en) 2004-12-28 2007-09-12 Pioneer Hi-Bred International, Inc. Improved grain quality through altered expression of seed proteins
US12570965B2 (en) 2005-03-02 2026-03-10 Instituto Nacional De Technologia Agropecuaria Herbicide-resistant rice plants, polynucleotides encoding herbicide-resistant acetohydroxyacid synthase large subunit proteins, and methods of use
EP2166100B1 (en) 2005-03-08 2012-07-18 BASF Plant Science GmbH Expression enhancing intron sequences
CA2600882C (en) * 2005-03-16 2013-02-26 Metabolix, Inc. Chemically inducible expression of biosynthetic pathways
CN101203611B (zh) 2005-04-19 2013-08-14 巴斯福植物科学有限公司 控制基因表达的改良方法
AU2006242193A1 (en) * 2005-05-02 2006-11-09 Purdue Research Foundation Methods for increasing the yield of fermentable sugars from plant stover
AR053269A1 (es) 2005-05-16 2007-04-25 Monsanto Technology Llc Plantas y semillas de maiz con mejoramiento de asparagina y proteina
CA2612016A1 (en) 2005-06-17 2006-12-21 Basf Plant Science Gmbh Lecitin-like protein kinase stress-related polypeptides and methods of use in plants
EA201301103A1 (ru) 2005-07-01 2014-02-28 Басф Се Резистентные к гербицидам растения подсолнечника, полинуклеотиды, кодирующие резистентные к гербицидам большие субъединицы белков ацетогидроксикислотной синтазы, и применение растений и полинуклеотидов
CN101228277B (zh) 2005-07-18 2013-11-27 巴斯福植物科学有限公司 过表达accdp基因的植物中的产量增加
EP1907555A2 (en) 2005-07-18 2008-04-09 BASF Plant Science GmbH Yield increase in plants overexpressing the shsrp genes
WO2007020198A2 (en) 2005-08-12 2007-02-22 Basf Plant Science Gmbh Nucleic acid sequences encoding proteins associated with abiotic stress response and plant cells and plants with increased tolerance to environmental stress
KR101772375B1 (ko) * 2005-09-07 2017-08-29 신라젠(주) Ｇｍ-ｃｓｆ를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법
WO2007030674A2 (en) * 2005-09-07 2007-03-15 Maxcyte, Inc. Use of nucleases to improve viability and enhance transgene expression in transfected cells
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
WO2007039454A1 (en) 2005-09-20 2007-04-12 Basf Plant Science Gmbh Methods for controlling gene expression using ta-siran
CN101356279A (zh) 2005-11-10 2009-01-28 先锋高级育种国际公司 Dof(具有一指的dna结合)序列和使用方法
EP2500422A3 (en) 2005-12-09 2012-12-19 BASF Plant Science GmbH Nucleic acid molecules encoding polypeptides involved in regulation of sugar and lipid metabolism and methods of use VIII
BRPI0706368A2 (pt) * 2006-01-06 2011-03-22 Univ Georgia composição, vetor, método para fornecer resistência ao cisto nematódeo a uma planta, proteìna de fusão, método para inibir atividade biológica, ácido nucléico isolado
US7663020B2 (en) * 2006-01-11 2010-02-16 Agrinomics Llc Generation of plants with altered oil content
AU2007281934B2 (en) 2006-01-18 2012-11-15 University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
US20070186313A1 (en) * 2006-01-31 2007-08-09 Pioneer Hi-Bred International, Inc. Method for high throughput transgene function analysis for agronomic traits in maize
US7868228B2 (en) 2006-01-31 2011-01-11 Monsanto Technology Llc Phosphopantetheinyl transferases from bacteria
US7820883B2 (en) 2006-03-15 2010-10-26 Dow Agrosciences Llc Resistance to auxinic herbicides
EP2343377A3 (en) 2006-03-24 2011-11-16 BASF Plant Science GmbH Proteins associated with abiotic stress response and homologs
AR060523A1 (es) 2006-04-19 2008-06-25 Pioneer Hi Bred Int Moleculas de polinucleotidos aislados que corresponden a alelos mutantes y tipo salvaje del gen de maiz d9 y metodos para usarlas
AR060563A1 (es) 2006-04-24 2008-06-25 Mendel Biotechnology Inc Promotores inducibles por enfermedad
EP2333088B1 (en) 2006-05-16 2013-08-28 Pioneer Hi-Bred International, Inc. Antifungal polypeptides
US20070271629A1 (en) 2006-05-17 2007-11-22 Pioneer Hi-Bred International, Inc. Artificial plant minichromosomes
ZA200900024B (en) 2006-06-29 2010-04-28 Mendel Biotechnology Inc Improved yield and stress tolerance in transgenic plants
US20100055113A1 (en) 2006-07-27 2010-03-04 The University Of Maryland, Baltimore Cellular receptor for antiproliferative factor
CA2659252A1 (en) 2006-08-07 2008-02-21 Mendel Biotechnology, Inc. Plants with enhanced size and growth rate
WO2009016433A2 (en) 2006-09-15 2009-02-05 Ottawa Health Research Institute Oncolytic rhabdovirus
EP2121938A2 (en) 2006-10-05 2009-11-25 E.I. Du Pont De Nemours And Company Maize microrna sequences
US8344205B2 (en) 2006-10-13 2013-01-01 Basf Plant Science Gmbh Plants with increased yield
CA2666968A1 (en) 2006-10-20 2008-10-30 Arizona Board Of Regents For And On Behalf Of Arizona State University Modified cyanobacteria
WO2008061157A2 (en) * 2006-11-15 2008-05-22 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
CA2669875C (en) 2006-11-15 2017-01-03 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
WO2008079545A2 (en) * 2006-11-15 2008-07-03 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
US8106253B2 (en) 2006-11-15 2012-01-31 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
CA2988382A1 (en) * 2006-11-15 2008-05-22 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
DK2102239T3 (da) 2006-11-30 2012-05-29 Res Dev Foundation Forbedrede immunoglobulin-biblioteker
BRPI0721171A2 (pt) * 2006-12-15 2014-03-18 Agrinomics Llc Produção de plantas com conteúdo alterado de óleos, proteínas ou fibras
WO2008076980A2 (en) 2006-12-15 2008-06-26 Agrigenetics, Inc. Generation of plants with altered oil, protein, or fiber content
MX2009006465A (es) * 2006-12-15 2009-08-21 Agrinomics Llc Generacion de plantas con contenido de aceite, proteina o fibra alterado.
MX2009006462A (es) * 2006-12-15 2009-08-21 Agrinomics Llc Generacion de plantas con contenido de aceite, proteina o fibra alterado.
WO2008076834A2 (en) * 2006-12-15 2008-06-26 Agrinomics Llc Generation of plants with altered oil, protein, or fiber content
KR20080084528A (ko) 2007-03-15 2008-09-19 제네렉스 바이오테라퓨틱스 인크. 종양살상형 백시니아 바이러스 암 치료
US8153863B2 (en) 2007-03-23 2012-04-10 New York University Transgenic plants expressing GLK1 and CCA1 having increased nitrogen assimilation capacity
CA2681515A1 (en) 2007-03-23 2008-10-02 Basf Plant Science Gmbh Transgenic plants with increased stress tolerance and yield expressing a lrp-2 protein
CA2682349C (en) 2007-04-04 2017-08-22 Basf Plant Science Gmbh Ahas mutants
KR20100016165A (ko) 2007-04-04 2010-02-12 바스프 에스이 제초제-저항성 브라시카 식물 및 사용 방법
US7723577B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN040847
US7723581B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN040845
US7728195B2 (en) * 2007-04-12 2010-06-01 Dow Agrosciences Llc Canola cultivar DN040856
US7723578B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN040839
US7723582B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN041100
US7718852B2 (en) * 2007-04-12 2010-05-18 Dow Agrosciences Llc Canola cultivar DN040241
AU2008240142B2 (en) 2007-04-12 2014-11-06 Corteva Agriscience Llc Novel canola cultivars having high yield and stabilized fatty acid profiles
US7723579B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN040244
US7723580B2 (en) * 2007-04-12 2010-05-25 Dow Agrosciences Llc Canola cultivar DN040844
EP2155789B1 (en) 2007-05-01 2013-07-24 Research Development Foundation Immunoglobulin fc libraries
WO2008135467A2 (en) 2007-05-04 2008-11-13 Basf Plant Science Gmbh Enhancement of seed oil / amino acid content by combinations of pyruvate kinase subunits
MX2009012556A (es) 2007-05-22 2010-02-18 Basf Plant Science Gmbh Plantas con mayor tolerancia y/o resistencia al estres ambiental y mayor produccion de biomasa.
US20100154076A1 (en) 2007-05-25 2010-06-17 Cropdesign N.V. Yield Enhancement In Plants By Modulation of Maize Alfins
BRPI0812060A2 (pt) 2007-05-29 2014-10-07 Basf Plant Science Gmbh Planta transgênica, polinucleotídeo isolado, polipeptídeo isolado, e, métodos para produzir uma planta transgênica e para aumentar o crescimento e/ou rendimento de planta sob condições normais ou de água limitada e/ou aumentar a tolerância da planta a um estresse ambiental
CN101715291A (zh) * 2007-06-18 2010-05-26 农业经济有限责任公司 具有改变的油、蛋白或纤维含量的植物的生产
EP2167666A2 (en) 2007-06-29 2010-03-31 Pioneer Hi-Bred International Inc. Methods for altering the genome of a monocot plant cell
CA2692650A1 (en) 2007-07-13 2009-01-22 Basf Plant Science Gmbh Transgenic plants with increased stress tolerance and yield
CA2694142A1 (en) 2007-08-02 2009-02-05 Basf Plant Science Gmbh Transgenic plants with increased stress tolerance and yield
JP5658564B2 (ja) 2007-08-31 2015-01-28 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物
AU2008300579B2 (en) 2007-09-18 2014-11-13 Basf Plant Science Gmbh Plants with increased yield
EP2193202A2 (en) 2007-09-21 2010-06-09 BASF Plant Science GmbH Plants with increased yield
CA2706799A1 (en) 2007-11-27 2009-06-04 Basf Plant Science Gmbh Transgenic plants with increased stress tolerance and yield
BRPI0821231A2 (pt) 2007-12-17 2014-12-23 Basf Plant Science Gmbh Polinucleotídeo, vetor , célula hospedeira, método para a fabricação de um polipeptídeo, polipeptídeo, anticorpo, organismo não humano transgênico, e, métodos para a fabricação de um lipídeo ou um ácido graxo e para a fabricação de uma planta.
