ES2096724T3 - Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico. - Google Patents

Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico.

Info

Publication number
ES2096724T3
ES2096724T3 ES92307140T ES92307140T ES2096724T3 ES 2096724 T3 ES2096724 T3 ES 2096724T3 ES 92307140 T ES92307140 T ES 92307140T ES 92307140 T ES92307140 T ES 92307140T ES 2096724 T3 ES2096724 T3 ES 2096724T3
Authority
ES
Spain
Prior art keywords
propionico
isobutilfenil
acid
optical resolution
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92307140T
Other languages
English (en)
Inventor
Hiroyuki Nohira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagase and Co Ltd
Original Assignee
Nagase and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase and Co Ltd filed Critical Nagase and Co Ltd
Application granted granted Critical
Publication of ES2096724T3 publication Critical patent/ES2096724T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN ACIDO ( (MAS MENOS) )-2-(4-ISOBUTILFENILO)-PROPIONICO PUEDE SER RESUELTO EN ISOMEROS OPTICAMENTE ACTIVOS FACILMENTE Y CON ALTOS RENDIMIENTOS. EL METODO SE CARACTERIZA PRO EL USO DE LA AMINA OPTICAMENTE ACTIVA DE LA SIGUIENTE FORMULA GENERAL (I) O (II) COMO UN AGENTE DE RESOLUCION.
ES92307140T 1991-08-23 1992-08-05 Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico. Expired - Lifetime ES2096724T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23721091 1991-08-23

Publications (1)

Publication Number Publication Date
ES2096724T3 true ES2096724T3 (es) 1997-03-16

Family

ID=17012017

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92307140T Expired - Lifetime ES2096724T3 (es) 1991-08-23 1992-08-05 Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico.

Country Status (8)

Country Link
US (1) US5321154A (es)
EP (1) EP0529835B1 (es)
JP (1) JP3135696B2 (es)
AT (1) ATE148089T1 (es)
CA (1) CA2074932A1 (es)
DE (1) DE69216952T2 (es)
DK (1) DK0529835T3 (es)
ES (1) ES2096724T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602272A (en) * 1994-06-21 1997-02-11 Bristol-Myers Squibb Company Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes
JPH08151344A (ja) * 1994-09-26 1996-06-11 Nagase & Co Ltd 2−(3−ベンゾイルフェニル)プロピオン酸の光学分割方法
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
DE19624604A1 (de) * 1996-06-20 1998-01-02 Hoechst Ag Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)essigsäuren
IN183408B (es) * 1996-11-20 1999-12-25 Kuraray Co
JP2000080062A (ja) * 1998-07-09 2000-03-21 Sumitomo Chem Co Ltd 光学活性1―アリ―ルアルキルアミン類の製造方法およびその中間体
AU2009315280A1 (en) * 2008-11-14 2010-05-20 Watson Pharma Private Limited Process for the preparation of ramelteon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
GB1596033A (en) * 1978-04-25 1981-08-19 Boots Co Ltd (-)-(2-methoxyphenyl) ethylamine
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
JPS59152346A (ja) * 1983-02-18 1984-08-31 Hiroyuki Nohira 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法
JPS60228442A (ja) * 1984-04-27 1985-11-13 Nissan Chem Ind Ltd 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法
JPH0684332B2 (ja) * 1985-06-20 1994-10-26 住友化学工業株式会社 a−イソプロピル−p−クロルフエニル酢酸の光学分割法
JPS63227543A (ja) * 1987-03-17 1988-09-21 Nippon Kayaku Co Ltd 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法
US5011989A (en) * 1987-10-09 1991-04-30 Sumitomo Chemical Company, Limited Optically active hydroxybenzylamine
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
CA2023954C (en) * 1989-10-17 1999-05-04 Hiroyuki Nohira Process for the optical resolution of 2-(3-benzoyl) phenylpropionic acid
US5015764A (en) * 1990-06-18 1991-05-14 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids

Also Published As

Publication number Publication date
JPH05229986A (ja) 1993-09-07
EP0529835B1 (en) 1997-01-22
DE69216952T2 (de) 1997-07-10
EP0529835A2 (en) 1993-03-03
US5321154A (en) 1994-06-14
DE69216952D1 (de) 1997-03-06
JP3135696B2 (ja) 2001-02-19
CA2074932A1 (en) 1993-02-24
EP0529835A3 (en) 1993-04-28
DK0529835T3 (da) 1997-06-30
ATE148089T1 (de) 1997-02-15

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