ES2101077T3 - Procedimiento para la inactivacion de priones. - Google Patents

Procedimiento para la inactivacion de priones.

Info

Publication number
ES2101077T3
ES2101077T3 ES92890128T ES92890128T ES2101077T3 ES 2101077 T3 ES2101077 T3 ES 2101077T3 ES 92890128 T ES92890128 T ES 92890128T ES 92890128 T ES92890128 T ES 92890128T ES 2101077 T3 ES2101077 T3 ES 2101077T3
Authority
ES
Spain
Prior art keywords
biological
prions
sodium
inactivation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92890128T
Other languages
English (en)
Other versions
ES2101077T5 (es
Inventor
Herwig Reichl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamosan Erzeugung Pharmazeutischer Grundstoffe GmbH
Original Assignee
Hamosan Erzeugung Pharmazeutischer Grundstoffe GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3517550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2101077(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hamosan Erzeugung Pharmazeutischer Grundstoffe GmbH filed Critical Hamosan Erzeugung Pharmazeutischer Grundstoffe GmbH
Application granted granted Critical
Publication of ES2101077T3 publication Critical patent/ES2101077T3/es
Publication of ES2101077T5 publication Critical patent/ES2101077T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood
    • Y10S530/83Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Harvester Elements (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Peptides Or Proteins (AREA)
  • Storage Of Fruits Or Vegetables (AREA)
  • Led Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DEBEN ELIMINAR PRIONES, VIRUS Y OTROS AGENTES INFECCIOSOS, QUE ESTAN PRESENTES EN MATERIALES BIOLOGICOS O BIOGENOS, POR EJEMPLO, EN UN PLASMA O SUERO, DEL CUAL SE OBTIENE LA ALBUMINA, SIN AFECTAR EL MATERIAL BIOLOGICO. PARA ELLO, DE ACUERDO CON LA INVENCION, SE TRATA EL MATERIAL BIOLOGICO O BIOGENO CON UN REACTIVO CAOTROPO, POR EJEMPLO, CON UREA O TIOCIANATO SODICO, APROXIMADAMENTE 18 HORAS. PREVIAMENTE SE PUEDE AÑADIR UN DETERGENTE, POR EJEMPLO, LAURILSULFATO SODICO, ASI COMO ALCOHOL METILICO O ETILICO Y CALENTARSE LA SOLUCION DURANTE 30 MINUTOS A UNOS 70 (GRADOS) C. DESPUES DEL ENFRIAMIENTO Y ACIDIFICADO SE PUEDEN SEPARAR LAS GLOBULINAS.
ES92890128T 1991-08-19 1992-05-26 Procedimiento para la inactivacion de priones. Expired - Lifetime ES2101077T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0162991A AT408191B (de) 1991-08-19 1991-08-19 Verfahren zur inaktivierung von prionen

Publications (2)

Publication Number Publication Date
ES2101077T3 true ES2101077T3 (es) 1997-07-01
ES2101077T5 ES2101077T5 (es) 2002-02-01

Family

ID=3517550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92890128T Expired - Lifetime ES2101077T5 (es) 1991-08-19 1992-05-26 Procedimiento para la inactivacion de priones.

Country Status (7)