EP2225380A2 (en) * 2007-12-17 2010-09-08 BASF Plant Science GmbH Lipid metabolism protein and uses thereof i (bzip transcription factor)
US8115055B2 (en) 2007-12-18 2012-02-14 E.I. Du Pont De Nemours And Company Down-regulation of gene expression using artificial microRNAs
US8937217B2 (en) 2007-12-18 2015-01-20 E. I. Du Pont De Nemours And Company Down-regulation of gene expression using artificial microRNAs
AU2008337398B2 (en) * 2007-12-19 2014-04-03 Basf Plant Science Gmbh Plants with increased yield and/or increased tolerance to environmental stress (IY-BM)
AR069917A1 (es) 2007-12-20 2010-03-03 Dow Agrosciences Llc Girasol con bajo contenido de grasas saturadas y metodos relacionados
BRPI0906429B1 (pt) 2008-01-10 2021-08-03 Research Development Foundation Método de identificação de uma infecção por e. chaffeensis em um indivíduo, uso de um ou mais polipeptídeo sintético e kit
US8367895B2 (en) 2008-01-17 2013-02-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides from the family aphididae
US8847013B2 (en) 2008-01-17 2014-09-30 Pioneer Hi Bred International Inc Compositions and methods for the suppression of target polynucleotides from lepidoptera
AU2009206225B2 (en) 2008-01-25 2015-04-23 Multivir Inc. p53 biomarkers
DE112009000313T5 (de) 2008-02-27 2011-04-28 Basf Plant Science Gmbh Pflanzen mit erhöhtem Ertrag
US8487159B2 (en) * 2008-04-28 2013-07-16 Metabolix, Inc. Production of polyhydroxybutyrate in switchgrass
US7947877B2 (en) * 2008-05-14 2011-05-24 Monosanto Technology LLC Plants and seeds of spring canola variety SCV328921
US7935870B2 (en) * 2008-05-14 2011-05-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV354718
US7964774B2 (en) * 2008-05-14 2011-06-21 Monsanto Technology Llc Plants and seeds of spring canola variety SCV384196
US8829282B2 (en) * 2008-05-14 2014-09-09 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV425044
EP3279314A1 (en) 2008-06-04 2018-02-07 Cellular Dynamics International, Inc. Methods for the production of ips cells using non-viral approach
CA2734128A1 (en) 2008-08-12 2010-02-18 Cellular Dynamics International, Inc. Methods for the production of ips cells
EP2328603A4 (en) 2008-08-18 2013-01-02 Univ Maryland APF DERIVATIVES AND USE METHOD
AU2009284172A1 (en) 2008-08-19 2010-02-25 Basf Plant Science Gmbh Plants with increased yield by increasing or generating one or more activities in a plant or a part thereof
DE112009001976T5 (de) 2008-08-20 2011-07-14 BASF Plant Science GmbH, 67063 Transgene Pflanzen mit erhöhtem Ertrag
WO2010034672A1 (en) 2008-09-23 2010-04-01 Basf Plant Science Gmbh Plants with increased yield (lt)
DE112009002213T5 (de) 2008-09-23 2011-07-28 BASF Plant Science GmbH, 67063 Transgene Pflanzen mit erhöhtem Ertrag
EP2341929B1 (en) 2008-10-06 2017-01-25 University Of Chicago Compositions and methods related to bacterial emp proteins
AR073855A1 (es) 2008-10-14 2010-12-09 Monsanto Technology Llc Utilizacion de desaturasas de acidos grasos de hemiselmis spp.
AU2009306575B2 (en) 2008-10-23 2016-04-14 Basf Plant Science Gmbh Plants with increased yield (NUE)
BRPI0924536A2 (pt) 2008-10-23 2015-08-11 Basf Plant Science Gmbh Método para produzir uma célula transgênica com teor de ácido gama-aminobutírico (gaba) aumentado, para aumentar o rendimento, molécula de ácido nucleico isolada, construção de ácido nucleico, vetor, célula hospedeira, processo para produzir um polipeptídeo, polipeptídeo, anticorpo, e, núcleo de célula, célula, núcleo de célula vegetal, célula vegetal, tecido vegetal, material de propagação, pólen, progênie, material coletado ou uma planta
JP2012507286A (ja) * 2008-11-04 2012-03-29 ダウ アグロサイエンシィズ エルエルシー オメガ９品質カラシナ
CA2743707A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
WO2010068738A1 (en) 2008-12-10 2010-06-17 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
WO2010084488A1 (en) 2009-01-20 2010-07-29 Ramot At Tel-Aviv University Ltd. Mir-21 promoter driven targeted cancer therapy
BRPI1005375A2 (pt) 2009-01-28 2016-08-09 Basf Plant Science Co Gmbh planta transgênica transformada com um cassete de expressão, semente e método para incrementar o rendimento de uma planta
AU2010209843A1 (en) 2009-01-28 2011-08-18 Basf Plant Science Company Gmbh Engineering NF-YB transcription factors for enhanced drought resistance and increased yield in transgenic plants
US8373025B2 (en) 2009-02-09 2013-02-12 Chromatin Germplasm, Llc Herbicide resistant sorghum
WO2010096510A2 (en) 2009-02-17 2010-08-26 Edenspace Systems Corporation Tempering of cellulosic biomass
WO2010102220A1 (en) 2009-03-05 2010-09-10 Metabolix, Inc. Propagation of transgenic plants
WO2010102293A1 (en) 2009-03-06 2010-09-10 Metabolix, Inc. Method of positive plant selection using sorbitol dehydrogenase
ES2717102T3 (es) 2009-03-19 2019-06-19 Dsm Ip Assets Bv Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos
CN102361988A (zh) 2009-03-23 2012-02-22 巴斯夫植物科学有限公司 具有改变的氧化还原机制和提高的产量的转基因植物
HUE026855T2 (en) 2009-04-03 2016-07-28 Univ Chicago Compositions and methods related to protein a (spa) variants
US8304616B2 (en) * 2009-04-07 2012-11-06 University Of Georgia Research Foundation, Inc. Soybean variety G00-3209
ES2568938T3 (es) 2009-04-28 2016-05-05 Vanderbilt University Composiciones y procedimientos de tratamiento de trastornos que implican apoptosis de células epiteliales
MX2011011678A (es) 2009-05-04 2011-12-06 Pioneer Hi Bred Int Mejora de la produccion en plantas mediante la modulacion del factor de transcripcion ap2.
US20100299773A1 (en) * 2009-05-20 2010-11-25 Monsanto Technology Llc Methods and compositions for selecting an improved plant
WO2010138971A1 (en) 2009-05-29 2010-12-02 Edenspace Systems Corporation Plant gene regulatory elements
WO2010141801A2 (en) 2009-06-05 2010-12-09 Cellular Dynamics International, Inc. Reprogramming t cells and hematophietic cells
MX2011013224A (es) 2009-06-09 2012-06-01 Pioneer Hi Bred Int Promotor de endospermo temprano y metodos de uso.
US8071848B2 (en) * 2009-06-17 2011-12-06 Monsanto Technology Llc Plants and seeds of spring canola variety SCV218328
US20120117867A1 (en) 2009-07-23 2012-05-17 Basf Plant Science Company Gmbh Plants with Increased Yield
BR112012002454A2 (pt) 2009-08-05 2017-07-04 Chromocell Corp plantas, micróbios e organismos melhorados
MX2012002189A (es) 2009-08-21 2012-03-16 Beeologics Inc Prevencion y cura de las enfermedades de los insectos beneficiosos a traves de moleculas.
