ES2090355T3 - Dispositivo transdermal. - Google Patents
Dispositivo transdermal.Info
- Publication number
- ES2090355T3 ES2090355T3 ES91917418T ES91917418T ES2090355T3 ES 2090355 T3 ES2090355 T3 ES 2090355T3 ES 91917418 T ES91917418 T ES 91917418T ES 91917418 T ES91917418 T ES 91917418T ES 2090355 T3 ES2090355 T3 ES 2090355T3
- Authority
- ES
- Spain
- Prior art keywords
- active ingredient
- pct
- film
- solvents
- solvent mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000004480 active ingredient Substances 0.000 abstract 5
- 239000002904 solvent Substances 0.000 abstract 5
- 239000011877 solvent mixture Substances 0.000 abstract 4
- 239000000853 adhesive Substances 0.000 abstract 3
- 230000001070 adhesive effect Effects 0.000 abstract 3
- 238000009835 boiling Methods 0.000 abstract 3
- 238000001035 drying Methods 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
- Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
- Confectionery (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A UN METODO DE PREPARACION DE UN DISPOSITIVO PARA SUMINISTRO TRANSDERMICO DE UN INGREDIENTE ACTIVO QUE ES SOLIDO A LA TEMPERATURA AMBIENTE Y EN EL QUE PARTE O LA TOTALIDAD DEL INGREDIENTE ACTIVO ESTA PRESENTE EN UNA DISOLUCION SATURADA O SUPERSATURADA, EN DONDE, A MODO DE PRIMER PASO, SE PREPARA UNA MEZCLA QUE INCLUYE AL MENOS UN ADHESIVO POLIMERICO, UN VEHICULO PARA DICHO ADHESIVO, EL INGREDIENTE ACTIVO Y UNA MEZCLA DE DISOLVENTES PARA EL INGREDIENTE ACTIVO QUE COMPRENDE AL MENOS DOS DISOLVENTES. LA MEZCLA SE FORMA EN UNA PELICULA Y SE SECA. EL VEHICULO PARA EL ADHESIVO POLIMERICO Y AL MENOS UNO DE LOS DISOLVENTES EN LA MEZCLA PARA EL INGREDIENTE ACTIVO TIENEN PUNTOS DE EBULLICION POR DEBAJO DE LA TEMPERATURA DE SECADO MIENTRAS QUE AL MENOS UNO DE LOS DISOLVENTES EN LA MEZCLA CON EL INGREDIENTE ACTIVO TIENE UN PUNTO DE EBULLICION POR ENCIMA DE LA TEMPERATURA DE SECADO Y SIENDO LA SOLUBILIDAD DE LOS INGREDIENTES ACTIVOS EN LOS DISOLVENTES DE ALTO PUNTO DE EBULLICIONMAYOR DE 0,5%.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909021674A GB9021674D0 (en) | 1990-10-05 | 1990-10-05 | Transdermal device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2090355T3 true ES2090355T3 (es) | 1996-10-16 |
Family
ID=10683284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91917418T Expired - Lifetime ES2090355T3 (es) | 1990-10-05 | 1991-10-04 | Dispositivo transdermal. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5352457A (es) |
| EP (1) | EP0551349B1 (es) |
| JP (1) | JP2543457B2 (es) |
| AT (1) | ATE137979T1 (es) |
| AU (1) | AU649732B2 (es) |
| CA (1) | CA2093321C (es) |
| DE (1) | DE69119598T2 (es) |
| DK (1) | DK0551349T3 (es) |
| ES (1) | ES2090355T3 (es) |
| GB (2) | GB9021674D0 (es) |
| GR (1) | GR3019929T3 (es) |
| NO (1) | NO302400B1 (es) |
| NZ (1) | NZ240091A (es) |
| WO (1) | WO1992005811A1 (es) |
| ZA (1) | ZA917959B (es) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| GB9118028D0 (en) * | 1991-08-21 | 1991-10-09 | Secr Defence Brit | Improved transdrmal formulations |
| WO1993023019A1 (en) * | 1992-05-11 | 1993-11-25 | Sri International | Transdermal drug delivery systems and related compositions and methods of use |
| HU223042B1 (hu) * | 1993-04-20 | 2004-03-01 | Hexal Ag. | Parkinson-kór kezelésére alkalmas hatóanyagot tartalmazó tapasz |
| US5762952A (en) * | 1993-04-27 | 1998-06-09 | Hercon Laboratories Corporation | Transdermal delivery of active drugs |
| US5494680A (en) * | 1993-12-08 | 1996-02-27 | Minnesota Mining And Manufacturing Company | Transdermal delivery device |
| US5580574A (en) * | 1994-04-28 | 1996-12-03 | Hoffmann-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| US5552153A (en) * | 1994-04-28 | 1996-09-03 | Hoffman-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
| DE19548332A1 (de) * | 1995-12-22 | 1997-07-10 | Rotta Res Bv | Hormonpflaster |
