ES2077124T3 - Empleo de lactonas de 10 atomos en el anillo como reguladores de lipidos. - Google Patents

Empleo de lactonas de 10 atomos en el anillo como reguladores de lipidos.

Info

Publication number: ES2077124T3
Authority: ES; Spain
Prior art keywords: elevated; lactones; atoms; ring; hydroxyl
Prior art date: 1990-08-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES91114331T

Other languages

English (en)

Spanish (es)

Inventor

Ernold Dr Dr Granzer

Peter Dr Hammann

Joachim Dr Wink

Susanne Dr Grabley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-28

Filing date

1991-08-27

Publication date

1995-11-16

1991-08-27 Application filed by Hoechst AG filed Critical Hoechst AG

1995-11-16 Application granted granted Critical

1995-11-16 Publication of ES2077124T3 publication Critical patent/ES2077124T3/es

2011-08-27 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

150000002596 lactones Chemical class 0.000 title 1
150000002632 lipids Chemical class 0.000 title 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
230000000055 hyoplipidemic effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES91114331T 1990-08-28 1991-08-27 Empleo de lactonas de 10 atomos en el anillo como reguladores de lipidos. Expired - Lifetime ES2077124T3 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4027100		1990-08-28

Publications (1)

Publication Number	Publication Date
ES2077124T3 true ES2077124T3 (es)	1995-11-16

Family

ID=6413028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES91114331T Expired - Lifetime ES2077124T3 (es)	1990-08-28	1991-08-27	Empleo de lactonas de 10 atomos en el anillo como reguladores de lipidos.

Country Status (9)

Country	Link
US (1)	US5200424A (da)
EP (1)	EP0477552B1 (da)
JP (1)	JPH04230628A (da)
DE (1)	DE59106261D1 (da)
DK (1)	DK0477552T3 (da)
ES (1)	ES2077124T3 (da)
GR (1)	GR3017592T3 (da)
IE (1)	IE913017A1 (da)
PT (1)	PT98785A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5753262A (en) *	1995-06-07	1998-05-19	Aronex Pharmaceuticals, Inc.	Cationic lipid acid salt of 3beta N- (N', N'-dimethylaminoethane) - carbamoyl!cholestrol and halogenated solvent-free preliposomal lyophilate thereof
US20010006644A1 (en)	1997-07-31	2001-07-05	David J. Bova	Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
US6103733A (en) *	1998-09-09	2000-08-15	Bachmann; Kenneth A.	Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
US20090069275A1 (en) *	2006-02-17	2009-03-12	Rocca Jose G	Low flush niacin formulation
KR20100015343A (ko) *	2007-03-01	2010-02-12	컨커스 헬스 사이언스 엘엘씨	이노시톨 니아시네이트의 이성질체 및 그 용도
KR100836960B1 (ko)	2007-09-07	2008-06-10	주식회사 서울제약	새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE58908507D1 (de) *	1988-03-15	1994-11-24	Hoechst Ag	Neue 10-Ring-Lactone, Verfahren zu ihrer Herstellung und ihre Verwendung.

1991
- 1991-08-26 US US07/749,869 patent/US5200424A/en not_active Expired - Fee Related
- 1991-08-27 DK DK91114331.1T patent/DK0477552T3/da active
- 1991-08-27 JP JP3215284A patent/JPH04230628A/ja active Pending
- 1991-08-27 EP EP91114331A patent/EP0477552B1/de not_active Expired - Lifetime
- 1991-08-27 ES ES91114331T patent/ES2077124T3/es not_active Expired - Lifetime
- 1991-08-27 DE DE59106261T patent/DE59106261D1/de not_active Expired - Fee Related
- 1991-08-27 IE IE301791A patent/IE913017A1/en unknown
- 1991-08-27 PT PT98785A patent/PT98785A/pt not_active Application Discontinuation
1995
- 1995-09-29 GR GR950402705T patent/GR3017592T3/el unknown

Also Published As

Publication number	Publication date
EP0477552B1 (de)	1995-08-16
JPH04230628A (ja)	1992-08-19
DK0477552T3 (da)	1995-12-18
GR3017592T3 (en)	1995-12-31
EP0477552A1 (de)	1992-04-01
PT98785A (pt)	1992-07-31
US5200424A (en)	1993-04-06
DE59106261D1 (de)	1995-09-21
IE913017A1 (en)	1992-03-11

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Legal Events

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Description

1995-11-16

FG2A

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