ES2139733T3 - Dispositivo de inhalacion. - Google Patents
Dispositivo de inhalacion.Info
- Publication number
- ES2139733T3 ES2139733T3 ES94907642T ES94907642T ES2139733T3 ES 2139733 T3 ES2139733 T3 ES 2139733T3 ES 94907642 T ES94907642 T ES 94907642T ES 94907642 T ES94907642 T ES 94907642T ES 2139733 T3 ES2139733 T3 ES 2139733T3
- Authority
- ES
- Spain
- Prior art keywords
- chamber
- turbulence
- capsule
- air
- mouthpiece
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manipulator (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Weting (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Catching Or Destruction (AREA)
Abstract
DISPOSITIVO PARA LA ADMINISTRACION DE UN MEDICAMENTO DE INHALACION EN POLVO CONTENIDO INICIALMENTE EN UNA CAPSULA QUE TIENE AL MENOS UNA APERTURA FORMADA EN LA MISMA, QUE INCLUYE UNA CAMARA DE TURBULENCIA (1) ADAPTADA PARA RECIBIR LA CAPSULA DE MEDICACION; UNA PIEZA BUCAL (2) QUE SE COMUNICA CON LA CAMARA DE TURBULENCIA (1) Y SE SEPARA DE ELLA MEDIANTE UNA REJILLA (4); AL MENOS UNA ENTRADA DE AIRE (5) EN COMUNICACION TANGENCIAL CON LA CAMARA DE TURBULENCIA (1)DE FORMA QUE EL AIRE PUEDE DESPERDIGARSE A TRAVES DEL DISPOSITIVO MEDIANTE LA PIEZA BUCAL (2) PARA DAR LUGAR A UNA CIRCULACION DE AIRE EN MOVIMIENTO A TRAVES DE LA CAMARA DE TURBULENCIA (1); Y UN ELEMENTO DE COBERTURA (7) QUE TIENE CONTINUA UNA SUPERFICIE INTERIOR BASICAMENTE PLANA, INCLUIDA EN LA BASE DE LA CAMARA DE TURBULENCIA (1) LEJOS DE LA PIEZA DENTAL (2); DICHA COBERTURA (7) ES MOVIBLE ENTRE UNA PRIMERA POSICION EN LA QUE LA CAPSULA PUEDE INSERTARSE DENTRO DE LA CAMARA DE TURBULENCIA (1) Y UNA SEGUNDA POSICION EN LA QUE LA CAPSULA ES MANTENIDA EN LA CAMARA DE TURBULENCIA (1) Y GIRA CON EL AIRE EN MOVIMIENTO A TRAVES DEL DISPOSITIVO, CON LO QUE SE DISPENSA EL MEDICAMENTO CONTENIDO EN ELLA.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939304011A GB9304011D0 (en) | 1993-02-27 | 1993-02-27 | Inhalation device |
| GB939311646A GB9311646D0 (en) | 1993-06-05 | 1993-06-05 | Inhalation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2139733T3 true ES2139733T3 (es) | 2000-02-16 |
Family
ID=26302515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94907642T Expired - Lifetime ES2139733T3 (es) | 1993-02-27 | 1994-02-28 | Dispositivo de inhalacion. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5787881A (es) |
| EP (1) | EP0773807B1 (es) |
| JP (1) | JPH08507704A (es) |
| KR (1) | KR100297344B1 (es) |
| AT (1) | ATE185977T1 (es) |
| AU (1) | AU680874B2 (es) |
| BR (1) | BR9406253A (es) |
| CA (1) | CA2157043A1 (es) |
| DE (1) | DE69421415T2 (es) |
| DK (1) | DK0773807T3 (es) |
| ES (1) | ES2139733T3 (es) |
| FI (1) | FI953983A7 (es) |
| GR (1) | GR3031814T3 (es) |
| HU (1) | HU217896B (es) |
| IL (1) | IL108780A (es) |
| NO (1) | NO311497B1 (es) |
| NZ (1) | NZ261892A (es) |
| PL (1) | PL173041B1 (es) |
| WO (1) | WO1994019041A1 (es) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9302550D0 (sv) * | 1993-07-30 | 1993-07-30 | Ernst Hoerlin | Powder inhaler |
| JP3317823B2 (ja) * | 1995-08-11 | 2002-08-26 | 株式会社ユニシアジェックス | 投薬器 |
| JP3328132B2 (ja) * | 1996-03-21 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9626233D0 (en) * | 1996-12-18 | 1997-02-05 | Chawla Brinda P S | Medicament packaging and deliveery device |
