ES2099159T3 - Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos. - Google Patents
Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos.Info
- Publication number
- ES2099159T3 ES2099159T3 ES91911030T ES91911030T ES2099159T3 ES 2099159 T3 ES2099159 T3 ES 2099159T3 ES 91911030 T ES91911030 T ES 91911030T ES 91911030 T ES91911030 T ES 91911030T ES 2099159 T3 ES2099159 T3 ES 2099159T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- lipase
- medicines
- new
- dna sequences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004882 Lipase Human genes 0.000 title abstract 2
- 108090001060 Lipase Proteins 0.000 title abstract 2
- 239000004367 Lipase Substances 0.000 title abstract 2
- 235000019421 lipase Nutrition 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 239000003833 bile salt Substances 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
LA INVENCION SE REFIERE A NUEVAS SECUENCIAS DE DNA, A NUEVAS PROTEINAS CODIFICADAS PARA DICHAS SECUENCIAS DE DNA, Y AL USO DE TALES PROTEINAS. LA INVENCION TAMBIEN PRESENTA VECTORES, TAL COMO CONSTRUCCIONES PLASMIDAS, QUE COMPRENDEN TALES SECUENCIAS DE DNA, QUE SON CAPACES DE EXPRESAR LA ENZIMA DESEADA. LA INVENCION TAMBIEN INCLUYE ORGANISMOS ANFITRIONES TRANSFECTADOS CON TALES CONSTRUCCIONES, POR EJEMPLO LEVADURA DE BACTERIAS, CELULAS DE MAMIFEROS, Y ANIMALES TRANSGENICAS. LA INVENCION TAMBIEN INCLUYE UN PROCESO PARA LA PREPARACION DE LOS NUEVOS PRODUCTOS DE LA INVENCION. LAS NUEVAS PROTEINAS ESTAN RELACIONADAS CON UNA ENZIMA, CONOCIDA COMO LIPASA ESTIMULADA POR LA SAL DE BILIS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9001985A SE9001985D0 (sv) | 1990-06-01 | 1990-06-01 | New chemical products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2099159T3 true ES2099159T3 (es) | 1997-05-16 |
Family
ID=20379662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91911030T Expired - Lifetime ES2099159T3 (es) | 1990-06-01 | 1991-05-30 | Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos. |
Country Status (44)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5616483A (en) * | 1992-06-11 | 1997-04-01 | Aktiebolaget Astra | Genomic DNA sequences encoding human BSSL/CEL |
| IS4130A (is) * | 1993-03-01 | 1994-09-02 | Ab Astra | Ný fjölpeptíð |
| SE9300686D0 (sv) | 1993-03-01 | 1993-03-01 | Astra Ab | Novel polypeptides |
| FR2754827B1 (fr) * | 1996-10-17 | 1998-12-24 | Biocem | Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| JP2000026311A (ja) * | 1998-07-02 | 2000-01-25 | Amano Pharmaceut Co Ltd | 胃排出能亢進剤組成物 |
| EP1963524A2 (en) * | 2005-12-01 | 2008-09-03 | University of Bergen | Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes using human cel gene |
| MX338426B (es) | 2010-04-23 | 2016-04-15 | Synageva Biopharma Corp | Enzima de enfermedad del almacenamiento lisosomico. |
| DK2613798T4 (en) | 2010-09-09 | 2018-04-16 | Synageva Biopharma Corp | USING LYSOSOMAL SUR LIPASE TO TREAT PATIENTS WITHOUT LYSOSOMAL SUR LIPASE |
| CA2812852A1 (en) | 2010-10-21 | 2012-04-26 | Swedish Orphan Biovitrum Ab (Publ) | Method to increase the absorption of unsaturated fatty acids by human infants |
| DK2629790T3 (en) * | 2010-10-21 | 2016-10-24 | Swedish Orphan Biovitrum Ab (Publ) | Approach to increase growth rate of human babies |
| KR20200018781A (ko) * | 2017-06-19 | 2020-02-20 | 스위디쉬 오르펀 바이오비트럼 에이비 (피유비엘) | 반감기 연장 폴리펩티드를 갖는 융합 단백질 |
