ES2100861T3 - Composiciones farmaceuticas para la inhibicion de la reaccion de maillard. - Google Patents

Composiciones farmaceuticas para la inhibicion de la reaccion de maillard.

Info

Publication number
ES2100861T3
ES2100861T3 ES90122096T ES90122096T ES2100861T3 ES 2100861 T3 ES2100861 T3 ES 2100861T3 ES 90122096 T ES90122096 T ES 90122096T ES 90122096 T ES90122096 T ES 90122096T ES 2100861 T3 ES2100861 T3 ES 2100861T3
Authority
ES
Spain
Prior art keywords
chem
hydrogen
formula
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90122096T
Other languages
English (en)
Inventor
Jun Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2100861T3 publication Critical patent/ES2100861T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE PRESENTAN COMPOSICIONES FARMACEUTICAS QUE ESTAN COMPUESTAS, EN MEZCLA CON UN CATALIZADOR, DE UN COMPUESTO DE; A) LA FORMULA (I) O UNA SAL DE ESTE ACEPTABLE FARMACEUTICAMENTE: EN LA QUE R SUB 1 Y R SUB 2 SON CADA UNO HIDROGENO, METILO, TRIFLUOROMETILO, CARBOXI, METOXICARBONIL O ETOXICARBONIL, Y R SUB 3 ES HIDROGENO O HIDROXI; B) LA FORMULA (I) O UNA SAL DE ESTE FARMACEUTICAMENTE ACEPTABLE: EN LA QUE R SUB 1, R SUB 2 Y R SUB 3 SON COMO SE HA DEFINIDO; C) LA FORMULA (III) O UNA SAL DE ESTE FARMACEUTICAMENTE ACEPTABLE: EN LA QUE R SUB 4 Y R SUB 5 SON CADA UNO HIDROGENO O FORMAN, CON LA INCORPORACION DE ATOMOS DE CARBONO C SUB 1 Y C SUB 2, UN ANILLO DE [2.1-B] PIRIDINA CONDENSADA SUSTITUIDA OPCIONALMENTE CON UN GRUPO HIDROXILO O CARBOXILO, Y R SUB 6 ES HIDROGENO O HIDROXI; O (D) LA FORMULA (IV) O UNA SAL DE ESTE FARMACEUTICAMENTE ACEPTABLE: EN LA QUE R SUB 4, R SUB 5 Y R SUB 6 SON COMO SE HA DEFINIDO. LAS COMPOSICIONES SE UTILIZAN PARA INHIBIR LA REACCION DE MAILLARD EN EL CUERPO HUMANO, LA REACCION QUE PUEDE SER CAUSANTE DEL DESARROLLO DE COMPLICACIONES DIABETICAS Y MOLESTIAS ASOCIADAS A LA EDAD. TAMBIEN SE PRESENTAN LOS METODOS DE TRATAMIENTOS Y LA PROFILAXIS DE ESTAS COMPLICACIONES Y DESORDENES.
ES90122096T 1989-11-20 1990-11-19 Composiciones farmaceuticas para la inhibicion de la reaccion de maillard. Expired - Lifetime ES2100861T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1301413A JPH03161441A (ja) 1989-11-20 1989-11-20 メイラード反応阻害剤

Publications (1)

Publication Number Publication Date
ES2100861T3 true ES2100861T3 (es) 1997-07-01

Family

ID=17896581

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90122096T Expired - Lifetime ES2100861T3 (es) 1989-11-20 1990-11-19 Composiciones farmaceuticas para la inhibicion de la reaccion de maillard.

Country Status (7)

Country Link
EP (1) EP0433679B1 (es)
JP (1) JPH03161441A (es)
KR (1) KR910009665A (es)
AT (1) ATE152352T1 (es)
CA (1) CA2029421A1 (es)
DE (1) DE69030616T2 (es)
ES (1) ES2100861T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE220327T1 (de) 1992-09-29 2002-07-15 Inhale Therapeutic Syst Pulmonale abgabe von aktiven fragmenten des parathormons
ES2218543T3 (es) 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
GB2288732B (en) * 1994-04-13 1998-04-29 Quadrant Holdings Cambridge Pharmaceutical compositions
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
JP3988838B2 (ja) * 1996-05-29 2007-10-10 日本製粉株式会社 化粧料
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
CA2339879C (en) 1998-08-24 2011-11-15 Toshio Miyata Carbonyl-stress improving agent and peritoneal dialysate
FR2797443B1 (fr) * 1999-08-13 2003-10-31 Lafon Labor Procede de prepartion de quinoleine-5,8-diones
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7368102B2 (en) 2001-12-19 2008-05-06 Nektar Therapeutics Pulmonary delivery of aminoglycosides
MXPA05004528A (es) 2002-11-01 2005-07-26 Glaxosmithkline Biolog Sa Composicion inmunogenica.
FR2864535B1 (fr) * 2003-12-24 2006-12-22 Merck Sante Sas Derives acides de quinoline et leurs applications en therapeutique
JP4739705B2 (ja) * 2004-07-21 2011-08-03 ロート製薬株式会社 内服用組成物
JP4971403B2 (ja) * 2009-09-25 2012-07-11 パナソニック株式会社 除毛機
JP4894902B2 (ja) * 2009-09-25 2012-03-14 パナソニック電工株式会社 除毛機
CN108558906A (zh) * 2018-05-21 2018-09-21 日照市普达医药科技有限公司 一种治疗白内障药物苯并吩噁嗪类化合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359455A (en) * 1979-10-30 1982-11-16 Sunstar Hamigaki Kabushiki Kaisha Diagnostic test composition for dental caries activity
IN164557B (es) * 1986-08-27 1989-04-08 Hoechst Ag
JPH01211595A (ja) * 1988-02-18 1989-08-24 Kikkoman Corp 新規N−アセチル−β−D−グルコサミン誘導体、その製法及びN−アセチル−β−D−グルコサミニダーゼ活性測定用試薬への利用
US5112739A (en) * 1988-08-02 1992-05-12 Polaroid Corporation Enzyme controlled release system

Also Published As

Publication number Publication date
JPH03161441A (ja) 1991-07-11
KR910009665A (ko) 1991-06-28
DE69030616D1 (de) 1997-06-05
DE69030616T2 (de) 1997-12-11
ATE152352T1 (de) 1997-05-15
EP0433679B1 (en) 1997-05-02
EP0433679A2 (en) 1991-06-26
CA2029421A1 (en) 1991-05-21
EP0433679A3 (en) 1992-03-04

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