ES2101164T3 - Composiciones farmaceuticas orales para el suministro especifico al colon. - Google Patents
Composiciones farmaceuticas orales para el suministro especifico al colon.Info
- Publication number
- ES2101164T3 ES2101164T3 ES93108658T ES93108658T ES2101164T3 ES 2101164 T3 ES2101164 T3 ES 2101164T3 ES 93108658 T ES93108658 T ES 93108658T ES 93108658 T ES93108658 T ES 93108658T ES 2101164 T3 ES2101164 T3 ES 2101164T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- colon
- oral pharmaceutical
- nucleus
- specific supply
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000001072 colon Anatomy 0.000 title 1
- 239000008203 oral pharmaceutical composition Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 2
- 238000004090 dissolution Methods 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000010339 dilation Effects 0.000 abstract 1
- 230000003628 erosive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS, DE ADMINISTRACION POR VIA ORAL, CONSTITUIDAS POR: A) UN NUCLEO QUE CONTIENE EL PRINCIPIO ACTIVO DE UNA MEZCLA DE PRINCIPIOS ACTIVOS, OPCIONALMENTE COMBINADOS CON EXCIPIENTES; B) UNA CAPA INTERMEDIA DE REVESTIMIENTO DEL CITADO NUCLEO, QUE PUEDE RETRASAR EL PRINCIPIO ACTIVO CONTENIDO EN EL NUCLEO DURANTE EL TIEMPO PROGRAMADO, INDEPENDIENTEMENTE DEL PH; C) OTRA CAPA EXTERIOR, CUYA DISOLUCION ACTIVA EL PROCESO DE DILATACION/DISOLUCION/EROSION DE LA CAPA INTERMEDIA DE REVESTIMIENTO DEL PUNTO B).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI921347A IT1260505B (it) | 1992-06-01 | 1992-06-01 | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2101164T3 true ES2101164T3 (es) | 1997-07-01 |
| ES2101164T5 ES2101164T5 (es) | 2001-02-01 |
Family
ID=11363431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93108658T Expired - Lifetime ES2101164T5 (es) | 1992-06-01 | 1993-05-28 | Composiciones farmaceuticas orales para el suministro especifico al colon. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0572942B2 (es) |
| AT (1) | ATE151285T1 (es) |
| DE (1) | DE69309540T3 (es) |
| DK (1) | DK0572942T4 (es) |
| ES (1) | ES2101164T5 (es) |
| GR (2) | GR3023605T3 (es) |
| HU (1) | HUT75158A (es) |
| IT (1) | IT1260505B (es) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6764697B1 (en) | 1991-06-27 | 2004-07-20 | Alza Corporation | System for delaying drug delivery up to seven hours |
| US5686105A (en) * | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| US5436011A (en) * | 1993-04-16 | 1995-07-25 | Bristol-Myers Squibb Company | Solid pharmaceutical dosage form and a method for reducing abrasion |
| ES2068762B1 (es) * | 1993-07-21 | 1995-12-01 | Lipotec Sa | Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion. |
| US5482718A (en) * | 1994-03-23 | 1996-01-09 | Hoffmann-La Roche Inc. | Colon-targeted delivery system |
| US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
| US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
| GB9620709D0 (en) * | 1996-10-04 | 1996-11-20 | Danbiosyst Uk | Colonic delivery of weak acid drugs |
| US5788987A (en) | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| US5891474A (en) * | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
| NL1009107C2 (nl) | 1997-11-12 | 1999-06-15 | Banner Pharmacaps Inc | Gelatine-uitspreidende doos met meervoudige, aanpasbare poortklep en meerlagig zacht gel. |
| US6531152B1 (en) | 1998-09-30 | 2003-03-11 | Dexcel Pharma Technologies Ltd. | Immediate release gastrointestinal drug delivery system |
| UA74141C2 (uk) | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| ATE404172T1 (de) | 1998-12-30 | 2008-08-15 | Dexcel Ltd | Dispergierbares konzentrat zur verabreichung von cyclosporin |
| US6632451B2 (en) | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| AP1748A (en) | 2001-03-13 | 2007-06-11 | Penwest Pharmaceuticals Co | Chronotherapeutic dosage forms. |
| FR2830446B1 (fr) * | 2001-10-09 | 2004-02-06 | Univ Pasteur | Composition pharmaceutique destinee a liberer une substance active au niveau du colon |
| CA2501324A1 (en) * | 2002-10-30 | 2004-05-21 | Pharmacia Corporation | Oral extended release tablets and methods of making and using the same |
| CU23334A1 (es) * | 2003-03-20 | 2008-12-24 | Inst Finlay | Vacuna de vibrio cholerae inactivada en tabletas |
