ES2103803T3 - Ensayo inmunocromatografico y metodo para utilizar el mismo. - Google Patents

Ensayo inmunocromatografico y metodo para utilizar el mismo.

Info

Publication number
ES2103803T3
ES2103803T3 ES91904867T ES91904867T ES2103803T3 ES 2103803 T3 ES2103803 T3 ES 2103803T3 ES 91904867 T ES91904867 T ES 91904867T ES 91904867 T ES91904867 T ES 91904867T ES 2103803 T3 ES2103803 T3 ES 2103803T3
Authority
ES
Spain
Prior art keywords
tests
immunocromatographic
test
lat
latex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91904867T
Other languages
English (en)
Other versions
ES2103803T5 (es
Inventor
Eugene Fan
Dou-Mei Wang
Fon-Chiu Mia Chen
Gregg L Wilson
Michael W Milner
Ching Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pacific Biotech Inc
Original Assignee
Pacific Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23893251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2103803(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pacific Biotech Inc filed Critical Pacific Biotech Inc
Application granted granted Critical
Publication of ES2103803T3 publication Critical patent/ES2103803T3/es
Publication of ES2103803T5 publication Critical patent/ES2103803T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/814—Pregnancy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION EXPUESTA SE REFIERE AL CAMPO DE PRUEBAS DE UN SOLO PASO Y A LAS PRUEBAS DE AGLUTINACION DE LATEX ("LAT"), Y PROPORCIONA UN METODO PERFECCIONADO DE PREPARACION Y USO DE PRUEBAS DE INMUNIDAD DE UN PASO, ASI COMO DE METODOS PERFECCIONADOS DE PREPARACION DE PARTICULAS DE LATEX CUBIERTAS PARA UTILIZAR EN PRUEBAS DE DIAGNOSTICO Y, ESPECIALMENTE, EN PRUEBAS INMUNOCROMATOGRAFICAS.
ES91904867T 1990-02-08 1991-02-08 Metodo inmunocromatografico. Expired - Lifetime ES2103803T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US476788 1990-02-08
US07/476,788 US5096837A (en) 1990-02-08 1990-02-08 Immunochromatographic assay and method of using same

Publications (2)

Publication Number Publication Date
ES2103803T3 true ES2103803T3 (es) 1997-10-01
ES2103803T5 ES2103803T5 (es) 2007-12-16

Family

ID=23893251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91904867T Expired - Lifetime ES2103803T5 (es) 1990-02-08 1991-02-08 Metodo inmunocromatografico.

Country Status (10)