| US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
| DE19649535C2 (de) * | 1996-11-29 | 2000-02-10 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung eines pflasterförmigen therapeutischen Systems |
| IT1290255B1 (it) * | 1997-02-05 | 1998-10-22 | Wallcovering Pubblicita S R L | Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| IT1294748B1 (it) | 1997-09-17 | 1999-04-12 | Permatec Tech Ag | Formulazione per un dispositivo transdermico |
| GB9720470D0 (en) | 1997-09-25 | 1997-11-26 | Ethical Pharmaceuticals South | Inhibition of crystallization in transdermal devices |
| DE19828273B4 (de) * | 1998-06-25 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
| GB9828480D0 (en) * | 1998-12-24 | 1999-02-17 | Dermatech Limited | Transdermal drug delivery system |
| DE19929197A1 (de) * | 1999-06-25 | 2000-12-28 | Novosis Pharma Ag | Transdermalsysteme zur Abgabe von 5-HT3-Rezeptor-Antagonisten und ihre Verwendung zur antiemitischen Behandlung |
| DE19934523A1 (de) * | 1999-07-22 | 2001-01-25 | Novosis Pharma Ag | Transdermalsysteme zur Abgabe von Muscarin-Rezeptor-Antagonisten und ihre Verwendung zur Behandlung von Spasmen der glatten Muskulatur im urologischen Bereich |
| US20050118247A1 (en) * | 2000-07-05 | 2005-06-02 | Gunter Cordes | Method of making ketoprofen patch delivery system |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| ATE485837T1 (de) * | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| JP4358978B2 (ja) * | 2000-09-05 | 2009-11-04 | 日東電工株式会社 | 経皮吸収製剤 |
| CA2460352C (en) * | 2001-08-17 | 2013-05-14 | Lavipharm Laboratories Inc. | Composition and transdermal drug delivery device |
| KR100704825B1 (ko) | 2003-02-21 | 2007-04-09 | 바이엘 쉐링 파마 악티엔게젤샤프트 | Uv 안정성 경피 치료 플라스터 |
| RS20050812A (sr) | 2003-04-30 | 2007-12-31 | Purdue Pharma L.P., | Transdermalni dozni oblik otporan na promene |
| US8790689B2 (en) | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| GB0322342D0 (en) * | 2003-09-23 | 2003-10-22 | Gamble Reed | Skin patch |
| ATE534373T1 (de) | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| US8668925B2 (en) * | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
| US20050202073A1 (en) * | 2004-03-09 | 2005-09-15 | Mylan Technologies, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
| DE102004016779A1 (de) * | 2004-04-01 | 2006-01-19 | Schering Ag | Drospirenonhaltige Zubereitungen zur transdermalen Anwendung |
| US20050222106A1 (en) * | 2004-04-01 | 2005-10-06 | Stefan Bracht | Drospirenone-containing preparations for transdermal use |
| US7425340B2 (en) * | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
| US8252319B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
| SI1814531T1 (sl) | 2004-10-21 | 2010-10-29 | Durect Corp | Transdermalni dostavni sistem |
| US8962013B2 (en) * | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| EP1926474A1 (en) * | 2005-07-21 | 2008-06-04 | Mediplex Corp. | Drug formulation containing a solubilizer for enhancing solubility, absorption, and permeability |
| CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
| EP1964567A1 (de) * | 2007-02-28 | 2008-09-03 | Catriona Joos | Pharmazeutische Zubereitung zur Behandlung der Migräne |
| US20080226698A1 (en) | 2007-03-16 | 2008-09-18 | Mylan Technologies, Inc. | Amorphous drug transdermal systems, manufacturing methods, and stabilization |
| CN101925355B (zh) | 2008-01-28 | 2013-05-29 | 帝国制药株式会社 | 含芬太尼的外用贴剂 |
| CA2726136C (en) * | 2008-05-30 | 2016-11-01 | Mylan Laboratories, Inc. | Stabilized transdermal drug delivery system |
| AU2009270339A1 (en) * | 2008-07-18 | 2010-01-21 | Novasel Australia Pty Ltd | Compositions comprising tea tree oil and methods for the prevention and treatment of cancer |
| AU2009302853B2 (en) | 2008-10-06 | 2014-09-11 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
| WO2012048455A1 (zh) * | 2010-10-12 | 2012-04-19 | 武汉大学 | 一种抗病毒透皮吸收贴片及其制备方法 |