CA2772298A1 (en) 2009-08-26 2011-03-03 Research Development Foundation Methods for creating antibody libraries
EP3401404A1 (en) 2009-08-28 2018-11-14 E. I. du Pont de Nemours and Company Compositions and methods to control insect pests
ES2848650T3 (es) 2009-09-14 2021-08-11 Sillajen Biotherapeutics Inc Terapia combinada contra el cáncer con virus vaccinia oncolítico
WO2011034945A1 (en) 2009-09-15 2011-03-24 Metabolix, Inc. Generation of high polyhydroxybutrate producing oilseeds
WO2011050271A1 (en) 2009-10-23 2011-04-28 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
BR112012009044A2 (pt) 2009-10-26 2015-09-01 Pioneer Hi Bred Int Molécula de ácido nucléico isolada, cassete de expressão, vetor, célula vegetal, planta, semente transgênica, método para expressão de um polinucleotídeo em uma planta ou célula vegetal e método para expressão de um polinucleotídeo, preferencialmente em tecidos somáticos de óvulo de uma planta
US20120227134A1 (en) 2009-11-17 2012-09-06 Basf Plant Science Company Gmbh Plants with Increased Yield
WO2011070440A2 (en) 2009-12-10 2011-06-16 Ottawa Hospital Research Institute Oncolytic rhabdovirus
AU2010339404B2 (en) 2009-12-30 2016-01-28 Pioneer Hi-Bred International, Inc. Methods and compositions for the introduction and regulated expression of genes in plants
WO2011082310A2 (en) 2009-12-30 2011-07-07 Pioneer Hi-Bred International, Inc. Methods and compositions for targeted polynucleotide modification
CA2788198C (en) 2010-01-26 2021-01-19 Pioneer Hi-Bred International, Inc. Hppd-inhibitor herbicide tolerance
WO2011100508A2 (en) 2010-02-12 2011-08-18 Arizona Board Of Regents For And On Behalf Of Arizona State University Methods and compositions related to glycoprotein-immunoglobulin fusions
ES2576061T3 (es) 2010-02-25 2016-07-05 Dana-Farber Cancer Institute, Inc. Mutaciones de BRAF que confieren resistencia a inhibidores de BRAF
US8148611B2 (en) * 2010-02-26 2012-04-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV453784
US8138394B2 (en) * 2010-02-26 2012-03-20 Monsanto Technology Llc Plants and seeds of spring canola variety SCV431158
US8143488B2 (en) * 2010-02-26 2012-03-27 Monsanto Technoloy LLC Plants and seeds of spring canola variety SCV470336
EP2542678B1 (en) 2010-03-04 2017-04-12 InteRNA Technologies B.V. A MiRNA MOLECULE DEFINED BY ITS SOURCE AND ITS THERAPEUTIC USES IN CANCER ASSOCIATED WITH EMT
BR112012022218A2 (pt) 2010-03-04 2018-07-10 Mendel Biotechnology Inc reguladores de transcrição para melhorar desempenho de planta
US8581048B2 (en) * 2010-03-09 2013-11-12 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV119103
US8153865B2 (en) * 2010-03-11 2012-04-10 Monsanto Technology Llc Plants and seeds of spring canola variety SCV152154
EP2555794A4 (en) 2010-04-05 2014-01-15 Univ Chicago COMPOSITIONS AND METHODS RELATING TO PROTEIN A (SPA) ANTIBODIES AS IMMUNE REACTION AMPLIFIERS
WO2011126976A1 (en) 2010-04-07 2011-10-13 Vanderbilt University Reovirus vaccines and methods of use therefor
WO2011133512A1 (en) 2010-04-19 2011-10-27 Research Development Foundation Rtef-1 variants and uses thereof
MX2012012211A (es) 2010-04-23 2012-12-17 Du Pont Composiciones de interruptores genicos y metodos de uso de las mismas.
CA2798067A1 (en) 2010-05-04 2011-11-24 Basf Se Plants having increased tolerance to herbicides
MX2012012672A (es) 2010-05-06 2012-12-17 Du Pont Gen y proteina acc sintasa 3 de maiz y sus usos.
BR112012029422A2 (pt) 2010-05-19 2017-10-03 The Samuel Roberts Noble Found Inc Morfologia de folha alterada e propriedades agronômicas melhoradas em plantas
PT2580322T (pt) 2010-06-09 2018-03-01 Dana Farber Cancer Inst Inc Uma mutação em mek1 que confere resistência aos inibidores de raf e mek
EP2582793B1 (en) 2010-06-15 2017-09-06 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
WO2011159684A2 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. Generation of induced pluripotent stem cells from small volumes of peripheral blood
FR2961375B1 (fr) 2010-06-16 2016-05-13 Inst De Rech Pour Le Dev (Ird) Surproduction d'acide jasmonique dans des plantes transgeniques
BR112012032907A2 (pt) 2010-06-25 2017-06-13 Du Pont métodos para selecionar e identificar uma planta de mais e planta de mais
CA2803298C (en) 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
EP2591106A1 (en) 2010-07-06 2013-05-15 InteRNA Technologies B.V. Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
WO2012006440A2 (en) 2010-07-07 2012-01-12 Cellular Dynamics International, Inc. Endothelial cell production by programming
CA2806858C (en) 2010-08-04 2021-06-15 Cellular Dynamics International, Inc. Reprogramming immortalized b cells
BR112013003135A2 (pt) 2010-08-13 2017-11-07 Pioneer Hi Bred Int polinucletídeo e polipeptídeo isolado ou recombinante, construto de ácido nucleico, célula, planta, explante vegetal, semente transgênica, método para produção de célula vegetal para controle de plantas daninhas e para detecção de um polipeptídeo hppd e um polinucleotídeo.
BR112013003223A2 (pt) 2010-08-23 2016-06-07 Pioneer Hi Bred Int "polinucleotídeo isolado, cassete de expressão, célula hospedeira, micro-organismo, planta ou parte de planta, método de obtenção de uma planta transformada, composição antipatogênica, método para proteger uma planta contra um patógeno ou uso de um polinucleotídeo isolado"
CN103080127A (zh) 2010-09-01 2013-05-01 先锋国际良种公司 液泡靶向肽及使用方法
EP2614074A1 (en) 2010-09-09 2013-07-17 The University of Chicago Methods and compositions involving protective staphylococcal antigens
BR112013005973A2 (pt) 2010-09-15 2019-09-24 Metabolix Inc aumento do fluxo de carbono para a produção de poli-hidroxibutirato em culturas de biomassa
EP3536337A1 (en) 2010-09-22 2019-09-11 The Regents of the University of Colorado, a body corporate Therapeutic applications of smad7
US9045549B2 (en) 2010-11-03 2015-06-02 The Samuel Roberts Noble Foundation, Inc. Transcription factors for modification of lignin content in plants
US11274313B2 (en) 2010-12-16 2022-03-15 BASF Agro B.V. Plants having increased tolerance to herbicides
EP2655635A1 (en) 2010-12-22 2013-10-30 Pioneer Hi-Bred International, Inc. Viral promoter, truncations thereof, and methods of use
CN103261425B (zh) 2010-12-22 2015-07-15 先锋国际良种公司 病毒启动子、其截短物以及使用方法
MX2013007532A (es) 2010-12-28 2013-09-16 Pioneer Hi Bred Int Nuevo gen de bacillus thuringiensis con actividad contra el orden lepidoptera.
AU2012204467B2 (en) 2011-01-04 2016-08-18 Sillajen, Inc. Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus
EP2474617A1 (en) 2011-01-11 2012-07-11 InteRNA Technologies BV Mir for treating neo-angiogenesis
AR084844A1 (es) 2011-01-14 2013-06-26 Jones Jeffrey B Arboles de citricos con resistencia a cancro de los citricos
US9578880B2 (en) 2011-02-01 2017-02-28 Colorado Wheat Research Foundation, Inc. Acetyl co-enzyme A carboxylase herbicide resistant plants
US8952132B2 (en) 2011-02-07 2015-02-10 Research Development Foundation Engineered immunoglobulin FC polypeptides
CA2826386C (en) 2011-02-08 2020-04-28 FUJIFILM Cellular Dynamics, Inc. Hematopoietic precursor cell production by programming
CN103459601A (zh) 2011-02-11 2013-12-18 先锋国际良种公司 具有对抗玉米根虫的活性的合成杀昆虫蛋白
EP2675900B1 (en) 2011-02-15 2017-09-06 Pioneer Hi-Bred International, Inc. Root-preferred promoter and methods of use
US8878007B2 (en) 2011-03-10 2014-11-04 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
CA2831144A1 (en) 2011-03-23 2012-09-27 Pioneer Hi-Bred International, Inc. Methods for producing a complex transgenic trait locus
EP2794887A2 (en) 2011-03-30 2014-10-29 Universidad Nacional Autonoma De Mexico Mutant bacillus thuringiensis cry genes and methods of use
US8513487B2 (en) 2011-04-07 2013-08-20 Zenon LISIECZKO Plants and seeds of spring canola variety ND-662c
US8513494B2 (en) 2011-04-08 2013-08-20 Chunren Wu Plants and seeds of spring canola variety SCV695971
US9085631B2 (en) 2011-04-08 2015-07-21 Nov Vac APS Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
WO2012142311A1 (en) 2011-04-15 2012-10-18 Pioneer Hi-Bred International, Inc. Self-reproducing hybrid plants
US8507761B2 (en) 2011-05-05 2013-08-13 Teresa Huskowska Plants and seeds of spring canola variety SCV372145
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
US8901371B2 (en) 2011-05-06 2014-12-02 The Samuel Roberts Noble Foundation, Inc. Compositions and methods for improved plant feedstock
US9062317B2 (en) 2011-05-09 2015-06-23 E I Du Pont De Nemours And Company Methods and compositions for silencing gene families using artificial microRNAs
US8513495B2 (en) 2011-05-10 2013-08-20 Dale Burns Plants and seeds of spring canola variety SCV291489
US9150625B2 (en) 2011-05-23 2015-10-06 E I Du Pont De Nemours And Company Chloroplast transit peptides and methods of their use
EP2718427B1 (en) 2011-06-08 2017-01-11 Children's Hospital of Eastern Ontario Research Institute Inc. Compositions for glioblastoma treatment
CA2844470A1 (en) 2011-06-21 2013-05-10 Pioneer Hi-Bred International, Inc. Methods and compositions for producing male sterile plants
WO2013006861A1 (en) 2011-07-07 2013-01-10 University Of Georgia Research Foundation, Inc. Sorghum grain shattering gene and uses thereof in altering seed dispersal
JP2014520551A (ja) 2011-07-11 2014-08-25 セルラー ダイナミクス インターナショナル， インコーポレイテッド 細胞のリプログラミング方法およびゲノムの改変方法
WO2013009935A2 (en) 2011-07-12 2013-01-17 Two Blades Foundation Late blight resistance genes
EP2739739A1 (en) 2011-08-03 2014-06-11 E. I. Du Pont de Nemours and Company Methods and compositions for targeted integration in a plant
