ES2080099T3 - Ensayo para la hepatitis c. - Google Patents

Ensayo para la hepatitis c.

Info

Publication number
ES2080099T3
ES2080099T3 ES90125354T ES90125354T ES2080099T3 ES 2080099 T3 ES2080099 T3 ES 2080099T3 ES 90125354 T ES90125354 T ES 90125354T ES 90125354 T ES90125354 T ES 90125354T ES 2080099 T3 ES2080099 T3 ES 2080099T3
Authority
ES
Spain
Prior art keywords
test
vch
antigen
sample
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90125354T
Other languages
English (en)
Inventor
Tat Leung
James M Casey
Virender Kumar Sarin
Smriti U Mehta
Sushil G Devare
Richard R Lesniewski
Suresh M Desai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2080099T3 publication Critical patent/ES2080099T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

LA INVENCION PRESENTA UN ENSAYO MEJORADO PARA DETECTAR LA PRESENCIA DE UN ANTICUERPO A UN ANTIGENO VCH EN UNA MUESTRA MEDIANTE LA PUESTA EN CONTACTO DE LA MUESTRA CON UN POLIPEPTIDO QUE CONTIENE UN EPITOPE DE UN ANTIGENO VCH. ENTRE LOS TIPOS DE ENSAYOS PREFERIDOS CABE MENCIONAR UN ENSAYO CONFIRMATORIO, UN ENSAYO DE COMBINACION, UN ENSAYO BASADO EN POLIPEPTIDOS SINTETICOS, UN ENSAYO IMMUNODOT Y UN ENSAYO DE COMPETICION.
ES90125354T 1989-12-22 1990-12-22 Ensayo para la hepatitis c. Expired - Lifetime ES2080099T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45616289A 1989-12-22 1989-12-22
US61018090A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
ES2080099T3 true ES2080099T3 (es) 1996-02-01

Family

ID=27038137

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90125354T Expired - Lifetime ES2080099T3 (es) 1989-12-22 1990-12-22 Ensayo para la hepatitis c.

Country Status (7)

Country Link
EP (1) EP0445423B1 (es)
JP (1) JP3188717B2 (es)
AT (1) ATE128237T1 (es)
AU (1) AU638304B2 (es)
CA (1) CA2032907C (es)
DE (1) DE69022578T2 (es)
ES (1) ES2080099T3 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
DK0398748T3 (da) * 1989-05-18 2002-03-18 Chiron Corp NANBV-diagnostika: polynukleotider anvendelige til screening for hepatitis C virus
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
HU217025B (hu) † 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
CA2079912C (en) * 1990-04-06 2000-07-11 Gregory Reyes Hepatitis c virus epitopes
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
CA2055149A1 (en) * 1990-11-08 1992-05-09 Hiroaki Okamoto Non-a, non-b hepatitis virus related antigen, antibody, detection systems, polynucleotides and polypeptides
KR920703640A (ko) * 1990-11-29 1992-12-18 테루카츄 아리마 비a비b형 간염 바이러스 항원 단백질
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
EP0754704B1 (en) * 1990-12-14 1999-10-06 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
WO1992012992A2 (en) * 1991-01-14 1992-08-06 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
ATE167522T1 (de) * 1991-01-31 1998-07-15 Abbott Lab Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
WO1993000365A2 (en) * 1991-06-24 1993-01-07 Chiron Corporation Hepatitis c virus (hcv) polypeptides
JPH06510188A (ja) * 1991-08-21 1994-11-17 アボツト・ラボラトリーズ 推定ｈｃｖ　ｎｓ５タンパクに対するモノクローナル抗体およびそれを使用する方法
AU2679492A (en) * 1991-09-16 1993-04-27 Abbott Laboratories Hepatitis c assay
DE69232906T2 (de) * 1991-11-21 2004-01-15 Common Services Agency Edinbur Detektion des Hepatis-C Virus.
JPH05176773A (ja) * 1991-12-27 1993-07-20 Imuno Japan:Kk オリゴヌクレオチド、オリゴペプタイド、ならびに抗ｃ型肝 炎ウイルス抗体検出・鑑別方法
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
RU2104284C1 (ru) * 1994-10-20 1998-02-10 Научно-исследовательский институт вирусологии им.Д.И.Ивановского РАМН Синтетические олигопептиды, специфически взаимодействующие с антителами к вирусу гепатита с, способы диагностики hcv-инфекции (варианты)
GB2294690B (en) * 1994-11-01 1998-10-28 United Biomedical Inc Peptides effective for diagnosis and detection of hepatitis C infection
DE19504302A1 (de) * 1995-02-09 1996-08-14 Boehringer Mannheim Gmbh Methode zur serologischen Typisierung mittels typspezifischer Antigene
DE19540105C1 (de) * 1995-09-19 1997-02-20 United Biomedical Inc Peptidzusammensetzungen zur Diagnose und zum Nachweis von Hepatitis C Virus (HCV)-Infektion
WO1999024466A2 (en) * 1997-11-06 1999-05-20 Innogenetics N.V. Multi-mer peptides derived from hepatitis c virus envelope proteins for diagnostic use and vaccination purposes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227011A (en) * 1987-11-18 1992-03-26 Chiron Corp Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용

Also Published As

Publication number Publication date
EP0445423A2 (en) 1991-09-11
EP0445423B1 (en) 1995-09-20
EP0445423A3 (en) 1992-04-29
ATE128237T1 (de) 1995-10-15
AU6839090A (en) 1991-06-27
DE69022578D1 (de) 1995-10-26
CA2032907A1 (en) 1991-06-23
JPH04253998A (ja) 1992-09-09
AU638304B2 (en) 1993-06-24
DE69022578T2 (de) 1996-05-02
JP3188717B2 (ja) 2001-07-16
CA2032907C (en) 2002-05-14

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