ES2103136T3 - Kit de ensayo. - Google Patents
Kit de ensayo.Info
- Publication number
- ES2103136T3 ES2103136T3 ES94927577T ES94927577T ES2103136T3 ES 2103136 T3 ES2103136 T3 ES 2103136T3 ES 94927577 T ES94927577 T ES 94927577T ES 94927577 T ES94927577 T ES 94927577T ES 2103136 T3 ES2103136 T3 ES 2103136T3
- Authority
- ES
- Spain
- Prior art keywords
- link
- suin
- competitor
- test
- test kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Sampling And Sample Adjustment (AREA)
- Fishing Rods (AREA)
- Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
- Saccharide Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
- Sanitary Device For Flush Toilet (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE PROPORCIONA UN NUEVO METODO DE MEDIDA DE LOS NIVELES DE SANGRE DE COMPUESTOS FARMACEUTICOS DE ENLACE DE INMUNOFILINA, POR EJEMPLO, CICLOSPORINAS, RAPAMICINAS, Y FK506, QUE COMPRENDE EL NUEVO PASO DE DESPLAZAR EL FARMACO DE SU INMUNOFILINA MEDIANTE LA UTILIZACION DE UN COMPETIDOR DE ENLACE, ELIMINANDO DE ESTA MANERA LA NECESIDAD DE UN PASO DE EXTRACCION Y AUMENTANDO LA SIMPLICIDAD Y EXACTITUD DEL ENSAYO. SE PROPORCIONAN TAMBIEN CONJUNTOS DE ENSAYO QUE COMPRENDEN UN COMPETIDOR Y UN RECEPTOR DE ENLACE, POR EJEMPLO, UN ANTICUERPO MONOCLONAL, QUE ENLAZA CON EL FARMACO PERO NO SIGNIFICATIVAMENTE CON EL COMPETIDOR DE ENLACE, COMO SON NUEVAS UTILIZACIONES DE COMPUESTOS DE ENLACE DE INMUNOFILINA COMO COMPETIDORES DE ENLACE EN TALES ENSAYOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939318612A GB9318612D0 (en) | 1993-09-08 | 1993-09-08 | An assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2103136T3 true ES2103136T3 (es) | 1997-08-16 |
Family
ID=10741695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94927577T Expired - Lifetime ES2103136T3 (es) | 1993-09-08 | 1994-09-07 | Kit de ensayo. |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0717850B1 (es) |
| JP (1) | JP2892503B2 (es) |
| KR (1) | KR100313841B1 (es) |
| CN (1) | CN1088196C (es) |
| AT (1) | ATE153769T1 (es) |
| AU (1) | AU680946B2 (es) |
| BR (1) | BR9407422A (es) |
| CA (1) | CA2169162C (es) |
| CZ (1) | CZ289434B6 (es) |
| DE (1) | DE69403484T2 (es) |
| DK (1) | DK0717850T3 (es) |
| ES (1) | ES2103136T3 (es) |
| FI (1) | FI111035B (es) |
| GB (1) | GB9318612D0 (es) |
| GR (1) | GR3023578T3 (es) |
| HU (1) | HU218743B (es) |
| NO (1) | NO960924D0 (es) |
| NZ (1) | NZ273595A (es) |
| PL (1) | PL176727B1 (es) |
| RU (1) | RU2138052C1 (es) |
| SK (1) | SK281369B6 (es) |
| WO (1) | WO1995007468A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187757B1 (en) | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
| US5650288A (en) * | 1995-07-14 | 1997-07-22 | Macfarlane; Gordon D. | Immunophilin-bound immunosuppressant assay |
| WO1997033604A1 (en) * | 1996-03-12 | 1997-09-18 | Picower Institute For Medical Research | Treatment of hiv-infection by interfering with host cell cyclophilin receptor activity |
| US6106779A (en) * | 1997-10-02 | 2000-08-22 | Biosite Diagnostics, Inc. | Lysis chamber for use in an assay device |
| ATE264863T1 (de) | 1999-08-24 | 2004-05-15 | Ariad Gene Therapeutics Inc | 28-epirapaloge |
| US7067526B1 (en) | 1999-08-24 | 2006-06-27 | Ariad Gene Therapeutics, Inc. | 28-epirapalogs |
| AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| US7186518B2 (en) | 2003-11-21 | 2007-03-06 | Dade Behring Inc. | Method and composition useful for determining FK 506 |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| AU2006259348B2 (en) | 2005-06-17 | 2010-07-22 | Novartis Ag | Use of sanglifehrin in HCV |
| CN100434901C (zh) * | 2006-01-12 | 2008-11-19 | 上海交通大学 | 血红蛋白凝胶层析的教学试剂盒 |