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
WO2013024121A2 (en) 2011-08-18 2013-02-21 Basf Plant Science Company Gmbh Increase of sucrose transporter activity in the seeds of plants
WO2013026015A1 (en) 2011-08-18 2013-02-21 Dana-Farber Cancer Institute, Inc. Muc1 ligand traps for use in treating cancers
US11377663B1 (en) 2011-08-30 2022-07-05 Monsanto Technology Llc Genetic regulatory elements
US12188028B1 (en) 2011-08-30 2025-01-07 Monsanto Technology, Llc Methods for making genetic regulatory elements
BR112014004812A2 (pt) 2011-08-31 2018-10-23 Du Pont métodos para regenerar uma planta e para produzir uma planta transformada
EP2766388A1 (en) 2011-10-12 2014-08-20 Møller, Niels Iversen Peptides derived from campylobacter jejuni and their use in vaccination
CA2850390A1 (en) 2011-10-28 2013-05-02 E. I. Du Pont De Nemours And Company Methods and compositions for silencing genes using artificial micrornas
WO2013063344A1 (en) 2011-10-28 2013-05-02 Pioneer Hi-Bred International, Inc. Engineered pep carboxylase variants for improved plant productivity
US20140182011A1 (en) 2011-11-03 2014-06-26 The University Of Hong Kong Methods Using Acyl-Coenzyme A-Binding Proteins to Enchance Drought Tolerance in Genetically Modified Plants
FR2984076A1 (fr) 2011-12-15 2013-06-21 Inst Rech Developpement Ird Surproduction de jasmonates dans des plantes transgeniques
EP3369818B1 (en) 2011-12-22 2021-06-09 InteRNA Technologies B.V. Mirna for treating head and neck cancer
WO2013103365A1 (en) 2012-01-06 2013-07-11 Pioneer Hi-Bred International, Inc. Pollen preferred promoters and methods of use
WO2013103366A1 (en) 2012-01-06 2013-07-11 Pioneer Hi-Bred International, Inc. A method to screen plants for genetic elements inducing parthenogenesis in plants
EP2800816A1 (en) 2012-01-06 2014-11-12 Pioneer Hi-Bred International Inc. Ovule specific promoter and methods of use
CA2860611A1 (en) 2012-01-06 2013-07-11 Pioneer Hi-Bred International, Inc. Compositions and methods for the expression of a sequence in a reproductive tissue of a plant
BR112014018009A2 (pt) 2012-01-23 2018-06-26 Du Pont sequência de ácido nucleico isolada, construção recombinante, célula vegetal, método para reduzir a expressão de pelo menos um gene biossintético de ácido graxo vegetal, método para reduzir a expressão de dois ou mais genes biossintéticos de ácido graxo vegetal e planta ou semente transgênica
BR112014018294B1 (pt) 2012-01-26 2022-01-11 Norfolk Plant Sciences, Ltd Método para produzir uma planta, cassete de expressão, e, célula bacteriana
AR089793A1 (es) 2012-01-27 2014-09-17 Du Pont Metodos y composiciones para generar locus de rasgos transgenicos complejos
US8859857B2 (en) 2012-04-26 2014-10-14 Monsanto Technology Llc Plants and seeds of spring canola variety SCV259778
JP6670106B2 (ja) 2012-04-26 2020-03-18 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ ブドウ球菌コアグラーゼ抗原およびその使用方法
US8835720B2 (en) 2012-04-26 2014-09-16 Monsanto Technology Llc Plants and seeds of spring canola variety SCV967592
CN104703622B (zh) 2012-04-26 2017-05-24 芝加哥大学 与金黄色葡萄球菌疾病期间抵消凝固酶活性的抗体相关的组合物和方法
US8802935B2 (en) 2012-04-26 2014-08-12 Monsanto Technology Llc Plants and seeds of spring canola variety SCV942568
US8878009B2 (en) 2012-04-26 2014-11-04 Monsanto Technology, LLP Plants and seeds of spring canola variety SCV318181
US20150184173A1 (en) 2012-05-04 2015-07-02 E I Du Pont De Nemours And Company Compositions and methods comprising sequences having meganuclease activity
US10045499B2 (en) 2012-05-24 2018-08-14 Iowa State University Research Foundation, Inc. Arabidopsis nonhost resistance gene(s) and use thereof to engineer disease resistant plants
US12565524B2 (en) 2012-05-29 2026-03-03 North Carolina Central University Methods for the production of cytoprotective asialo-erythropoietin in plants and its purification from plant tissues
WO2013184768A1 (en) 2012-06-05 2013-12-12 University Of Georgia Research Foundation, Inc. Compositions and methods of gene silencing in plants
BR112014031260A2 (pt) 2012-06-15 2019-08-20 Du Pont métodos e composições que envolvem variantes de als com preferência de substrato nativo
US9347105B2 (en) 2012-06-15 2016-05-24 Pioneer Hi Bred International Inc Genetic loci associated with resistance of soybean to cyst nematode and methods of use
AR091489A1 (es) 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
US20150211019A1 (en) 2012-08-13 2015-07-30 University Of Georgia Research Foundation, Inc. Compositions and Methods for Increasing Pest Resistance in Plants
US9587247B2 (en) 2012-08-16 2017-03-07 Wisconsin Alumni Research Foundation Plants with altered phytochromes
US20150240253A1 (en) 2012-08-30 2015-08-27 E. I. Du Pont De Nemours And Company Long intergenic non-coding rnas in maize
EP3622810B1 (en) 2012-09-24 2024-01-03 Seminis Vegetable Seeds, Inc. Methods and compositions for extending shelf life of plant products
WO2014059155A1 (en) 2012-10-11 2014-04-17 Pioneer Hi-Bred International, Inc. Guard cell promoters and uses thereof
CN104884625A (zh) 2012-10-15 2015-09-02 先锋国际良种公司 增强cry内毒素的活性的方法和组合物
US9890216B2 (en) 2012-10-23 2018-02-13 Board Of Regents, The University Of Texas System Antibodies with engineered IgG Fc domains
EP2917348A1 (en) 2012-11-06 2015-09-16 InteRNA Technologies B.V. Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated b-raf pathway
JP6457945B2 (ja) 2012-11-23 2019-01-23 ヘキシマ リミテッドＨｅｘｉｍａ Ｌｉｍｉｔｅｄ 抗病原体方法
US20140173775A1 (en) 2012-12-13 2014-06-19 Pioneer Hi-Bred International, Inc. Methods and compositions for producing and selecting transgenic plants
BR112015012645A2 (pt) 2012-12-18 2018-10-23 Basf Se métodos para produção, molécula e constructo de ácido nucleico, vetor, polipeptídeo, núcleo de célula vegetal, planta transgênica, processo, composição, uso do ácido nucleico e método para controlar ervas daninhas
BR112015015055A2 (pt) 2012-12-21 2017-10-03 Pioneer Hi Bred Int Método para desintoxicar um herbicida análogo de auxina, método para controlar pelo menos uma erva em uma área de cultivo, método para testar uma resposta de planta a um ou mais compostos
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
JP2016513115A (ja) 2013-02-21 2016-05-12 チルドレンズ ホスピタル オブ イースタン オンタリオ リサーチ インスティチュート インコーポレイテッド ワクチン組成物
CN105229144A (zh) 2013-02-22 2016-01-06 细胞动力学国际有限公司 通过组合的遗传工程和化学工程经由正向编程产生肝细胞
WO2014134144A1 (en) 2013-02-28 2014-09-04 The General Hospital Corporation Mirna profiling compositions and methods of use
WO2014132137A2 (en) 2013-03-01 2014-09-04 Université De Genève Transgenic cell selection
US10456448B2 (en) 2013-03-08 2019-10-29 The Regents Of The University Of Colorado, A Body Corporate PTD-SMAD7 therapeutics
WO2014164775A1 (en) 2013-03-11 2014-10-09 Pioneer Hi-Bred International, Inc. Methods and compositions to improve the spread of chemical signals in plants
CA2905399A1 (en) 2013-03-11 2014-10-09 Pioneer Hi-Bred International, Inc. Methods and compositions employing a sulfonylurea-dependent stabilization domain
US9803214B2 (en) 2013-03-12 2017-10-31 Pioneer Hi-Bred International, Inc. Breeding pair of wheat plants comprising an MS45 promoter inverted repeat that confers male sterility and a construct that restores fertility
RU2694686C2 (ru) 2013-03-12 2019-07-16 Е.И.Дюпон Де Немур Энд Компани Способы идентификации вариантных сайтов распознавания для редкощепящих сконструированных средств для индукции двунитевого разрыва, и композиции с ними, и их применения
US9243258B2 (en) 2013-03-12 2016-01-26 Pioneer Hi Bred International Inc Root-preferred promoter and methods of use
US9273322B2 (en) 2013-03-12 2016-03-01 Pioneer Hi Bred International Inc Root-preferred promoter and methods of use
US9416368B2 (en) 2013-03-13 2016-08-16 E I Du Pont De Nemours And Company Identification of P. pachyrhizi protein effectors and their use in producing Asian soybean rust (ASR) resistant plants
BR112015023272A2 (pt) 2013-03-14 2017-07-18 Pioneer Hi Bred Int célula vegetal, planta, explante vegetal, semente transgênica, método para produzir uma célula vegetal tendo um polinucleotídeo heterólogo que codifica um polipeptídeo tendo atividade de dicamba descarboxilase, método para controlar plantas daninhas em um campo contendo uma cultura e método para controlar plantas daninhas em um campo contendo uma cultura
WO2014153254A2 (en) 2013-03-14 2014-09-25 Pioneer Hi-Bred International Inc. Compositions and methods to control insect pests
AU2014236162A1 (en) 2013-03-14 2015-09-17 Arzeda Corp. Compositions having dicamba decarboxylase activity and methods of use
CA2901316A1 (en) 2013-03-15 2014-09-25 Pioneer Hi-Bred International, Inc. Phi-4 polypeptides and methods for their use
US20140380524A1 (en) 2013-06-19 2014-12-25 The University Of Hong Kong Methods of using 3-hydroxy-3-methylglutaryl-coa synthase to enhance growth and/or seed yield of genetically modified plants
US11459579B2 (en) 2013-07-09 2022-10-04 Board Of Trustees Of Michigan State University Transgenic plants produced with a K-domain, and methods and expression cassettes related thereto
US10570409B2 (en) 2013-07-09 2020-02-25 Board Of Trustees Of Michigan State University Transgenic plants produced with a K-domain, and methods and expression cassettes related thereto
EP3030072B1 (en) 2013-08-08 2020-03-04 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having broad spectrum activity and uses thereof