| CN109758665B (zh) * | 2019-03-13 | 2021-05-14 | 郑州佶好生物科技有限公司 | 一种乳康保健贴生产装置及其操作方法 |
| US12109278B2 (en) * | 2021-04-02 | 2024-10-08 | Jenni Mueller | Broad spectrum sunblock transfer film and device |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4031894A (en) * | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
| IL59063A (en) * | 1979-01-11 | 1983-12-30 | Key Pharma | Polymeric diffusion matrix for release of pharmaceutical dosage |
| JPS5843368B2 (ja) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | 消炎鎮痛貼付剤 |
| JPS5984817A (ja) * | 1982-11-08 | 1984-05-16 | Sekisui Chem Co Ltd | 薬剤徐放性製剤 |
| FR2542998B1 (fr) * | 1983-03-24 | 1986-01-31 | Rhone Poulenc Sante | Nouvelle forme transdermale du dinitrate d'isosorbide |
| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
| DE3333240A1 (de) * | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
| GB2156215B (en) * | 1984-03-05 | 1988-03-02 | Nitto Electric Ind Co | Percutaneous absorption type adhesive pharmaceutical preparation |
| US4725439A (en) * | 1984-06-29 | 1988-02-16 | Alza Corporation | Transdermal drug delivery device |
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US4751087A (en) * | 1985-04-19 | 1988-06-14 | Riker Laboratories, Inc. | Transdermal nitroglycerin delivery system |
| DE3517080A1 (de) * | 1985-05-11 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Komponente fuer therapeutische wirkstoffabgabesysteme |
| DE3525767A1 (de) * | 1985-07-19 | 1987-01-22 | Boehringer Ingelheim Kg | Pharmazeutische zubereitung mit kontrollierter und verzoegerter wirkstofffreigabe und verfahren zu deren herstellung |
| DE3634016A1 (de) * | 1986-04-17 | 1987-10-29 | Lohmann Gmbh & Co Kg | Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung |
| JPS62273159A (ja) * | 1986-05-20 | 1987-11-27 | Sumitomo Electric Ind Ltd | アンチロツクシステムにおける電磁弁制御方式 |
| JPH0699299B2 (ja) * | 1986-05-23 | 1994-12-07 | 積水化学工業株式会社 | 経皮吸収性製剤の製造方法 |
| JPS6393174A (ja) * | 1986-10-07 | 1988-04-23 | Nec Corp | フオトダイオ−ド |
| JPS6393715A (ja) * | 1986-10-09 | 1988-04-25 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
| AU601528B2 (en) * | 1986-12-22 | 1990-09-13 | Ortho-Mcneil Pharmaceutical, Inc. | Resilient transdermal drug-delivery device and compositions and devices employing fatty acid esters/ethers of alkanediols and percutaneous absorption enhancers |
| DE3643987A1 (de) * | 1986-12-22 | 1988-06-23 | Lohmann Therapie Syst Lts | Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung |
| CN1021196C (zh) * | 1986-12-29 | 1993-06-16 | 新泽西州州立大学(鲁杰斯) | 透皮雌激素/孕激素药剂单元、系统及方法 |
| US4816258A (en) * | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
| ATE86056T1 (de) * | 1987-09-14 | 1993-03-15 | Autophon Ascom Ag | Telefonstation mit einem teilnehmerverzeichnis. |
| FR2623718B1 (fr) * | 1987-11-27 | 1994-04-15 | Fabre Medicament Pierre | Dispositif therapeutique transdermique et son procede de preparation |
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| GB8804164D0 (en) * | 1988-02-23 | 1988-03-23 | Tucker J M | Bandage for administering physiologically active compound |
| DE68917292T2 (de) * | 1988-02-26 | 1995-02-02 | Riker Laboratories Inc | Transdermales estradiol als therapeutisches sytem. |
| DE3807283A1 (de) * | 1988-03-05 | 1989-09-14 | Basf Ag | Verfahren zur herstellung eines pflasters zur transdermalen anwendung pharmazeutischer wirkstoffe |
| CA2004203A1 (en) * | 1988-12-01 | 1990-06-01 | Sharad K. Govil | Compositions for transdermal delivery of estradiol |
-
1990
- 1990-10-05 GB GB909021674A patent/GB9021674D0/en active Pending
-
1991
- 1991-10-04 AU AU86295/91A patent/AU649732B2/en not_active Ceased
- 1991-10-04 WO PCT/GB1991/001730 patent/WO1992005811A1/en not_active Ceased
- 1991-10-04 US US08/030,265 patent/US5352457A/en not_active Expired - Lifetime
- 1991-10-04 CA CA002093321A patent/CA2093321C/en not_active Expired - Fee Related