| MX2022002473A (es) | 2019-08-30 | 2022-08-02 | Codexis Inc | Variantes de lipasa modificadas geneticamente. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3107684A (en) * | 1983-07-01 | 1985-02-07 | Celltech Limited | Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production |
-
1990
- 1990-06-01 SE SE9001985A patent/SE9001985D0/xx unknown
-
1991
- 1991-05-17 ZA ZA913778A patent/ZA913778B/xx unknown
- 1991-05-18 TW TW080103838A patent/TW221712B/zh not_active IP Right Cessation
- 1991-05-20 DZ DZ910064A patent/DZ1503A1/fr active
- 1991-05-22 NZ NZ238223A patent/NZ238223A/xx not_active IP Right Cessation
- 1991-05-23 MY MYPI91000877A patent/MY111245A/en unknown
- 1991-05-27 IL IL9827391A patent/IL98273A/xx not_active IP Right Cessation
- 1991-05-29 YU YU95191A patent/YU49138B/sh unknown
- 1991-05-29 MA MA22438A patent/MA22166A1/fr unknown
- 1991-05-29 EG EG33391A patent/EG19937A/xx active
- 1991-05-30 AT AT91911030T patent/ATE151077T1/de not_active IP Right Cessation
- 1991-05-30 PL PL91296937A patent/PL166534B1/pl unknown
- 1991-05-30 HU HU9203774A patent/HU215258B/hu unknown
- 1991-05-30 WO PCT/SE1991/000381 patent/WO1991018923A1/en not_active Ceased
- 1991-05-30 EP EP91911030A patent/EP0535048B1/en not_active Expired - Lifetime
- 1991-05-30 JP JP91510382A patent/JPH05507201A/ja active Pending
- 1991-05-30 SG SG1996006887A patent/SG48078A1/en unknown
- 1991-05-30 UA UA93003780A patent/UA39165C2/uk unknown
- 1991-05-30 RO RO92-01490A patent/RO114793B1/ro unknown
- 1991-05-30 RU RU92016526/13A patent/RU2140983C1/ru active
- 1991-05-30 DE DE69125489T patent/DE69125489T2/de not_active Expired - Lifetime
- 1991-05-30 DK DK91911030.4T patent/DK0535048T3/da active
- 1991-05-30 IE IE184491A patent/IE911844A1/en not_active IP Right Cessation
- 1991-05-30 AU AU79645/91A patent/AU651979B2/en not_active Expired
- 1991-05-30 CA CA002083396A patent/CA2083396C/en not_active Expired - Lifetime
- 1991-05-30 ES ES91911030T patent/ES2099159T3/es not_active Expired - Lifetime
- 1991-05-31 CZ CS19911644A patent/CZ287470B6/cs not_active IP Right Cessation
- 1991-05-31 IS IS3710A patent/IS1751B/is unknown
- 1991-05-31 SK SK1644-91A patent/SK281089B6/sk not_active IP Right Cessation
- 1991-05-31 PT PT97836A patent/PT97836B/pt not_active IP Right Cessation
- 1991-05-31 TN TNTNSN91041A patent/TNSN91041A1/fr unknown
- 1991-06-01 JO JO19911694A patent/JO1694B1/en active
- 1991-06-01 CN CN91104368A patent/CN1075113C/zh not_active Expired - Lifetime
- 1991-06-01 AP APAP/P/1991/000270A patent/AP207A/en active
- 1991-10-11 PH PH43285A patent/PH30761A/en unknown
-
1992
- 1992-10-01 HR HRP-951/91A patent/HRP920771B1/xx not_active IP Right Cessation
- 1992-11-24 NO NO19924528A patent/NO322962B1/no not_active IP Right Cessation
- 1992-11-26 BG BG97123A patent/BG61165B1/bg unknown
- 1992-11-30 FI FI925453A patent/FI114639B/fi active IP Right Grant
- 1992-11-30 KR KR1019920703049A patent/KR100212411B1/ko not_active Expired - Lifetime
-
1993
- 1993-07-30 LV LVP-93-1005A patent/LV10292B/en unknown
- 1993-12-30 LT LTIP1736A patent/LT4020B/lt not_active IP Right Cessation
-
1997
- 1997-05-08 HK HK62497A patent/HK62497A/en not_active IP Right Cessation
- 1997-05-30 GR GR970401262T patent/GR3023618T3/el unknown
-
2000
- 2000-11-20 CN CN00130975A patent/CN1326782A/zh active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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