US10968462B2 (en) 2013-08-12 2021-04-06 BASF Agro B.V. Plants having increased tolerance to herbicides
CA2920590C (en) 2013-08-12 2023-12-05 BASF Agro B.V. Plants having increased tolerance to herbicides
BR112016003225B1 (pt) 2013-08-16 2022-10-25 Pioneer Hi-Bred International, Inc. Polipeptídeo pip-47, polipeptídeo pip-47 quimérico, composição, proteína de fusão, método para controlar uma população de inseto-praga, método para inibir o crescimento ou matar um inseto-praga, construto de dna, polinucleotídeo isolado, cassete de expressão, método de obtenção de uma planta transgênica e método para controlar infestação de inseto
CN120574876A (zh) 2013-08-22 2025-09-02 纳幕尔杜邦公司 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法
EP3043825A4 (en) 2013-09-09 2017-05-03 Figene, LLC Gene therapy for the regeneration of chondrocytes or cartilage type cells
US20160201073A1 (en) 2013-09-11 2016-07-14 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
BR122020001770B1 (pt) 2013-09-13 2022-11-29 Pioneer Hi-Bred International, Inc Construto de dna, método de obtenção de planta transgênica, proteína de fusão, método para controlar uma população de praga de inseto, método para inibir o crescimento ou matar uma praga de inseto
US10329578B2 (en) 2013-10-18 2019-06-25 Pioneer Hi-Bred International, Inc. Glyphosate-N-acetyltransferase (GLYAT) sequences and methods of use
US20160249542A1 (en) 2013-10-29 2016-09-01 Pioneer Hi-Bred International Inc. Self-reproducing hybrid plants
US20170002064A1 (en) 2013-11-08 2017-01-05 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
CA2929555A1 (en) 2013-11-08 2015-05-14 Baylor Research Institute Nuclear localization of glp-1 stimulates myocardial regeneration and reverses heart failure
EP3077820B1 (en) 2013-12-03 2025-02-26 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
WO2015116753A1 (en) 2014-01-29 2015-08-06 Dana-Farber Cancer Institute, Inc. Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
US20170166920A1 (en) 2014-01-30 2017-06-15 Two Blades Foundation Plants with enhanced resistance to phytophthora
CN106536545B (zh) 2014-02-07 2026-03-03 先锋国际良种公司 杀昆虫蛋白及其使用方法
BR112016018103B1 (pt) 2014-02-07 2024-01-16 E.I. Du Pont De Nemours And Company Polipeptídeo e seu uso, polinucleotídeo, composição, proteína de fusão, método para controlar uma população, método para inibir o crescimento, método para controlar a infestação, método para obtenção de uma planta ou célula vegetal, construto
WO2015123561A2 (en) 2014-02-14 2015-08-20 University Of Utah Research Foundation Methods and compositions for inhibiting retinopathy of prematurity
WO2015130783A1 (en) 2014-02-25 2015-09-03 Research Development Foundation Sty peptides for inhibition of angiogenesis
WO2015153932A1 (en) 2014-04-02 2015-10-08 Wisconsin Alumni Research Foundation Improved strategy to engineer phytochromes with improved action in crop fields
WO2015150465A2 (en) 2014-04-03 2015-10-08 Basf Se Plants having increased tolerance to herbicides
US20170107486A1 (en) 2014-04-21 2017-04-20 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
WO2015171603A1 (en) 2014-05-06 2015-11-12 Two Blades Foundation Methods for producing plants with enhanced resistance to oomycete pathogens
CN106661584B (zh) 2014-07-10 2020-08-11 本森希尔生物系统股份有限公司 用于增加植物生长和产量的方法和组合物
US10676754B2 (en) 2014-07-11 2020-06-09 E I Du Pont De Nemours And Company Compositions and methods for producing plants resistant to glyphosate herbicide
CA2955828A1 (en) 2014-08-08 2016-02-11 Pioneer Hi-Bred International, Inc. Ubiquitin promoters and introns and methods of use
MX2017002930A (es) 2014-09-12 2017-06-06 Du Pont Generacion de sitios de integracion especifica de sitio para loci de rasgos complejos en maiz y soja, y metodos de uso.
WO2016044092A1 (en) 2014-09-17 2016-03-24 Pioneer Hi Bred International Inc Compositions and methods to control insect pests
CN107072165B (zh) 2014-09-26 2021-05-28 先锋国际良种公司 小麦Ms1多核苷酸、多肽以及使用方法
WO2016049531A1 (en) 2014-09-26 2016-03-31 Purecircle Usa Inc. Single nucleotide polymorphism (snp) markers for stevia
UA124757C2 (uk) 2014-10-16 2021-11-17 Піонір Хай-Бред Інтернешнл, Інк. Інсектицидний поліпептид проти лускокрилого або твердокрилого шкідника та його застосування
CN114736275A (zh) 2014-10-16 2022-07-12 先锋国际良种公司 具有改进的活性谱的杀昆虫多肽及其用途
CN113372421B (zh) 2014-10-16 2024-08-06 先锋国际良种公司 杀昆虫蛋白及其使用方法
WO2016077624A1 (en) 2014-11-12 2016-05-19 Nmc, Inc. Transgenic plants with engineered redox sensitive modulation of photosynthetic antenna complex pigments and methods for making the same
EP3777883A1 (en) 2014-11-13 2021-02-17 Evaxion Biotech ApS Peptides derived from acinetobacter baumannii and their use in vaccination
WO2016100309A1 (en) 2014-12-16 2016-06-23 Pioneer Hi-Bred International, Inc. Restoration of male fertility in wheat
US10947556B2 (en) 2014-12-19 2021-03-16 AgBiome, Inc. Sequences to facilitate incorporation of DNA into the genome of an organism
WO2016113252A2 (en) 2015-01-12 2016-07-21 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting klebsiella pneumoniae
CN114075267B (zh) 2015-01-15 2025-03-18 先锋国际良种公司 杀昆虫蛋白及其使用方法
AU2016209901B2 (en) 2015-01-21 2021-12-02 Basf Se Plants having increased tolerance to herbicides
US20180002656A1 (en) 2015-01-28 2018-01-04 Sabic Global Technologies B.V. Methods and compositions for high-efficiency production of biofuel and/or biomass
WO2016130516A1 (en) 2015-02-09 2016-08-18 Research Development Foundation Engineered immunoglobulin fc polypeptides displaying improved complement activation
AR103649A1 (es) 2015-02-11 2017-05-24 Basf Se Hidroxifenilpiruvato dioxigenasas resistentes a herbicidas
EP3259346B1 (en) 2015-02-20 2024-08-07 Baylor College of Medicine P63 inactivation for the treatment of heart failure
WO2016137774A1 (en) 2015-02-25 2016-09-01 Pioneer Hi-Bred International Inc Composition and methods for regulated expression of a guide rna/cas endonuclease complex
CA2977026A1 (en) 2015-03-11 2016-09-15 E.I. Du Pont De Nemours And Company Insecticidal combinations of pip-72 and methods of use
EP4118955A1 (en) 2015-03-19 2023-01-18 Pioneer Hi-Bred International, Inc. Compositions for accelerated trait introgression
US11174467B2 (en) 2015-04-08 2021-11-16 Yield10 Bioscience, Inc. Plants with enhanced yield and methods of construction
BR112017024024A2 (pt) 2015-05-08 2018-11-27 Benson Hill Biosystems Inc métodos para aumentar crescimento de planta e rendimento usando- se uma sequência de ictb
CN107709564B (zh) 2015-05-09 2021-11-02 双刃基金会 来自少花龙葵的抗晚疫病基因及使用方法
AU2016263026A1 (en) 2015-05-15 2017-11-09 Pioneer Hi-Bred International, Inc. Guide RNA/Cas endonuclease systems
CA2985198A1 (en) 2015-05-19 2016-11-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3310803A1 (en) 2015-06-16 2018-04-25 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CA2989531A1 (en) 2015-06-17 2016-12-22 BASF Agro B.V. Plants having increased tolerance to herbicides
EP4116316A1 (en) 2015-07-04 2023-01-11 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa
BR112018002535A2 (pt) 2015-08-06 2018-09-25 Du Pont polipeptídeo inseticida recombinante, polinucleotídeo recombinante, construto de dna, planta transgênica ou célula de planta, composição, proteína de fusão, método para controlar uma praga, método para inibir crescimento ou para exterminar uma população de pragas ou uma praga e uso do polipeptídeo
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
WO2017062790A1 (en) 2015-10-09 2017-04-13 Two Blades Foundation Cold shock protein receptors and methods of use
EP4144844B1 (en) 2015-10-12 2025-09-10 DuPont US Holding, LLC Protected dna templates for gene modification and increased homologous recombination in cells and methods of use
WO2021257206A1 (en) 2020-06-17 2021-12-23 Pioneer Hi-Bred International, Inc. Generating maize plants with enhanced resistance to northern leaf blight
WO2017066597A1 (en) 2015-10-16 2017-04-20 Pioneer Hi-Bred International, Inc. Generating maize plants with enhanced resistance to northern leaf blight
BR112018008134A2 (pt) 2015-10-20 2018-11-06 Pioneer Hi Bred Int método para restaurar a função de um produto gênico não funcional no genoma de uma célula, método para editar uma sequência nucleotídica no genoma de uma célula, planta ou planta de progênie, método para editar uma sequência nucleotídica no genoma de uma célula sem o uso de um molde polinucleotídico de modificação e método para entregar um complexo de rna guia/endonuclease cas numa célula
US10947502B2 (en) 2015-10-20 2021-03-16 FUJIFILM Cellular Dynamics, Inc. Methods for directed differentiation of pluripotent stem cells to immune cells
WO2017068544A1 (en) 2015-10-22 2017-04-27 Basf Se Plants having increased tolerance to herbicides
WO2017068543A1 (en) 2015-10-22 2017-04-27 Basf Se Plants having increased tolerance to herbicides
WO2017070458A2 (en) 2015-10-23 2017-04-27 Donald Danforth Plant Science Center Genes encoding c4 transporter proteins for use in increasing crop plant yield
SG11201803419PA (en) 2015-10-30 2018-05-30 The Regents Of The Universtiy Of California Methods of generating t-cells from stem cells and immunotherapeutic methods using the t-cells
ES2892972T3 (es) 2015-11-02 2022-02-07 Univ Texas Métodos de activación de CD40 y bloqueo de punto de control inmunitario
WO2017079026A1 (en) 2015-11-06 2017-05-11 E. I. Du Pont De Nemours And Company Generation of complex trait loci in soybean and methods of use
WO2017079746A2 (en) 2015-11-07 2017-05-11 Multivir Inc. Methods and compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
