ES2091752T3 - Medios y procedimiento para la obtencion de un polipeptido de la interleucina-1 alfa humana, recombinante. - Google Patents

Medios y procedimiento para la obtencion de un polipeptido de la interleucina-1 alfa humana, recombinante.

Info

Publication number
ES2091752T3
ES2091752T3 ES89100402T ES89100402T ES2091752T3 ES 2091752 T3 ES2091752 T3 ES 2091752T3 ES 89100402 T ES89100402 T ES 89100402T ES 89100402 T ES89100402 T ES 89100402T ES 2091752 T3 ES2091752 T3 ES 2091752T3
Authority
ES
Spain
Prior art keywords
recombinant
polypeptide
procedure
obtaining
interleukin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89100402T
Other languages
English (en)
Inventor
Peter T Lomedico
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2091752T3 publication Critical patent/ES2091752T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PATENTE AFECTA A POLIPEPTIDOS INTERLEUKIN - 1(ALFA) HOMOGENEOS RECOMBINENTES HUMANOS, SECUENCIAS DE DNA QUE CODIFICAN ESTOS POLIPEPTIDOS, VECTORES RECOMBINANTES QUE CONTIENEN ESTE DNA, ORGANISMOS HUESPED QUE CONTIENEN UN VECTOR RECOMBINANTE DE ESTE TIPO Y METODOS PARA LA OBTENCION DE LOS POLIPEPTIDOS CITADOS. LOS POLIPEPTIDOS HUMANOS RECOMBINANTES INTERLEUKIN - 1(ALFA) Y LOS COMPUESTOS FARMACEUTICOS QUE LOS CONTIENEN SE PUEDEN UTILIZAR PARA LA ESTIMULACION DEL SISTEMA INMUNOLOGICO DE UN PACIENTE, PARA FACILITAR LA CURACION DE HERIDAS O PARA FACILITAR LA CURACION DE PACIENTES GRAVES SUBALIMENTADOS PROTEICAMENTE.
ES89100402T 1988-01-15 1989-01-11 Medios y procedimiento para la obtencion de un polipeptido de la interleucina-1 alfa humana, recombinante. Expired - Lifetime ES2091752T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14445788A 1988-01-15 1988-01-15

Publications (1)

Publication Number Publication Date
ES2091752T3 true ES2091752T3 (es) 1996-11-16

Family

ID=22508674

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89100402T Expired - Lifetime ES2091752T3 (es) 1988-01-15 1989-01-11 Medios y procedimiento para la obtencion de un polipeptido de la interleucina-1 alfa humana, recombinante.

Country Status (19)

Country Link
EP (1) EP0324447B1 (es)
JP (1) JP2567079B2 (es)
AR (1) AR245958A1 (es)
AT (1) ATE142696T1 (es)
AU (1) AU616461B2 (es)
DE (1) DE58909723D1 (es)
DK (1) DK16489A (es)
ES (1) ES2091752T3 (es)
FI (1) FI890175L (es)
GR (1) GR3021887T3 (es)
HU (1) HU208996B (es)
IE (1) IE890087L (es)
IL (1) IL88934A (es)
MC (1) MC2002A1 (es)
NO (1) NO890174L (es)
NZ (1) NZ227594A (es)
PT (1) PT89438B (es)
YU (1) YU6889A (es)
ZA (1) ZA89202B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.
DE3818660A1 (de) * 1987-06-05 1988-12-15 Colgate Palmolive Co Freifliessendes, pulvriges geschirrwaschmittel und verfahren zur herstellung desselben
KR960008010B1 (ko) * 1988-07-29 1996-06-19 오오쓰까세이야꾸 가부시끼가이샤 IL-1α 유도체 및 혈소판 감소증 치료 약제
US6191269B1 (en) * 1997-05-30 2001-02-20 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US7176179B1 (en) 1997-05-30 2007-02-13 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US20030154504A1 (en) 1998-06-24 2003-08-14 Farese Robert V. Methods and compositions for modulating carbohydrate metabolism
DE10252634A1 (de) * 2002-11-11 2004-05-27 Umwelttechnik Georg Fritzmeier Gmbh & Co. Reinigungsmittel und Verfahren zu seiner Herstellung
US20120219511A1 (en) * 2009-09-29 2012-08-30 Igor Arturovich Petropavlov Oral care compositions containing human recombinant interleukin-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.
DE3683186D1 (de) * 1985-04-25 1992-02-13 Hoffmann La Roche Rekombinantes humaninterleukin-1.
DE3515217A1 (de) * 1985-04-26 1986-10-30 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur messung schwacher magnetfelder
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha

Also Published As

Publication number Publication date
ATE142696T1 (de) 1996-09-15
EP0324447A3 (de) 1990-01-31
NO890174L (no) 1989-07-17
ZA89202B (en) 1989-09-27
IL88934A (en) 1994-05-30
FI890175A7 (fi) 1989-07-16
JP2567079B2 (ja) 1996-12-25
YU6889A (en) 1990-08-31
FI890175L (fi) 1989-07-16
PT89438A (pt) 1990-02-08
AR245958A1 (es) 1994-03-30
HU208996B (en) 1994-09-28
EP0324447B1 (de) 1996-09-11
FI890175A0 (fi) 1989-01-13
GR3021887T3 (en) 1997-03-31
MC2002A1 (fr) 1990-01-26
IL88934A0 (en) 1989-08-15
HUT50505A (en) 1990-02-28
JPH025892A (ja) 1990-01-10
EP0324447A2 (de) 1989-07-19
NO890174D0 (no) 1989-01-13
DE58909723D1 (de) 1996-10-17
IE890087L (en) 1989-07-15
AU2850989A (en) 1989-07-20
PT89438B (pt) 1993-09-30
NZ227594A (en) 1991-09-25
AU616461B2 (en) 1991-10-31
DK16489D0 (da) 1989-01-13
DK16489A (da) 1989-07-16

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