| US6062213A (en) * | 1998-06-16 | 2000-05-16 | Fuisz Technologies Ltd. | Single unit dose inhalation therapy device |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| WO2002013897A2 (en) | 2000-08-14 | 2002-02-21 | Advanced Inhalation Research, Inc. | Inhalation device and method |
| US6357490B1 (en) * | 2000-08-22 | 2002-03-19 | Advanced Inhalation Research, Inc. | System, method and apparatus for filling containers |
| SE0100034D0 (sv) * | 2001-01-04 | 2001-01-04 | Astrazeneca Ab | A delivery device |
| US6443152B1 (en) * | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| US6722364B2 (en) * | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| ATE255929T1 (de) * | 2001-03-05 | 2003-12-15 | Ivo Pera | Inhalationsvorrichtung zum dispergieren von in kapseln enthaltenen pulverförmigen medikamente durch den respirationstrakt |
| US6766799B2 (en) * | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| CA2444729A1 (en) * | 2001-05-10 | 2002-11-14 | Vectura Delivery Devices Limited | Inhalers |
| GB2375308A (en) * | 2001-05-10 | 2002-11-13 | Cambridge Consultants | Inhalers |
| US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
| GB0130055D0 (en) | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
| WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
| US7562769B2 (en) | 2003-03-15 | 2009-07-21 | Brintech International Limited | Formulation and presentation of medicaments |
| GB0317374D0 (en) | 2003-07-24 | 2003-08-27 | Glaxo Group Ltd | Medicament dispenser |
| USD527817S1 (en) | 2004-05-13 | 2006-09-05 | Novartis Ag | Inhaler |
| GB0410712D0 (en) * | 2004-05-13 | 2004-06-16 | Novartis Ag | Organic compounds |
| GB0418278D0 (en) | 2004-08-16 | 2004-09-15 | Glaxo Group Ltd | Medicament dispenser |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| US7694676B2 (en) * | 2005-04-22 | 2010-04-13 | Boehringer Ingelheim Gmbh | Dry powder inhaler |
| GB0515584D0 (en) * | 2005-07-28 | 2005-09-07 | Glaxo Group Ltd | Medicament dispenser |
| CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
| US7987845B2 (en) * | 2006-01-31 | 2011-08-02 | Oriel Therapeutics, Inc. | Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods |
| IN2015DN00888A (es) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
| DE102006010089A1 (de) * | 2006-02-24 | 2007-10-18 | Aha-Kunststofftechnik Gmbh | Trockenpulver-Inhalator |
| GB0611656D0 (en) * | 2006-06-13 | 2006-07-19 | Cambridge Consultants | Dry powder inhalers |
| GB0616299D0 (en) * | 2006-08-16 | 2006-09-27 | Cambridge Consultants | Drug Capsules for dry power inhalers |
| GB0622827D0 (en) * | 2006-11-15 | 2006-12-27 | Glaxo Group Ltd | Sheet driver for use in a drug dispenser |
| WO2008091355A2 (en) * | 2007-01-24 | 2008-07-31 | Breathe Pharmaceuticals, Inc. | Drug transfer device |
| US8496002B2 (en) * | 2007-06-12 | 2013-07-30 | Civitas Therapeutics, Inc. | Powder inhaler devices |
| EP2534957B1 (en) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Delivering aerosolizable products |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| KR101628410B1 (ko) | 2008-06-20 | 2016-06-08 | 맨카인드 코포레이션 | 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법 |
