GR3024704T3 - Stable and crystaline form of Bezafibrate. - Google Patents
Stable and crystaline form of Bezafibrate.Info
- Publication number
- GR3024704T3 GR3024704T3 GR970402348T GR970402348T GR3024704T3 GR 3024704 T3 GR3024704 T3 GR 3024704T3 GR 970402348 T GR970402348 T GR 970402348T GR 970402348 T GR970402348 T GR 970402348T GR 3024704 T3 GR3024704 T3 GR 3024704T3
- Authority
- GR
- Greece
- Prior art keywords
- bezafibrate
- stable
- crystaline form
- chlorobenzoylamino
- inn
- Prior art date
Links
- IIBYAHWJQTYFKB-UHFFFAOYSA-N bezafibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1CCNC(=O)C1=CC=C(Cl)C=C1 IIBYAHWJQTYFKB-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000516 bezafibrate Drugs 0.000 title abstract 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/73—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93107734A EP0625504B1 (de) | 1993-05-12 | 1993-05-12 | Stabile und kristalline Form von Bezafibrat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3024704T3 true GR3024704T3 (en) | 1997-12-31 |
Family
ID=8212898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR970402348T GR3024704T3 (en) | 1993-05-12 | 1997-09-11 | Stable and crystaline form of Bezafibrate. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0625504B1 (el) |
| JP (1) | JPH0753490A (el) |
| AT (1) | ATE157349T1 (el) |
| DE (1) | DE59307210D1 (el) |
| DK (1) | DK0625504T3 (el) |
| ES (1) | ES2105003T3 (el) |
| GR (1) | GR3024704T3 (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ321575A (en) * | 1995-10-30 | 1999-05-28 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives |
| KR101125932B1 (ko) * | 2006-12-06 | 2012-03-22 | 아이디유엔 파마슈티칼즈, 인코포레이티드 | (3ｓ)-3-［ｎ-(ｎ'-(2-ｔｅｒｔ-부틸페닐)옥사밀)알라니닐］아미노-5-(2',3',5',6'-테트라플루오로페녹시)-4-옥소펜탄산의 결정 형태 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2149070C3 (de) | 1971-10-01 | 1978-03-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel |
| JPS5649906B2 (en) * | 1978-05-12 | 1981-11-25 | Boehringer Mannheim Gmbh | Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxy**isoethylacetic acid |
| JPS54154728A (en) | 1978-05-25 | 1979-12-06 | Boehringer Mannheim Gmbh | Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxyyisoethylacetic acid |
| FR2598146B1 (fr) | 1986-04-30 | 1989-01-20 | Rech Ind | Nouveau procede de preparation de fibrates. |
-
1993
- 1993-05-12 DE DE59307210T patent/DE59307210D1/de not_active Expired - Fee Related
- 1993-05-12 AT AT93107734T patent/ATE157349T1/de not_active IP Right Cessation
- 1993-05-12 ES ES93107734T patent/ES2105003T3/es not_active Expired - Lifetime
- 1993-05-12 DK DK93107734.1T patent/DK0625504T3/da active
- 1993-05-12 EP EP93107734A patent/EP0625504B1/de not_active Expired - Lifetime
-
1994
- 1994-05-06 JP JP6094153A patent/JPH0753490A/ja not_active Abandoned
-
1997
- 1997-09-11 GR GR970402348T patent/GR3024704T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0753490A (ja) | 1995-02-28 |
| EP0625504A1 (de) | 1994-11-23 |
| ES2105003T3 (es) | 1997-10-16 |
| DK0625504T3 (da) | 1997-12-08 |
| ATE157349T1 (de) | 1997-09-15 |
| EP0625504B1 (de) | 1997-08-27 |
| DE59307210D1 (de) | 1997-10-02 |
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