Country Link
US (1) US5096837A (es)
EP (1) EP0466914B2 (es)
JP (1) JP3317699B2 (es)
KR (1) KR920701471A (es)
AT (1) ATE153701T1 (es)
AU (1) AU649022B2 (es)
CA (1) CA2049919C (es)
DE (1) DE69126248T3 (es)
ES (1) ES2103803T5 (es)
WO (1) WO1991012336A1 (es)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
AU670108B2 (en) 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
DE4434093A1 (de) * 1994-09-23 1996-03-28 Boehringer Mannheim Gmbh Verfahren zum qualitativen oder/und quantitativen Nachweis einer zu bestimmenden Substanz
US5753517A (en) * 1996-03-29 1998-05-19 University Of British Columbia Quantitative immunochromatographic assays
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
JP4021493B2 (ja) 1996-11-08 2007-12-12 ザ ガヴァメント オブ ザ ユナイテッド ステイツ オブ アメリカ、レプリゼンテッド バイ ザ セクレタリー、 デパートメント オブ ヘルス アンド ヒューマン サーヴィスィズ C型肝炎ウイルス様粒子の合成および精製
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6194222B1 (en) * 1998-01-05 2001-02-27 Biosite Diagnostics, Inc. Methods for monitoring the status of assays and immunoassays
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
US6136610A (en) 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
US6790661B1 (en) * 1999-07-16 2004-09-14 Verax Biomedical, Inc. System for detecting bacteria in blood, blood products, and fluids of tissues
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US6767710B2 (en) * 2001-03-30 2004-07-27 Praxsys Biosystems, Llc Prewetting stop flow test strip
JP2004538453A (ja) * 2001-07-18 2004-12-24 スーリャン ゾー, 全細胞を含有するサンプルに対するラテラルフローアッセイのための試験片
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
US7456025B2 (en) * 2001-08-28 2008-11-25 Porex Corporation Sintered polymer membrane for analyte detection device
US8481334B1 (en) 2001-11-06 2013-07-09 Charm Sciences, Inc. Method of attaching a ligand to a solid support
US20030175991A1 (en) * 2002-03-18 2003-09-18 Ho Winston Z. Optically-assisted high precision pregnancy progress monitoring
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US7517495B2 (en) * 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
EP1664781B1 (en) 2003-09-22 2013-05-08 Quidel Corporation Devices for the detection of multiple analytes in a sample
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20050227370A1 (en) * 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
US7632687B2 (en) * 2004-03-23 2009-12-15 Quidel Corporation Hybrid phase lateral flow assay
ATE479096T1 (de) * 2004-07-29 2010-09-15 Relia Diagnostic Systems Llc Querstromsystem und assay
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
US8124350B2 (en) 2005-04-04 2012-02-28 Biogen Idec Ma Inc. Methods and products for evaluating an immune response to a therapeutic protein
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7871568B2 (en) * 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) * 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
HUE047230T2 (hu) 2006-02-28 2020-04-28 Biogen Ma Inc Gyulladásos és autoimmun betegségek natalizumabbal való kezelésének módszerei
KR20080104343A (ko) 2006-03-03 2008-12-02 엘란 파마슈티칼스, 인크. 나탈리주마브로 염증 및 자가면역 질환을 치료하는 방법
US7527765B2 (en) * 2006-04-11 2009-05-05 Harrogate Holdings Consumer food testing device
AU2007265628B2 (en) 2006-06-23 2012-12-06 Revvity Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays
WO2008021954A2 (en) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Method for distribution of a drug
WO2008061130A2 (en) * 2006-11-15 2008-05-22 Ucp Biosciences, Inc. An improved collecting and testing device and method of use
JP5214723B2 (ja) 2007-04-30 2013-06-19 ナノゲン・インコーポレイテッド 多分析物アッセイ
CN103254308B (zh) 2007-06-15 2015-01-21 厦门大学 H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
US8692873B2 (en) 2009-01-15 2014-04-08 Alverix, Inc. Video-frame data receiver with low frame capture rate
US8422740B2 (en) 2009-01-15 2013-04-16 Scott Dylewski Methods for determining a liquid front position on a test strip
US20120015350A1 (en) * 2009-03-10 2012-01-19 Northwestern University Lateral flow strip and uses thereof
US8377643B2 (en) 2009-03-16 2013-02-19 Abaxis, Inc. Split flow device for analyses of specific-binding partners
AU2010236424B2 (en) * 2009-04-15 2016-03-10 Relia Biotechnologies (Shenzhen) Ltd. Diagnostic devices and related methods
CN102612555A (zh) 2009-10-09 2012-07-25 因威瑟堡善迪诺有限公司 用于检测抗原的装置及其应用
EP2485762B1 (en) 2009-10-11 2017-12-13 Biogen MA Inc. Anti-vla-4 related assays
CA2784791A1 (en) 2009-12-17 2011-07-14 Abaxis, Inc. Novel assays for detecting analytes in samples and kits and compositions related thereto
BR112012017014B1 (pt) 2010-01-11 2021-07-20 Biogen Ma Inc Métodos para detecção de anticorpos de vírus jc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
US10295472B2 (en) 2010-05-05 2019-05-21 Alverix, Inc. Assay reader operable to scan a test strip
WO2011160015A2 (en) 2010-06-17 2011-12-22 Abaxis, Inc. Rotors for immunoassays
WO2012103511A2 (en) 2011-01-27 2012-08-02 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
HUE061244T2 (hu) 2011-05-31 2023-06-28 Biogen Ma Inc A PML kockázat értékelésének módszere
US8211715B1 (en) 2011-11-15 2012-07-03 Harrogate Holdings, Ltd. Co. Consumer food testing device providing remote monitoring
CN104081210B (zh) 2011-12-23 2018-11-30 雅培医护站股份有限公司 具有气动式样本致动的光学测定装置
WO2013096817A2 (en) 2011-12-23 2013-06-27 Abbott Point Of Care Inc Integrated test device for optical detection of microarrays
US9194859B2 (en) 2011-12-23 2015-11-24 Abbott Point Of Care Inc. Reader devices for optical and electrochemical test devices
CN104919055B (zh) 2012-03-09 2018-06-19 因威瑟堡善迪诺有限公司 用单一信号检测多种分析物的方法和组合物
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス, インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
JP2015072249A (ja) * 2013-03-29 2015-04-16 富士フイルム株式会社 被検物質の測定方法、被検物質測定キット及び被検物質測定試薬
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN105189784B (zh) 2013-05-07 2020-06-30 珀金埃尔默健康科学有限公司 用于制备和分析核酸的装置
EP3004334A4 (en) 2013-05-28 2016-12-21 Biogen Ma Inc METHOD FOR ASSESSING A PML RISK
JP6118761B2 (ja) * 2014-06-05 2017-04-19 富士フイルム株式会社 被検物質測定キット及び被検物質の測定方法
ES2816075T3 (es) 2015-08-06 2021-03-31 Lia Diagnostics Inc Pruebas dispersables en agua
WO2017213227A1 (ja) * 2016-06-09 2017-12-14 デンカ生研株式会社 糖鎖抗原を抽出し測定するためのイムノクロマト試験片及び検体添加用デバイス、並びにそれを用いたイムノクロマト法
EP3980182A1 (en) 2019-06-04 2022-04-13 Abbott Toxicology Limited Fluid specimen testing

