ES2148175T3 - Composicion farmaceutica que contiene una sal de ibuprofeno. - Google Patents

Composicion farmaceutica que contiene una sal de ibuprofeno.

Info

Publication number
ES2148175T3
ES2148175T3 ES92909270T ES92909270T ES2148175T3 ES 2148175 T3 ES2148175 T3 ES 2148175T3 ES 92909270 T ES92909270 T ES 92909270T ES 92909270 T ES92909270 T ES 92909270T ES 2148175 T3 ES2148175 T3 ES 2148175T3
Authority
ES
Spain
Prior art keywords
isobutylphenyl
salt
ibuprofen
pharmaceutical composition
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92909270T
Other languages
English (en)
Inventor
Bernard John Armitage
Paul Frederick Coe
John Francis Lampard
Alan Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26298899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2148175(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919110342A external-priority patent/GB9110342D0/en
Priority claimed from GB919112058A external-priority patent/GB9112058D0/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of ES2148175T3 publication Critical patent/ES2148175T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

SE DESCRIBE EL USO DE 2-$-ISOBUTILFENIL)PROPIONATO DE S(-) SODIO (LA SAL DE SODIO DE S+)-IBUPROFENO) EN COMPOSICIONES FARMACEUTICAS PARA EL TRATAMIENTO DE INFLAMACION, DOLOR Y PIREXIA. LAS COMPOSICIONES PREFERIDAS COMPRENDEN DIHIDRATO DE 2-(4ISOBUTILFENIL)PROPIONATO DE S(-) SODIO. TAMBIEN SE DESCRIBEN PROCESOS PARA PREPARAR 2-(4-ISOBUTILFENIL)PROPIONATO DE S-(-)SODIO Y SU USO EN UN PROCESO PARA PREPARAR ACIDO S(+) 2-(4-ISOBUTILFENIL)PROPIONICO DE ALTA PUREZA ENANTIOMERICA.
ES92909270T 1991-05-13 1992-05-04 Composicion farmaceutica que contiene una sal de ibuprofeno. Expired - Lifetime ES2148175T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110342A GB9110342D0 (en) 1991-05-13 1991-05-13 Therapeutic agent
GB919112058A GB9112058D0 (en) 1991-06-05 1991-06-05 Therapeutic agent

Publications (1)

Publication Number Publication Date
ES2148175T3 true ES2148175T3 (es) 2000-10-16

Family

ID=26298899

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92909270T Expired - Lifetime ES2148175T3 (es) 1991-05-13 1992-05-04 Composicion farmaceutica que contiene una sal de ibuprofeno.

Country Status (32)

Country Link
US (3) US6525214B1 (es)
EP (1) EP0584108B1 (es)
JP (1) JP3326174B2 (es)
KR (1) KR100198044B1 (es)
CN (1) CN1068305C (es)
AT (1) ATE195417T1 (es)
AU (1) AU658415B2 (es)
BG (1) BG61676B1 (es)
CA (1) CA2102530C (es)
CZ (1) CZ281717B6 (es)
DE (1) DE69231359T2 (es)
DK (1) DK0584108T3 (es)
EG (1) EG20309A (es)
ES (1) ES2148175T3 (es)
FI (1) FI109994B (es)
GE (1) GEP20002013B (es)
GR (1) GR3034780T3 (es)
HU (1) HU219242B (es)
IE (1) IE921393A1 (es)
IL (1) IL101818A (es)
MX (1) MX9202215A (es)
MY (1) MY110267A (es)
NO (2) NO304678B1 (es)
NZ (1) NZ242640A (es)
PT (1) PT100476B (es)
RO (1) RO118371B1 (es)
RU (1) RU2145219C1 (es)
SK (1) SK279279B6 (es)
TW (1) TW304940B (es)
UA (1) UA34430C2 (es)
WO (1) WO1992020334A1 (es)
YU (1) YU48928B (es)

Families Citing this family (59)