RS65666B1 (sr) 2015-11-09 2024-07-31 Childrens Hospital Philadelphia Glipikan 2 kao tumor marker i terapijski cilj
BR112018011174A2 (pt) 2015-11-30 2018-11-21 Du Pont polinucleotídeo recombinante, construto de dna, célula heteróloga, planta transgênica ou célula de planta, semente da planta transgênica, método para expressar um polinucleotídeo em uma planta e método para aprimorar a transcrição de um polinucleotídeo em uma célula hospedeira
DK3387134T3 (da) 2015-12-11 2020-12-21 Danisco Us Inc Fremgangsmåder og sammensætninger til øget nukleasemedieret genommodifikation og reducerede virkninger uden for målstedet
WO2017106414A1 (en) 2015-12-18 2017-06-22 Danisco Us Inc. Methods and compositions for polymerase ii (pol-ii) based guide rna expression
EP3390631B1 (en) 2015-12-18 2020-04-08 Danisco US Inc. Methods and compositions for t-rna based guide rna expression
CA3004056C (en) 2015-12-22 2024-01-23 Pioneer Hi-Bred International, Inc. Tissue-preferred promoters and methods of use
US20190338302A1 (en) 2016-02-04 2019-11-07 Yield10 Bioscience, Inc. Transgenic land plants comprising a putative transporter protein of an edible eukaryotic algae
US9896696B2 (en) 2016-02-15 2018-02-20 Benson Hill Biosystems, Inc. Compositions and methods for modifying genomes
EP3419654B1 (en) 2016-02-22 2022-04-27 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
EP3426780A1 (en) 2016-03-11 2019-01-16 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
WO2017155715A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
EP3426778A1 (en) 2016-03-11 2019-01-16 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
US20190177391A1 (en) 2016-03-31 2019-06-13 Baylor Research Institute Angiopoietin-like protein 8 (angptl8)
RU2018137045A (ru) 2016-04-14 2020-05-14 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидные полипептиды, обладающие улучшенным спектром активности, и пути их применения
EP3445861B1 (en) 2016-04-19 2021-12-08 Pioneer Hi-Bred International, Inc. Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof
CA3018384A1 (en) 2016-05-04 2017-11-09 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
MA45030A (fr) 2016-05-20 2019-03-27 Basf Agro Bv Peptides à double transit pour le ciblage de polypeptides
WO2017216704A1 (en) 2016-06-13 2017-12-21 Benson Hill Biosystems, Inc. Increasing plant growth and yield by using a phenylalanine ammonia lyase sequence
MX2018014993A (es) 2016-06-14 2019-09-06 Pioneer Hi Bred Int Uso de endonucleasa cpf1 para modificaciones de genoma de planta.
CA3022858A1 (en) 2016-06-16 2017-12-21 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
WO2017216384A1 (en) 2016-06-17 2017-12-21 Evaxion Biotech Aps Vaccination targeting ichthyophthirius multifiliis
WO2017222773A1 (en) 2016-06-20 2017-12-28 Pioneer Hi-Bred International, Inc. Novel cas systems and methods of use
CA3028946A1 (en) 2016-06-22 2017-12-28 Benson Hill Biosystems, Inc. Increasing plant growth and yield by using an adp-glucose pyrophosphorylase sequence
WO2017221115A1 (en) 2016-06-23 2017-12-28 Benson Hill Biosystems, Inc. Increasing plant growth and yield by using a psan sequence
WO2017220787A1 (en) 2016-06-24 2017-12-28 Evaxion Biotech Aps Vaccines against aearomonas salmonicida infection
UA127388C2 (uk) 2016-06-24 2023-08-09 Піонір Хай-Бред Інтернешнл, Інк. Регуляторний елемент рослини і спосіб його застосування
US11371053B2 (en) 2016-06-29 2022-06-28 Benson Hill, Inc. Increasing plant growth and yield by expression of an m-type thioredoxin
AU2017290805B2 (en) 2016-07-01 2023-11-16 Research Development Foundation Elimination of proliferating cells from stem cell-derived grafts
EP3478052B1 (en) 2016-07-01 2021-08-25 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
WO2018013333A1 (en) 2016-07-12 2018-01-18 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
AU2017294685B2 (en) 2016-07-15 2023-10-26 Basf Se Plants having increased tolerance to herbicides
EP3487872A1 (en) 2016-07-22 2019-05-29 Evaxion Biotech ApS Chimeric proteins for inducing immunity towards infection with s. aureus
CA3032014A1 (en) 2016-07-27 2018-02-01 BASF Agro B.V. Plants having increased tolerance to herbicides
WO2018035429A1 (en) 2016-08-18 2018-02-22 Wisconsin Alumni Research Foundation Peptides that inhibit syndecan-1 activation of vla-4 and igf-1r
AU2017319702B2 (en) 2016-09-02 2024-11-14 The Regents Of The University Of California Methods and compositions involving interleukin-6 receptor alpha-binding single chain variable fragments
JP7248571B2 (ja) 2016-10-05 2023-03-29 フジフィルム セルラー ダイナミクス，インコーポレイテッド ＭｅＣＰ２が破壊された誘導多能性幹細胞からの成熟系列の生成
AU2017340644B2 (en) 2016-10-05 2024-05-09 FUJIFILM Cellular Dynamics, Inc. Methods for directed differentiation of pluripotent stem cells to HLA homozygous immune cells
CA3042193A1 (en) 2016-10-31 2018-05-11 Benson Hill Biosystems, Inc. Increasing plant growth and yield by using an erf transcription factor sequence
EP3535285B1 (en) 2016-11-01 2022-04-06 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
KR20190112263A (ko) 2016-12-12 2019-10-04 멀티비르 인코포레이티드 암 및 감염성 질환의 치료 및 예방을 위한 바이러스 유전자 치료요법 및 면역 체크포인트 억제제를 포함하는 방법 및 조성물
BR112019012339A2 (pt) 2016-12-14 2019-11-26 Pioneer Hi Bred Int polipeptídeo inseticida recombinante, composição, construto de dna, célula hospedeira, planta transgênica, método para inibir o crescimento ou extermínio de uma praga de inseto ou população de praga, polipeptídeo ipd093 quimérico e proteína de fusão
CN110462047B (zh) 2016-12-16 2024-12-27 双刃基金会 晚疫病抗性基因及使用方法
US11879132B2 (en) 2016-12-20 2024-01-23 BASF Agro B.V. Plants having increased tolerance to herbicides
US11213028B2 (en) 2016-12-22 2022-01-04 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2018127545A1 (en) 2017-01-05 2018-07-12 Evaxion Biotech Aps Vaccines targeting pseudomonas aeruginosa
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
WO2018148001A1 (en) 2017-02-08 2018-08-16 Pioneer Hi-Bred International Inc Insecticidal combinations of plant derived insecticidal proteins and methods for their use
EP3585149A4 (en) 2017-02-22 2020-10-28 Yield10 Bioscience, Inc. TRANSGENIC SOIL PLANTS WITH IMPROVED MITOCHONDRIAL TRANSPORTER PROTEIN CONTENTS
SG11201909331UA (en) 2017-04-18 2019-11-28 Fujifilm Cellular Dynamics Inc Antigen-specific immune effector cells
US20200407737A1 (en) 2017-05-03 2020-12-31 KWS SAAT SE & Co. KGaA Use of crispr-cas endonucleases for plant genome engineering
RU2019140646A (ru) 2017-05-11 2021-06-11 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидные белки и способы их применения
WO2018209209A1 (en) 2017-05-12 2018-11-15 Two Blades Foundation Methods for screening proteins for pattern recognition receptor function in plant protoplasts
WO2018213679A1 (en) 2017-05-19 2018-11-22 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
BR112019024479A2 (pt) 2017-05-22 2020-07-14 Benson Hill, Inc. aumento do crescimento e rendimento de plantas usando uma sequência de transportador abc
CN110914438A (zh) 2017-05-26 2020-03-24 先锋国际良种公司 具有改善的活性谱的杀昆虫多肽及其用途
BR112020000690A2 (pt) 2017-07-13 2020-07-14 Benson Hill, Inc. aumento do crescimento e rendimento de plantas pelo uso de uma ferredoxina-tiorredoxina redutase
CN111542608A (zh) 2017-07-28 2020-08-14 双刃基金会 马铃薯y病毒抗性基因及使用方法
EP3665279B1 (en) 2017-08-09 2023-07-19 Benson Hill, Inc. Compositions and methods for modifying genomes
US11359207B2 (en) 2017-08-17 2022-06-14 Benson Hill, Inc. Increasing plant growth and yield by using a glutaredoxin
LT3675623T (lt) 2017-08-29 2025-09-10 KWS SAAT SE & Co. KGaA Patobulintas mėlynasis aleuronas ir kitos segregacijos sistemos
US11649465B2 (en) 2017-09-11 2023-05-16 R.J. Reynolds Tobacco Company Methods and compositions for increasing expression of genes of interest in a plant by co-expression with p21
CN111373046A (zh) 2017-09-25 2020-07-03 先锋国际良种公司 组织偏好性启动子和使用方法
CN111465321B (zh) 2017-10-13 2022-12-06 先锋国际良种公司 用于植物细胞的细胞重编程的系统和方法
US20200165626A1 (en) 2017-10-13 2020-05-28 Pioneer Hi-Bred International, Inc. Virus-induced gene silencing technology for insect control in maize
CN111566212A (zh) 2017-11-03 2020-08-21 因特尔纳技术有限公司 miRNA分子，等同物，安塔够妙或其来源用于治疗和/或诊断与神经元缺陷相关的病症和/或疾病或用于神经元生成和/或再生
WO2019099493A1 (en) 2017-11-14 2019-05-23 Henry Ford Health System Compositions for use in the treatment and prevention of cardiovascular disorders resulting from cerebrovascular injury
CA3083071A1 (en) 2017-11-21 2019-05-31 Benson Hill, Inc. Increasing plant growth and yield by using a quinone oxidoreductase
WO2019108619A1 (en) 2017-11-28 2019-06-06 Two Blades Foundation Methods and compositions for enhancing the disease resistance of plants
AR114807A1 (es) 2017-11-29 2020-10-21 Basf Se Plantas que tienen una mayor tolerancia a herbicidas
WO2019123246A1 (en) 2017-12-19 2019-06-27 Benson Hill Biosystems, Inc. Modified agpase large subunit sequences and methods for detection of precise genome edits
EP4122947A1 (en) 2017-12-19 2023-01-25 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides and uses thereof
WO2019136174A2 (en) 2018-01-03 2019-07-11 Uwm Research Foundation, Inc. Sterile mutant and two line breeding system
EP3735467A4 (en) 2018-01-05 2021-12-01 Ottawa Hospital Research Institute MODIFIED VACCINE VECTORS
US11732271B2 (en) 2018-01-12 2023-08-22 The Sainsbury Laboratory Stem rust resistance genes and methods of use
MX2020007682A (es) 2018-01-17 2020-09-14 Basf Se Plantas que tienen una mayor tolerancia a herbicidas.