Country Link
US (1) US5633349A (es)
EP (1) EP0530173B2 (es)
AT (2) AT408191B (es)
DE (1) DE59208095D1 (es)
DK (1) DK0530173T4 (es)
ES (1) ES2101077T5 (es)
GR (1) GR3023206T3 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP940645A2 (en) * 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
EP0888131B1 (fr) 1996-03-15 2002-04-03 Aventis Pasteur Procede pour eliminer les agents transmissibles non conventionnels d'une solution proteique
FR2750887B1 (fr) * 1996-07-09 1998-10-23 Imedex Procede d'elimination des agents transmissibles non conventionnels (atnc) d'une solution proteique
FR2746030B1 (fr) * 1996-03-15 1998-04-17 Procede pour eliminer les agents transmissibles non conventionnels (atnc) d'une solution d'albumine
US20060008494A1 (en) * 1997-02-21 2006-01-12 The Regents Of The University Of California Complete inactivation of infectious proteins
US6720355B2 (en) * 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
EP1801591B1 (en) 1997-08-04 2016-12-28 Advanced Life Science Institute, Inc. Methods for detection or measurement of viruses
AUPP276098A0 (en) * 1998-04-01 1998-04-30 Nokuta Pty Ltd A method for treating gelatine
ES2284250T3 (es) 1998-04-21 2007-11-01 Infectio Recherche Inc. Formulaciones para la prevencion o el tratamiento de enfermedades que afectan a la membrana mucosa o la piel, o para la prevencion del embarazo.
AT407485B (de) * 1999-04-14 2001-03-26 Haemosan Erzeugung Pharmazeuti Neue medizinische verwendung von alpha1-saurem glykoprotein
JP2002542775A (ja) * 1999-04-26 2002-12-17 ユニヴェルシテ ドゥ モントリオール プリオン滅菌プロセスを評価するための生物学的指標
BR0011055A (pt) * 1999-06-01 2002-05-21 Univ California Método de esterilização
US6437102B1 (en) 1999-11-24 2002-08-20 Bayer Corporation Method of separating prions from biological materials
PT1251737E (pt) * 2000-01-31 2005-08-31 Univ California Composicoes tratadas para inactivar proteinas infecciosas
US6458322B1 (en) * 2000-09-08 2002-10-01 Bioavailability Systems, Llc Method for simplified shipping of clinical specimens and optional direct analysis
US7465295B2 (en) * 2000-10-20 2008-12-16 Bergeron Michel G Applicator for the delivery of topical formulations into mucosal cavities
US20030050276A1 (en) * 2001-08-15 2003-03-13 Cunanan Crystal M. Treatment of tissue, instruments and work surfaces to remove infectious agents
IES20010042A2 (en) * 2001-01-19 2002-12-11 Enfer Technology Ltd Test for transmissible spongiform encephalopathies
US7577577B2 (en) * 2001-01-31 2009-08-18 Dell Products L.P. Pull to customer order demand fulfillment system and method
AUPR293801A0 (en) 2001-02-07 2001-03-01 Novapharm Research (Australia) Pty Ltd Prion disinfection
US6613505B2 (en) 2001-04-12 2003-09-02 Bioresource International, Inc. Composition and method for destruction of infetious prion proteins
US7521479B2 (en) * 2001-04-16 2009-04-21 Panacea Pharmaceuticals, Inc. Methods of treating prion disease in mammals
AU2002211544A1 (en) 2001-05-08 2002-11-18 Serologicals Royalty Company Process for inactivating prions in lipoproteins
AU2002351353A1 (en) * 2001-12-19 2003-09-02 Genentech, Inc. Stabilizing polypeptides which have been exposed to urea
DE10222234A1 (de) * 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Kontroll- und Kalibrationsmaterial für Blutgerinnungstests
CA2487072A1 (en) * 2002-05-23 2003-12-04 Ortho-Clinical Diagnostics, Inc. Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration
DE10224273B4 (de) * 2002-05-31 2004-07-15 Fujitsu Siemens Computers Gmbh Kühlanordnung für einen Tower-PC
US20050032913A1 (en) * 2003-08-08 2005-02-10 Steris Inc. Decontamination of prion-contaminated surfaces with phenols
FR2867388B1 (fr) * 2004-03-12 2006-06-23 Agronomique Inst Nat Rech Compositions et methodes pour la destruction de proteines prion infectieuses.
ITMI20040891A1 (it) * 2004-05-04 2004-08-04 Ibsa Inst Biochimique Sa Nuovo metodo per la partizione ed inattivazione di contaminanti virali e prionici
US20090118470A1 (en) * 2005-08-25 2009-05-07 Detlev Riesner Prion Inactivation
US20070231202A1 (en) * 2006-03-31 2007-10-04 Roberts Charles G method and system for prion inactivation
US8293174B2 (en) 2007-10-17 2012-10-23 American Sterilizer Company Prion deactivating composition and methods of using same
EP4403193A3 (en) * 2017-01-30 2025-01-22 Regeneron Pharmaceuticals, Inc. Method for reducing bioburden in chromatography

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623717A (en) * 1980-03-05 1986-11-18 Miles Laboratories, Inc. Pasteurized therapeutically active protein compositions
DE3173208D1 (en) * 1980-10-06 1986-01-23 Edward Shanbrom Method of reducing undesirable activities of biological and pharmaceutical products
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
AT390001B (de) * 1984-09-28 1990-03-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern
DE3618817A1 (de) * 1986-06-04 1987-12-10 Behringwerke Ag Verfahren zur gewinnung aktiver proteine aus einer biologisch inaktiven form
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
JPH0774161B2 (ja) * 1986-12-29 1995-08-09 財団法人化学及血清療法研究所 毒素のトキソイド化法
US5177191A (en) * 1987-12-21 1993-01-05 Miles, Inc. Gel filtration of factor VIII
GB8821049D0 (en) * 1988-09-08 1988-10-05 Health Lab Service Board Method & composition for treatment & prevention of viral infections
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
CA2007545A1 (en) * 1989-01-13 1990-07-13 Yahiro Uemura Production method for protein-containing composition
DE69027187T2 (de) * 1989-06-15 1996-10-31 Rorer Int Overseas Verfahren zur inaktivierung von viren in mit viren verunreinigten pharmazeutischen zusammensetzungen
US5071650A (en) * 1990-06-04 1991-12-10 Miles Inc. Use of intermediate length alcohols as virucidal agents in solutions of biologically active proteins

Also Published As

Publication number Publication date
EP0530173B1 (de) 1997-03-05
US5633349A (en) 1997-05-27
EP0530173A2 (de) 1993-03-03
ES2101077T5 (es) 2002-02-01
ATE149355T1 (de) 1997-03-15
DK0530173T4 (da) 2001-12-03
EP0530173A3 (en) 1993-05-19
DK0530173T3 (da) 1997-04-21
DE59208095D1 (de) 1997-04-10
AT408191B (de) 2001-09-25
ATA162991A (de) 1993-05-15
EP0530173B2 (de) 2001-08-22
GR3023206T3 (en) 1997-07-30

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