ES2106763T3 - Un subgrupo de celulas progenitoras humanas. - Google Patents

Un subgrupo de celulas progenitoras humanas.

Info

Publication number
ES2106763T3
ES2106763T3 ES91303960T ES91303960T ES2106763T3 ES 2106763 T3 ES2106763 T3 ES 2106763T3 ES 91303960 T ES91303960 T ES 91303960T ES 91303960 T ES91303960 T ES 91303960T ES 2106763 T3 ES2106763 T3 ES 2106763T3
Authority
ES
Spain
Prior art keywords
cells
human
subgroup
progenital
progenital cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91303960T
Other languages
English (en)
Inventor
Leon Terstappen
Michael Loken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2106763T3 publication Critical patent/ES2106763T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE RECLAMA UNA POBLACION SUSTANCIALMENTE PURA DE CELULAS RADICALES DE PROGENITOR HUMANO QUE CARECEN DE CD38 PERO EXPRESAN CD34. ESTAS CELULAS RADICALES SON PLURIPOTENTES Y PUEDEN FORMAR UNA COLONIA DE BLASTO. ESTAS CELULAS PUEDEN UTILIZARSE EN TRANSPLANTES DEL TUETANO OSEO Y TERAPIA DE GENES.
ES91303960T 1990-05-01 1991-05-01 Un subgrupo de celulas progenitoras humanas. Expired - Lifetime ES2106763T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51710190A 1990-05-01 1990-05-01

Publications (1)

Publication Number Publication Date
ES2106763T3 true ES2106763T3 (es) 1997-11-16

Family

ID=24058370

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91303960T Expired - Lifetime ES2106763T3 (es) 1990-05-01 1991-05-01 Un subgrupo de celulas progenitoras humanas.

Country Status (11)