| US8389008B2 (en) | 2003-09-19 | 2013-03-05 | Penwest Pharmaceuticals Co. | Delayed release dosage forms |
| GB2411355B (en) | 2004-02-27 | 2006-02-22 | Niche Generics Ltd | Pharmaceutical composition |
| ITMI20041295A1 (it) | 2004-06-25 | 2004-09-25 | Cosmo Spa | Composizioni farmaceutiche antimicrobiche orali |
| EP1754471A1 (de) * | 2005-08-18 | 2007-02-21 | ORAMON-Arzneimittel GmbH & Co. KG | Verwendung einer quellbaren Zwischenschicht zur Steuerung des Freisetzungsprofils einer festen Arzneimittelformulierung zur peroralen Anwendung und diese enthaltende Arzneimittelformulierung |
| GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
| GB0714030D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| GB0714029D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
| WO2010000783A1 (de) * | 2008-07-02 | 2010-01-07 | Basf Se | Verfahren zum beschichten von tabletten |
| IT1393244B1 (it) | 2008-07-18 | 2012-04-12 | Universita' Degli Studi Di Milano | Sistema per il rilascio al colon di farmaci suscettibili di degradazione enzimatica e/o scarsamente assorbiti nel tratto gastrointestinale |
| CA2749278A1 (en) | 2009-01-14 | 2010-07-22 | Novacta Biosystems Limited | Deoxyactagardine derivatives |
| CN102388060B (zh) | 2009-02-04 | 2014-09-10 | 诺瓦克塔生物系统有限公司 | 阿肽加定衍生物 |
| WO2015161139A1 (en) | 2014-04-16 | 2015-10-22 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| GB201001688D0 (en) | 2010-02-02 | 2010-03-17 | Novacta Biosystems Ltd | Compounds |
| WO2012013495A1 (en) | 2010-07-29 | 2012-02-02 | Cosmo Technologies Ltd. | Pharmaceutical and/or dietary compositions based on short chain fatty acids |
| GB201013513D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Formulations |
| US20140227293A1 (en) | 2011-06-30 | 2014-08-14 | Trustees Of Boston University | Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1) |
| CA2901284A1 (en) | 2013-04-05 | 2014-10-09 | Polichem Sa | Use of pidotimod to treat irritable bowel syndrome |
| EP3089737B1 (en) | 2013-12-31 | 2021-11-03 | Rapamycin Holdings, LLC | Oral rapamycin nanoparticle preparations and use |
| CN105943505A (zh) * | 2016-05-26 | 2016-09-21 | 杭州百诚医药科技股份有限公司 | 一种匹多莫德药物组合物及其制备方法 |
| JP2022544239A (ja) | 2019-08-12 | 2022-10-17 | マサチューセッツ インスティテュート オブ テクノロジー | 治療薬の投与のための物品及び方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
| IT1230576B (it) | 1988-10-20 | 1991-10-28 | Angeli Inst Spa | Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon |
| US5032406A (en) † | 1989-02-21 | 1991-07-16 | Norwich Eaton Pharmaceuticals, Inc. | Dual-action tablet |
| PH27186A (en) * | 1989-09-07 | 1993-04-16 | Ciba Geigy Ag | Double-coated granules of disodium pamidronate |
| DK469989D0 (da) † | 1989-09-22 | 1989-09-22 | Bukh Meditec | Farmaceutisk praeparat |
| IT1246382B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
-
1992
- 1992-06-01 IT ITMI921347A patent/IT1260505B/it active IP Right Grant
-
1993
- 1993-05-28 DK DK93108658T patent/DK0572942T4/da active
- 1993-05-28 HU HU9301577A patent/HUT75158A/hu unknown
- 1993-05-28 EP EP93108658A patent/EP0572942B2/en not_active Expired - Lifetime
- 1993-05-28 ES ES93108658T patent/ES2101164T5/es not_active Expired - Lifetime
- 1993-05-28 DE DE69309540T patent/DE69309540T3/de not_active Expired - Lifetime
- 1993-05-28 AT AT93108658T patent/ATE151285T1/de active
-
1997
- 1997-05-30 GR GR970401249T patent/GR3023605T3/el unknown
-
2001
- 2001-02-14 GR GR20010400245T patent/GR3035415T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE151285T1 (de) | 1997-04-15 |
| DK0572942T4 (da) | 2001-01-22 |
| ES2101164T5 (es) | 2001-02-01 |
| EP0572942A3 (en) | 1994-08-24 |
| DE69309540D1 (de) | 1997-05-15 |
| GR3035415T3 (en) | 2001-05-31 |
| EP0572942A2 (en) | 1993-12-08 |
| GR3023605T3 (en) | 1997-08-29 |
| HU9301577D0 (en) | 1993-09-28 |
| EP0572942B1 (en) | 1997-04-09 |
| EP0572942B2 (en) | 2000-11-29 |
| DK0572942T3 (da) | 1997-10-20 |
| HUT75158A (en) | 1997-04-28 |
| DE69309540T2 (de) | 1997-09-04 |
| DE69309540T3 (de) | 2001-03-15 |
| IT1260505B (it) | 1996-04-09 |
| ITMI921347A0 (it) | 1992-06-01 |
| ITMI921347A1 (it) | 1993-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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