| WO2010011329A2 (en) * | 2008-07-23 | 2010-01-28 | Map Pharmaceuticals, Inc. | The delivery of powdered drug via inhalation |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| WO2010042035A1 (en) * | 2008-10-08 | 2010-04-15 | Astrazeneca Ab | Inhaler with indexing linked to movement of cover |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| CN104721825B (zh) | 2009-06-12 | 2019-04-12 | 曼金德公司 | 具有确定比表面积的二酮哌嗪颗粒 |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| EP2498848A2 (en) | 2009-11-12 | 2012-09-19 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
| IL223742A (en) | 2010-06-21 | 2016-06-30 | Mannkind Corp | A dry powder inhaler and preparation for it |
| FR2962342B1 (fr) * | 2010-07-07 | 2013-02-15 | Valois Sas | Inhalateur de poudre seche. |
| FR2962341B1 (fr) * | 2010-07-07 | 2013-02-15 | Valois Sas | Inhalateur de poudre seche. |
| US8561609B2 (en) | 2010-12-07 | 2013-10-22 | Respira Therapeutics, Inc. | Dry powder inhaler |
| AU2012236150B2 (en) | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| US10220164B2 (en) | 2011-07-13 | 2019-03-05 | Pharmaxis Ltd. | Delivery devices |
| US10786637B2 (en) * | 2011-07-13 | 2020-09-29 | Pharmaxis Ltd. | Delivery devices |
| ES2761316T3 (es) * | 2011-07-13 | 2020-05-19 | Pharmaxis Ltd | Mejoras relacionadas con dispositivos de suministro |
| US9446209B2 (en) * | 2011-09-07 | 2016-09-20 | Concentrx Pharmaceuticals, Inc. | Dry powder inhalation device |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
| US9764103B2 (en) * | 2012-10-05 | 2017-09-19 | Lily A. Neff | Salt puffer |
| US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
| AU2014228415B2 (en) | 2013-03-15 | 2018-08-09 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| WO2016075749A1 (ja) * | 2014-11-10 | 2016-05-19 | 日本たばこ産業株式会社 | カートリッジ及び非燃焼型香味吸引器 |
| CN107427650A (zh) | 2015-01-14 | 2017-12-01 | 瑞必治公司 | 粉末分散方法和装置 |
| PT108426B (pt) * | 2015-04-30 | 2017-07-24 | Hovione Farmaciência S A | Inalador de pó para administração de doses elevadas de fármacos |
| EP3248641B1 (en) * | 2016-05-23 | 2019-10-23 | Presspart Manufacturing Ltd. | Dry powder inhaler |
| AU2018244582A1 (en) | 2017-03-28 | 2019-09-19 | Concentrx Pharmaceuticals, Inc. | Devices and methods for delivering dry powder medicaments |
| WO2018187273A1 (en) * | 2017-04-06 | 2018-10-11 | Mylan Inc. | Low-cost single use powder inhaler |
| KR101992171B1 (ko) * | 2017-06-27 | 2019-06-25 | 한국유나이티드제약 주식회사 | 건조분말 흡입기 |
| CN110201281B (zh) * | 2018-02-28 | 2021-08-06 | 张江 | 吸入给药装置和吸入给药组合结构 |
| CA193818S (en) * | 2020-03-11 | 2022-04-20 | Breathesuite Inc | Monitoring device for inhalers |
| FR3116440B1 (fr) * | 2020-11-20 | 2025-01-03 | Nemera La Verpilliere | Embout pour dispositif de distribution de produit |
| KR102662529B1 (ko) * | 2021-09-02 | 2024-04-30 | 중앙대학교 산학협력단 | 휴대용 약물 흡입기 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4069819A (en) * | 1973-04-13 | 1978-01-24 | Societa Farmaceutici S.P.A. | Inhalation device |
| IT1016489B (it) * | 1974-03-18 | 1977-05-30 | Isf Spa | Inalatore |
| AT384552B (de) * | 1985-08-01 | 1987-12-10 | Hurka Wilhelm | Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft |
| GB8804069D0 (en) * | 1988-02-22 | 1988-03-23 | Britains Petite Ltd | Dispensers for powdered medication |
| IT1228460B (it) * | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore monouso con capsula pre-forata |
| IT1237118B (it) * | 1989-10-27 | 1993-05-18 | Miat Spa | Inalatore multidose per farmaci in polvere. |
