ES2113347T3 - Procedimiento para la desactivacion de virus en sangre y en productos de sangre. - Google Patents

Procedimiento para la desactivacion de virus en sangre y en productos de sangre.

Info

Publication number
ES2113347T3
ES2113347T3 ES90913337T ES90913337T ES2113347T3 ES 2113347 T3 ES2113347 T3 ES 2113347T3 ES 90913337 T ES90913337 T ES 90913337T ES 90913337 T ES90913337 T ES 90913337T ES 2113347 T3 ES2113347 T3 ES 2113347T3
Authority
ES
Spain
Prior art keywords
blood
dyes
viruses
deactivation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90913337T
Other languages
English (en)
Other versions
ES2113347T5 (es
Inventor
Harald Mohr
Bernd Lambrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BLUTSPENDED LANDESVERBANDE DES
Original Assignee
BLUTSPENDED LANDESVERBANDE DES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6389298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2113347(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BLUTSPENDED LANDESVERBANDE DES filed Critical BLUTSPENDED LANDESVERBANDE DES
Application granted granted Critical
Publication of ES2113347T3 publication Critical patent/ES2113347T3/es
Publication of ES2113347T5 publication Critical patent/ES2113347T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA INACTIVAR VIRUS EN LA SANGRE Y EN PRODUCTOS SANGUINEOS EN QUE TINTES DE FENOTIAZINA SE AÑADEN A LAS SOLUCIONES O SUSPENSIONES, QUE SE IRRADIAN DESPUES CON LUZ. EL USO DE UNA CONCENTRACION MUY PEQUEÑA DE TINTES DE FENOTIAZINA EVITA QUE SE PRODUZCAN EFECTOS ADVERSOS EN LAS PROTEINAS DEL PLASMA. LA INACTIVACION SE EFECTUA MEDIANTE LA IRRADIACION INMEDIATA DE LA BOLSITA CON SANGRE. DESPUES DE LA IRRADIACION, LOS TINTES SE PUEDEN VOLVER A SEPARAR DE LA SANGRE HACIENDO PASAR LA SANGRE POR AGENTES ABSORBENTES.
ES90913337T 1989-09-13 1990-09-08 Procedimiento para la desactivacion de virus en sangre y en productos de sangre. Expired - Lifetime ES2113347T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3930510A DE3930510A1 (de) 1989-09-13 1989-09-13 Verfahren zur inaktivierung von viren in blut und blutprodukten

Publications (2)

Publication Number Publication Date
ES2113347T3 true ES2113347T3 (es) 1998-05-01
ES2113347T5 ES2113347T5 (es) 2002-09-16

Family

ID=6389298

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90913337T Expired - Lifetime ES2113347T5 (es) 1989-09-13 1990-09-08 Procedimiento para la desactivacion de virus en sangre y en productos de sangre.

Country Status (14)

Country Link
EP (2) EP0593098A3 (es)
JP (1) JP2965695B2 (es)
AT (1) ATE161681T1 (es)
AU (1) AU635068B2 (es)
CA (1) CA2065842C (es)
CS (1) CS76692A3 (es)
DE (3) DE3930510A1 (es)
DK (1) DK0491757T4 (es)
ES (1) ES2113347T5 (es)
FI (1) FI99192C (es)
HU (1) HU215131B (es)
NO (1) NO300911B1 (es)
RU (1) RU2036235C1 (es)
WO (1) WO1991003933A1 (es)