Country Link
US (2) US5622853A (es)
EP (1) EP0455482B1 (es)
JP (1) JP3070865B2 (es)
AT (1) ATE157119T1 (es)
AU (1) AU641230B2 (es)
CA (1) CA2041258A1 (es)
DE (1) DE69127313T2 (es)
DK (1) DK0455482T3 (es)
ES (1) ES2106763T3 (es)
GR (1) GR3024783T3 (es)
IE (1) IE911145A1 (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571714A (en) * 1988-12-22 1996-11-05 Celtrix Pharmaceuticals, Inc. Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
US5605822A (en) * 1989-06-15 1997-02-25 The Regents Of The University Of Michigan Methods, compositions and devices for growing human hematopoietic cells
US5635386A (en) 1989-06-15 1997-06-03 The Regents Of The University Of Michigan Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture
US5635387A (en) * 1990-04-23 1997-06-03 Cellpro, Inc. Methods and device for culturing human hematopoietic cells and their precursors
US5840580A (en) * 1990-05-01 1998-11-24 Becton Dickinson And Company Phenotypic characterization of the hematopoietic stem cell
ES2180539T3 (es) * 1991-10-23 2003-02-16 Nexell Therapeutics Inc Metodos para expandir selectivamente celulas madre.
US6004807A (en) * 1992-03-30 1999-12-21 Schering Corporation In vitro generation of human dendritic cells
EP0563485A1 (en) * 1992-03-30 1993-10-06 Schering-Plough In vitro generation of human dendritic cells and uses thereof
US5436151A (en) * 1992-04-03 1995-07-25 Regents Of The University Of Minnesota Method for culturing human hematopoietic stem cells in vitro
US5460964A (en) * 1992-04-03 1995-10-24 Regents Of The University Of Minnesota Method for culturing hematopoietic cells
DE69309487T2 (de) * 1992-11-13 1997-10-23 Univ Washington Peripheralisierung hämatopoietischer stammzellen
JPH08506007A (ja) * 1992-11-16 1996-07-02 アプライド イミューン サイエンシーズ，インコーポレイテッド 多能性の休止状態の幹細胞集団
CA2155515A1 (en) * 1993-02-19 1994-09-01 Wendy Waegell Expansion of stem cells in long term bone marrow cultures by neutralization of tgf-.beta.
JPH08509720A (ja) * 1993-05-03 1996-10-15 ジェネンテク、インコーポレイテッド 白血球接着阻害
US6555324B1 (en) * 1993-11-04 2003-04-29 Becton Dickinson & Company Method to distinguish hematopoietic progenitor cells
EP0662512A3 (en) * 1993-12-20 1997-01-15 Becton Dickinson Co Human hematopoietic stem cells.
US5972703A (en) 1994-08-12 1999-10-26 The Regents Of The University Of Michigan Bone precursor cells: compositions and methods
DE69531432T2 (de) * 1994-09-23 2004-07-29 Becton Dickinson And Co. Verfahren zur Unterscheidung von granulomoncytischen Progenitoren in einer Population von CD34+ Zellen
US5874266A (en) * 1997-03-27 1999-02-23 Palsson; Bernhard O. Targeted system for removing tumor cells from cell populations
WO1999024554A2 (en) 1997-11-12 1999-05-20 University Of Pittsburgh Isolation, characterization, and identification of dendritic like cells and methods of using same
US20020034819A1 (en) 1998-02-23 2002-03-21 Alan K. Smith Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
US7799324B2 (en) 2001-12-07 2010-09-21 Geron Corporation Using undifferentiated embryonic stem cells to control the immune system
IL162130A0 (en) 2001-12-07 2005-11-20 Robarts Res Inst Hematopoietic cells from human embryonic stem cells
JP4238138B2 (ja) * 2001-12-22 2009-03-11 ４−アンチボディ アーゲー 遺伝的に修飾された脊椎動物前駆体リンパ球の生成方法及び異種結合タンパク質の産生を目的としたその使用。
US7595148B2 (en) 2003-01-25 2009-09-29 Irm Llc Methods and compositions for modulating T lymphocytes
EP1613742A2 (en) * 2003-04-08 2006-01-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
AU2004288722A1 (en) 2003-11-04 2005-05-26 U.S. Department Of Veterans Affairs Stem cell culture medium and method of using said medium and the cells
EP1851308B1 (en) * 2005-02-02 2013-08-21 NewSouth Innovations Pty Limited Cd4+ cd25+ t-cells activated to a specific antigen
JP5649786B2 (ja) 2006-03-07 2015-01-07 ギータ シュロフ ヒト胚性幹細胞およびそれらの誘導体を含む組成物、使用方法、ならびに調製方法
WO2008014555A1 (en) 2006-08-02 2008-02-07 Newsouth Innovations Pty Limited Method of identifying cd4+cd25+ t cells activated to an antigen which express cd8
EP2359164A4 (en) * 2008-12-10 2012-05-30 Abqmr Inc CORE MAGNETIC RESONANCE DEVICE, METHOD AND ASSOCIATED TECHNOLOGY
US20120177618A1 (en) * 2009-07-14 2012-07-12 Massachusetts Institute Of Technology Hematopoietic stromal progenitor cells and uses thereof
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
WO2014024859A1 (ja) 2012-08-07 2014-02-13 テイ・エス テック株式会社 部材の取付構造および乗物用シート
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
EP3060670B1 (en) * 2013-10-24 2019-07-10 Ospedale San Raffaele S.r.l. Method

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680383A (en) * 1979-03-20 1987-07-14 Ortho Pharmaceutical Monoclonal antibody to human T cells
US4803262A (en) * 1979-10-09 1989-02-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human cytotoxic and suppressor T cells, antibody, and methods
US4624925A (en) * 1979-12-04 1986-11-25 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to a human early thymocyte antigens, antibody, and methods
US4798806A (en) * 1980-01-08 1989-01-17 Ortho Pharmaceutical Corporation Compositions and methods using a monoclonal antibody to a human T cell antigen
US4714680B1 (en) * 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
JPS641A (en) * 1987-03-25 1989-01-05 Nippon Ekishiyou Kk Masking of agent having strong smell
US4845653A (en) * 1987-05-07 1989-07-04 Becton, Dickinson And Company Method of displaying multi-parameter data sets to aid in the analysis of data characteristics
ATE81724T1 (de) * 1987-11-09 1992-11-15 Becton Dickinson Co Verfahren zur analyse haematopoietischer zellen in einer probe.
US4987086A (en) * 1987-11-30 1991-01-22 Becton, Dickinson And Company Method for analysis of subpopulations of cells
WO1989008114A1 (en) * 1988-02-25 1989-09-08 The General Hospital Corporation Rapid immunoselection cloning method
US5087570A (en) * 1988-05-10 1992-02-11 Weissman Irving L Homogeneous mammalian hematopoietic stem cell composition
US5047321A (en) * 1988-06-15 1991-09-10 Becton Dickinson & Co. Method for analysis of cellular components of a fluid
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell

Also Published As

Publication number Publication date
ATE157119T1 (de) 1997-09-15
EP0455482A3 (en) 1992-09-02
CA2041258A1 (en) 1991-11-02
JPH0576354A (ja) 1993-03-30
US5583033A (en) 1996-12-10
DE69127313T2 (de) 1998-01-22
DE69127313D1 (de) 1997-09-25
AU641230B2 (en) 1993-09-16
AU7429391A (en) 1991-11-07
IE911145A1 (en) 1991-11-06
EP0455482A2 (en) 1991-11-06
DK0455482T3 (da) 1998-04-06
JP3070865B2 (ja) 2000-07-31
EP0455482B1 (en) 1997-08-20
US5622853A (en) 1997-04-22
GR3024783T3 (en) 1998-01-30

Similar Documents

Publication Publication Date Title
ES2106763T3 (es) Un subgrupo de celulas progenitoras humanas.
Wei et al. Functional tooth restoration by allogeneic mesenchymal stem cell-based bio-root regeneration in swine
CY1107121T1 (el) Ρυθμιση διαφοροποιησης αιματοποιητικων βλαστικων κυτταρων με τη χρηση ανθρωπινων μεσυγχυματικων βλαστικων κυτταρων
ATE296875T1 (de) Verfahren zur herstellung von genetisch modifizierten cd34-negativen, adhärent wachsenden hämatopoietischen stammzellen
Telles et al. Pulp tissue from primary teeth: new source of stem cells
WO1995011048A3 (en) METHODS AND COMPOSITIONS OF A BIOARTIFICIAL KIDNEY SUITABLE FOR USE IN VIVO OR $i(EX VIVO)
TR200200897T2 (tr) Melez matrisler ve melez matriks karışımları
JP2002517227A5 (ja) 造血幹細胞を試験管内で維持する方法と組成物
EP2048228B8 (en) Human liver progenitors
AR241314A1 (es) Aislado de adn, vector en base en dicho aislado cultivo de celulas tratadas con dicho vector y preparacion de factor viii humano funcional.
YU46723B (sh) Ekspresija, prerada i sekrecija heterologog proteina pomoću kvasca
MY119132A (en) Protein delivery by gene therapy
LV12085A (lv) Dendritiskas sunas stimulejosais faktors
WO1994010203A3 (en) Op-3-induced morphogenesis
Kriebel et al. Anaerobic co-culture of mesenchymal stem cells and anaerobic pathogens-a new in vitro model system
Shilpa et al. Stem cells: Boon to dentistry and medicine
DK0843731T3 (da) Adenovirusvektorer til genterapi
ATE15693T1 (de) Zellkultur-verfahren.
ATE243741T1 (de) Zufuhr von genprodukten mittels mesangium-zellen
ATE225183T1 (de) Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
Fioretti et al. Human bone marrow‐derived cells: An attractive source to populate dermal substitutes
Arase et al. Culture of human outer root sheath cells from plucked hair follicles in serum-free conditions
PT765398E (pt) Populacao de celulas enriquecedoras em progenitores mieloides e linfoides e metodos de as fazer e utilizar
DE60308917D1 (de) Verwendung einer Zusammensetzung enthaltend 5-Androsten-3beta,17alpha-diol
Jackson et al. Induction of chimerism in mice using human MHC class I-mismatched Hoechst 33342 side population donor stem cells

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 455482

Country of ref document: ES