WO2019145399A1 (en) 2018-01-24 2019-08-01 Evaxion Biotech Aps Vaccines for prophylaxis of s. aureus infections
WO2019165168A1 (en) 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
EP3759489A1 (en) 2018-03-02 2021-01-06 Pioneer Hi-Bred International, Inc. Plant health assay
US11332752B2 (en) 2018-03-12 2022-05-17 Pioneer Hi-Bred International, Inc. Use of morphogenic factors for the improvement of gene editing
CA3092078A1 (en) 2018-03-14 2019-09-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
AU2019234562B2 (en) 2018-03-14 2024-08-01 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
WO2020036635A2 (en) 2018-03-19 2020-02-20 Multivir Inc. Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer
CN111902547B (zh) 2018-03-23 2024-06-14 先锋国际良种公司 鉴定、选择和产生疾病抗性作物的方法
US11649455B2 (en) 2018-03-30 2023-05-16 University Of Geneva Micro RNA expression constructs and uses thereof
CN108642202B (zh) * 2018-04-16 2021-12-21 张家口市农业科学院 与谷子茎节数性状相关的snp标记及其检测引物和应用
CN111988988A (zh) 2018-04-18 2020-11-24 先锋国际良种公司 鉴定、选择和产生抗白叶枯病水稻的方法
US11708580B2 (en) 2018-05-09 2023-07-25 Benson Hill, Inc. Increasing plant growth and yield by using a DUF2996 domain-containing protein
WO2019226508A1 (en) 2018-05-22 2019-11-28 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
CN112351679B (zh) 2018-06-06 2023-06-13 华中农业大学 鉴定、选择和产生南方玉米锈病抗性作物的方法
US20220307047A1 (en) 2018-06-14 2022-09-29 Benson Hill, Inc. Increasing plant growth and yield by using a ring/u-box superfamily protein
CA3097915A1 (en) 2018-06-28 2020-01-02 Pioneer Hi-Bred International, Inc. Methods for selecting transformed plants
WO2020005667A1 (en) 2018-06-29 2020-01-02 Pioneer Hi-Bred International, Inc. Compositions and methods for editing an endogenous nac gene in plants
WO2020046701A1 (en) 2018-08-29 2020-03-05 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3846615A4 (en) 2018-09-04 2022-05-25 Yield10 Bioscience, Inc. GENETICALLY MODIFIED LAND PLANTS THAT EXPRESS AN INCREASED SEED YIELD PROTEIN AND/OR AN RNA FOR INCREASED SEED YIELD
WO2020069313A2 (en) 2018-09-28 2020-04-02 Henry Ford Health System Use of extracellular vesicles in combination with tissue plasminogen activator and/or thrombectomy to treat stroke
WO2020083904A1 (en) 2018-10-22 2020-04-30 Evaxion Biotech Aps Vaccines targeting m. catharrhalis
WO2020123887A2 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Novel crispr-cas systems for genome editing
WO2020157164A1 (en) 2019-01-30 2020-08-06 Enobraq Modified plant with improved rubisco activity
WO2020171889A1 (en) 2019-02-19 2020-08-27 University Of Rochester Blocking lipid accumulation or inflammation in thyroid eye disease
WO2020174044A1 (en) 2019-02-27 2020-09-03 Evaxion Biotech Aps Vaccines targeting h. influenzae
JP2022524615A (ja) 2019-03-11 2022-05-09 パイオニア ハイ－ブレッド インターナショナル， インコーポレイテッド クローン植物の作製方法
EP3947425A1 (en) 2019-03-27 2022-02-09 Pioneer Hi-Bred International, Inc. Plant explant transformation
EP3947696A1 (en) 2019-03-28 2022-02-09 Pioneer Hi-Bred International, Inc. Modified agrobacterium strains and use thereof for plant transformation
BR112021020770A2 (pt) 2019-04-18 2022-01-04 Pioneer Hi Bred Int Fatores de embriogênese para reprogramação celular de uma célula vegetal
US12116583B2 (en) 2019-05-14 2024-10-15 Yield10 Bioscience, Inc. Modified plants comprising a polynucleotide comprising a non-cognate promoter operably linked to a coding sequence that encodes a transcription factor
US12514914B2 (en) 2019-05-14 2026-01-06 The University Of Chicago Methods and compositions comprising Staphylococcus protein a (SpA) variants
AR122276A1 (es) 2019-06-27 2022-08-31 Two Blades Found Receptores de reconocimiento del patrón atrlp23 manipulados por ingeniería y métodos de uso
US20210071193A1 (en) 2019-07-12 2021-03-11 The Regents Of The University Of California Plants with enhanced resistance to bacterial pathogens
CN120484131A (zh) 2019-07-19 2025-08-15 费城儿童医院 包含磷脂酰肌醇蛋白聚糖2结合结构域的嵌合抗原受体
US12371706B2 (en) 2019-08-23 2025-07-29 Pioneer Hi-Bred International, Inc. Methods of identifying, selecting, and producing anthracnose stalk rot resistant crops
MX2022002642A (es) 2019-09-05 2022-06-14 Benson Hill Inc Composiciones y metodos para modificar genomas.
WO2021076930A1 (en) 2019-10-18 2021-04-22 The Regents Of The University Of California Plxdc activators and their use in the treatment of blood vessel disorders
US12604825B2 (en) 2019-11-01 2026-04-21 Purecircle Usa Inc. Stevia cultivar ‘18136109’
WO2021113644A1 (en) 2019-12-05 2021-06-10 Multivir Inc. Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
US20230050225A1 (en) 2020-01-06 2023-02-16 Evaxion Biotech A/S Vaccines targeting Neisseria gonorrhoeae
CN111153974A (zh) 2020-01-15 2020-05-15 华中农业大学 玉米抗病基因和分子标记及其应用
US20230056396A1 (en) * 2020-01-17 2023-02-23 Asklepios Biopharmaceutical, Inc. Systems and methods for synthetic regulatory sequence design or production
US20230091338A1 (en) 2020-02-24 2023-03-23 Pioneer Hi-Bred International, Inc. Intra-genomic homologous recombination
BR112022020714A2 (pt) 2020-04-15 2022-12-20 Pioneer Hi Bred Int Identificação de gene efetor de patógeno vegetal e de resistência à doença, composições e métodos de uso
CN115715295A (zh) 2020-05-27 2023-02-24 安逊生物科学股份有限公司 将car t细胞重新定向到感兴趣的抗原的衔接分子
US20230201267A1 (en) 2020-05-29 2023-06-29 FUJIFILM Cellular Dynamics, Inc. Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof
BR112022024064A2 (pt) 2020-05-29 2023-01-31 Fujifilm Cellular Dynamics Inc Bicamada de epitélio pigmentado da retina e fotorreceptores e uso dos mesmos
BR112022027035A2 (pt) 2020-07-14 2023-04-11 Pioneer Hi Bred Int Proteínas inseticidas e métodos para uso das mesmas
CA3189779A1 (en) 2020-08-10 2022-02-17 E. I. Du Pont De Nemours And Company Compositions and methods for enhancing resistance to northern leaf blight in maize
CN116096903A (zh) 2020-08-10 2023-05-09 先锋国际良种公司 植物调节元件及其使用方法
WO2022072335A2 (en) 2020-09-30 2022-04-07 Pioneer Hi-Bred International, Inc. Rapid transformation of monocot leaf explants
CN116635529A (zh) 2020-10-21 2023-08-22 先锋国际良种公司 双单倍体诱导物
CA3197681A1 (en) 2020-10-21 2022-04-28 Pioneer Hi-Bred International, Inc. Parthenogenesis factors and methods of using same
JP2023548556A (ja) 2020-11-05 2023-11-17 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム Ｅｇｆｒ抗原を標的とする操作されたｔ細胞受容体および使用方法
WO2022109289A1 (en) 2020-11-20 2022-05-27 AgBiome, Inc. Compositions and methods for incorporation of dna into the genome of an organism
EP4291216A1 (en) 2021-02-09 2023-12-20 University of Houston System Oncolytic virus for systemic delivery and enhanced anti-tumor activities
US20240122865A1 (en) 2021-02-19 2024-04-18 Pfizer Inc. Methods of Protecting RNA
TW202302853A (zh) 2021-02-26 2023-01-16 加拿大商新格諾康植物技術公司 自紅萵苣高量生產多酚之方法及其用途
CN115216554A (zh) 2021-04-16 2022-10-21 华中农业大学 植物病原体效应子和疾病抗性基因鉴定、组合物和使用方法
CN117242173A (zh) 2021-05-03 2023-12-15 安斯泰来再生医药协会 产生成熟角膜内皮细胞的方法
WO2022235869A1 (en) 2021-05-07 2022-11-10 Astellas Institute For Regenerative Medicine Methods of generating mature hepatocytes
EP4336997A1 (en) 2021-05-11 2024-03-20 Two Blades Foundation Methods for preparing a library of plant disease resistance genes for functional testing for disease resistance
KR20240011831A (ko) 2021-05-26 2024-01-26 후지필름 셀룰러 다이내믹스, 인코포레이티드 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법
JP2024526293A (ja) 2021-07-05 2024-07-17 エヴァクシオン・バイオテック・アクティエセルスカブ 淋菌を標的とするワクチン
US20250019717A1 (en) 2021-08-06 2025-01-16 Kws Vegetables B.V. Durable downy mildew resistance in spinach
AU2022340861A1 (en) 2021-09-03 2024-03-14 BASF Agricultural Solutions Seed US LLC Plants having increased tolerance to herbicides
CA3233104A1 (en) 2021-09-21 2023-03-30 Benson Hill, Inc. Compositions and methods comprising plants with reduced lipoxygenase and/or desaturase activities
