ES2079389T3 - Dispersiones de polimeros liofilizados y su uso para preparar composiciones farmaceuticas de liberacion retardada. - Google Patents
Dispersiones de polimeros liofilizados y su uso para preparar composiciones farmaceuticas de liberacion retardada.Info
- Publication number
- ES2079389T3 ES2079389T3 ES90105437T ES90105437T ES2079389T3 ES 2079389 T3 ES2079389 T3 ES 2079389T3 ES 90105437 T ES90105437 T ES 90105437T ES 90105437 T ES90105437 T ES 90105437T ES 2079389 T3 ES2079389 T3 ES 2079389T3
- Authority
- ES
- Spain
- Prior art keywords
- polymer dispersions
- pharmaceutical compositions
- lyophilized polymer
- prepare delayed
- delayed pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920000642 polymer Polymers 0.000 title abstract 5
- 239000006185 dispersion Substances 0.000 title abstract 3
- 230000003111 delayed effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000013583 drug formulation Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005550 wet granulation Methods 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LATICES POLIMERICOS LIOFILIZADOS, QUE PUEDEN RECONSTITUIRSE EN AGUA PARA CONSEGUIR DISPERSIONES POLIMERICAS ACUOSAS CON UN ALTO CONTENIDO SOLIDO DE POLIMEROS. LAS DISPERSIONES POLIMERICAS RECONSTITUIDAS RESULTAN DE GRAN UTILIDAD EN LA PREPARACION DE FORMULACIONES FARMACEUTICAS DE DISTRIBUCION SOSTENIDA, EN PARTICULAR, DE FARMACOS SOLUBLES EN AGUA, MEDIANTE EL METODO DE GRANULACION HUMEDA SIN EXCESO DE HUMEDAD.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32793489A | 1989-03-23 | 1989-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2079389T3 true ES2079389T3 (es) | 1996-01-16 |
Family
ID=23278720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90105437T Expired - Lifetime ES2079389T3 (es) | 1989-03-23 | 1990-03-22 | Dispersiones de polimeros liofilizados y su uso para preparar composiciones farmaceuticas de liberacion retardada. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5326572A (es) |
| EP (1) | EP0388954B1 (es) |
| AT (1) | ATE130511T1 (es) |
| CA (1) | CA2012853A1 (es) |
| DE (1) | DE69023682T2 (es) |
| DK (1) | DK0388954T3 (es) |
| ES (1) | ES2079389T3 (es) |
| GR (1) | GR3018970T3 (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| SE9203594D0 (sv) * | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
| DE4244466C2 (de) * | 1992-12-24 | 1995-02-23 | Pharmatech Gmbh | Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten |
| US7740881B1 (en) | 1993-07-01 | 2010-06-22 | Purdue Pharma Lp | Method of treating humans with opioid formulations having extended controlled release |
| IL110014A (en) | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
| DE4324474A1 (de) * | 1993-07-21 | 1995-01-26 | Henkel Kgaa | Verwendung ausgewählter Polyvinylacetat-Dispersionen für die Oberflächenverfestigung von Sand und/oder Erdreich |
| US5879705A (en) * | 1993-07-27 | 1999-03-09 | Euro-Celtique S.A. | Sustained release compositions of morphine and a method of preparing pharmaceutical compositions |
| DE4413350A1 (de) * | 1994-04-18 | 1995-10-19 | Basf Ag | Retard-Matrixpellets und Verfahren zu ihrer Herstellung |
| DE4423078B4 (de) * | 1994-07-01 | 2005-01-13 | Awd.Pharma Gmbh & Co. Kg | Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung |
| US5684121A (en) * | 1994-12-06 | 1997-11-04 | Isp Investments Inc. | N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution |
| JP3893439B2 (ja) * | 1994-12-19 | 2007-03-14 | 第一製薬株式会社 | 徐放性粒状製剤およびその製造方法 |
| US5985313A (en) * | 1997-10-22 | 1999-11-16 | New York Blood Center, Inc. | Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients |
| US6165493A (en) * | 1997-10-22 | 2000-12-26 | New York Blood Center, Inc. | "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections" |
| US6806294B2 (en) | 1998-10-15 | 2004-10-19 | Euro-Celtique S.A. | Opioid analgesic |
