ES2078256T3 - Formula farmaceutica para uso topico que contiene diclofenaco sodico. - Google Patents
Formula farmaceutica para uso topico que contiene diclofenaco sodico.Info
- Publication number
- ES2078256T3 ES2078256T3 ES90106549T ES90106549T ES2078256T3 ES 2078256 T3 ES2078256 T3 ES 2078256T3 ES 90106549 T ES90106549 T ES 90106549T ES 90106549 T ES90106549 T ES 90106549T ES 2078256 T3 ES2078256 T3 ES 2078256T3
- Authority
- ES
- Spain
- Prior art keywords
- diclofenaco
- containing sodium
- topical use
- use containing
- pharmaceutical formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 229960001193 diclofenac sodium Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE DESCRIBE UN COMPUESTO FARMACEUTICO CON DICLOFENAC-SODIO PARA APLICACION TOPICA EN FORMA DE GEL. EL FORMADOR DEL GEL ES UN DERIVADO DE LA CELULOSA, EN ESPECIAL HIDROXIPROPILMETILCELULOSA. EL GEL SE PRESTA COMO MEDICAMENTO ANTIRREUMATICO, ANTIFLOGISTICO Y/O ANTIINFLAMATORIO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP90106549A EP0450123B1 (de) | 1990-04-05 | 1990-04-05 | Diclofenac-Natrium enthaltende pharmazeutische Zusammensetzung zur topischen Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2078256T3 true ES2078256T3 (es) | 1995-12-16 |
Family
ID=8203859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90106549T Expired - Lifetime ES2078256T3 (es) | 1990-04-05 | 1990-04-05 | Formula farmaceutica para uso topico que contiene diclofenaco sodico. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0450123B1 (es) |
| JP (1) | JPH03291222A (es) |
| AT (1) | ATE124627T1 (es) |
| DE (1) | DE59009378D1 (es) |
| DK (1) | DK0450123T3 (es) |
| ES (1) | ES2078256T3 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2523428B2 (ja) * | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
| US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| FR2808685B1 (fr) * | 2000-05-12 | 2004-10-08 | Sanofi Synthelabo | Compositions pharmaceutiques pour administration transdermique d'agents anti-inflammatoires |
| WO2006134406A1 (en) * | 2005-06-14 | 2006-12-21 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable pharmaceutical gel of diclofenac sodium |
| US8247507B2 (en) | 2006-09-21 | 2012-08-21 | Basf Se | Cationic polymers as thickeners for aqueous and alcoholic compositions |
| RU2463038C2 (ru) | 2006-10-17 | 2012-10-10 | Нуво Рисерч Инк. | Диклофенаковый гель |
| US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| US8546450B1 (en) | 2009-03-31 | 2013-10-01 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7776275A (en) * | 1974-04-11 | 1976-08-05 | Warner Lambert Co | Production of base for topical steroids |
| JPS5381616A (en) * | 1976-12-27 | 1978-07-19 | Kowa Co | Production of antiinflammatory and anodyne ointment |
| LU85145A1 (fr) * | 1983-12-19 | 1985-09-12 | Midit | Composition pharmaceutique contenant de l'acide p-butoxyphenylacethydroxamique,procede de preparation de cette composition et methode d'utilisation de celle-ci |
| DE3400106A1 (de) * | 1984-01-04 | 1985-07-11 | Klaus-Dieter Dr. 3550 Marburg Bremecker | Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung |
| DE3446873A1 (de) * | 1984-12-21 | 1986-07-10 | Merckle Gmbh | Fluessige diclofenac-zubereitungen |
| DE3522550A1 (de) * | 1985-06-24 | 1987-01-02 | Klinge Co Chem Pharm Fab | Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung |
| JPS62181226A (ja) * | 1986-02-05 | 1987-08-08 | Ikeda Mohandou:Kk | 消炎鎮痛外用剤 |
| JPH06104624B2 (ja) * | 1986-05-07 | 1994-12-21 | 太郎 小木曽 | 経皮吸収剤 |
| JPS63222121A (ja) * | 1987-03-10 | 1988-09-16 | Nippon Soda Co Ltd | 徐放性ゲル製剤 |
| JPH0696527B2 (ja) * | 1987-05-20 | 1994-11-30 | 佐藤製薬株式会社 | 消炎鎮痛ゲル剤 |
-
1990
- 1990-04-05 ES ES90106549T patent/ES2078256T3/es not_active Expired - Lifetime
- 1990-04-05 DE DE59009378T patent/DE59009378D1/de not_active Expired - Fee Related
- 1990-04-05 DK DK90106549.0T patent/DK0450123T3/da active
- 1990-04-05 EP EP90106549A patent/EP0450123B1/de not_active Expired - Lifetime
- 1990-04-05 AT AT90106549T patent/ATE124627T1/de not_active IP Right Cessation
- 1990-06-14 JP JP2156631A patent/JPH03291222A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK0450123T3 (da) | 1995-08-21 |
| JPH03291222A (ja) | 1991-12-20 |
| EP0450123B1 (de) | 1995-07-05 |
| ATE124627T1 (de) | 1995-07-15 |
| DE59009378D1 (de) | 1995-08-10 |
| EP0450123A1 (de) | 1991-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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