- 1991-10-04 DK DK91917418.5T patent/DK0551349T3/da active
- 1991-10-04 JP JP3515975A patent/JP2543457B2/ja not_active Expired - Fee Related
- 1991-10-04 GB GB9121135A patent/GB2249956B/en not_active Expired - Lifetime
- 1991-10-04 AT AT91917418T patent/ATE137979T1/de not_active IP Right Cessation
- 1991-10-04 EP EP91917418A patent/EP0551349B1/en not_active Expired - Lifetime
- 1991-10-04 ES ES91917418T patent/ES2090355T3/es not_active Expired - Lifetime
- 1991-10-04 ZA ZA917959A patent/ZA917959B/xx unknown
- 1991-10-04 DE DE69119598T patent/DE69119598T2/de not_active Expired - Fee Related
- 1991-10-04 NZ NZ240091A patent/NZ240091A/en not_active IP Right Cessation
-
1993
- 1993-04-02 NO NO931279A patent/NO302400B1/no not_active IP Right Cessation
-
1996
- 1996-05-16 GR GR960401273T patent/GR3019929T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3019929T3 (en) | 1996-08-31 |
| DE69119598D1 (de) | 1996-06-20 |
| NO931279L (no) | 1993-04-02 |
| GB2249956B (en) | 1994-07-13 |
| JPH06501932A (ja) | 1994-03-03 |
| NO302400B1 (no) | 1998-03-02 |
| CA2093321C (en) | 1998-11-24 |
| DK0551349T3 (da) | 1996-09-30 |
| EP0551349B1 (en) | 1996-05-15 |
| GB2249956A (en) | 1992-05-27 |
| CA2093321A1 (en) | 1992-04-06 |
| ATE137979T1 (de) | 1996-06-15 |
| NO931279D0 (no) | 1993-04-02 |
| AU8629591A (en) | 1992-04-28 |
| GB9021674D0 (en) | 1990-11-21 |
| ZA917959B (en) | 1992-12-30 |
| JP2543457B2 (ja) | 1996-10-16 |
| GB9121135D0 (en) | 1991-11-13 |
| AU649732B2 (en) | 1994-06-02 |
| WO1992005811A1 (en) | 1992-04-16 |
| US5352457A (en) | 1994-10-04 |
| EP0551349A1 (en) | 1993-07-21 |
| DE69119598T2 (de) | 1996-09-12 |
| NZ240091A (en) | 1993-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2090355T3 (es) | Dispositivo transdermal. | |
| DK0461630T3 (da) | Fremgangsmåde til fremstilling af mikrokugler | |
| SE8403487D0 (sv) | Farmaceutisk komposition | |
| DE69814885D1 (de) | Verfahren zur herstellung von arzneiformen mit kontrollierter wirkstoffabgabe auf polymerbasis | |
| KR900007837A (ko) | 퀴누클리딘, 약제로서 이의 용도 및 이의 제조방법 | |
| KR890700344A (ko) | 약학 제제 | |
| DE60041704D1 (de) | Ungen | |
| PT99168A (pt) | Processo para a producao de uma preparacao farmaceutica para ser administrativa oralmente, contendo nomeadamente um mono- ou dinitrato de isosorbida | |
| EP0116207A3 (en) | Cosmetic formulation | |
| ES2069814T3 (es) | Composiciones de resina epoxidica que contienen poliacetoacetato. | |
| KR960704911A (ko) | 2',5'-올리고아데닐레이트-2',3'- 시클로포스페이트 (2',5'-oligoadenylate-2',3'-cyclophosphates) | |
| ES2012118A6 (es) | Procedimiento de obtencion de soluciones solidas de compuestos farmaceuticamente activos. | |
| ATE235422T1 (de) | Gelierungsstabiele polyhalogenphosphazenverbindungen | |
| JPS5332109A (en) | Injection | |
| DK144417C (da) | Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive alfa-(3,4-dimethoxyphenethylaminomethyl)-2-alkoxybenzylalkoholer eller farmaceutisk anvendelige syreadditionssalte deraf | |
| ATE35620T1 (de) | Pharmazeutische zubereitung mit retardwirkung. | |
| KR880012226A (ko) | 외 용 제 | |
| JPS5742618A (en) | Plaster and its preparation | |
| DE69827120D1 (de) | Verfahren zur entfernung von hochsiedenden lösemitteln aus wirkstoffformulierungen mittels vakuum trocknung | |
| JPS5445153A (en) | Polarizing film | |
| JPS5318696A (en) | Novel aromatic polyamides | |
| JPS5212676A (en) | Solution condensing apparatus | |
| JPS5375297A (en) | Polymerization of 4,4'-thiobis (6-tertialbutyl-m-cresol) | |
| JPS51133426A (en) | A method for detecting activities of insecticides | |
| NL7609304A (nl) | Vinylthiofosfor (fosfon) zuuresters en -ester- amiden en insecticide en acaricide middelen alsmede werkwijze voor het bereiden daarvan. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 551349 Country of ref document: ES |
|
| FG2A | Definitive protection |
Ref document number: 551349 Country of ref document: ES |