ES2084643T3 - Indolilpropanoles, procedimiento para su fabricacion y su uso, asi como preparaciones que contienen los compuestos. - Google Patents

Indolilpropanoles, procedimiento para su fabricacion y su uso, asi como preparaciones que contienen los compuestos.

Info

Publication number
ES2084643T3
ES2084643T3 ES90125016T ES90125016T ES2084643T3 ES 2084643 T3 ES2084643 T3 ES 2084643T3 ES 90125016 T ES90125016 T ES 90125016T ES 90125016 T ES90125016 T ES 90125016T ES 2084643 T3 ES2084643 T3 ES 2084643T3
Authority
ES
Spain
Prior art keywords
indolilpropanoles
compounds
procedure
manufacture
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90125016T
Other languages
English (en)
Inventor
Wolfgang Dr Stenzel
Ben Dr Armah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf Lilly GmbH
Original Assignee
Beiersdorf Lilly GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf Lilly GmbH filed Critical Beiersdorf Lilly GmbH
Application granted granted Critical
Publication of ES2084643T3 publication Critical patent/ES2084643T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROPANOL DE INDOLINA DE LA FORMULA I, EN LA QUE R ELEVADO A 1 Y R (AL CUADRADO) , PUEDEN SER IGUALES O DISTINTAS, Y QUE SIGNIFICAN CADA UNA FENILO O, EN SU CASO, A TRAVES DE HALOGENOS, ALQUILO, C SUB 3-7-CICLOALQUILO O C SUB 1-6-ALCOXI MONOSUSTITUYENTES DE FENILO O DIFERENTES SUSTITUYENTES DE FENILOL, UN 2-, 3ALQUILO SIGNIFICA UNA CADENA DERECHA DE ALQUILO CON 1 HASTA 6 ATOMOS DE CARBONO O DERIVADOS DE ALQUILO CON 3 HASTA 6 ATOMOS DE CARBONO. SUS SALES Y SALES ADICIONALES DE ACIDO, TAUTOMEROS E ISOMEROS OPTICOS MUESTRAN UNA EFICACIA POSITIVA E INOTROPE Y ANTIARRITMICA.
ES90125016T 1990-01-27 1990-12-20 Indolilpropanoles, procedimiento para su fabricacion y su uso, asi como preparaciones que contienen los compuestos. Expired - Lifetime ES2084643T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4002391A DE4002391A1 (de) 1990-01-27 1990-01-27 Indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen

Publications (1)

Publication Number Publication Date
ES2084643T3 true ES2084643T3 (es) 1996-05-16

Family

ID=6398895

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90125016T Expired - Lifetime ES2084643T3 (es) 1990-01-27 1990-12-20 Indolilpropanoles, procedimiento para su fabricacion y su uso, asi como preparaciones que contienen los compuestos.

Country Status (11)

Country Link
US (1) US5145849A (es)
EP (1) EP0439796B1 (es)
JP (1) JP3253096B2 (es)
KR (1) KR100202291B1 (es)
AT (1) ATE133413T1 (es)
AU (1) AU636192B2 (es)
CA (1) CA2033771C (es)
DE (2) DE4002391A1 (es)
DK (1) DK0439796T3 (es)
ES (1) ES2084643T3 (es)
ZA (1) ZA91118B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843938A (en) * 1995-10-03 1998-12-01 Beiersdorf-Lilly Gmbh Treatment of atherosclerosis
CA2228938A1 (en) * 1995-10-03 1997-04-10 Beiersdorf-Lilly Gmbh Treatment of atherosclerosis
EP0766962A3 (en) * 1995-10-03 2000-05-10 Beiersdorf-Lilly GmbH Treatment of atherosclerosis
US7334064B2 (en) * 2003-04-23 2008-02-19 Dot Hill Systems Corporation Application server blade for embedded storage appliance

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
EP0013878A1 (en) * 1979-01-18 1980-08-06 Sandoz Ag 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3524955A1 (de) * 1984-07-19 1986-01-30 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
GB2163150B (en) * 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
DE3723648A1 (de) * 1987-07-17 1989-01-26 Sandoz Ag Indol-derivate, ihre herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
ZA91118B (en) 1991-10-30
DE4002391A1 (de) 1991-08-01
AU6990391A (en) 1991-08-01
EP0439796A3 (en) 1992-01-22
ATE133413T1 (de) 1996-02-15
CA2033771C (en) 2001-03-27
KR910014371A (ko) 1991-08-31
EP0439796A2 (de) 1991-08-07
JPH04210979A (ja) 1992-08-03
US5145849A (en) 1992-09-08
DE59010091D1 (de) 1996-03-07
KR100202291B1 (ko) 1999-06-15
JP3253096B2 (ja) 2002-02-04
EP0439796B1 (de) 1996-01-24
DK0439796T3 (da) 1996-02-12
AU636192B2 (en) 1993-04-22
CA2033771A1 (en) 1991-07-28

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