| NZ250988A (en) * | 1990-06-14 | 1995-09-26 | Rhone Poulenc Rorer Ltd | Powder inhaler: swirling chamber with anti-static walls |
| US5429122A (en) * | 1990-09-26 | 1995-07-04 | Zanen; Pieter | Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber |
| DE59107894D1 (de) * | 1991-03-21 | 1996-07-11 | Ritzau Pari Werk Gmbh Paul | Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie |
| GB9106648D0 (en) * | 1991-03-28 | 1991-05-15 | Rhone Poulenc Rorer Ltd | New inhaler |
| US5476093A (en) * | 1992-02-14 | 1995-12-19 | Huhtamaki Oy | Device for more effective pulverization of a powdered inhalation medicament |
| JP3166123B2 (ja) * | 1992-09-09 | 2001-05-14 | フアイソンズ・ピーエルシー | 薬剤パッケージング |
| US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| EP0682955B1 (de) * | 1994-05-19 | 2001-09-05 | PARI GmbH Spezialisten für effektive Inhalation | Vorrichtung zur Trocknung und Pufferung von Aerosolen |
-
1994
- 1994-02-27 IL IL10878094A patent/IL108780A/en not_active IP Right Cessation
- 1994-02-28 KR KR1019950703654A patent/KR100297344B1/ko not_active Expired - Fee Related
- 1994-02-28 HU HU9502496A patent/HU217896B/hu not_active IP Right Cessation
- 1994-02-28 DE DE69421415T patent/DE69421415T2/de not_active Expired - Fee Related
- 1994-02-28 JP JP6518782A patent/JPH08507704A/ja not_active Ceased
- 1994-02-28 DK DK94907642T patent/DK0773807T3/da active
- 1994-02-28 AU AU61136/94A patent/AU680874B2/en not_active Ceased
- 1994-02-28 CA CA002157043A patent/CA2157043A1/en not_active Abandoned
- 1994-02-28 NZ NZ261892A patent/NZ261892A/en unknown
- 1994-02-28 FI FI953983A patent/FI953983A7/fi unknown
- 1994-02-28 AT AT94907642T patent/ATE185977T1/de not_active IP Right Cessation
- 1994-02-28 PL PL94310433A patent/PL173041B1/pl unknown
- 1994-02-28 ES ES94907642T patent/ES2139733T3/es not_active Expired - Lifetime
- 1994-02-28 EP EP94907642A patent/EP0773807B1/en not_active Expired - Lifetime
- 1994-02-28 BR BR9406253A patent/BR9406253A/pt not_active IP Right Cessation
- 1994-02-28 WO PCT/GB1994/000388 patent/WO1994019041A1/en not_active Ceased
-
1995
- 1995-08-24 NO NO19953327A patent/NO311497B1/no not_active IP Right Cessation
-
1997
- 1997-02-03 US US08/789,073 patent/US5787881A/en not_active Expired - Fee Related
-
1999
- 1999-11-10 GR GR990402907T patent/GR3031814T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ261892A (en) | 1997-07-27 |
| IL108780A0 (en) | 1994-05-30 |
| AU680874B2 (en) | 1997-08-14 |
| JPH08507704A (ja) | 1996-08-20 |
| DE69421415T2 (de) | 2000-02-10 |
| NO953327L (no) | 1995-08-24 |
| GR3031814T3 (en) | 2000-02-29 |
| HUT73520A (en) | 1996-08-28 |
| CA2157043A1 (en) | 1994-09-01 |
| HU9502496D0 (en) | 1995-10-30 |
| PL310433A1 (en) | 1995-12-11 |
| DE69421415D1 (de) | 1999-12-02 |
| HU217896B (hu) | 2000-05-28 |
| KR100297344B1 (ko) | 2001-10-24 |
| IL108780A (en) | 1999-06-20 |
| ATE185977T1 (de) | 1999-11-15 |
| AU6113694A (en) | 1994-09-14 |
| PL173041B1 (pl) | 1998-01-30 |
| DK0773807T3 (da) | 2000-04-17 |
| EP0773807B1 (en) | 1999-10-27 |
| EP0773807A1 (en) | 1997-05-21 |
| BR9406253A (pt) | 1996-02-13 |
| FI953983A0 (fi) | 1995-08-24 |
| NO953327D0 (no) | 1995-08-24 |
| FI953983A7 (fi) | 1995-08-24 |
| NO311497B1 (no) | 2001-12-03 |
| US5787881A (en) | 1998-08-04 |
| WO1994019041A1 (en) | 1994-09-01 |
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