ES2105003T3 - Forma estable y cristalina del bezafibrato. - Google Patents

Forma estable y cristalina del bezafibrato.

Info

Publication number
ES2105003T3
ES2105003T3 ES93107734T ES93107734T ES2105003T3 ES 2105003 T3 ES2105003 T3 ES 2105003T3 ES 93107734 T ES93107734 T ES 93107734T ES 93107734 T ES93107734 T ES 93107734T ES 2105003 T3 ES2105003 T3 ES 2105003T3
Authority
ES
Spain
Prior art keywords
bezafibrate
stable
crystalline form
chlorobenzoylamino
inn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93107734T
Other languages
English (en)
Inventor
Peter Dr Dipl Chem Morsdorf
Peter Chemikant Maier
Josef Chemieingenieur Schmitt
Kurt-Henning Dr Apothek Ahrens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Pharma GmbH and Co
Original Assignee
Heumann Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Pharma GmbH and Co filed Critical Heumann Pharma GmbH and Co
Application granted granted Critical
Publication of ES2105003T3 publication Critical patent/ES2105003T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/73—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

SE DESCRIBE UNA FORMA CRISTALINA CARACTERIZADA COMO ALFA-FORMA DEL 2 ACIDO PROPIONICO (INN: BEZAFIBRATO, QUE ESTA CARACTERIZADO A TRAVES DE ESPECTROS DE INFRARROJOS FT EN BROMURO DE POTASIO CON BANDAS DE ABSORCION DE LOS SIGUIENTES VALORES DE ONDA: LAS FORMAS OFRECEN EN BASE A SUS PROPIEDADES CRISTALINAS VENTAJAS EN LA ELABORACION GALENICA DE MEDICAMENTOS SOLIDOS.
ES93107734T 1993-05-12 1993-05-12 Forma estable y cristalina del bezafibrato. Expired - Lifetime ES2105003T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93107734A EP0625504B1 (de) 1993-05-12 1993-05-12 Stabile und kristalline Form von Bezafibrat

Publications (1)

Publication Number Publication Date
ES2105003T3 true ES2105003T3 (es) 1997-10-16

Family

ID=8212898

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93107734T Expired - Lifetime ES2105003T3 (es) 1993-05-12 1993-05-12 Forma estable y cristalina del bezafibrato.

Country Status (7)

Country Link
EP (1) EP0625504B1 (es)
JP (1) JPH0753490A (es)
AT (1) ATE157349T1 (es)
DE (1) DE59307210D1 (es)
DK (1) DK0625504T3 (es)
ES (1) ES2105003T3 (es)
GR (1) GR3024704T3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ321575A (en) * 1995-10-30 1999-05-28 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives
CN103951583B (zh) * 2006-12-06 2016-01-06 科内图斯医药公司 一种抑制剂的结晶形式

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2149070C3 (de) 1971-10-01 1978-03-23 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
JPS5649906B2 (en) * 1978-05-12 1981-11-25 Boehringer Mannheim Gmbh Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxy**isoethylacetic acid
JPS54154728A (en) 1978-05-25 1979-12-06 Boehringer Mannheim Gmbh Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxyyisoethylacetic acid
FR2598146B1 (fr) 1986-04-30 1989-01-20 Rech Ind Nouveau procede de preparation de fibrates.

Also Published As

Publication number Publication date
EP0625504A1 (de) 1994-11-23
ATE157349T1 (de) 1997-09-15
DE59307210D1 (de) 1997-10-02
GR3024704T3 (en) 1997-12-31
EP0625504B1 (de) 1997-08-27
JPH0753490A (ja) 1995-02-28
DK0625504T3 (da) 1997-12-08

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