| US7914999B2 (en) * | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
| US7790401B2 (en) * | 2007-08-06 | 2010-09-07 | Siemens Healthcare Diagnostics | Methods for detection of immunosuppressant drugs |
| US8921642B2 (en) | 2008-01-11 | 2014-12-30 | Massachusetts Eye And Ear Infirmary | Conditional-stop dimerizable caspase transgenic animals |
| US9658218B2 (en) | 2012-05-07 | 2017-05-23 | Siemens Healthcare Diagnostics Inc. | Determination of total analyte concentration |
| US9121859B2 (en) * | 2012-12-04 | 2015-09-01 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of FKBP-binding immunosuppressant drugs |
| EP3008192B1 (en) | 2013-06-11 | 2019-07-17 | Takara Bio USA, Inc. | Protein enriched microvesicles and methods of making and using the same |
| KR101760707B1 (ko) | 2015-01-05 | 2017-07-24 | 한림대학교 산학협력단 | 이종 알부민을 이용한 장기 이식 거부반응 검사용 키트 |
| CN104749009B (zh) * | 2015-03-30 | 2018-05-04 | 上海云泽生物科技有限公司 | 用于免疫分析的免疫抑制剂药物提取试剂 |
| CN104764883A (zh) * | 2015-03-31 | 2015-07-08 | 上海云泽生物科技有限公司 | 一种检测环孢霉素a浓度的免疫分析方法和试剂盒 |
| ES2992864T3 (en) * | 2018-11-02 | 2024-12-18 | Siemens Healthcare Diagnostics Inc | Binding competitors for use in macrophilin-binding pharmaceutical assays and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1490650A1 (ru) * | 1987-04-06 | 1989-06-30 | Институт биологической физики АН СССР | Способ количественного определени стероидных гормонов |
| DE3886265T2 (de) * | 1987-06-05 | 1994-04-28 | Fujisawa Pharmaceutical Co | Anti-FR-900506-Stoffe-Antikörper und höchstempfindliches Enzym-Immunoassay-Verfahren. |
| DE3884470T2 (de) * | 1987-06-17 | 1994-03-10 | Sandoz Ag | Cyclosporine und deren Benutzung als Arzneimittel. |
| US5322772A (en) * | 1991-04-09 | 1994-06-21 | Children's Research Institute | Rapamycin assay |
| WO1993025533A1 (en) * | 1992-06-05 | 1993-12-23 | Abbott Laboratories | Methods and reagents for the determination of immunosuppressive agents |
| GB9307491D0 (en) * | 1993-04-08 | 1993-06-02 | Sandoz Ltd | Organic compounds |
-
1993
- 1993-09-08 GB GB939318612A patent/GB9318612D0/en active Pending
-
1994
- 1994-09-07 DK DK94927577.0T patent/DK0717850T3/da active
- 1994-09-07 HU HU9600564A patent/HU218743B/hu not_active IP Right Cessation
- 1994-09-07 WO PCT/EP1994/002986 patent/WO1995007468A1/en not_active Ceased
- 1994-09-07 CZ CZ1996662A patent/CZ289434B6/cs not_active IP Right Cessation
- 1994-09-07 EP EP94927577A patent/EP0717850B1/en not_active Expired - Lifetime
- 1994-09-07 RU RU96107464A patent/RU2138052C1/ru not_active IP Right Cessation
- 1994-09-07 SK SK310-96A patent/SK281369B6/sk unknown
- 1994-09-07 PL PL94313392A patent/PL176727B1/pl unknown
- 1994-09-07 BR BR9407422A patent/BR9407422A/pt not_active Application Discontinuation
- 1994-09-07 CA CA002169162A patent/CA2169162C/en not_active Expired - Lifetime
- 1994-09-07 DE DE69403484T patent/DE69403484T2/de not_active Expired - Lifetime
- 1994-09-07 ES ES94927577T patent/ES2103136T3/es not_active Expired - Lifetime
- 1994-09-07 CN CN94193303A patent/CN1088196C/zh not_active Expired - Fee Related
- 1994-09-07 NZ NZ273595A patent/NZ273595A/en unknown
- 1994-09-07 KR KR1019960701107A patent/KR100313841B1/ko not_active Expired - Fee Related
- 1994-09-07 JP JP7508458A patent/JP2892503B2/ja not_active Expired - Lifetime
- 1994-09-07 AU AU76948/94A patent/AU680946B2/en not_active Ceased
- 1994-09-07 AT AT94927577T patent/ATE153769T1/de active
-
1996
- 1996-03-04 FI FI961004A patent/FI111035B/fi not_active IP Right Cessation
- 1996-03-07 NO NO960924A patent/NO960924D0/no unknown
-
1997
- 1997-05-29 GR GR970401194T patent/GR3023578T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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