| US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| ATE526950T1 (de) | 1999-10-29 | 2011-10-15 | Euro Celtique Sa | Hydrocodon-formulierungen mit gesteuerter freisetzung |
| EP2283829A1 (en) | 2000-10-30 | 2011-02-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
| UA81224C2 (uk) | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
| US20040115266A1 (en) * | 2002-02-01 | 2004-06-17 | Namburi Ranga Raju | Oral itraconazole formulations and methods of making the same |
| US20040265378A1 (en) * | 2003-06-25 | 2004-12-30 | Yingxu Peng | Method and compositions for producing granules containing high concentrations of biologically active substances |
| WO2007092718A2 (en) * | 2006-02-07 | 2007-08-16 | Fmc Corporation | Coating process to produce controlled release coatings |
| US20070281016A1 (en) * | 2006-06-06 | 2007-12-06 | Endo Pharmaceuticals Inc., A Delaware Corporation | Sustained release oxycodone composition with acrylic polymer and surfactant |
| US20080075768A1 (en) * | 2006-07-21 | 2008-03-27 | Vaughn Jason M | Hydrophobic opioid abuse deterrent delivery system using opioid antagonists |
| US9555167B2 (en) * | 2006-12-11 | 2017-01-31 | 3M Innovative Properties Company | Biocompatible antimicrobial compositions |
| US20080200890A1 (en) * | 2006-12-11 | 2008-08-21 | 3M Innovative Properties Company | Antimicrobial disposable absorbent articles |
| US11084908B1 (en) | 2018-08-31 | 2021-08-10 | Evonik Operations Gmbh | Process for preparing a polymer powder |
| CN114456404B (zh) * | 2022-01-24 | 2024-02-13 | 哈尔滨工业大学 | 一种液态金属柔性可穿戴器件及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2800463A (en) * | 1953-05-14 | 1957-07-23 | Shawinigan Resins Corp | Polyvinyl acetate powder and process of making the same |
| US2809192A (en) * | 1954-05-25 | 1957-10-08 | Atlantic Res Corp | Method of making cellulose esters in the form of small, dense, spherical particles |
| US3942261A (en) * | 1973-12-21 | 1976-03-09 | Toyo Ink Manufacturing Co., Ltd. | Method for producing powder paint |
| US4330338A (en) * | 1978-10-02 | 1982-05-18 | Purdue Research Foundation | Pharmaceutical coating composition, and preparation and dosages so coated |
| AU569277B2 (en) * | 1983-03-03 | 1988-01-28 | Dow Chemical Company, The | Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents |
| US4652442A (en) * | 1983-07-05 | 1987-03-24 | Arcana Chem. Pharm. Fabrik Gesellschaft M.B.H. | Process of producing a sustained release preparation containing indomethacin or niomethacin |
| JP2564386B2 (ja) * | 1987-04-16 | 1996-12-18 | クリスチャン ビンチャエドラー | 水不溶性ポリマーの粉末の調整方法 |
| US4960814A (en) * | 1988-06-13 | 1990-10-02 | Eastman Kodak Company | Water-dispersible polymeric compositions |
-
1990
- 1990-03-05 US US07/489,166 patent/US5326572A/en not_active Expired - Fee Related
- 1990-03-22 CA CA002012853A patent/CA2012853A1/en not_active Abandoned
- 1990-03-22 AT AT90105437T patent/ATE130511T1/de not_active IP Right Cessation
- 1990-03-22 ES ES90105437T patent/ES2079389T3/es not_active Expired - Lifetime
- 1990-03-22 EP EP90105437A patent/EP0388954B1/en not_active Expired - Lifetime
- 1990-03-22 DE DE69023682T patent/DE69023682T2/de not_active Expired - Fee Related
- 1990-03-22 DK DK90105437.9T patent/DK0388954T3/da active
-
1996
- 1996-02-14 GR GR960400371T patent/GR3018970T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2012853A1 (en) | 1990-09-23 |
| US5326572A (en) | 1994-07-05 |
| DE69023682D1 (de) | 1996-01-04 |
| EP0388954A2 (en) | 1990-09-26 |
| EP0388954B1 (en) | 1995-11-22 |
| EP0388954A3 (en) | 1992-09-09 |
| ATE130511T1 (de) | 1995-12-15 |
| GR3018970T3 (en) | 1996-05-31 |
| DE69023682T2 (de) | 1996-04-18 |
| DK0388954T3 (da) | 1995-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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