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169138A (en) * 1974-05-29 1979-09-25 Pharmacia Diagnostics Ab Method for the detection of antibodies
CA1101330A (en) * 1977-09-19 1981-05-19 Ernst A. Fischer Immunological material bonded to carboxylated latex polymer and process for making it
ATE6698T1 (de) * 1979-01-18 1984-03-15 Unilever Nv Verfahren zum nachweis und zur bestimmung spezifisch bindender proteinsubstanzen und mit diesen substanzen bindbarer materialien, testzusammensetzung und reagenziensatz dafuer.
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4351824A (en) * 1981-02-05 1982-09-28 Icl Scientific Polystyrene latex reagents, methods of preparation, and use in immunological procedures
US4419453A (en) * 1981-09-28 1983-12-06 The Dow Chemical Company Immunological agglutination assays with dyed or colored latex and kits
US4419435A (en) * 1982-05-21 1983-12-06 Eastman Kodak Company Photographic products and processes employing 6-heterocyclylazo-3-pyridinol nondiffusible cyan dye-releasing compounds and precursors thereof
US4591570A (en) * 1983-02-02 1986-05-27 Centocor, Inc. Matrix of antibody-coated spots for determination of antigens
US4496654A (en) * 1983-04-08 1985-01-29 Quidel Detection of HCG with solid phase support having avidin coating
US4552839A (en) * 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
US4703017C1 (en) * 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
ES2150428T3 (es) * 1987-04-27 2000-12-01 Unilever Nv Ensayos de union especifica.
US4855240A (en) * 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US4912034A (en) * 1987-09-21 1990-03-27 Biogenex Laboratories Immunoassay test device and method
CA1312544C (en) * 1987-12-21 1993-01-12 James L. Wilcox Chromatographic binding assay devices and methods

Also Published As

Publication number Publication date
JPH04504764A (ja) 1992-08-20
DE69126248T3 (de) 2008-01-24
EP0466914B2 (en) 2007-06-06
CA2049919C (en) 1996-11-19
KR920701471A (ko) 1992-08-11
EP0466914A1 (en) 1992-01-22
WO1991012336A1 (en) 1991-08-22
JP3317699B2 (ja) 2002-08-26
US5096837A (en) 1992-03-17
AU649022B2 (en) 1994-05-12
DE69126248D1 (de) 1997-07-03
DE69126248T2 (de) 1997-09-25
ES2103803T5 (es) 2007-12-16
CA2049919A1 (en) 1991-08-09
EP0466914A4 (en) 1992-06-24
AU7316291A (en) 1991-09-03
EP0466914B1 (en) 1997-05-28
ATE153701T1 (de) 1997-06-15

Similar Documents

Publication Publication Date Title
ATE153701T1 (de) Immunchromatographischer assay und verfahren zur nutzung desselben
ES2013226A4 (es) Metodo y composiciones proveiendo quimicoluminiscencia mejorada de 1,2-dioxanos
ES2075050T3 (es) Peptidos que tienen actividad cooperadora de celulas t.
FI915150A7 (fi) Menetelmät, reagenssit ja testikäyttöpakkaukset biologisten yksiköiden alapopulaatioiden määrittämiseksi
ES2097747T3 (es) Molecula de adhesion intercelular 2 y sus ligandos de union.
ES2055587T3 (es) El uso de agonistas selectivos de gaba-b como agentes antitusivos.
ES550891A0 (es) Procedimiento para solubilizar drogas en propulsores de aerosol a base de clorofluorcarburos
ES2196073T3 (es) Prueba inmunologica de agentes farmacologicos facilitada con detergente.
ES2194116T3 (es) Procedimiento para detectar anticuerpos antipolimero y kit de prueba de diagnostico para uso como ayuda al diagnostico de las enfermedades relacionadas con silicona.
DE69033745D1 (de) Oberflächenaktive zusammensetzungen und verfahren
SE8403630L (sv) Humana proteiner
ES2120169T3 (es) Ensayo de retro-titulacion utilizando dos marcadores diferentes.
GR1000664B (el) Παρασκευη ενωσεων αντι-υπερχοληστερολαιμικης τετραζολης και ενδιαμεσων αυτων.
ES2092170T3 (es) Antagonistas de receptores de fibrinogeno marcados con tritio, su utilizacion y procedimiento para su preparacion.
DE69912827D1 (de) "ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen
SE8003433L (sv) Substituerade pyrido(1,2-a)pyrimidiner
ES2052913T3 (es) Ensayo inmunoquimico en cuanto al factor estimulante de colonias de granulocitos-macrofagos.
BR8707524A (pt) Aparelho de teste de fundicao hepatica
ES267124Y (es) "dispositivo luminoso indicador de averias o desarreglos en instalaciones electricas de uso civil".
IT1241396B (it) Composizioni tensioattive, loro preparazione e loro impiego come agenti antischiuma. (caso 150-5294)
IE40645B1 (en) Visual method for the detection of syphilis and other treponemal diseases, and an antigen preparation useful therein
ES2134879T3 (es) Metalocenos que contienen compuestos de fluorenilo sustituidos en la posicion 9 y uso de los metalocenos.
DE58907569D1 (de) Isomere Trimethylbicyclo[4.3.0]nonan-Derivate.
ES2068863T3 (es) Deteccion inmunologica de atracina y de derivados de atracina.
ATE138196T1 (de) Testverfahren für und behandlung von autoimmunkrankheiten

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 466914

Country of ref document: ES