ES2087252T3 - Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol. - Google Patents

Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol.

Info

Publication number
ES2087252T3
ES2087252T3 ES91309685T ES91309685T ES2087252T3 ES 2087252 T3 ES2087252 T3 ES 2087252T3 ES 91309685 T ES91309685 T ES 91309685T ES 91309685 T ES91309685 T ES 91309685T ES 2087252 T3 ES2087252 T3 ES 2087252T3
Authority
ES
Spain
Prior art keywords
cholesterol
metabolism
dioxabiciclo
octano
medication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91309685T
Other languages
English (en)
Inventor
Kengo Akimoto
Sumio Asami
Michihiro Sugano
Nobuaki Hirose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17644733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2087252(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2087252T3 publication Critical patent/ES2087252T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE DESCRIBE UN METODO PARA INHIBIR EL METABOLISMO DEL COLESTEROL, QUE CONSISTE EN LA ADMINISTRACION AL SUJETO DE UNA COMPOSICION FARMACOLOGICA QUE COMPRENDE UN DERIVADO DEL DIOXABICICLO[3.3.0]OCTANO REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL (I): DONDE R ELEVADO 1, R (AL CUADRADO) , R ELEVADO 3, R ELEVADO 4 Y R ELEVADO 5 INDEPENDIENTEMENTE REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO QUE TIENE DE 1 A 3 ATOMOS DE CARBONO, O R ELEVADO 1 Y R (AL CUADRADO) Y/O R ELEVADO 4 Y R ELEVADO 5 CONJUNTAMENTE FORMAN UN GRUPO METILENO O UN GRUPO ETILENO, Y N, M Y L SON 0 O 1.
ES91309685T 1990-10-22 1991-10-21 Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol. Expired - Lifetime ES2087252T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28183990A JP3183664B2 (ja) 1990-10-22 1990-10-22 コレステロール及び胆汁酸の代謝阻害剤

Publications (1)

Publication Number Publication Date
ES2087252T3 true ES2087252T3 (es) 1996-07-16

Family

ID=17644733

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91309685T Expired - Lifetime ES2087252T3 (es) 1990-10-22 1991-10-21 Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol.

Country Status (9)

Country Link
US (1) US5270335A (es)
EP (1) EP0488513B1 (es)
JP (1) JP3183664B2 (es)
AT (1) ATE138571T1 (es)
CA (1) CA2053820C (es)
DE (1) DE69119875T2 (es)
DK (1) DK0488513T3 (es)
ES (1) ES2087252T3 (es)
GR (1) GR3020682T3 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3283274B2 (ja) * 1991-06-15 2002-05-20 サントリー株式会社 新規組成物
JPH06227977A (ja) * 1993-02-01 1994-08-16 Suntory Ltd 活性酸素消去剤
US5397778A (en) * 1994-02-25 1995-03-14 New England Deaconess Hospital Corporation Enteral formulations for treatment of inflammation and infection
JPH10500937A (ja) * 1994-02-25 1998-01-27 ニュー イングランド ディーコネス ホスピタル コーポレイション セサミン系リグナンの抗炎症及び感染防護効果
JP3818680B2 (ja) * 1994-05-12 2006-09-06 サントリー株式会社 アレルギー症状の予防又は改善剤
ES2202454T3 (es) * 1995-07-04 2004-04-01 Suntory Limited Uso de un agente equilibrante para acidos grasos insaturados omega-3 y omega-6.
JPH11246427A (ja) * 1998-03-04 1999-09-14 Kadoya Sesami Mills Inc 糖・脂質代謝活性化剤
KR100352269B1 (ko) * 1999-10-08 2002-09-12 한국생명공학연구원 저밀도 지질 단백질에 대해 항산화 활성을 갖는 리그난계 화합물
JP4388248B2 (ja) * 2001-10-29 2009-12-24 株式会社日立製作所 最適ポートフォリオ決定方法および装置
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source
JP5096138B2 (ja) * 2005-03-31 2012-12-12 サントリーホールディングス株式会社 リグナン類化合物含有水中油滴型エマルション及びそれを含有する組成物
US7943663B2 (en) 2005-09-30 2011-05-17 Suntory Holdings Limited Process and an apparatus for producing episesamin-rich compositions
SG10201601998PA (en) 2006-03-31 2016-04-28 Suntory Holdings Ltd Jp Compositions containing lignan-class compounds
US20100063142A1 (en) 2006-10-04 2010-03-11 Toshihiro Nishiumi o/w/o EMULSION CONTAINING LIGNAN COMPOUNDS AND COMPOSITION CONTAINING THE SAME
JP5051878B2 (ja) * 2007-03-02 2012-10-17 竹本油脂株式会社 高濃度セサミノール含有物の製造方法
JP5450075B2 (ja) 2007-09-19 2014-03-26 サントリーホールディングス株式会社 セサミン類とビタミンｂ１類とを配合した組成物
JP7366991B2 (ja) * 2019-02-28 2023-10-23 株式会社えがお 体重増加抑制・低減用組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69034181T2 (de) * 1989-07-21 2006-01-26 Suntory Ltd. Kapsel, enthaltend ein Dioxabicyclo(3.3.0)oktan

Also Published As

Publication number Publication date
JPH04159221A (ja) 1992-06-02
DK0488513T3 (da) 1996-06-17
JP3183664B2 (ja) 2001-07-09
CA2053820A1 (en) 1992-04-23
US5270335A (en) 1993-12-14
EP0488513B1 (en) 1996-05-29
DE69119875D1 (de) 1996-07-04
EP0488513A3 (en) 1992-06-17
CA2053820C (en) 1997-02-04
GR3020682T3 (en) 1996-10-31
EP0488513A2 (en) 1992-06-03
ATE138571T1 (de) 1996-06-15
DE69119875T2 (de) 1996-10-02

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