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US6348309B1 (en) * 1989-09-13 2002-02-19 Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
DE9102709U1 (de) * 1991-03-07 1991-05-23 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe Blutbeutelanordnung
WO1996014740A1 (en) 1992-03-02 1996-05-23 Cerus Corporation Synthetic media for blood components
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
US6207107B1 (en) * 1992-10-05 2001-03-27 Baxter International Inc. Steam sterilizable system for inactivating viral contaminants in body fluids
ZA944488B (en) * 1993-06-23 1995-02-15 New York Blood Center Inc System for viral inactivation of blood
US5712085A (en) 1993-06-28 1998-01-27 Cerus Corporation 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
WO1995018665A1 (en) * 1994-01-10 1995-07-13 Hemasure, Inc. Device and process for removing leukocytes and viral inactivating agents from blood
US5639376A (en) * 1994-01-10 1997-06-17 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
DE4444045C2 (de) * 1994-12-10 1997-04-17 Behringwerke Ag Verfahren zur Inaktivierung von Viren mit Hilfe von Acridin oder Acridinderivaten
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
AT406778B (de) * 1996-04-09 2000-09-25 Immuno Ag Verfahren zur desintegration von nucleinsäuren und herstellung von qualitätsgesicherten biologischen produkten
EP0906563A1 (en) * 1996-06-17 1999-04-07 Mercury Diagnostics Inc. Electrochemical test device and related methods
US5922278A (en) * 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
ES2210846T3 (es) * 1997-11-20 2004-07-01 Cerus Corporation Nuevos psoralenos para inactivar agentes patogenos.
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7049110B2 (en) 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7498156B2 (en) 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6610436B1 (en) 1998-09-11 2003-08-26 Gore Enterprise Holdings Catalytic coatings and fuel cell electrodes and membrane electrode assemblies made therefrom
DE19904088A1 (de) 1999-02-02 2000-09-07 Fressenius Hemocare Gmbh Schlauchset für einen Zellseparator zum Separieren von Blut in seine Komponenten und Verfahren zum Separieren von Blut in seine Komponenten
DE19914850A1 (de) * 1999-04-01 2000-10-05 Gerhard Saalmann Vorrichtung und Verfahren zur Inaktivierung von Viren in biologischen Flüssigkeiten
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
RU2200009C2 (ru) * 1999-08-04 2003-03-10 Григорьянц Рубен Исаакович Лечение синдрома приобретенного иммунодефицита (спид) способом фотосенсибилизации
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US7648699B2 (en) 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7985588B2 (en) 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
DE10031851B4 (de) * 2000-07-04 2005-10-13 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Photodynamische Behandlung und UV-B-Bestrahlung einer Thrombozyten-Suspension
EP1469891B1 (en) * 2002-02-01 2009-04-15 CaridianBCT Biotechnologies, LLC Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
RU2223124C1 (ru) * 2003-03-20 2004-02-10 Федченко Петр Петрович Способ инактивации вируса спида
RU2357770C1 (ru) * 2007-09-27 2009-06-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Способ фотоинактивации вируса гриппа а птиц подтипа h5n1
EA032842B1 (ru) * 2014-05-23 2019-07-31 Овик Леонардович МКРТЧЯН Способ инактивации рнк и днк содержащих вирусов на медицинском инструментарии и установка для его осуществления

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Also Published As

Publication number Publication date
AU635068B2 (en) 1993-03-11
EP0491757B1 (de) 1998-01-07
CA2065842C (en) 1999-12-21
EP0593098A2 (de) 1994-04-20
ES2113347T5 (es) 2002-09-16
DE122008000026I1 (de) 2008-08-21
HU215131B (hu) 1998-09-28
DK0491757T4 (da) 2002-04-22
CS76692A3 (en) 1992-08-12
AU6339190A (en) 1991-04-18
WO1991003933A1 (de) 1991-04-04
EP0593098A3 (de) 1994-04-27
JP2965695B2 (ja) 1999-10-18
JPH05500366A (ja) 1993-01-28
FI920981A0 (fi) 1992-03-05
HU9200627D0 (en) 1992-05-28
NO300911B1 (no) 1997-08-18
FI99192C (fi) 1997-10-27
DK0491757T3 (da) 1998-09-07
DE122008000026I2 (de) 2011-05-05
ATE161681T1 (de) 1998-01-15
DE59010793D1 (de) 1998-02-12
CA2065842A1 (en) 1991-03-14
NO920834D0 (no) 1992-03-03
EP0491757A1 (de) 1992-07-01
RU2036235C1 (ru) 1995-05-27
NO920834L (no) 1992-03-03
EP0491757B2 (de) 2002-01-09
FI99192B (fi) 1997-07-15
DE3930510A1 (de) 1991-03-21
HUT60142A (en) 1992-08-28

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