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KR100198044B1 (ko) * 1991-05-13 1999-06-15 아이 에이 호틴 이부프로펜 염을 포함하는 약제학적 조성물
US5260482A (en) * 1992-10-14 1993-11-09 Ethyl Corporation Enantiomeric resolution
US5248813A (en) † 1992-10-14 1993-09-28 Ethyl Corporation Enantiomeric resolution
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
ATE180668T1 (de) * 1992-12-01 1999-06-15 Spirig Ag S(+)-ibuprofen enthaltende arzneimittel
AU672269B2 (en) * 1992-12-02 1996-09-26 Aesica Pharmaceuticals Ltd Process for preparing substantially pure enantiomers of phenylpropionic acids
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
IT1270239B (it) * 1994-06-17 1997-04-29 Zambon Spa Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
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US20050063998A1 (en) * 1999-10-26 2005-03-24 Francois Marc Karel Jozef Oral solution containing galantamine and a sweetening agent
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EA005494B1 (ru) * 2000-08-25 2005-02-24 Кова Компани, Лтд. Жидкая загрузочная композиция для капсул с ибупрофеном и препарат в виде капсул
JP2002069030A (ja) * 2000-08-30 2002-03-08 Kyowa Hakko Kogyo Co Ltd ナトリウム２−｛４−［（２−オキソシクロペンチル）メチル］フェニル｝プロピオネート２水和物の製造法
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US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
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US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
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WO2010050499A1 (ja) * 2008-10-29 2010-05-06 三菱瓦斯化学株式会社 光学活性有機カルボン酸の製造方法
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
ES2654331T3 (es) * 2009-06-22 2018-02-13 Wyeth Llc Comprimidos de ibuprofeno de sodio y procedimientos de fabricación de composiciones farmacéuticas que incluyen ibuprofeno de sodio
JP2013514347A (ja) * 2009-12-16 2013-04-25 シャスン ファーマシューティカルズ リミテッド デクスイブプロフェン経皮ヒドロゲルの組成物
CN102557918B (zh) * 2011-11-28 2013-08-21 海南永田药物研究院有限公司 一种布洛芬钠化合物及其制法
WO2013154511A1 (en) * 2012-04-13 2013-10-17 Mahmut Bilgic Film tablet formulations comprising dexibuprofen
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CN102992997A (zh) * 2012-11-20 2013-03-27 北京阜康仁生物制药科技有限公司 右布洛芬的新药用盐
CN104744236A (zh) * 2013-12-26 2015-07-01 鲁南贝特制药有限公司 一种右旋布洛芬的精制方法
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US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
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Also Published As

Publication number Publication date
IL101818A (en) 1999-08-17
DE69231359D1 (de) 2000-09-21
NZ242640A (en) 1993-11-25
HU9303220D0 (en) 1994-03-28
MX9202215A (es) 1992-11-01
JP3326174B2 (ja) 2002-09-17
TW304940B (es) 1997-05-11
PT100476B (pt) 1999-09-30
KR100198044B1 (ko) 1999-06-15
GR3034780T3 (en) 2001-02-28
IE921393A1 (en) 1992-11-18
IL101818A0 (en) 1992-12-30
FI934964L (fi) 1993-11-10
EP0584108A1 (en) 1994-03-02
BG61676B1 (bg) 1998-03-31
CA2102530C (en) 2003-07-29
JPH06507159A (ja) 1994-08-11
NO934102L (no) 1993-11-12
PT100476A (pt) 1993-08-31
SK279279B6 (sk) 1998-09-09
UA34430C2 (uk) 2001-03-15
EG20309A (en) 1998-10-31
CN1068734A (zh) 1993-02-10
HUT67034A (en) 1995-01-30
NO982500D0 (no) 1998-06-02
DE69231359T2 (de) 2001-02-08
BG98214A (bg) 1994-07-29
ATE195417T1 (de) 2000-09-15
FI109994B (fi) 2002-11-15
NO305696B1 (no) 1999-07-12
CA2102530A1 (en) 1992-11-14
MY110267A (en) 1998-03-31
US5696165B1 (en) 2000-12-05
US5696165A (en) 1997-12-09
CN1068305C (zh) 2001-07-11
SK125993A3 (en) 1994-04-06
WO1992020334A1 (en) 1992-11-26
CZ281717B6 (cs) 1996-12-11
FI934964A0 (fi) 1993-11-10
US6525214B1 (en) 2003-02-25
NO982500L (no) 1993-11-12
AU1671192A (en) 1992-12-30
YU50292A (sh) 1995-03-27
AU658415B2 (en) 1995-04-13
GEP20002013B (en) 2000-04-10
NO934102D0 (no) 1993-11-12
YU48928B (sh) 2002-12-10
US6242000B1 (en) 2001-06-05
EP0584108B1 (en) 2000-08-16
CZ240593A3 (en) 1994-03-16
HU219242B (en) 2001-03-28
DK0584108T3 (da) 2000-10-09
RU2145219C1 (ru) 2000-02-10
NO304678B1 (no) 1999-02-01
RO118371B1 (ro) 2003-05-30

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