CA3233676A1 (en) 2021-09-30 2023-04-06 The Sainsbury Laboratory Plant disease resistance genes against stem rust and methods of use
US20250066806A1 (en) 2021-10-21 2025-02-27 Benson Hill, Inc. Compositions and methods comprising plants with modified sugar content
WO2023084416A1 (en) 2021-11-09 2023-05-19 Benson Hill, Inc. Promoter elements for improved polynucleotide expression in plants
EP4436595A1 (en) 2021-11-22 2024-10-02 Pfizer Inc. Reducing risk of antigen mimicry in immunogenic medicaments
US20250051792A1 (en) 2021-12-15 2025-02-13 Benson Hill, Inc. Spatio-temporal promoters for polynucleotide expression in plants
EP4453199A1 (en) 2021-12-21 2024-10-30 Benson Hill, Inc. Compositions and methods for modifying genomes
EP4469079A1 (en) 2022-01-28 2024-12-04 Pfizer Inc. Coronavirus antigen variants
EP4234700A3 (en) 2022-02-25 2023-11-08 Benson Hill, Inc. Compositions and methods comprising plants with modified anthocyanin content
EP4493213A1 (en) 2022-03-16 2025-01-22 University of Houston System Persistent hsv gene delivery system
EP4499841A1 (en) 2022-03-25 2025-02-05 Pioneer Hi-Bred International, Inc. Methods of parthenogenic haploid induction and haploid chromosome doubling
AR128949A1 (es) 2022-04-01 2024-06-26 Benson Hill Inc Composiciones y métodos que comprenden plantas con tamaño de los órganos y/o composición proteica modificados
WO2023187757A1 (en) 2022-04-01 2023-10-05 Benson Hill, Inc. Compositions and methods comprising plants with modified saponin content
GB202206507D0 (en) 2022-05-04 2022-06-15 Antion Biosciences Sa Expression construct
WO2023213393A1 (en) 2022-05-04 2023-11-09 Evaxion Biotech A/S Staphylococcal protein variants and truncates
EP4536276A1 (en) 2022-06-10 2025-04-16 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof
CN119452078A (zh) 2022-06-29 2025-02-14 富士胶片控股美国公司 Ipsc来源的星形胶质细胞及其使用方法
WO2024023764A1 (en) 2022-07-27 2024-02-01 Benson Hill, Inc. Increasing gene expression for increased protein content in plants
WO2024023763A1 (en) 2022-07-27 2024-02-01 Benson Hill, Inc. Decreasing gene expression for increased protein content in plants
EP4562168A1 (en) 2022-07-28 2025-06-04 Institut Pasteur Hsc70-4 in host-induced and spray-induced gene silencing
US20240093220A1 (en) 2022-09-09 2024-03-21 Friedrich Alexander Universität Erlangen-Nürnberg Plant regulatory elements and uses thereof
AU2023398330A1 (en) 2022-12-12 2025-06-19 Basf Agricultural Solutions Us Llc Plants having increased tolerance to herbicides
WO2024127362A1 (en) 2022-12-15 2024-06-20 Benson Hill, Inc. Spatio-temporal promoters for polynucleotide expression in plants
WO2024130212A1 (en) 2022-12-16 2024-06-20 Turnstone Biologics Corp. Recombinant vaccinia virus encoding one or more natural killer cell and t lymphocyte inhibitors
WO2024186630A1 (en) 2023-03-03 2024-09-12 Henry Ford Health System Use of extracellular vesicles for the treatment of cancer
CA3231449A1 (en) 2023-03-10 2025-05-08 Benson Hill, Inc. Compositions and methods comprising plants with increased seed amino acid content
AU2024239266A1 (en) 2023-03-20 2025-09-25 Pioneer Hi-Bred International, Inc. Cas polypeptides with altered pam recognition
EP4437839A1 (en) 2023-03-28 2024-10-02 Benson Hill, Inc. Compositions and methods comprising plants with reduced raffinose family oligosaccharides and/or high protein content
WO2024201416A1 (en) 2023-03-31 2024-10-03 Benson Hill, Inc. Compositions and methods comprising plants with modified organ size and/or protein composition
GB202306619D0 (en) 2023-05-04 2023-06-21 Antion Biosciences Sa Cell
EP4728079A1 (en) 2023-06-13 2026-04-22 Confluence Genetics, LLC Plants with modified fatty acid and/or oil content
WO2025019283A1 (en) 2023-07-14 2025-01-23 Two Blades Foundation Methods of improving the thermostability of plant immune receptors
WO2025019221A1 (en) 2023-07-15 2025-01-23 Two Blades Foundation Broad-spectrum polerovirus resistance gene
US20250075226A1 (en) 2023-08-29 2025-03-06 University Of Freiburg Proteins for regulation of symbiotic infection and associated regulatory elements
WO2025050009A2 (en) 2023-09-01 2025-03-06 Children's Hospital Medical Center Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
WO2025059184A1 (en) 2023-09-12 2025-03-20 Pioneer Hi-Bred International, Inc. Methods and compositions for generating genome-edited paternal doubled haploids
WO2025153595A1 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
WO2025153657A2 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
GB202402745D0 (en) 2024-02-27 2024-04-10 Antion Biosciences Sa Cell
WO2025184759A1 (en) 2024-03-04 2025-09-12 Pioneer Hi-Bred International, Inc. Maize plants comprising resistance to gray leaf spot and compositions and methods for selecting and producing the same
WO2026003150A1 (en) 2024-06-28 2026-01-02 Basf Se Plants with mutated tubulin polypeptide having increased tolerance to herbicides
US20260085301A1 (en) 2024-09-20 2026-03-26 Confluence Genetics, Llc Compositions and methods for modifying genomes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5015580A (en) * 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
KR0154872B1 (ko) * 1987-12-21 1998-10-15 로버트 에이. 아미테이지 발아하는 식물종자의 아크로박테리움 매개된 형질전환

Also Published As

Publication number Publication date
DE69020850D1 (de) 1995-08-17
ATE124995T1 (de) 1995-07-15
EP0424047B1 (en) 1995-07-12
DK0424047T3 (da) 1995-11-20
EP0424047A1 (en) 1991-04-24
US5322783A (en) 1994-06-21
GR3017310T3 (en) 1995-12-31
DE69020850T2 (de) 1995-12-07

Similar Documents

Publication Publication Date Title
ES2077034T3 (es) Metodo de cultivo de tejidos para la transformacion de celulas vegetales.
FR2605185B1 (fr) Procede de culture des plantes
IL74866A (en) Method for selectively combating weeds in cultures of useful plants
SE8800157D0 (sv) Transformation and foreign gene expression in brassica species
NZ232834A (en) Reproducing coniferous plants by somatic embrogenesis using plant tissue culturing techniques
PT87394A (pt) Process for plant tissue transformation
DE69637656D1 (de) Methoden zur Züchtung von Tierzellen
ES534041A0 (es) Substrato de cultivo para las celulas, tejidos, organos vegetales y plantas enteras
NO170595C (no) Fremgangsmaate for fremstilling av biologisk aktiv human vevtypeplasminogenaktivator
BR8806136A (pt) Metodo para regeneracao de uma planta algodoeira a partir de celulas somaticas
ES8402693A1 (es) Un metodo de cultivar hidroponicamente una planta.
FI885436A7 (fi) Fermenttori soluviljelmien viljelemiseksi
ATE15693T1 (de) Zellkultur-verfahren.
DE3666458D1 (en) Method and device for the _i(in vitro) culture of plant cells and organs, as well as for the micropropagation and regeneration of complete plants
NO912621L (no) Fremgangsmaate for innfoering av dna i animalske celler.
FR2619671B1 (fr) Procede de multiplication et de culture de plantes de la famille des bromeliacees, et plantes ainsi obtenues
FI881491A7 (fi) Menetelmä sekundäärisen aineenvaihduntatuotannon aikaansaamiseksi kasv iviljelmissä.
BR8403851A (pt) Processo para obtencao e multiplicacao de genomas de virus e seus derivados,celulas ou tecidos vegetais regenerados,plantas regeneradas e emprego
FR2614498B1 (fr) Procede de culture de champignons, sur compost supplemente par un apport proteique et un apport enzymatique
DE2966082D1 (en) Process for growing human epidermal cells in tissue culture
AU584774B2 (en) Process for regenerating corn
DK587888A (da) Fremgangsmaade til dyrkning af plantevaev
IL67506A0 (en) Process for improving the efficiency of the in vitro tissue cultivating propagation of cultivated plants
DK576286A (da) Fremgangsmaade til halvkontinuerlig metabolitproduktion ved hjaelp af planteceller, dyrket in vitro
JPS5491437A (en) Pasteurizing method for culture solution in solution cultivation

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 424047

Country of ref document: ES